A small-cell lung cancer genome with complex signatures of tobacco exposure

Nature

Volumn 463, Issue 7278, 2010, Pages 184-190

  Pleasance, Erin D ^a   Stephens, Philip J ^a   O'Meara, Sarah ^a,b   McBride, David J ^a   Meynert, Alison ^c   Jones, David ^a   Lin, Meng Lay ^a   Beare, David ^a   Lau, King Wai ^a   Greenman, Chris ^a   Varela, Ignacio ^a   Nik Zainal, Serena ^a   Davies, Helen R ^a   Ordõez, Gonzalo R ^a   Mudie, Laura J ^a   Latimer, Calli ^a   Edkins, Sarah ^a   Stebbings, Lucy ^a   Chen, Lina ^a   Jia, Mingming ^a   Leroy, Catherine ^a   Marshall, John ^a   Menzies, Andrew ^a   Butler, Adam ^a   Teague, Jon W ^a   Mangion, Jonathon ^b   Sun, Yongming A ^d   McLaughlin, Stephen F ^e   Peckham, Heather E ^e   Tsung, Eric F ^e   Costa, Gina L ^e   Lee, Clarence C ^e   Minna, John D ^f   Gazdar, Adi ^f   Birney, Ewan ^c   Rhodes, Michael D ^d   McKernan, Kevin J ^e   Stratton, Michael R ^a,g   Futreal, P Andrew ^a   Campbell, Peter J ^a,h   more..

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b Life Technologies   (United Kingdom)

^c EUROPEAN BIOINFORMATICS INSTITUTE   (United Kingdom)

^d Life Technologies Corporation   (United States)

^e Life Technologies   (United States)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^g INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^h UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; HYBRID PROTEIN; PROTEIN CHD7; PROTEIN PVT1 CHD7; UNCLASSIFIED DRUG;

CANCER; DNA; GENE EXPRESSION; GENOME; MUTATION; RESPIRATORY DISEASE; SMOKING; TOBACCO;

ARTICLE; CIGARETTE SMOKING; CONTROLLED STUDY; DNA REPAIR; EXON; GENE EXPRESSION; GENE NUMBER; GENE SEQUENCE; GENETIC VARIABILITY; HUMAN; HUMAN CELL; KARYOTYPE; LUNG SMALL CELL CANCER; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROMOTER REGION; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SOMATIC MUTATION;

CARCINOGENS; CELL LINE, TUMOR; DNA COPY NUMBER VARIATIONS; DNA DAMAGE; DNA HELICASES; DNA MUTATIONAL ANALYSIS; DNA REPAIR; DNA-BINDING PROTEINS; EXONS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME, HUMAN; HUMANS; LUNG NEOPLASMS; MUTAGENESIS, INSERTIONAL; MUTATION; PROMOTER REGIONS, GENETIC; SEQUENCE DELETION; SMALL CELL LUNG CARCINOMA; SMOKING; TOBACCO;

NICOTIANA TABACUM;

EID: 74449085934     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature08629     Document Type: Article

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