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Volumn 137, Issue 3, 2009, Pages

In Vitro Recapitulating of TP53 Mutagenesis in Hepatocellular Carcinoma Associated With Dietary Aflatoxin B1 Exposure

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN B1; IMIDAZOLE; PROTEIN P53;

EID: 69249129569     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2009.06.002     Document Type: Article
Times cited : (73)

References (49)
  • 1
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: epidemiology and molecular carcinogenesis
    • El-Serag H.B., and Rudolph K.L. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 132 (2007) 2557-2576
    • (2007) Gastroenterology , vol.132 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 2
    • 0141491273 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • Llovet J.M., Burroughs A., and Bruix J. Hepatocellular carcinoma. Lancet 362 (2003) 1907-1917
    • (2003) Lancet , vol.362 , pp. 1907-1917
    • Llovet, J.M.1    Burroughs, A.2    Bruix, J.3
  • 3
    • 7044229778 scopus 로고    scopus 로고
    • Primary liver cancer: worldwide incidence and trends
    • Bosch F.X., Ribes J., Diaz M., et al. Primary liver cancer: worldwide incidence and trends. Gastroenterology 127 (2004) S5-S16
    • (2004) Gastroenterology , vol.127
    • Bosch, F.X.1    Ribes, J.2    Diaz, M.3
  • 4
    • 20344392430 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: epidemiology, risk factors, and screening
    • Sherman M. Hepatocellular carcinoma: epidemiology, risk factors, and screening. Semin Liver Dis 25 (2005) 143-154
    • (2005) Semin Liver Dis , vol.25 , pp. 143-154
    • Sherman, M.1
  • 5
    • 7044260779 scopus 로고    scopus 로고
    • Environmental factors and risk for hepatocellular carcinoma
    • Yu M.C., and Yuan J.M. Environmental factors and risk for hepatocellular carcinoma. Gastroenterology 127 (2004) S72-S78
    • (2004) Gastroenterology , vol.127
    • Yu, M.C.1    Yuan, J.M.2
  • 6
    • 0038049147 scopus 로고    scopus 로고
    • Translational strategies for cancer prevention in liver
    • Kensler T.W., Qian G.S., Chen J.G., et al. Translational strategies for cancer prevention in liver. Nat Rev Cancer 3 (2003) 321-329
    • (2003) Nat Rev Cancer , vol.3 , pp. 321-329
    • Kensler, T.W.1    Qian, G.S.2    Chen, J.G.3
  • 7
  • 8
    • 0035067203 scopus 로고    scopus 로고
    • The chemistry and biology of aflatoxin B(1): from mutational spectrometry to carcinogenesis
    • Smela M.E., Currier S.S., Bailey E.A., et al. The chemistry and biology of aflatoxin B(1): from mutational spectrometry to carcinogenesis. Carcinogenesis 22 (2001) 535-545
    • (2001) Carcinogenesis , vol.22 , pp. 535-545
    • Smela, M.E.1    Currier, S.S.2    Bailey, E.A.3
  • 9
    • 0036856464 scopus 로고    scopus 로고
    • The toxicology of aflatoxins as a basis for public health decisions
    • Wild C.P., and Turner P.C. The toxicology of aflatoxins as a basis for public health decisions. Mutagenesis 17 (2002) 471-481
    • (2002) Mutagenesis , vol.17 , pp. 471-481
    • Wild, C.P.1    Turner, P.C.2
  • 10
    • 34248379012 scopus 로고    scopus 로고
    • Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database
    • Petitjean A., Mathe E., Kato S., et al. Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database. Hum Mutat 28 (2007) 622-629
    • (2007) Hum Mutat , vol.28 , pp. 622-629
    • Petitjean, A.1    Mathe, E.2    Kato, S.3
  • 11
    • 34047210411 scopus 로고    scopus 로고
    • TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer
    • Hussain S.P., Schwank J., Staib F., et al. TP53 mutations and hepatocellular carcinoma: insights into the etiology and pathogenesis of liver cancer. Oncogene 26 (2007) 2166-2176
    • (2007) Oncogene , vol.26 , pp. 2166-2176
    • Hussain, S.P.1    Schwank, J.2    Staib, F.3
  • 12
    • 0028986147 scopus 로고
    • Oxidation of aflatoxin B1 by bacterial recombinant human cytochrome P450 enzymes
    • Ueng Y.F., Shimada T., Yamazaki H., et al. Oxidation of aflatoxin B1 by bacterial recombinant human cytochrome P450 enzymes. Chem Res Toxicol 8 (1995) 218-225
    • (1995) Chem Res Toxicol , vol.8 , pp. 218-225
    • Ueng, Y.F.1    Shimada, T.2    Yamazaki, H.3
  • 13
    • 0030339769 scopus 로고    scopus 로고
    • The kinetics of aflatoxin B1 oxidation by human cDNA-expressed and human liver microsomal cytochromes P450 1A2 and 3A4
    • Gallagher E.P., Kunze K.L., Stapleton P.L., et al. The kinetics of aflatoxin B1 oxidation by human cDNA-expressed and human liver microsomal cytochromes P450 1A2 and 3A4. Toxicol Appl Pharmacol 141 (1996) 595-606
    • (1996) Toxicol Appl Pharmacol , vol.141 , pp. 595-606
    • Gallagher, E.P.1    Kunze, K.L.2    Stapleton, P.L.3
  • 14
    • 0031284677 scopus 로고    scopus 로고
    • Aflatoxin B1-induced DNA adduct formation and p53 mutations in CYP450-expressing human liver cell lines
    • Mace K., Aguilar F., Wang J.S., et al. Aflatoxin B1-induced DNA adduct formation and p53 mutations in CYP450-expressing human liver cell lines. Carcinogenesis 18 (1997) 1291-1297
    • (1997) Carcinogenesis , vol.18 , pp. 1291-1297
    • Mace, K.1    Aguilar, F.2    Wang, J.S.3
  • 15
    • 0001200079 scopus 로고
    • Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro
    • Essigmann J.M., Croy R.G., Nadzan A.M., et al. Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro. Proc Natl Acad Sci U S A 74 (1977) 1870-1874
    • (1977) Proc Natl Acad Sci U S A , vol.74 , pp. 1870-1874
    • Essigmann, J.M.1    Croy, R.G.2    Nadzan, A.M.3
  • 17
    • 0030610234 scopus 로고    scopus 로고
    • Reaction of aflatoxin B1 exo-8,9-epoxide with DNA: kinetic analysis of covalent binding and DNA-induced hydrolysis
    • Johnson W.W., and Guengerich F.P. Reaction of aflatoxin B1 exo-8,9-epoxide with DNA: kinetic analysis of covalent binding and DNA-induced hydrolysis. Proc Natl Acad Sci U S A 94 (1997) 6121-6125
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 6121-6125
    • Johnson, W.W.1    Guengerich, F.P.2
  • 18
    • 0032543419 scopus 로고    scopus 로고
    • Activation and detoxication of aflatoxin B1
    • Guengerich F.P., Johnson W.W., Shimada T., et al. Activation and detoxication of aflatoxin B1. Mutat Res 402 (1998) 121-128
    • (1998) Mutat Res , vol.402 , pp. 121-128
    • Guengerich, F.P.1    Johnson, W.W.2    Shimada, T.3
  • 20
    • 0029912231 scopus 로고    scopus 로고
    • Mutational properties of the primary aflatoxin B1-DNA adduct
    • Bailey E.A., Iyer R.S., Stone M.P., et al. Mutational properties of the primary aflatoxin B1-DNA adduct. Proc Natl Acad Sci U S A 93 (1996) 1535-1539
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 1535-1539
    • Bailey, E.A.1    Iyer, R.S.2    Stone, M.P.3
  • 21
    • 0032765557 scopus 로고    scopus 로고
    • Site-specific synthesis of aflatoxin B(1) adducts within an oligodeoxyribonucleotide containing the human p53 codon 249 sequence
    • Jones W.R., Johnston D.S., and Stone M.P. Site-specific synthesis of aflatoxin B(1) adducts within an oligodeoxyribonucleotide containing the human p53 codon 249 sequence. Chem Res Toxicol 12 (1999) 707-714
    • (1999) Chem Res Toxicol , vol.12 , pp. 707-714
    • Jones, W.R.1    Johnston, D.S.2    Stone, M.P.3
  • 22
    • 0037076317 scopus 로고    scopus 로고
    • The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma
    • Smela M.E., Hamm M.L., Henderson P.T., et al. The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma. Proc Natl Acad Sci U S A 99 (2002) 6655-6660
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 6655-6660
    • Smela, M.E.1    Hamm, M.L.2    Henderson, P.T.3
  • 23
    • 0029810641 scopus 로고    scopus 로고
    • Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage λ transgene target
    • Jakubczak J.L., Merlino G., French J.E., et al. Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage λ transgene target. Proc Natl Acad Sci U S A 93 (1996) 9073-9078
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 9073-9078
    • Jakubczak, J.L.1    Merlino, G.2    French, J.E.3
  • 24
    • 33747874880 scopus 로고    scopus 로고
    • Investigating human cancer etiology by DNA lesion footprinting and mutagenicity analysis
    • Besaratinia A., and Pfeifer G.P. Investigating human cancer etiology by DNA lesion footprinting and mutagenicity analysis. Carcinogenesis 27 (2006) 1526-1537
    • (2006) Carcinogenesis , vol.27 , pp. 1526-1537
    • Besaratinia, A.1    Pfeifer, G.P.2
  • 25
    • 23744463885 scopus 로고    scopus 로고
    • Detailed review of transgenic rodent mutation assays
    • Lambert I.B., Singer T.M., Boucher S.E., et al. Detailed review of transgenic rodent mutation assays. Mutat Res 590 (2005) 1-280
    • (2005) Mutat Res , vol.590 , pp. 1-280
    • Lambert, I.B.1    Singer, T.M.2    Boucher, S.E.3
  • 26
    • 0025918336 scopus 로고
    • Aflatoxin B1-DNA adducts and hepatitis B virus antigens in hepatocellular carcinoma and non-tumorous liver tissue
    • Zhang Y.J., Chen C.J., Lee C.S., et al. Aflatoxin B1-DNA adducts and hepatitis B virus antigens in hepatocellular carcinoma and non-tumorous liver tissue. Carcinogenesis 12 (1991) 2247-2452
    • (1991) Carcinogenesis , vol.12 , pp. 2247-2452
    • Zhang, Y.J.1    Chen, C.J.2    Lee, C.S.3
  • 27
    • 0348140585 scopus 로고    scopus 로고
    • Abasic sites in DNA: repair and biological consequences in Saccharomyces cerevisiae
    • Boiteux S., and Guillet M. Abasic sites in DNA: repair and biological consequences in Saccharomyces cerevisiae. DNA Repair (Amst) 3 (2004) 1-12
    • (2004) DNA Repair (Amst) , vol.3 , pp. 1-12
    • Boiteux, S.1    Guillet, M.2
  • 28
    • 0035836977 scopus 로고    scopus 로고
    • Terminal transferase-dependent PCR (TD-PCR) for in vivo UV photofootprinting of vertebrate cells
    • Chen H.H., Kontaraki J., Bonifer C., et al. Terminal transferase-dependent PCR (TD-PCR) for in vivo UV photofootprinting of vertebrate cells. Sci STKE 2001 (2001) PL1
    • (2001) Sci STKE , vol.2001
    • Chen, H.H.1    Kontaraki, J.2    Bonifer, C.3
  • 29
    • 0032954049 scopus 로고    scopus 로고
    • Quantitation and mapping of aflatoxin B1-induced DNA damage in genomic DNA using aflatoxin B1-8,9-epoxide and microsomal activation systems
    • Denissenko M.F., Cahill J., Koudriakova T.B., et al. Quantitation and mapping of aflatoxin B1-induced DNA damage in genomic DNA using aflatoxin B1-8,9-epoxide and microsomal activation systems. Mutat Res 425 (1999) 205-211
    • (1999) Mutat Res , vol.425 , pp. 205-211
    • Denissenko, M.F.1    Cahill, J.2    Koudriakova, T.B.3
  • 30
    • 0032506782 scopus 로고    scopus 로고
    • The p53 codon 249 mutational hotspot in hepatocellular carcinoma is not related to selective formation or persistence of aflatoxin B1 adducts
    • Denissenko M.F., Koudriakova T.B., Smith L., et al. The p53 codon 249 mutational hotspot in hepatocellular carcinoma is not related to selective formation or persistence of aflatoxin B1 adducts. Oncogene 17 (1998) 3007-3014
    • (1998) Oncogene , vol.17 , pp. 3007-3014
    • Denissenko, M.F.1    Koudriakova, T.B.2    Smith, L.3
  • 31
    • 22544452379 scopus 로고    scopus 로고
    • DNA lesions induced by UV A1 and B radiation in human cells: comparative analyses in the overall genome and in the p53 tumor suppressor gene
    • Besaratinia A., Synold T.W., Chen H.H., et al. DNA lesions induced by UV A1 and B radiation in human cells: comparative analyses in the overall genome and in the p53 tumor suppressor gene. Proc Natl Acad Sci U S A 102 (2005) 10058-10063
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 10058-10063
    • Besaratinia, A.1    Synold, T.W.2    Chen, H.H.3
  • 32
    • 65649143300 scopus 로고    scopus 로고
    • DNA-lesion mapping in mammalian cells
    • Besaratinia A., and Pfeifer G.P. DNA-lesion mapping in mammalian cells. Methods 48 (2009) 35-39
    • (2009) Methods , vol.48 , pp. 35-39
    • Besaratinia, A.1    Pfeifer, G.P.2
  • 33
    • 0023663101 scopus 로고
    • Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene
    • Mellon I., Spivak G., and Hanawalt P.C. Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene. Cell 51 (1987) 241-249
    • (1987) Cell , vol.51 , pp. 241-249
    • Mellon, I.1    Spivak, G.2    Hanawalt, P.C.3
  • 34
    • 5444239783 scopus 로고    scopus 로고
    • Environmental and chemical carcinogenesis
    • Wogan G.N., Hecht S.S., Felton J.S., et al. Environmental and chemical carcinogenesis. Semin Cancer Biol 14 (2004) 473-486
    • (2004) Semin Cancer Biol , vol.14 , pp. 473-486
    • Wogan, G.N.1    Hecht, S.S.2    Felton, J.S.3
  • 35
    • 0037716639 scopus 로고    scopus 로고
    • Have environmental mutagens caused oncomutations in people?
    • Thilly W.G. Have environmental mutagens caused oncomutations in people?. Nat Genet 34 (2003) 255-259
    • (2003) Nat Genet , vol.34 , pp. 255-259
    • Thilly, W.G.1
  • 36
    • 0029813259 scopus 로고    scopus 로고
    • Mutational specificity of aflatoxin B1. Comparison of in vivo host-mediated assay with in vitro S9 metabolic activation
    • Prieto-Alamo M.J., Jurado J., Abril N., et al. Mutational specificity of aflatoxin B1. Comparison of in vivo host-mediated assay with in vitro S9 metabolic activation. Carcinogenesis 17 (1996) 1997-2002
    • (1996) Carcinogenesis , vol.17 , pp. 1997-2002
    • Prieto-Alamo, M.J.1    Jurado, J.2    Abril, N.3
  • 37
    • 0037094748 scopus 로고    scopus 로고
    • Variability in aflatoxin B(1)-macromolecular binding and relationship to biotransformation enzyme expression in human prenatal and adult liver
    • Doi A.M., Patterson P.E., and Gallagher E.P. Variability in aflatoxin B(1)-macromolecular binding and relationship to biotransformation enzyme expression in human prenatal and adult liver. Toxicol Appl Pharmacol 181 (2002) 48-59
    • (2002) Toxicol Appl Pharmacol , vol.181 , pp. 48-59
    • Doi, A.M.1    Patterson, P.E.2    Gallagher, E.P.3
  • 38
    • 54249147965 scopus 로고    scopus 로고
    • Comparison of metabolite profiles generated in Aroclor-induced rat liver and human liver subcellular fractions: considerations for in vitro genotoxicity hazard assessment
    • Obach R.S., and Dobo K.L. Comparison of metabolite profiles generated in Aroclor-induced rat liver and human liver subcellular fractions: considerations for in vitro genotoxicity hazard assessment. Environ Mol Mutagen 49 (2008) 631-641
    • (2008) Environ Mol Mutagen , vol.49 , pp. 631-641
    • Obach, R.S.1    Dobo, K.L.2
  • 39
    • 0019161366 scopus 로고
    • A high-pressure liquid chromatography study on the removal of DNA-bound aflatoxin B1 in rat liver and in vitro
    • Hertzog P.J., Lindsay Smith J.R., Garner R.C., et al. A high-pressure liquid chromatography study on the removal of DNA-bound aflatoxin B1 in rat liver and in vitro. Carcinogenesis 1 (1980) 787-793
    • (1980) Carcinogenesis , vol.1 , pp. 787-793
    • Hertzog, P.J.1    Lindsay Smith, J.R.2    Garner, R.C.3
  • 40
    • 0019364067 scopus 로고
    • Temporal patterns of covalent DNA adducts in rat liver after single and multiple doses of aflatoxin B1
    • Croy R.G., and Wogan G.N. Temporal patterns of covalent DNA adducts in rat liver after single and multiple doses of aflatoxin B1. Cancer Res 41 (1981) 197-203
    • (1981) Cancer Res , vol.41 , pp. 197-203
    • Croy, R.G.1    Wogan, G.N.2
  • 41
    • 0031844196 scopus 로고    scopus 로고
    • Refined structure of the doubly intercalated d(TATAFBGCATA)2 aflatoxin B1 adduct
    • Jones W.R., Johnston D.S., and Stone M.P. Refined structure of the doubly intercalated d(TATAFBGCATA)2 aflatoxin B1 adduct. Chem Res Toxicol 11 (1998) 873-881
    • (1998) Chem Res Toxicol , vol.11 , pp. 873-881
    • Jones, W.R.1    Johnston, D.S.2    Stone, M.P.3
  • 42
    • 0037197682 scopus 로고    scopus 로고
    • Mispairing of the 8,9-dihydro-8-(N7-guanyl)-9-hydroxy-aflatoxin B1 adduct with deoxyadenosine results in extrusion of the mismatched dA toward the major groove
    • Giri I., Johnston D.S., and Stone M.P. Mispairing of the 8,9-dihydro-8-(N7-guanyl)-9-hydroxy-aflatoxin B1 adduct with deoxyadenosine results in extrusion of the mismatched dA toward the major groove. Biochemistry 41 (2002) 5462-5472
    • (2002) Biochemistry , vol.41 , pp. 5462-5472
    • Giri, I.1    Johnston, D.S.2    Stone, M.P.3
  • 43
    • 0019853405 scopus 로고
    • Excision repair of aflatoxin B1-DNA adducts in human fibroblasts
    • Leadon S.A., Tyrrell R.M., and Cerutti P.A. Excision repair of aflatoxin B1-DNA adducts in human fibroblasts. Cancer Res 41 (1981) 5125-5129
    • (1981) Cancer Res , vol.41 , pp. 5125-5129
    • Leadon, S.A.1    Tyrrell, R.M.2    Cerutti, P.A.3
  • 44
    • 3042697167 scopus 로고    scopus 로고
    • Aflatoxin B1 formamidopyrimidine adducts are preferentially repaired by the nucleotide excision repair pathway in vivo
    • Alekseyev Y.O., Hamm M.L., and Essigmann J.M. Aflatoxin B1 formamidopyrimidine adducts are preferentially repaired by the nucleotide excision repair pathway in vivo. Carcinogenesis 25 (2004) 1045-1051
    • (2004) Carcinogenesis , vol.25 , pp. 1045-1051
    • Alekseyev, Y.O.1    Hamm, M.L.2    Essigmann, J.M.3
  • 45
    • 0036828029 scopus 로고    scopus 로고
    • Altered DNA mutation spectrum in aflatoxin b1-treated transgenic mice that express the hepatitis B virus x protein
    • Madden C.R., Finegold M.J., and Slagle B.L. Altered DNA mutation spectrum in aflatoxin b1-treated transgenic mice that express the hepatitis B virus x protein. J Virol 76 (2002) 11770-11774
    • (2002) J Virol , vol.76 , pp. 11770-11774
    • Madden, C.R.1    Finegold, M.J.2    Slagle, B.L.3
  • 46
    • 53249142127 scopus 로고    scopus 로고
    • Aflatoxin B1-induced TP53 mutational pattern in normal human cells using the FASAY (functional analysis of separated alleles in yeast)
    • Paget V., Sichel F., Garon D., et al. Aflatoxin B1-induced TP53 mutational pattern in normal human cells using the FASAY (functional analysis of separated alleles in yeast). Mutat Res 656 (2008) 55-61
    • (2008) Mutat Res , vol.656 , pp. 55-61
    • Paget, V.1    Sichel, F.2    Garon, D.3
  • 47
    • 0035910281 scopus 로고    scopus 로고
    • Similarities in sunlight-induced mutational spectra of CpG-methylated transgenes and the p53 gene in skin cancer point to an important role of 5-methylcytosine residues in solar UV mutagenesis
    • You Y.H., and Pfeifer G.P. Similarities in sunlight-induced mutational spectra of CpG-methylated transgenes and the p53 gene in skin cancer point to an important role of 5-methylcytosine residues in solar UV mutagenesis. J Mol Biol 305 (2001) 389-399
    • (2001) J Mol Biol , vol.305 , pp. 389-399
    • You, Y.H.1    Pfeifer, G.P.2
  • 48
    • 0027337609 scopus 로고
    • Aflatoxin B1 induces the transversion of G to T in codon 249 of the p53 tumor suppressor gene in human hepatocytes
    • Aguilar F., Hussain S.P., and Cerutti P. Aflatoxin B1 induces the transversion of G to T in codon 249 of the p53 tumor suppressor gene in human hepatocytes. Proc Natl Acad Sci U S A 90 (1993) 8586-8590
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 8586-8590
    • Aguilar, F.1    Hussain, S.P.2    Cerutti, P.3


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