Genome destabilizing mutator alleles drive specific mutational trajectories in Saccharomyces cerevisiae

Genetics

Volumn 196, Issue 2, 2014, Pages 403-412

  Stirling, Peter C ^a,c   Shen, Yaoqing ^b   Corbett, Richard ^b   Jones, Steven J M ^b   Hieter, Philip ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b CANADA'S MICHAEL SMITH GENOME SCIENCES CENTRE   (Canada)

^c BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

Genome instability; High throughput sequencing; Mutation signature; Mutator; Yeast genome

Indexed keywords

ALLELE; ARTICLE; CLONAL VARIATION; ENVIRONMENTAL FACTOR; GENE MUTATION; GENE SEQUENCE; GENETIC STABILITY; GENOTYPE; MUTATOR GENE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PHENOTYPE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; TELOMERE; WILD TYPE;

GENOME INSTABILITY; HIGH-THROUGHPUT SEQUENCING; MUTATION SIGNATURE; MUTATOR; YEAST GENOME;

ALLELES; DNA COPY NUMBER VARIATIONS; GENES, ESSENTIAL; GENETIC LOCI; GENOME, FUNGAL; GENOMIC INSTABILITY; MUTATION; MUTATION RATE; RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE;

EID: 84901293540     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.113.159806     Document Type: Article

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