Genome-Wide Mutation Avalanches Induced in Diploid Yeast Cells by a Base Analog or an APOBEC Deaminase

PLoS Genetics

Volumn 9, Issue 9, 2013, Pages

  Lada, Artem G ^a   Stepchenkova, Elena I ^a,b,c   Waisertreiger, Irina S R ^a   Noskov, Vladimir N ^d   Dhar, Alok ^e   Eudy, James D ^e   Boissy, Robert J ^f   Hirano, Masayuki ^g   Rogozin, Igor B ^h   Pavlov, Youri I ^a,c  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b VAVILOV INSTITUTE OF GENERAL GENETICS   (Russian Federation)

^c ST PETERSBURG STATE UNIVERSITY   (Russian Federation)

^d J CRAIG VENTER INSTITUTE   (United States)

^e UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^f UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^g EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 N HYDROXYADENINE; CYTOSINE DEAMINASE; MUTAGENIC AGENT; PMCDA1 PROTEIN; PURINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL MUTANT; CELL SURVIVAL; CELL VIABILITY; CYTOTOXICITY; DIPLOIDY; ENZYME DEGRADATION; FUNGAL GENE; FUNGAL GENOME; FUNGAL STRAIN; FUNGAL VIABILITY; FUNGUS MUTANT; GENE INACTIVATION; GENE MUTATION; GENE OVEREXPRESSION; GENOMIC INSTABILITY; HAPLOIDY; HETEROZYGOSITY; INDUCED MUTATION; MUTATION RATE; NONHUMAN; NUCLEOTIDE METABOLISM; NUCLEOTIDE SEQUENCE; PMCDA1 GENE; PROGENY; REPORTER GENE; SACCHAROMYCES CEREVISIAE; YEAST CELL;

ADENINE; ANIMALS; CYTIDINE DEAMINASE; CYTOSINE DEAMINASE; DIPLOIDY; GENOME, FUNGAL; HAPLOIDY; HUMANS; LAMPREYS; MUTAGENESIS; MUTATION; MUTATION RATE; SACCHAROMYCES CEREVISIAE;

EID: 84884686754     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1003736     Document Type: Article

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