Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition

Genome Research

Volumn 24, Issue 11, 2014, Pages 1751-1764

  Lujan, Scott A ^a   Clausen, Anders R ^a   Clark, Alan B ^a   MacAlpine, Heather K ^b   MacAlpine, David M ^b   Malc, Ewa P ^c   Mieczkowski, Piotr A ^c   Burkholder, Adam B ^d   Fargo, David C ^d   Gordenin, Dmitry A ^a   Kunkel, Thomas A ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DNA REPLICATION ORIGIN; DNA REPLICATION TIMING; DNA SEQUENCE; GENE REPLICATION; GENE SEQUENCE; GENETIC CODE; GENETIC VARIABILITY; GENOMIC INSTABILITY; GERMLINE MUTATION; HETEROGENEOUS POLYMERASE FIDELITY; INDEL MUTATION; MISMATCH REPAIR; MOLECULAR GENETICS; NONHUMAN; NUCLEOSOME; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SPONTANEOUS MUTATION; ALGORITHM; BIOLOGICAL MODEL; DNA REPLICATION; ENZYMOLOGY; FUNGAL GENOME; GENETICS; METABOLISM; MOLECULAR EVOLUTION; MUTATION RATE;

DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE BETA; DNA DIRECTED DNA POLYMERASE GAMMA; NUCLEOSOME; SACCHAROMYCES CEREVISIAE PROTEIN;

ALGORITHMS; DNA MISMATCH REPAIR; DNA POLYMERASE I; DNA POLYMERASE II; DNA POLYMERASE III; DNA REPLICATION; EVOLUTION, MOLECULAR; GENETIC VARIATION; GENOME, FUNGAL; MODELS, GENETIC; MUTATION RATE; NUCLEOSOMES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ANALYSIS, DNA;

EID: 84923948943     PISSN: 10889051     EISSN: 15495469     Source Type: Journal    
DOI: 10.1101/gr.178335.114     Document Type: Article

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