Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing

Science Translational Medicine

Volumn 5, Issue 197, 2013, Pages

  Hoang, Margaret L ^a   Chen, Chung Hsin ^b   Sidorenko, Viktoriya S ^c   He, Jian ^a   Dickman, Kathleen G ^c   Yun, Byeong Hwa ^d   Moriya, Masaaki ^c   Niknafs, Noushin ^e   Douville, Christopher ^e   Karchin, Rachel ^e   Turesky, Robert J ^d   Pu, Yeong Shiau ^b   Vogelstein, Bert ^a   Papadopoulos, Nickolas ^a   Grollman, Arthur P ^c   Kinzler, Kenneth W ^a   Rosenquist, Thomas A ^c  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c STONY BROOK UNIVERSITY   (United States)

^d WADSWORTH CENTER   (United States)

^e Johns Hopkins University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARISTOLOCHIC ACID; DEOXYADENOSINE; DNA; TRINUCLEOTIDE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COHORT ANALYSIS; CONSENSUS SEQUENCE; CONTROLLED STUDY; DRUG EXPOSURE; EXOME; FEMALE; GENE MUTATION; GENE SEQUENCE; HUMAN; HUMAN TISSUE; MALE; MUTATIONAL SIGNATURE; NUCLEIC ACID BASE SUBSTITUTION; ONCOGENE; PRIORITY JOURNAL; RNA SPLICING; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; SOMATIC MUTATION; TAIWAN; TP53 GENE; TRANSITIONAL CELL CARCINOMA; TUMOR SUPPRESSOR GENE;

AGED; ARISTOLOCHIC ACIDS; EXOME; FEMALE; HUMANS; MALE; MIDDLE AGED; MUTATION; SEQUENCE ANALYSIS, DNA; UROLOGIC NEOPLASMS; UROTHELIUM;

EID: 84883894030     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.3006200     Document Type: Article

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