-
1
-
-
21244503060
-
Interacting genetic loci cause airway hyperresponsiveness
-
Ackerman KG, Huang H, Grasemann H, Puma C, Singer JB, Hill AE, Lander E, Nadeau JH, Churchill GA, Drazen JM, et al. 2005. Interacting genetic loci cause airway hyperresponsiveness. Physiol Genomics 21: 105-111.
-
(2005)
Physiol Genomics
, vol.21
, pp. 105-111
-
-
Ackerman, K.G.1
Huang, H.2
Grasemann, H.3
Puma, C.4
Singer, J.B.5
Hill, A.E.6
Lander, E.7
Nadeau, J.H.8
Churchill, G.A.9
Drazen, J.M.10
-
2
-
-
84888389414
-
Evaluating empirical bounds on complex disease genetic architecture
-
Agarwala V, Flannick J, Sunyaev S, Altshuler D. 2013. Evaluating empirical bounds on complex disease genetic architecture. Nat Genet 45: 1418-1427.
-
(2013)
Nat Genet
, vol.45
, pp. 1418-1427
-
-
Agarwala, V.1
Flannick, J.2
Sunyaev, S.3
Altshuler, D.4
-
3
-
-
78149328425
-
Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses
-
Ahn SH, Deshmukh H, Johnson N, Cowell LG, Rude TH, Scott WK, Nelson CL, Zaas AK, Marchuk DA, Keum S, et al. 2010. Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses. PLoS Pathog 6: e1001088.
-
(2010)
PLoS Pathog
, vol.6
, pp. e1001088
-
-
Ahn, S.H.1
Deshmukh, H.2
Johnson, N.3
Cowell, L.G.4
Rude, T.H.5
Scott, W.K.6
Nelson, C.L.7
Zaas, A.K.8
Marchuk, D.A.9
Keum, S.10
-
4
-
-
84894354244
-
Genetic architecture of naturally occurring quantitative traits in plants: An updated synthesis
-
Alonso-Blanco C, Méndez-Vigo B. 2014. Genetic architecture of naturally occurring quantitative traits in plants: an updated synthesis. Curr Opin Plant Biol 18: 37-43.
-
(2014)
Curr Opin Plant Biol
, vol.18
, pp. 37-43
-
-
Alonso-Blanco, C.1
Méndez-Vigo, B.2
-
5
-
-
84884414964
-
Contribution of rare and common variants determine complex diseases-Hirschsprung disease as a model
-
Alves MM, Sribudiani Y, Brouwer RWW, Amiel J, Antiñolo G, Borrego S, Ceccherini I, Chakravarti A, Fernández RM, Garcia-Barcelo MM, et al. 2013. Contribution of rare and common variants determine complex diseases-Hirschsprung disease as a model. Dev Biol 382: 320-329.
-
(2013)
Dev Biol
, vol.382
, pp. 320-329
-
-
Alves, M.M.1
Sribudiani, Y.2
Rww, B.3
Amiel, J.4
Antiñolo, G.5
Borrego, S.6
Ceccherini, I.7
Chakravarti, A.8
Fernández, R.M.9
Garcia-Barcelo, M.M.10
-
6
-
-
84866420982
-
Systems genetics of metabolism: The use of the BXD murine reference panel for multisca-lar integration of traits
-
Andreux PA, Williams EG, Koutnikova H, Houtkooper RH, Champy MF, Henry H, Schoonjans K, Williams RW, Auwerx J. 2012. Systems genetics of metabolism: the use of the BXD murine reference panel for multisca-lar integration of traits. Cell 150: 1287-1299.
-
(2012)
Cell
, vol.150
, pp. 1287-1299
-
-
Andreux, P.A.1
Williams, E.G.2
Koutnikova, H.3
Houtkooper, R.H.4
Champy, M.F.5
Henry, H.6
Schoonjans, K.7
Williams, R.W.8
Auwerx, J.9
-
7
-
-
0029119781
-
Diversity of RET proto-on-cogene mutations in familial and sporadic Hirschsprung disease
-
Attié T, Pelet A, Edery P, Eng C, Mulligan LM, Amiel J, Boutrand L, Beldjord C, Nihoul-Fékété C, Munnich A, et al. 1995. Diversity of RET proto-on-cogene mutations in familial and sporadic Hirschsprung disease. Hum Mol Genet 4: 1381-1386.
-
(1995)
Hum Mol Genet
, vol.4
, pp. 1381-1386
-
-
Attié, T.1
Pelet, A.2
Edery, P.3
Eng, C.4
Mulligan, L.M.5
Amiel, J.6
Boutrand, L.7
Beldjord, C.8
Nihoul-Fékété, C.9
Munnich, A.10
-
8
-
-
79957658264
-
Genetic analysis of complex traits in the emerging Collaborative Cross
-
Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, Baric RS, Ferris MT, Frelinger JA, Heise M, Frieman MB, et al. 2011. Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res 21: 1213-1222.
-
(2011)
Genome Res
, vol.21
, pp. 1213-1222
-
-
Aylor, D.L.1
Valdar, W.2
Foulds-Mathes, W.3
Buus, R.J.4
Verdugo, R.A.5
Baric, R.S.6
Ferris, M.T.7
Frelinger, J.A.8
Heise, M.9
Frieman, M.B.10
-
9
-
-
84906825825
-
Genetic dissection of susceptibility genes for diabetes and related phenotypes on mouse chromosome 14 by means of congenic strains
-
Babaya N, Ueda H, Noso S, Hiromine Y, Itoi-Babaya M, Kobayashi M, Fujisawa T, Ikegami H. 2014. Genetic dissection of susceptibility genes for diabetes and related phenotypes on mouse chromosome 14 by means of congenic strains. BMC Genet 15: 93.
-
(2014)
BMC Genet
, vol.15
, pp. 93
-
-
Babaya, N.1
Ueda, H.2
Noso, S.3
Hiromine, Y.4
Itoi-Babaya, M.5
Kobayashi, M.6
Fujisawa, T.7
Ikegami, H.8
-
10
-
-
0041308085
-
Heterozygous mutations in BBS1, BBS2 and BBS6 have a potential epistatic effect on Bardet-Biedl patients with two mutations at a second BBS locus
-
Badano JL. 2003. Heterozygous mutations in BBS1, BBS2 and BBS6 have a potential epistatic effect on Bardet-Biedl patients with two mutations at a second BBS locus. Hum Mol Genet 12: 1651-1659.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 1651-1659
-
-
Badano, J.L.1
-
11
-
-
31144478298
-
Dissection of epistasis in oligo-genic Bardet-Biedl syndrome
-
Badano JL, Leitch CC, Ansley SJ, May-Simera H, Lawson S, Lewis RA, Beales PL, Dietz HC, Fisher S, Katsanis N. 2006. Dissection of epistasis in oligo-genic Bardet-Biedl syndrome. Nature 439: 326-330.
-
(2006)
Nature
, vol.439
, pp. 326-330
-
-
Badano, J.L.1
Leitch, C.C.2
Ansley, S.J.3
May-Simera, H.4
Lawson, S.5
Lewis, R.A.6
Beales, P.L.7
Dietz, H.C.8
Fisher, S.9
Katsanis, N.10
-
12
-
-
0015030096
-
Recombinant-inbred strains. An aid to finding identity, linkage, and function of histocompatibility and other genes
-
Bailey DW. 1971. Recombinant-inbred strains. An aid to finding identity, linkage, and function of histocompatibility and other genes. Transplantation 11: 325-327.
-
(1971)
Transplantation
, vol.11
, pp. 325-327
-
-
Bailey, D.W.1
-
13
-
-
33748804424
-
A tutorial on statistical methods for population association studies
-
Balding DJ. 2006. A tutorial on statistical methods for population association studies. Nat Rev Genet 7: 781-791.
-
(2006)
Nat Rev Genet
, vol.7
, pp. 781-791
-
-
Balding, D.J.1
-
14
-
-
0004255104
-
-
Springer, New York
-
Barnsley MF, Devaney RL, Mandelbrot BB, Peitgen HO, Saupe D, Voss RF. 1988. The science of fractal images. Springer, New York.
-
(1988)
The Science of Fractal Images
-
-
Barnsley, M.F.1
Devaney, R.L.2
Mandelbrot, B.B.3
Peitgen, H.O.4
Saupe, D.5
Voss, R.F.6
-
15
-
-
0038744241
-
Genetic interaction of BBS1 mutations with alleles at other BBS loci can result in non-Mendelian Bardet-Biedl syndrome
-
Beales PL, Badano JL, Ross AJ, Ansley SJ, Hoskins BE, Kirsten B, Mein CA, Froguel P, Scambler PJ, Lewis RA, et al. 2003. Genetic interaction of BBS1 mutations with alleles at other BBS loci can result in non-Mendelian Bardet-Biedl syndrome. Am J Hum Genet 72: 1187-1199.
-
(2003)
Am J Hum Genet
, vol.72
, pp. 1187-1199
-
-
Beales, P.L.1
Badano, J.L.2
Ross, A.J.3
Ansley, S.J.4
Hoskins, B.E.5
Kirsten, B.6
Mein, C.A.7
Froguel, P.8
Scambler, P.J.9
Lewis, R.A.10
-
16
-
-
0033989159
-
Genealogies of mouse inbred strains
-
Beck JA, Lloyd S, Hafezparast M, Lennon-Pierce M, Eppig JT, Festing MF, Fisher EM. 2000. Genealogies of mouse inbred strains. Nat Genet 24: 23-25.
-
(2000)
Nat Genet
, vol.24
, pp. 23-25
-
-
Beck, J.A.1
Lloyd, S.2
Hafezparast, M.3
Lennon-Pierce, M.4
Eppig, J.T.5
Festing, M.F.6
Fisher, E.M.7
-
17
-
-
0031914691
-
Effect of within-strain sample size on QTL detection and mapping using recombinant inbred mouse strains
-
Belknap JK. 1998. Effect of within-strain sample size on QTL detection and mapping using recombinant inbred mouse strains. Behav Genet 28: 29-38.
-
(1998)
Behav Genet
, vol.28
, pp. 29-38
-
-
Belknap, J.K.1
-
18
-
-
0242360752
-
Chromosome substitution strains: Some quantitative considerations for genome scans and fine mapping
-
Belknap JK. 2003. Chromosome substitution strains: some quantitative considerations for genome scans and fine mapping. Mamm Genome 14: 723-732.
-
(2003)
Mamm Genome
, vol.14
, pp. 723-732
-
-
Belknap, J.K.1
-
19
-
-
0027496447
-
Voluntary consumption of ethanol in 15 inbred mouse strains
-
Belknap JK, Crabbe JC, Young ER. 1993. Voluntary consumption of ethanol in 15 inbred mouse strains. Psychopharmacology 112: 503-510.
-
(1993)
Psychopharmacology
, vol.112
, pp. 503-510
-
-
Belknap, J.K.1
Crabbe, J.C.2
Young, E.R.3
-
20
-
-
77953309816
-
PCSK9 R46L, low-density lipoprotein cholesterol levels, and risk of is-chemic heart disease
-
Benn M, Nordestgaard BG, Grande P, Schnohr P, Tybjærg-Hansen A. 2010. PCSK9 R46L, low-density lipoprotein cholesterol levels, and risk of is-chemic heart disease. J Am Coll Cardiol 55: 2833-2842.
-
(2010)
J Am Coll Cardiol
, vol.55
, pp. 2833-2842
-
-
Benn, M.1
Nordestgaard, B.G.2
Grande, P.3
Schnohr, P.4
Tybjærg-Hansen, A.5
-
21
-
-
75649122259
-
A high-resolution association mapping panel for the dissection of complex traits in mice
-
Bennett BJ, Farber CR, Orozco L, Min Kang H, Ghazalpour A, Siemers N, Neubauer M, Neuhaus I, Yordanova R, Guan B, et al. 2010. A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Res 20: 281-290.
-
(2010)
Genome Res
, vol.20
, pp. 281-290
-
-
Bennett, B.J.1
Farber, C.R.2
Orozco, L.3
Min Kang, H.4
Ghazalpour, A.5
Siemers, N.6
Neubauer, M.7
Neuhaus, I.8
Yordanova, R.9
Guan, B.10
-
22
-
-
84872139636
-
Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation
-
Bennett BJ, de Aguiar Vallim TQ, Wang Z, Shih DM, Meng Y, Gregory J, Allayee H, Lee R, Graham M, Crooke R, et al. 2013. Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation. Cell Metab 17: 49-60.
-
(2013)
Cell Metab
, vol.17
, pp. 49-60
-
-
Bennett, B.J.1
De Aguiar Vallim, T.Q.2
Wang, Z.3
Shih, D.M.4
Meng, Y.5
Gregory, J.6
Allayee, H.7
Lee, R.8
Graham, M.9
Crooke, R.10
-
23
-
-
80055076208
-
Positional cloning ofatype 2 diabetes quantitative trait locus; Tomosyn-2, a negative regulator of insulin secretion
-
Bhatnagar S, Oler AT, Rabaglia ME, Stapleton DS, Schueler KL, Truchan NA, Worzella SL, Stoehr JP, Clee SM, Yandell BS, et al. 2011. Positional cloning ofatype 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion. PLoS Genet 7: e1002323.
-
(2011)
PLoS Genet
, vol.7
, pp. e1002323
-
-
Bhatnagar, S.1
Oler, A.T.2
Rabaglia, M.E.3
Stapleton, D.S.4
Schueler, K.L.5
Truchan, N.A.6
Worzella, S.L.7
Stoehr, J.P.8
Clee, S.M.9
Yandell, B.S.10
-
24
-
-
0031756060
-
Differential effects of fat and sucrose on body composition in A/J and C57BL/6 mice
-
Black BL, Croom J, Eisen EJ, Petro AE, Edwards CL, Surwit RS. 1998. Differential effects of fat and sucrose on body composition in A/J and C57BL/6 mice. Metabolism 47: 1354-1359.
-
(1998)
Metabolism
, vol.47
, pp. 1354-1359
-
-
Black, B.L.1
Croom, J.2
Eisen, E.J.3
Petro, A.E.4
Edwards, C.L.5
Surwit, R.S.6
-
25
-
-
84873722165
-
Finding the sources of missing heritability in a yeast cross
-
Bloom JS, Ehrenreich IM, Loo WT, Lite TL, Kruglyak L. 2013. Finding the sources of missing heritability in a yeast cross. Nature 494: 234-237.
-
(2013)
Nature
, vol.494
, pp. 234-237
-
-
Bloom, J.S.1
Ehrenreich, I.M.2
Loo, W.T.3
Lite, T.L.4
Kruglyak, L.5
-
26
-
-
80054123171
-
A comparative assessment of mandible shape in a consomic strain panel of the house mouse (Mus musculus)-implications for epistasis and evolvability of quantitative traits
-
Boell L, Gregorova S, Forejt J, Tautz D. 2011. A comparative assessment of mandible shape in a consomic strain panel of the house mouse (Mus musculus)-implications for epistasis and evolvability of quantitative traits. BMC Evol Biol 11: 309.
-
(2011)
BMC Evol Biol
, vol.11
, pp. 309
-
-
Boell, L.1
Gregorova, S.2
Forejt, J.3
Tautz, D.4
-
27
-
-
57149139136
-
Confirmation of provisional quantitative trait loci for voluntary alcohol consumption: Genetic analysis in chromosome substitution strains and F2 crosses derived from A/J and C57BL/6J progenitors
-
Boyle AE, Gill KJ. 2008. Confirmation of provisional quantitative trait loci for voluntary alcohol consumption: genetic analysis in chromosome substitution strains and F2 crosses derived from A/J and C57BL/6J progenitors. Pharmacogenet Genomics 18: 1071-1082.
-
(2008)
Pharmacogenet Genomics
, vol.18
, pp. 1071-1082
-
-
Boyle, A.E.1
Gill, K.J.2
-
28
-
-
58649117562
-
Genetic analysis of the psychostimulant effects of nicotine in chromosome substitution strains and F2 crosses derived from A/J and C57BL/6J progenitors
-
Boyle AE, Gill KJ. 2009. Genetic analysis of the psychostimulant effects of nicotine in chromosome substitution strains and F2 crosses derived from A/J and C57BL/6J progenitors. Mamm Genome 20: 34-42.
-
(2009)
Mamm Genome
, vol.20
, pp. 34-42
-
-
Boyle, A.E.1
Gill, K.J.2
-
29
-
-
84867332476
-
The mammalian gene function resource: The International Knockout Mouse Consortium
-
Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bürger A, Bult CJ, et al. 2012. The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome 23: 580-586.
-
(2012)
Mamm Genome
, vol.23
, pp. 580-586
-
-
Bradley, A.1
Anastassiadis, K.2
Ayadi, A.3
Battey, J.F.4
Bell, C.5
Birling, M.C.6
Bottomley, J.7
Brown, S.D.8
Bürger, A.9
Bult, C.J.10
-
30
-
-
84867337003
-
The International Mouse Phenotyping Consortium: Past and future perspectives on mouse phenotyping
-
Brown SDM, Moore MW. 2012. The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping. Mamm Genome 23: 632-640.
-
(2012)
Mamm Genome
, vol.23
, pp. 632-640
-
-
Sdm, B.1
Moore, M.W.2
-
31
-
-
84899627083
-
Genetic interactions affecting human gene expression identified by variance association mapping
-
Brown AA, Buil A, Viñuela A, Lappalainen T, Zheng HF, Richards JB, Small KS, Spector TD, Dermitzakis ET, Durbin R. 2014. Genetic interactions affecting human gene expression identified by variance association mapping. Elife 3: e01381.
-
(2014)
Elife
, vol.3
, pp. e01381
-
-
Brown, A.A.1
Buil, A.2
Viñuela, A.3
Lappalainen, T.4
Zheng, H.F.5
Richards, J.B.6
Small, K.S.7
Spector, T.D.8
Dermitzakis, E.T.9
Durbin, R.10
-
32
-
-
0043244855
-
SCNM1, a putative RNA splicing factor that modifies disease severity in mice
-
Buchner DA, Trudeau M, MeislerMH. 2003. SCNM1, a putative RNA splicing factor that modifies disease severity in mice. Science 301: 967-969.
-
(2003)
Science
, vol.301
, pp. 967-969
-
-
Buchner, D.A.1
Trudeau, M.2
Meislermh3
-
33
-
-
84865135133
-
The juxta-paranodal proteins CNTNAP2 and TAG1 regulate diet-induced obesity
-
Buchner DA, Geisinger JM, Glazebrook PA, Morgan MG, Spiezio SH, Kaiyala KJ, Schwartz MW, Sakurai T, Furley AJ, Kunze DL, et al. 2012. The juxta-paranodal proteins CNTNAP2 and TAG1 regulate diet-induced obesity. Mamm Genome 23: 431-442.
-
(2012)
Mamm Genome
, vol.23
, pp. 431-442
-
-
Buchner, D.A.1
Geisinger, J.M.2
Glazebrook, P.A.3
Morgan, M.G.4
Spiezio, S.H.5
Kaiyala, K.J.6
Schwartz, M.W.7
Sakurai, T.8
Furley, A.J.9
Kunze, D.L.10
-
34
-
-
77952430319
-
Genetic resistance to diet-induced obesity in chromosome substitution strains of mice
-
Burrage L, Baskin-Hill A, Sinasac D, Singer J, Croniger C, Kirby A, Kulbokas E, Daly M, Lander E, Broman K, et al. 2010. Genetic resistance to diet-induced obesity in chromosome substitution strains of mice. Mamm Genome 21: 115-129.
-
(2010)
Mamm Genome
, vol.21
, pp. 115-129
-
-
Burrage, L.1
Baskin-Hill, A.2
Sinasac, D.3
Singer, J.4
Croniger, C.5
Kirby, A.6
Kulbokas, E.7
Daly, M.8
Lander, E.9
Broman, K.10
-
35
-
-
20144383240
-
Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics
-
Bystrykh L, Weersing E, Dontje B, Sutton S, Pletcher MT, Wiltshire T, Su AI, Vellenga E, WangJ, Manly KF, et al. 2005. Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics.' Nat Genet 37: 225-232.
-
(2005)
Nat Genet
, vol.37
, pp. 225-232
-
-
Bystrykh, L.1
Weersing, E.2
Dontje, B.3
Sutton, S.4
Pletcher, M.T.5
Wiltshire, T.6
Su, A.I.7
Vellenga, E.8
Wangj Manly, K.F.9
-
36
-
-
84884892198
-
Distilling pathophysiology from complex disease genetics
-
Chakravarti A, Clark AG, Mootha VK. 2013. Distilling pathophysiology from complex disease genetics. Cell 155: 21-26.
-
(2013)
Cell
, vol.155
, pp. 21-26
-
-
Chakravarti, A.1
Clark, A.G.2
Mootha, V.K.3
-
37
-
-
84878497749
-
Human monogenic disease genes have frequently functionally redundant paralogs
-
Chen WH, Zhao XM, van Noort V, Bork P. 2013. Human monogenic disease genes have frequently functionally redundant paralogs. PLoS Comput Biol 9: e1003073.
-
(2013)
PLoS Comput Biol
, vol.9
, pp. e1003073
-
-
Chen, W.H.1
Zhao, X.M.2
Van Noort, V.3
Bork, P.4
-
38
-
-
27644551418
-
The origins and uses of mouse outbred stocks
-
Chia R, Achilli F, Festing MFW, Fisher EMC. 2005. The origins and uses of mouse outbred stocks. Nat Genet 37: 1181-1186.
-
(2005)
Nat Genet
, vol.37
, pp. 1181-1186
-
-
Chia, R.1
Achilli, F.2
Mfw, F.3
Fisher, E.M.C.4
-
39
-
-
14644441018
-
The Collaborative Cross, a community resource for the genetic analysis of complex traits
-
Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, et al. 2004. The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat Genet 36: 1133-1137.
-
(2004)
Nat Genet
, vol.36
, pp. 1133-1137
-
-
Churchill, G.A.1
Airey, D.C.2
Allayee, H.3
Angel, J.M.4
Attie, A.D.5
Beatty, J.6
Beavis, W.D.7
Belknap, J.K.8
Bennett, B.9
Berrettini, W.10
-
41
-
-
84890546613
-
Systems genetics approaches to understand complex traits
-
CivelekM, Lusis AJ. 2014. Systems genetics approaches to understand complex traits. Nat Rev Genet 15: 34-48.
-
(2014)
Nat Rev Genet
, vol.15
, pp. 34-48
-
-
Civelekm Lusis, A.J.1
-
42
-
-
84893351797
-
Policy: NIH plans to enhance reproducibility
-
Collins FS, Tabak LA. 2014. Policy: NIH plans to enhance reproducibility. Nature 505: 612-613.
-
(2014)
Nature
, vol.505
, pp. 612-613
-
-
Collins, F.S.1
Tabak, L.A.2
-
43
-
-
77951468653
-
The Gene Environment Association Studies consortium (GENEVA): Maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions
-
Cornelis MC, Agrawal A, Cole JW, Hansel NN, Barnes KC, Beaty TH, Bennett SN, Bierut LJ, Boerwinkle E, Doheny KF, et al. 2010. The Gene, Environment Association Studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions. Genet Epidemiol 34: 364-372.
-
(2010)
Genet Epidemiol
, vol.34
, pp. 364-372
-
-
Cornelis, M.C.1
Agrawal, A.2
Cole, J.W.3
Hansel, N.N.4
Barnes, K.C.5
Beaty, T.H.6
Bennett, S.N.7
Bierut, L.J.8
Boerwinkle, E.9
Doheny, K.F.10
-
44
-
-
84895791699
-
Lipin-1 andlipin-3 together determine adiposity in vivo
-
Csaki LS, Dwyer JR, Li X, Nguyen MHK, Dewald J, Brindley DN, Lusis AJ, YoshinagaY, deJongP, FongL, et al. 2014. Lipin-1 andlipin-3 together determine adiposity in vivo. Mol Metab 3: 145-154.
-
(2014)
Mol Metab
, vol.3
, pp. 145-154
-
-
Csaki, L.S.1
Dwyer, J.R.2
Li, X.3
Mhk, N.4
Dewald, J.5
Brindley, D.N.6
Lusis, A.J.7
Yoshinaga, Y.8
Dejong, P.9
Fong, L.10
-
45
-
-
84925351969
-
Lipid lowering with PCSK9 inhibitors
-
Dadu RT, Ballantyne CM. 2014. Lipid lowering with PCSK9 inhibitors. Nat Rev Cardiol 11: 563-575.
-
(2014)
Nat Rev Cardiol
, vol.11
, pp. 563-575
-
-
Dadu, R.T.1
Ballantyne, C.M.2
-
46
-
-
84877809305
-
Genome-wide association mapping of blood cell traits in mice
-
Davis RC, Nas A, Bennett B, Orozco L, Pan C, Rau CD, Eskin E, Lusis AJ. 2013. Genome-wide association mapping of blood cell traits in mice. Mamm Genome 24: 105-118.
-
(2013)
Mamm Genome
, vol.24
, pp. 105-118
-
-
Davis, R.C.1
Nas, A.2
Bennett, B.3
Orozco, L.4
Pan, C.5
Rau, C.D.6
Eskin, E.7
Lusis, A.J.8
-
47
-
-
79958137528
-
Hippo-campal gene expression analysis highlights Ly6a/Sca-1 as candidate gene for previously mapped novelty induced behaviors in mice
-
De Jong S, Kas MJH, Kiernan J, de Mooij-van Malsen AG, Oppelaar H, Janson E, Vukobradovic I, Farber CR, Stanford WL, Ophoff RA. 2011. Hippo-campal gene expression analysis highlights Ly6a/Sca-1 as candidate gene for previously mapped novelty induced behaviors in mice. PLoS One 6: e20716.
-
(2011)
PLoS One
, vol.6
, pp. e20716
-
-
De Jong, S.1
Mjh, K.2
Kiernan, J.3
De Mooij-Van Malsen, A.G.4
Oppelaar, H.5
Janson, E.6
Vukobradovic, I.7
Farber, C.R.8
Stanford, W.L.9
Ophoff, R.A.10
-
48
-
-
70549108065
-
Interspecies trait genetics reveals association ofAdcy8 with mouse avoidance behavior and a human mood disorder
-
De Mooij-van Malsen AJ, van Lith HA, Oppelaar H, Hendriks J, de Wit M, Kostrzewa E, Breen G, Collier DA, Olivier B, Kas MJ. 2009. Interspecies trait genetics reveals association ofAdcy8 with mouse avoidance behavior and a human mood disorder. Biol Psychiatry 66: 1123-1130.
-
(2009)
Biol Psychiatry
, vol.66
, pp. 1123-1130
-
-
De Mooij-Van Malsen, A.J.1
Van Lith, H.A.2
Oppelaar, H.3
Hendriks, J.4
De Wit, M.5
Kostrzewa, E.6
Breen, G.7
Collier, D.A.8
Olivier, B.9
Kas, M.J.10
-
49
-
-
84881100967
-
Cross-species genetics converge to TLL2 for mouse avoidance behavior and human bipolar disorder: Additional mouse avoidance QTL linked to bipolar disorder
-
De Mooij-van Malsen JG, van Lith HA, Laarakker MC, Brandys MK, Oppelaar H, Collier DA, Olivier B, Breen G, Kas MJ. 2013. Cross-species genetics converge to TLL2 for mouse avoidance behavior and human bipolar disorder: additional mouse avoidance QTL linked to bipolar disorder. Genes Brain Behav 12: 653-657.
-
(2013)
Genes Brain Behav
, vol.12
, pp. 653-657
-
-
De Mooij-Van Malsen, J.G.1
Van Lith, H.A.2
Laarakker, M.C.3
Brandys, M.K.4
Oppelaar, H.5
Collier, D.A.6
Olivier, B.7
Breen, G.8
Kas, M.J.9
-
50
-
-
84884975459
-
Genetic resistance to liver fibrosis on A/J mouse chromosome 17
-
DeSantis DA, Lee P, Doerner SK, Ko CW, Kawasoe JH, Hill-Baskin AE, Ernest SR, Bhargava P, Hur KY, Cresci GA, et al. 2013. Genetic resistance to liver fibrosis on A/J mouse chromosome 17. Alcohol Clin Exp Res 37: 1668-1679.
-
(2013)
Alcohol Clin Exp Res
, vol.37
, pp. 1668-1679
-
-
Desantis, D.A.1
Lee, P.2
Doerner, S.K.3
Ko, C.W.4
Kawasoe, J.H.5
Hill-Baskin, A.E.6
Ernest, S.R.7
Bhargava, P.8
Hur, K.Y.9
Cresci, G.A.10
-
51
-
-
84908068927
-
SNP array profilingof mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy
-
Didion JP, Buus RJ, Naghashfar Z, Threadgill DW, Morse HC III, de Villena FP. 2014. SNP array profilingof mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy. BMC Genomics 15: 847.
-
(2014)
BMC Genomics
, vol.15
, pp. 847
-
-
Didion, J.P.1
Buus, R.J.2
Naghashfar, Z.3
Threadgill, D.W.4
Morse, H.C.5
De Villena, F.P.6
-
52
-
-
84866946846
-
The long path from QTL to gene
-
Drinkwater NR, Gould MN. 2012. The long path from QTL to gene. PLoS Genet 8: e1002975.
-
(2012)
PLoS Genet
, vol.8
, pp. e1002975
-
-
Drinkwater, N.R.1
Gould, M.N.2
-
53
-
-
84900006125
-
Epigenetics, plasticity, and evolution: How do we link epigenetic change to phenotype?
-
Duncan EJ, Gluckman PD, Dearden PK. 2014. Epigenetics, plasticity, and evolution: how do we link epigenetic change to phenotype? J Exp Zool B Mol Dev Evol 322: 208-220.
-
(2014)
J Exp Zool B Mol Dev Evol
, vol.322
, pp. 208-220
-
-
Duncan, E.J.1
Gluckman, P.D.2
Dearden, P.K.3
-
54
-
-
80051556204
-
Collaborative Cross mice and their power to map host susceptibility to Aspergillus fumigatus infection
-
Durrant C, Tayem H, Yalcin B, Cleak J, Goodstadt L, de Villena FP, Mott R, Iraqi FA. 2011. Collaborative Cross mice and their power to map host susceptibility to Aspergillus fumigatus infection. Genome Res 21: 1239-1248.
-
(2011)
Genome Res
, vol.21
, pp. 1239-1248
-
-
Durrant, C.1
Tayem, H.2
Yalcin, B.3
Cleak, J.4
Goodstadt, L.5
De Villena, F.P.6
Mott, R.7
Iraqi, F.A.8
-
55
-
-
80053907554
-
Genetic variants innovel pathways influence blood pressure and cardiovascular disease risk
-
Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, et al. 2011. Genetic variants innovel pathways influence blood pressure and cardiovascular disease risk. Nature 478: 103-109.
-
(2011)
Nature
, vol.478
, pp. 103-109
-
-
Ehret, G.B.1
Munroe, P.B.2
Rice, K.M.3
Bochud, M.4
Johnson, A.D.5
Chasman, D.I.6
Smith, A.V.7
Tobin, M.D.8
Verwoert, G.C.9
Hwang, S.J.10
-
56
-
-
84868369445
-
A multi-SNP locus-association method reveals a substantial fraction of the missing heritability
-
Genetic Investigation of Anthropomet-ric Traits Consortium, Whittaker JC, Beckmann JS, Kutalik Z.
-
Ehret GB, Lamparter D, Hoggart CJ, Genetic Investigation of Anthropomet-ric Traits Consortium, Whittaker JC, Beckmann JS, Kutalik Z. 2012. A multi-SNP locus-association method reveals a substantial fraction of the missing heritability. Am J Hum Genet 91: 863-871.
-
(2012)
Am J Hum Genet
, vol.91
, pp. 863-871
-
-
Ehret, G.B.1
Lamparter, D.2
Hoggart, C.J.3
-
57
-
-
77952557918
-
Missing heritability and strategies for finding the underlying causes of complex disease
-
Eichler EE, Flint J, Gibson G, Kong A, Leal SM, Moore JH, Nadeau JH. 2010. Missing heritability and strategies for finding the underlying causes of complex disease. Nat Rev Genet 11: 446-450.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 446-450
-
-
Eichler, E.E.1
Flint, J.2
Gibson, G.3
Kong, A.4
Leal, S.M.5
Moore, J.H.6
Nadeau, J.H.7
-
58
-
-
79955638043
-
Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis
-
Farber CR, Bennett BJ, OrozcoL, ZouW, LiraA, KostemE, Kang HM, Furlotte N, Berberyan A, Ghazalpour A, et al. 2011. Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis. PLoS Genet 7: e1002038.
-
(2011)
PLoS Genet
, vol.7
, pp. e1002038
-
-
Farber, C.R.1
Bennett, B.J.2
Zouw, O.3
Kosteme, L.4
Kang, H.M.5
Furlotte, N.6
Berberyan, A.7
Ghazalpour, A.8
-
59
-
-
84930088305
-
Melanoma susceptibility as a complex trait: Genetic variation controls all stages of tumor progression
-
Ferguson B, Ram R, Handoko HY, Mukhopadhyay P, Muller HK, Soyer HP, Morahan G, Walker GJ. 2014. Melanoma susceptibility as a complex trait: genetic variation controls all stages of tumor progression. Oncogene doi: 10.1038/onc.2014.227.
-
(2014)
Oncogene
-
-
Ferguson, B.1
Ram, R.2
Handoko, H.Y.3
Mukhopadhyay, P.4
Muller, H.K.5
Soyer, H.P.6
Morahan, G.7
Walker, G.J.8
-
60
-
-
84880944577
-
Modeling host genetic regulation of influenza pathogenesis in the collaborative cross
-
Ferris MT, Aylor DL, Bottomly D, Whitmore AC, Aicher LD, Bell TA, Bradel-Tretheway B, Bryan JT, Buus RJ, Gralinski LE, et al. 2013. Modeling host genetic regulation of influenza pathogenesis in the collaborative cross. PLoS Pathog 9: e1003196.
-
(2013)
PLoS Pathog
, vol.9
, pp. e1003196
-
-
Ferris, M.T.1
Aylor, D.L.2
Bottomly, D.3
Whitmore, A.C.4
Aicher, L.D.5
Bell, T.A.6
Bradel-Tretheway, B.7
Bryan, J.T.8
Buus, R.J.9
Gralinski, L.E.10
-
61
-
-
15944376562
-
Strategies for mapping and cloning quantitative trait genes in rodents
-
Flint J, Valdar W, Shifman S, Mott R. 2005. Strategies for mapping and cloning quantitative trait genes in rodents. Nat Rev Genet 6: 271-286.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 271-286
-
-
Flint, J.1
Valdar, W.2
Shifman, S.3
Mott, R.4
-
62
-
-
84888132259
-
Identifying multiple causative genes at a single GWAS locus
-
Flister MJ, Tsaih SW, O'Meara CC, Endres B, Hoffman MJ, Geurts AM, Dwinell MR, Lazar J, Jacob HJ, Moreno C. 2013. Identifying multiple causative genes at a single GWAS locus. Genome Res 23: 1996-2002.
-
(2013)
Genome Res
, vol.23
, pp. 1996-2002
-
-
Flister, M.J.1
Tsaih, S.W.2
O'Meara, C.C.3
Endres, B.4
Hoffman, M.J.5
Geurts, A.M.6
Dwinell, M.R.7
Lazar, J.8
Jacob, H.J.9
Moreno, C.10
-
63
-
-
0242361316
-
A natural allele of Nxf1 suppresses retrovirus insertional mutations
-
Floyd JA, Gold DA, Concepcion D, Poon TH, Wang X, Keithley E, Chen D, Ward EJ, Chinn SB, Friedman RA, et al. 2003. A natural allele of Nxf1 suppresses retrovirus insertional mutations. Nat Genet 35: 221-228.
-
(2003)
Nat Genet
, vol.35
, pp. 221-228
-
-
Floyd, J.A.1
Gold, D.A.2
Concepcion, D.3
Poon, T.H.4
Wang, X.5
Keithley, E.6
Chen, D.7
Ward, E.J.8
Chinn, S.B.9
Friedman, R.A.10
-
65
-
-
79957639316
-
Architecture of energy balance traits in emerging lines of the Collaborative Cross
-
Foulds Mathes W, Aylor DL, Miller DR, Churchill GA, Chesler EJ, de Villena FP, Threadgill DW, Pomp D. 2011. Architecture of energy balance traits in emerging lines of the Collaborative Cross. Am J Physiol Endocrinol Metab 300: E1124-E1134.
-
(2011)
Am J Physiol Endocrinol Metab
, vol.300
, pp. E1124-E1134
-
-
Foulds Mathes, W.1
Aylor, D.L.2
Miller, D.R.3
Churchill, G.A.4
Chesler, E.J.5
De Villena, F.P.6
Threadgill, D.W.7
Pomp, D.8
-
66
-
-
84875706378
-
Seven new loci associated with age-related macular degeneration
-
Fritsche LG, Chen W, Schu M, Yaspan BL, Yu Y, Thorleifsson G, Zack DJ, Arakawa S, Cipriani V, Ripke S, et al. 2013. Seven new loci associated with age-related macular degeneration. Nat Genet 45: 433-439.
-
(2013)
Nat Genet
, vol.45
, pp. 433-439
-
-
Fritsche, L.G.1
Chen, W.2
Schu, M.3
Yaspan, B.L.4
Yu, Y.5
Thorleifsson, G.6
Zack, D.J.7
Arakawa, S.8
Cipriani, V.9
Ripke, S.10
-
67
-
-
18544365991
-
Segregation at three loci explains familial and population risk in Hirschsprung disease
-
Gabriel SB, Salomon R, Pelet A, Angrist M, Amiel J, Fornage M, Attié-Bitach T, Olson JM, Hofstra R, Buys C, et al. 2002. Segregation at three loci explains familial and population risk in Hirschsprung disease. Nat Genet 31: 89-93.
-
(2002)
Nat Genet
, vol.31
, pp. 89-93
-
-
Gabriel, S.B.1
Salomon, R.2
Pelet, A.3
Angrist, M.4
Amiel, J.5
Fornage, M.6
Attié-Bitach, T.7
Olson, J.M.8
Hofstra, R.9
Buys, C.10
-
68
-
-
84879264708
-
ZFN TALEN and CRISPR/Cas-based methods for genome engineering
-
Gaj T, Gersbach CA, Barbas CF III. 2013. ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends Biotechnol 31: 397-405.
-
(2013)
Trends Biotechnol
, vol.31
, pp. 397-405
-
-
Gaj, T.1
Gersbach, C.A.2
Barbas, C.F.3
-
69
-
-
78649469071
-
Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation
-
Galarneau G, Palmer CD, Sankaran VG, Orkin SH, Hirschhorn JN, Lettre G. 2010. Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation. Nat Genet 42: 1049-1051.
-
(2010)
Nat Genet
, vol.42
, pp. 1049-1051
-
-
Galarneau, G.1
Palmer, C.D.2
Sankaran, V.G.3
Orkin, S.H.4
Hirschhorn, J.N.5
Lettre, G.6
-
70
-
-
62449175742
-
Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease
-
Garcia-Barcelo MM, Tang CS, Ngan ES, Lui VC, Chen Y, So MT, Leon TYY, Miao XP, Shum CK, Liu FQ, et al. 2009. Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease. Proc Natl Acad Sci 106: 2694-2699.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 2694-2699
-
-
Garcia-Barcelo, M.M.1
Tang, C.S.2
Ngan, E.S.3
Lui, V.C.4
Chen, Y.5
So, M.T.6
Tyy, L.7
Miao, X.P.8
Shum, C.K.9
Liu, F.Q.10
-
71
-
-
84907911617
-
Quantitative trait locus mapping methods for diversity outbred mice
-
Gatti DM, Svenson KL, Shabalin A, Wu LY, Valdar W, Simecek P, Goodwin N, Cheng R, Pomp D, Palmer A, et al. 2014. Quantitative trait locus mapping methods for diversity outbred mice. G3 (Bethesda) 4: 1623-1633.
-
(2014)
G3 (Bethesda)
, vol.4
, pp. 1623-1633
-
-
Gatti, D.M.1
Svenson, K.L.2
Shabalin, A.3
Wu, L.Y.4
Valdar, W.5
Simecek, P.6
Goodwin, N.7
Cheng, R.8
Pomp, D.9
Palmer, A.10
-
72
-
-
84867332713
-
Hybrid mouse diversity panel: A panel of inbred mouse strains suitable for analysis of complex genetic traits
-
Ghazalpour A, Rau CD, Farber CR, Bennett BJ, Orozco LD, Nas A, Pan C, Allayee H, Beaven SW, Civelek M, et al. 2012. Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mamm Genome 23: 680-692.
-
(2012)
Mamm Genome
, vol.23
, pp. 680-692
-
-
Ghazalpour, A.1
Rau, C.D.2
Farber, C.R.3
Bennett, B.J.4
Orozco, L.D.5
Nas, A.6
Pan, C.7
Allayee, H.8
Beaven, S.W.9
Civelek, M.10
-
73
-
-
84901640509
-
Genetic regulation of mouse liver metabolite levels
-
Ghazalpour A, Bennett BJ, Shih D, Che N, Orozco L, Pan C, Hagopian R, He A, Kayne P, Yang WP, et al. 2014. Genetic regulation of mouse liver metabolite levels. Mol Syst Biol 10: 730-730.
-
(2014)
Mol Syst Biol
, vol.10
, pp. 730-730
-
-
Ghazalpour, A.1
Bennett, B.J.2
Shih, D.3
Che, N.4
Orozco, L.5
Pan, C.6
Hagopian, R.7
He, A.8
Kayne, P.9
Yang, W.P.10
-
74
-
-
0017181444
-
Mouse haemoglobin β chains. Comparative sequence data on adult major and minor β chains from two species, Mus musculus and Mus cervicolor
-
Gilman JG. 1976. Mouse haemoglobin β chains. Comparative sequence data on adult major and minor β chains from two species, Mus musculus and Mus cervicolor. Biochem J 159: 43-53.
-
(1976)
Biochem J
, vol.159
, pp. 43-53
-
-
Gilman, J.G.1
-
75
-
-
80053486081
-
Genetics and genomics to the clinic: A long road ahead
-
Ginsburg D. 2011. Genetics and genomics to the clinic: a long road ahead. Cell 147: 17-19.
-
(2011)
Cell
, vol.147
, pp. 17-19
-
-
Ginsburg, D.1
-
76
-
-
0037146578
-
Finding genes that underlie complex traits
-
Glazier AM, Nadeau JH, Aitman TJ. 2002. Finding genes that underlie complex traits. Science 298: 2345-2349.
-
(2002)
Science
, vol.298
, pp. 2345-2349
-
-
Glazier, A.M.1
Nadeau, J.H.2
Aitman, T.J.3
-
77
-
-
84857408446
-
Varying coefficient models for mapping quantitative trait loci using recombinant inbred intercrosses
-
Gong Y, Zou F. 2012. Varying coefficient models for mapping quantitative trait loci using recombinant inbred intercrosses. Genetics 190: 475-486.
-
(2012)
Genetics
, vol.190
, pp. 475-486
-
-
Gong, Y.1
Zou, F.2
-
78
-
-
84868087341
-
Cofilin-1:amodulatorofanxietyinmice
-
Goodson M, Rust MB, Witke W, Bannerman D, Mott R, Ponting CP, Flint J. 2012. Cofilin-1:amodulatorofanxietyinmice. PLoS Genet8:e1002970.
-
(2012)
PLoS Genet
, vol.8
, pp. e1002970
-
-
Goodson, M.1
Rust, M.B.2
Witke, W.3
Bannerman, D.4
Mott, R.5
Ponting, C.P.6
Flint, J.7
-
79
-
-
40449084149
-
Mouse consomic strains: Exploiting genetic divergence between Mus m. Musculus and Mus m. Domesticus subspecies
-
Gregorová S, Divina P, Storchova R, Trachtulec Z, Fotopulosova V, Svenson KL, Donahue LR, Paigen B, Forejt J. 2008. Mouse consomic strains: exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies. Genome Res 18: 509-515.
-
(2008)
Genome Res
, vol.18
, pp. 509-515
-
-
Gregorová, S.1
Divina, P.2
Storchova, R.3
Trachtulec, Z.4
Fotopulosova, V.5
Svenson, K.L.6
Donahue, L.R.7
Paigen, B.8
Forejt, J.9
-
80
-
-
78650119765
-
The retinoic acid receptor β (Rarb) region of Mmu14 is associated with prion disease incubation time in mouse
-
Grizenkova J, Akhtar S, Collinge J, Lloyd SE. 2010. The retinoic acid receptor β (Rarb) region of Mmu14 is associated with prion disease incubation time in mouse. PLoS One 5: e15019.
-
(2010)
PLoS One
, vol.5
, pp. e15019
-
-
Grizenkova, J.1
Akhtar, S.2
Collinge, J.3
Lloyd, S.E.4
-
81
-
-
84874175265
-
Transgenerational epigenetic inheritance: How important is it?
-
Grossniklaus U, Kelly B, Ferguson-Smith AC, Pembrey M, Lindquist S. 2013. Transgenerational epigenetic inheritance: how important is it? Nat Rev Genet 14: 228-235.
-
(2013)
Nat Rev Genet
, vol.14
, pp. 228-235
-
-
Grossniklaus, U.1
Kelly, B.2
Ferguson-Smith, A.C.3
Pembrey, M.4
Lindquist, S.5
-
83
-
-
84901335706
-
Comparative genome-wide association studies in mice and humans for trimethylamine N-oxide a proatherogenic metabolite of cho-line and L-carnitine
-
Hartiala J, Bennett BJ, Tang WH, Wang Z, Stewart AFR, Roberts R, McPherson R, Lusis AJ, Hazen SL; CARDIoGRAM Consortium, et al. 2014. Comparative genome-wide association studies in mice and humans for trimethylamine N-oxide, a proatherogenic metabolite of cho-line and L-carnitine. Arterioscler Thromb Vasc Biol 34: 1307-1313.
-
(2014)
Arterioscler Thromb Vasc Biol
, vol.34
, pp. 1307-1313
-
-
Hartiala, J.1
Bennett, B.J.2
Tang, W.H.3
Wang, Z.4
Afr, S.5
Roberts, R.6
McPherson, R.7
Lusis, A.J.8
Hazen, S.L.9
Consortium Et Al., C.10
-
84
-
-
84897139220
-
Transgenerational epigenetic inheritance: Myths and mechanisms
-
Heard E, Martienssen RA. 2014. Transgenerational epigenetic inheritance: myths and mechanisms. Cell 157: 95-109.
-
(2014)
Cell
, vol.157
, pp. 95-109
-
-
Heard, E.1
Martienssen, R.A.2
-
85
-
-
84900302836
-
Detection and replication of epistasis influencing transcription in humans
-
Hemani G, ShakhbazovK, Westra HJ, EskoT, Henders AK, McRae AF, Yang J, GibsonG, Martin NG, MetspaluA, et al. 2014. Detection and replication of epistasis influencing transcription in humans. Nature 508: 249-253.
-
(2014)
Nature
, vol.508
, pp. 249-253
-
-
Hemani, G.1
Shakhbazovk Westra, H.J.2
Eskot Henders, A.K.3
McRae, A.F.4
Yang, J.5
Metspalua Ng G.Martin6
-
86
-
-
84931839182
-
Identification of Srp9 as a febrile seizure susceptibility gene
-
Hessel EVS, deWitM, Wolterink-Donselaar IG, KarstH, de Graaff E, van Lith HA, de Bruijn E, de Sonnaville S, Verbeek NE, Lindhout D, et al. 2014. Identification of Srp9 as a febrile seizure susceptibility gene. Ann Clin Transl Neurol 1: 239-250.
-
(2014)
Ann Clin Transl Neurol
, vol.1
, pp. 239-250
-
-
Evs, H.1
Dewitm2
Wolterink-Donselaar, I.G.3
Karsth4
De Graaff, E.5
Van Lith, H.A.6
De Bruijn, E.7
De Sonnaville, S.8
Verbeek, N.E.9
Lindhout, D.10
-
87
-
-
34548432163
-
Chromosome substitution strains: A new way to study genetically complex traits
-
Hill AE, Lander ES, Nadeau JH. 2006. Chromosome substitution strains: a new way to study genetically complex traits. Methods Mol Med 128: 153-172.
-
(2006)
Methods Mol Med
, vol.128
, pp. 153-172
-
-
Hill, A.E.1
Lander, E.S.2
Nadeau, J.H.3
-
88
-
-
84878138385
-
Mitonuclear protein imbalance as a conserved longevity mechanism
-
Houtkooper RH, Mouchiroud L, Ryu D, Moullan N, Katsyuba E, Knott G, Williams RW, Auwerx J. 2013. Mitonuclear protein imbalance as a conserved longevity mechanism. Nature 497: 451-457.
-
(2013)
Nature
, vol.497
, pp. 451-457
-
-
Houtkooper, R.H.1
Mouchiroud, L.2
Ryu, D.3
Moullan, N.4
Katsyuba, E.5
Knott, G.6
Williams, R.W.7
Auwerx, J.8
-
89
-
-
84866848293
-
Epistasis dominates the genetic architecture of Drosophila quantitative traits
-
Huang W, Richards S, Carbone MA, Zhu D, Anholt RRH, Ayroles JF, Duncan L, Jordan KW, LawrenceF, Magwire MM, et al. 2012. Epistasis dominates the genetic architecture of Drosophila quantitative traits. Proc Natl Acad Sci 109: 15553-15559.
-
(2012)
Proc Natl Acad Sci
, vol.109
, pp. 15553-15559
-
-
Huang, W.1
Richards, S.2
Carbone, M.A.3
Zhu, D.4
Rrh, A.5
Ayroles, J.F.6
Duncan, L.7
Jordan, K.W.8
Lawrencef Magwire, M.M.9
-
90
-
-
0036544659
-
Microtubule-associated protein 1A is a modifier of tubby hearing (moth1)
-
Ikeda A, Zheng QY, Zuberi AR, Johnson KR, Naggert JK, Nishina PM. 2002. Microtubule-associated protein 1A is a modifier of tubby hearing (moth1). Nat Genet 30: 401-405.
-
(2002)
Nat Genet
, vol.30
, pp. 401-405
-
-
Ikeda, A.1
Zheng, Q.Y.2
Zuberi, A.R.3
Johnson, K.R.4
Naggert, J.K.5
Nishina, P.M.6
-
91
-
-
79551537130
-
Association genetics of complex traits in plants
-
Ingvarsson PK, Street NR. 2011. Association genetics of complex traits in plants. New Phytol 189: 909-922.
-
(2011)
New Phytol
, vol.189
, pp. 909-922
-
-
Ingvarsson, P.K.1
Street, N.R.2
-
93
-
-
84896739351
-
Meta-analysis identifies gene-by-environment interactions as demonstrated in a study of 4, 965 mice
-
Kang EY, Han B, Furlotte N, Joo JW, Shih D, Davis RC, Lusis AJ, Eskin E. 2014. Meta-analysis identifies gene-by-environment interactions as demonstrated in a study of 4, 965 mice. PLoS Genet 10: e1004022.
-
(2014)
PLoS Genet
, vol.10
, pp. e1004022
-
-
Kang, E.Y.1
Han, B.2
Furlotte, N.3
Joo, J.W.4
Shih, D.5
Davis, R.C.6
Lusis, A.J.7
Eskin, E.8
-
94
-
-
59149096617
-
High-resolution genetic mapping of mammalian motor activity levels in mice
-
Kas MJ, de Mooij-van Malsen JG, de Krom M, van Gassen KL, van Lith HA, Olivier B, Oppelaar H, Hendriks J, de Wit M, Groot Koerkamp MJ, et al. 2009. High-resolution genetic mapping of mammalian motor activity levels in mice. Genes Brain Behav 8: 13-22.
-
(2009)
Genes Brain Behav
, vol.8
, pp. 13-22
-
-
Kas, M.J.1
De Mooij-Van Malsen, J.G.2
De Krom, M.3
Van Gassen, K.L.4
Van Lith, H.A.5
Olivier, B.6
Oppelaar, H.7
Hendriks, J.8
De Wit, M.9
Groot Koerkamp, M.J.10
-
95
-
-
85027957038
-
Segregation of a QTL cluster for home-cage activity using a new mapping method based on regression analysis of congenic mouse strains
-
Kato S, Ishii A, Nishi A, Kuriki S, Koide T. 2014. Segregation of a QTL cluster for home-cage activity using a new mapping method based on regression analysis of congenic mouse strains. Heredity 113: 416-423.
-
(2014)
Heredity
, vol.113
, pp. 416-423
-
-
Kato, S.1
Ishii, A.2
Nishi, A.3
Kuriki, S.4
Koide, T.5
-
96
-
-
0033822064
-
Mutations inMKKS cause obesity, retinal dystrophy and renal malformations associated with Bardet-Biedl syndrome
-
Katsanis N, Beales PL, Woods MO, Lewis RA, Green JS, Parfrey PS, Ansley SJ, Davidson WS, Lupski JR. 2000. Mutations inMKKS cause obesity, retinal dystrophy and renal malformations associated with Bardet-Biedl syndrome. Nat Genet 26: 67-70.
-
(2000)
Nat Genet
, vol.26
, pp. 67-70
-
-
Katsanis, N.1
Beales, P.L.2
Woods, M.O.3
Lewis, R.A.4
Green, J.S.5
Parfrey, P.S.6
Ansley, S.J.7
Davidson, W.S.8
Lupski, J.R.9
-
97
-
-
0035929273
-
Triallelic inheritance in Bardet-Biedl syndrome, a Mendelian recessive disorder
-
KatsanisN, Ansley SJ, Badano JL, Eichers ER, Lewis RA, Hoskins BE, Scambler PJ, Davidson WS, Beales PL, Lupski JR. 2001. Triallelic inheritance in Bardet-Biedl syndrome, a Mendelian recessive disorder. Science 293: 2256-2259.
-
(2001)
Science
, vol.293
, pp. 2256-2259
-
-
Katsanisn Ansley, S.J.1
Badano, J.L.2
Eichers, E.R.3
Lewis, R.A.4
Hoskins, B.E.5
Scambler, P.J.6
Davidson, W.S.7
Beales, P.L.8
Lupski, J.R.9
-
98
-
-
0036305311
-
BBS4 is a minor contributor to Bardet-Biedl syndrome and may also participate in triallelic inheritance
-
Katsanis N, Eichers ER, Ansley SJ, Lewis RA, Kayserili H, Hoskins BE, Scambler PJ, Beales PL, Lupski JR. 2002. BBS4 is a minor contributor to Bardet-Biedl syndrome and may also participate in triallelic inheritance. Am J Hum Genet 71: 22-29.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 22-29
-
-
Katsanis, N.1
Eichers, E.R.2
Ansley, S.J.3
Lewis, R.A.4
Kayserili, H.5
Hoskins, B.E.6
Scambler, P.J.7
Beales, P.L.8
Lupski, J.R.9
-
99
-
-
80052851950
-
Mouse genomic variation and its effect on phenotypes and gene regulation
-
Keane TM, Goodstadt L, Danecek P, White MA, Wong K, Yalcin B, Heger A, Agam A, Slater G, GoodsonM, et al. 2011. Mouse genomic variation and its effect on phenotypes and gene regulation. Nature 477: 289-294.
-
(2011)
Nature
, vol.477
, pp. 289-294
-
-
Keane, T.M.1
Goodstadt, L.2
Danecek, P.3
White, M.A.4
Wong, K.5
Yalcin, B.6
Heger, A.7
Agam, A.8
Goodsonm, S.G.9
-
100
-
-
79957583944
-
Genetic modifiers ofneurological disease
-
Kearney JA. 2011. Genetic modifiers ofneurological disease. Curr Opin Genet Dev 21: 349-353.
-
(2011)
Curr Opin Genet Dev
, vol.21
, pp. 349-353
-
-
Kearney, J.A.1
-
101
-
-
84857383489
-
Genetic analysis of hematological parameters in incipient lines ofthe collaborative cross
-
Kelada SN, Aylor DL, Peck BC, Ryan JF, Tavarez U, Buus RJ, Miller DR, Chesler EJ, Threadgill DW, Churchill GA, et al. 2012. Genetic analysis of hematological parameters in incipient lines ofthe collaborative cross. G3 (Bethesda) 2: 157-165.
-
(2012)
G3 (Bethesda)
, vol.2
, pp. 157-165
-
-
Kelada, S.N.1
Aylor, D.L.2
Peck, B.C.3
Ryan, J.F.4
Tavarez, U.5
Buus, R.J.6
Miller, D.R.7
Chesler, E.J.8
Threadgill, D.W.9
Churchill, G.A.10
-
102
-
-
84906860214
-
Integrative genetic analysis of allergic inflammation in the mu-rine lung
-
Kelada SN, Carpenter DE, Aylor DL, Chines P, Rutledge H, Chesler EJ, Churchill GA, Pardo-Manuel de Villena F, Schwartz DA, Collins FS. 2014. Integrative genetic analysis of allergic inflammation in the mu-rine lung. Am J Respir Cell Mol Biol 51: 436-445.
-
(2014)
Am J Respir Cell Mol Biol
, vol.51
, pp. 436-445
-
-
Kelada, S.N.1
Carpenter, D.E.2
Aylor, D.L.3
Chines, P.4
Rutledge, H.5
Chesler, E.J.6
Churchill, G.A.7
Pardo-Manuel De Villena, F.8
Schwartz, D.A.9
Collins, F.S.10
-
103
-
-
78349246707
-
B2i) results in an overexpressing, behavior modifying allele present in classical inbred mouse strains
-
B2i) results in an overexpressing, behavior modifying allele present in classical inbred mouse strains. Genes Brain Behav 9: 925-932.
-
(2010)
Genes Brain Behav
, vol.9
, pp. 925-932
-
-
Kember, R.L.1
Fernandes, C.2
Tunbridge, E.M.3
Liu, L.4
Payá-Cano, J.L.5
Parsons, M.J.6
Schalkwyk, L.C.7
-
104
-
-
84867133601
-
Genetic and epigenetic contribution to complex traits
-
Kilpinen H, Dermitzakis ET. 2012. Genetic and epigenetic contribution to complex traits. Hum Mol Genet 21: R24-R28.
-
(2012)
Hum Mol Genet
, vol.21
, pp. R24-R28
-
-
Kilpinen, H.1
Dermitzakis, E.T.2
-
105
-
-
0031754518
-
Quantitative trait loci affecting peak bone mineral density in mice
-
Klein RF, Mitchell SR, Phillips TJ, Belknap JK, Orwoll ES. 1998. Quantitative trait loci affecting peak bone mineral density in mice. J Bone Miner Res 13: 1648-1656.
-
(1998)
J Bone Miner Res
, vol.13
, pp. 1648-1656
-
-
Klein, R.F.1
Mitchell, S.R.2
Phillips, T.J.3
Belknap, J.K.4
Orwoll, E.S.5
-
106
-
-
84891757565
-
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
-
Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, et al. 2014. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res 42: D802-D809.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. D802-D809
-
-
Koscielny, G.1
Yaikhom, G.2
Iyer, V.3
Meehan, T.F.4
Morgan, H.5
Atienza-Herrero, J.6
Blake, A.7
Chen, C.K.8
Easty, R.9
Di Fenza, A.10
-
107
-
-
33344464808
-
A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol
-
Kotowski IK, Pertsemlidis A, Luke A, Cooper RS, Vega GL, Cohen JC, Hobbs HH. 2006. A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol. Am J Hum Genet 78: 410-422.
-
(2006)
Am J Hum Genet
, vol.78
, pp. 410-422
-
-
Kotowski, I.K.1
Pertsemlidis, A.2
Luke, A.3
Cooper, R.S.4
Vega, G.L.5
Cohen, J.C.6
Hobbs, H.H.7
-
108
-
-
79951481957
-
Initial impact of the sequencing of the human genome
-
Lander ES. 2011. Initial impact of the sequencing of the human genome. Nature 470: 187-197.
-
(2011)
Nature
, vol.470
, pp. 187-197
-
-
Lander, E.S.1
-
109
-
-
77957947562
-
Hundreds of variants clustered in genomic loci and biological pathways affect human height
-
Lango Allen H, Estrada K, Lettre G, Berndt SI, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, et al. 2010. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 467: 832-838.
-
(2010)
Nature
, vol.467
, pp. 832-838
-
-
Lango Allen, H.1
Estrada, K.2
Lettre, G.3
Berndt, S.I.4
Weedon, M.N.5
Rivadeneira, F.6
Willer, C.J.7
Jackson, A.U.8
Vedantam, S.9
Raychaudhuri, S.10
-
110
-
-
0033671090
-
Embryonic stem cells and gene targeting
-
Ledermann B. 2000. Embryonic stem cells and gene targeting. Exp Physiol 85: 603-613.
-
(2000)
Exp Physiol
, vol.85
, pp. 603-613
-
-
Ledermann, B.1
-
111
-
-
0033975420
-
A major effect QTL determined by multiple genes in epileptic EL mice
-
Legare ME, Bartlett FS II, Frankel WN. 2000. A major effect QTL determined by multiple genes in epileptic EL mice. Genome Res 10: 42-48.
-
(2000)
Genome Res
, vol.10
, pp. 42-48
-
-
Legare, M.E.1
Bartlett, F.S.I.I.2
Frankel, W.N.3
-
112
-
-
84874189972
-
Genotype to phenotype: Lessons from model organisms for human genetics
-
Lehner B. 2013. Genotype to phenotype: lessons from model organisms for human genetics. Nat Rev Genet 14: 168-178.
-
(2013)
Nat Rev Genet
, vol.14
, pp. 168-178
-
-
Lehner, B.1
-
113
-
-
82555194049
-
Strains, stocks, and mutant mice
-
Elsevier Academic Press, London
-
Linder CC, Davisson MT. 2004. Strains, stocks, and mutant mice. In The laboratory mouse, pp. 25-46. Elsevier Academic Press, London.
-
(2004)
In the Laboratory Mouse
, pp. 25-46
-
-
Linder, C.C.1
Davisson, M.T.2
-
114
-
-
61449198575
-
HECTD2 is associated with susceptibility to mouse and human prion disease
-
Lloyd SE, Maytham EG, Pota H, Grizenkova J, Molou E, Uphill J, Hummerich H, Whitfield J, Alpers MP, Mead S, et al. 2009. HECTD2 is associated with susceptibility to mouse and human prion disease. PLoS Genet 5: e1000383.
-
(2009)
PLoS Genet
, vol.5
, pp. e1000383
-
-
Lloyd, S.E.1
Maytham, E.G.2
Pota, H.3
Grizenkova, J.4
Molou, E.5
Uphill, J.6
Hummerich, H.7
Whitfield, J.8
Alpers, M.P.9
Mead, S.10
-
115
-
-
77954656205
-
A Copine family member, Cpne8, is a candidate quantitative trait gene for prion disease incubation time in mouse
-
Lloyd SE, Maytham EG, Grizenkova J, Hummerich H, Collinge J. 2010. A Copine family member, Cpne8, is a candidate quantitative trait gene for prion disease incubation time in mouse. Neurogenetics 11: 185-191.
-
(2010)
Neurogenetics
, vol.11
, pp. 185-191
-
-
Lloyd, S.E.1
Maytham, E.G.2
Grizenkova, J.3
Hummerich, H.4
Collinge, J.5
-
116
-
-
84878649483
-
High-precision genetic mapping of behavioral traits in the diversity outbred mouse population: Genetic mapping of behavioral traits in the outbred mouse
-
Logan RW, Robledo RF, Recla JM, Philip VM, Bubier JA, Jay JJ, Harwood C, Wilcox T, Gatti DM, Bult CJ, et al. 2013. High-precision genetic mapping of behavioral traits in the diversity outbred mouse population: genetic mapping of behavioral traits in the outbred mouse. Genes Brain Behav 12: 424-437.
-
(2013)
Genes Brain Behav
, vol.12
, pp. 424-437
-
-
Logan, R.W.1
Robledo, R.F.2
Recla, J.M.3
Philip, V.M.4
Bubier, J.A.5
Jay, J.J.6
Harwood, C.7
Wilcox, T.8
Gatti, D.M.9
Bult, C.J.10
-
117
-
-
84906079809
-
Genotype-phenotype correlation-promiscuity in the era of next-generation sequencing
-
Lu JT, Campeau PM, Lee BH. 2014. Genotype-phenotype correlation-promiscuity in the era of next-generation sequencing. N Engl J Med 371: 593-596.
-
(2014)
N Engl J Med
, vol.371
, pp. 593-596
-
-
Lu, J.T.1
Campeau, P.M.2
Lee, B.H.3
-
118
-
-
0035671407
-
The genetic architecture of quantitative traits
-
Mackay TF. 2001. The genetic architecture of quantitative traits. Annu Rev Genet 35: 303-339.
-
(2001)
Annu Rev Genet
, vol.35
, pp. 303-339
-
-
Mackay, T.F.1
-
119
-
-
84890562372
-
Epistasis and quantitative traits: Using model organisms to study gene-gene interactions
-
Mackay TF. 2013. Epistasis and quantitative traits: using model organisms to study gene-gene interactions. Nat Rev Genet 15: 22-33.
-
(2013)
Nat Rev Genet
, vol.15
, pp. 22-33
-
-
Mackay, T.F.1
-
120
-
-
84902009909
-
Why epistasis is important for tackling complex human disease genetics
-
Mackay TF, Moore JH. 2014. Why epistasis is important for tackling complex human disease genetics. Genome Med 6: 42.
-
(2014)
Genome Med
, vol.6
, pp. 42
-
-
Mackay, T.F.1
Moore, J.H.2
-
121
-
-
80053343410
-
Why animal research needs to improve
-
Macleod M. 2011. Why animal research needs to improve. Nature 477: 511-511.
-
(2011)
Nature
, vol.477
, pp. 511-511
-
-
Macleod, M.1
-
123
-
-
33748309136
-
Common variation in three genes, including a noncoding variant in CFH, strongly influences riskofage-related macular degeneration
-
Maller J, George S, Purcell S, Fagerness J, Altshuler D, Daly MJ, Seddon JM. 2006. Common variation in three genes, including a noncoding variant in CFH, strongly influences riskofage-related macular degeneration. Nat Genet 38: 1055-1059.
-
(2006)
Nat Genet
, vol.38
, pp. 1055-1059
-
-
Maller, J.1
George, S.2
Purcell, S.3
Fagerness, J.4
Altshuler, D.5
Daly, M.J.6
Seddon, J.M.7
-
124
-
-
84880920122
-
Bringing genome-wide association findings into clinical use
-
Manolio TA. 2013. Bringing genome-wide association findings into clinical use. Nat Rev Genet 14: 549-558.
-
(2013)
Nat Rev Genet
, vol.14
, pp. 549-558
-
-
Manolio, T.A.1
-
125
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, et al. 2009. Finding the missing heritability of complex diseases. Nature 461: 747-753.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
Goldstein, D.B.4
Hindorff, L.A.5
Hunter, D.J.6
McCarthy, M.I.7
Ramos, E.M.8
Cardon, L.R.9
Chakravarti, A.10
-
126
-
-
0030659604
-
Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains
-
Markel P, Shu P, Ebeling C, Carlson GA, Nagle DL, Smutko JS, Moore KJ. 1997. Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains. Nat Genet 17: 280-284.
-
(1997)
Nat Genet
, vol.17
, pp. 280-284
-
-
Markel, P.1
Shu, P.2
Ebeling, C.3
Carlson, G.A.4
Nagle, D.L.5
Smutko, J.S.6
Moore, K.J.7
-
127
-
-
0027021941
-
The AXB and BXA set of recombinant inbred mouse strains
-
Marshall JD, Mu JL, Cheah YC, Nesbitt MN, Frankel WN, Paigen B. 1992. The AXB and BXA set of recombinant inbred mouse strains. Mamm Genome 3: 669-680.
-
(1992)
Mamm Genome
, vol.3
, pp. 669-680
-
-
Marshall, J.D.1
Mu, J.L.2
Cheah, Y.C.3
Nesbitt, M.N.4
Frankel, W.N.5
Paigen, B.6
-
128
-
-
0032881408
-
Susceptibility to testicular germ-celltumours in a 129.MOLF-Chr19 chromosome substitution strain
-
Matin A, Collin GB, Asada Y, Varnum D, Nadeau JH. 1999. Susceptibility to testicular germ-celltumours in a 129.MOLF-Chr19 chromosome substitution strain. Nat Genet 23: 237-240.
-
(1999)
Nat Genet
, vol.23
, pp. 237-240
-
-
Matin, A.1
Collin, G.B.2
Asada, Y.3
Varnum, D.4
Nadeau, J.H.5
-
129
-
-
33646293109
-
Genetic factors in alcohol preference of laboratory mice
-
McClearn GE, Rodgers DA. 1961. Genetic factors in alcohol preference of laboratory mice. J Comp Physiol Psychol 54: 116-119.
-
(1961)
J Comp Physiol Psychol
, vol.54
, pp. 116-119
-
-
McClearn, G.E.1
Rodgers, D.A.2
-
130
-
-
77951702343
-
Genetic heterogeneity in human disease
-
McClellan J, King MC. 2010. Genetic heterogeneity in human disease. Cell 141: 210-217.
-
(2010)
Cell
, vol.141
, pp. 210-217
-
-
McClellan, J.1
King, M.C.2
-
131
-
-
0031935546
-
Resistance ranking of some common inbred mouse strains to Mycobacterium tuberculosis and relationship to major histocompatibility complex haplotype and Nramp1 genotype: Resistance ranking of inbred mouse strains
-
Medina E, North RJ. 2001. Resistance ranking of some common inbred mouse strains to Mycobacterium tuberculosis and relationship to major histocompatibility complex haplotype and Nramp1 genotype: resistance ranking of inbred mouse strains. Immunology 93: 270-274.
-
(2001)
Immunology
, vol.93
, pp. 270-274
-
-
Medina, E.1
North, R.J.2
-
132
-
-
84920540903
-
Multiple blood pressure loci with opposing blood pressure effects on rat chromosome 1 in a homologous region linked to hypertension on human chromosome 15
-
Mell B, Abdul-Majeed S, Kumarasamy S, Waghulde H, Pillai R, Nie Y, Joe B. 2015. Multiple blood pressure loci with opposing blood pressure effects on rat chromosome 1 in a homologous region linked to hypertension on human chromosome 15. Hypertens Res 38: 61-67.
-
(2015)
Hypertens Res
, vol.38
, pp. 61-67
-
-
Mell, B.1
Abdul-Majeed, S.2
Kumarasamy, S.3
Waghulde, H.4
Pillai, R.5
Nie, Y.6
Joe, B.7
-
133
-
-
84902156711
-
Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density
-
Mesner LD, Ray B, Hsu YH, Manichaikul A, Lum E, Bryda EC, Rich SS, Rosen CJ, Criqui MH, Allison M, et al. 2014. Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density. J Clin Invest 124: 2736-2749.
-
(2014)
J Clin Invest
, vol.124
, pp. 2736-2749
-
-
Mesner, L.D.1
Ray, B.2
Hsu, Y.H.3
Manichaikul, A.4
Lum, E.5
Bryda, E.C.6
Rich, S.S.7
Rosen, C.J.8
Criqui, M.H.9
Allison, M.10
-
134
-
-
59649114738
-
Genetic factors for resistance to diet-induced obesity and associated metabolic traits on mouse chromosome 17
-
Millward CA, Burrage LC, Shao H, Sinasac DS, Kawasoe JH, Hill-Baskin AE, Ernest SR, Gornicka A, Hsieh CW, Pisano S, et al. 2009. Genetic factors for resistance to diet-induced obesity and associated metabolic traits on mouse chromosome 17. Mamm Genome 20: 71-82.
-
(2009)
Mamm Genome
, vol.20
, pp. 71-82
-
-
Millward, C.A.1
Burrage, L.C.2
Shao, H.3
Sinasac, D.S.4
Kawasoe, J.H.5
Hill-Baskin, A.E.6
Ernest, S.R.7
Gornicka, A.8
Hsieh, C.W.9
Pisano, S.10
-
135
-
-
0033534406
-
Mvwf, a dominant modifier of murine von Willebrand factor, results from altered lineage-specific expression of a glycosyltransferase
-
Mohlke KL, Purkayastha AA, Westrick RJ, Smith PL, Petryniak B, Lowe JB, Ginsburg D. 1999. Mvwf, a dominant modifier of murine von Willebrand factor, results from altered lineage-specific expression of a glycosyltransferase. Cell 96: 111-120.
-
(1999)
Cell
, vol.96
, pp. 111-120
-
-
Mohlke, K.L.1
Purkayastha, A.A.2
Westrick, R.J.3
Smith, P.L.4
Petryniak, B.5
Lowe, J.B.6
Ginsburg, D.7
-
136
-
-
84906226932
-
A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes
-
Moltke I, Grarup N, Jørgensen ME, Bjerregaard P, Treebak JT, Fumagalli M, Korneliussen TS, Andersen MA, Nielsen TS, Krarup NT, et al. 2014. A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes. Nature 512: 190-193.
-
(2014)
Nature
, vol.512
, pp. 190-193
-
-
Moltke, I.1
Grarup, N.2
Jørgensen, M.E.3
Bjerregaard, P.4
Treebak, J.T.5
Fumagalli, M.6
Korneliussen, T.S.7
Andersen, M.A.8
Nielsen, T.S.9
Krarup, N.T.10
-
137
-
-
0034619331
-
A method for fine mapping quantitative trait loci in outbred animal stocks
-
Mott R, Talbot CJ, Turri MG, Collins AC, Flint J. 2000. A method for fine mapping quantitative trait loci in outbred animal stocks. Proc Natl Acad Sci 97: 12649-12654.
-
(2000)
Proc Natl Acad Sci
, vol.97
, pp. 12649-12654
-
-
Mott, R.1
Talbot, C.J.2
Turri, M.G.3
Collins, A.C.4
Flint, J.5
-
138
-
-
84892752841
-
The architecture of parent-of-origin effects in mice
-
Mott R, Yuan W, Kaisaki P, Gan X, Cleak J, Edwards A, Baud A, Flint J. 2014. The architecture of parent-of-origin effects in mice. Cell 156: 332-342.
-
(2014)
Cell
, vol.156
, pp. 332-342
-
-
Mott, R.1
Yuan, W.2
Kaisaki, P.3
Gan, X.4
Cleak, J.5
Edwards, A.6
Baud, A.7
Flint, J.8
-
139
-
-
0035287508
-
Modifier genes in mice and humans
-
Nadeau JH. 2001. Modifier genes in mice and humans. Nat Rev Genet 2: 165-174.
-
(2001)
Nat Rev Genet
, vol.2
, pp. 165-174
-
-
Nadeau, J.H.1
-
140
-
-
0038012541
-
Modifier genes and protective allelesin humans and mice
-
Nadeau JH. 2003. Modifier genes and protective allelesin humans and mice. Curr Opin Genet Dev 13: 290-295.
-
(2003)
Curr Opin Genet Dev
, vol.13
, pp. 290-295
-
-
Nadeau, J.H.1
-
141
-
-
79952048799
-
Systems genetics
-
Nadeau JH, Dudley AM. 2011. Systems genetics. Science 331: 1015-1016.
-
(2011)
Science
, vol.331
, pp. 1015-1016
-
-
Nadeau, J.H.1
Dudley, A.M.2
-
142
-
-
0034054962
-
Analysing complex genetic traits with chromosome substitution strains
-
Nadeau JH, Singer JB, Matin A, Lander ES. 2000. Analysing complex genetic traits with chromosome substitution strains. Nat Genet 24: 221-225.
-
(2000)
Nat Genet
, vol.24
, pp. 221-225
-
-
Nadeau, J.H.1
Singer, J.B.2
Matin, A.3
Lander, E.S.4
-
143
-
-
0141742300
-
Pleiotropy, homeostasis, and functional networks based on assays of cardiovascular traits in genetically randomized populations
-
Nadeau JH, Burrage LC, Restivo J, Pao YH, Churchill G, Hoit BH. 2003. Pleiotropy, homeostasis, and functional networks based on assays of cardiovascular traits in genetically randomized populations. Genome Res 13: 2082-2091.
-
(2003)
Genome Res
, vol.13
, pp. 2082-2091
-
-
Nadeau, J.H.1
Burrage, L.C.2
Restivo, J.3
Pao, Y.H.4
Churchill, G.5
Hoit, B.H.6
-
144
-
-
84867336811
-
Chromosome substitution strains: Gene discovery, functional analysis, and systems studies
-
Nadeau JH, Forejt J, Takada T, Shiroishi T. 2012. Chromosome substitution strains: gene discovery, functional analysis, and systems studies. Mamm Genome 23: 693-705.
-
(2012)
Mamm Genome
, vol.23
, pp. 693-705
-
-
Nadeau, J.H.1
Forejt, J.2
Takada, T.3
Shiroishi, T.4
-
145
-
-
36849012027
-
Localization of type 1 diabetes susceptibility to the MHC class i genes HLA-B and HLA-A
-
Nejentsev S, Howson JMM, Walker NM, Szeszko J, Field SF, Stevens HE, Reynolds P, Hardy M, King E, Masters J, et al. 2007. Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. Nature 450: 887-892.
-
(2007)
Nature
, vol.450
, pp. 887-892
-
-
Nejentsev, S.1
Jmm, H.2
Walker, N.M.3
Szeszko, J.4
Field, S.F.5
Stevens, H.E.6
Reynolds, P.7
Hardy, M.8
King, E.9
Masters, J.10
-
146
-
-
77955462983
-
Transgenerational genetic effects of the paternal y chromosome on daughters' phenotypes
-
Nelson VR, Spiezio SH, Nadeau JH. 2010. Transgenerational genetic effects of the paternal Y chromosome on daughters' phenotypes. Epigenomics 2: 513-521.
-
(2010)
Epigenomics
, vol.2
, pp. 513-521
-
-
Nelson, V.R.1
Spiezio, S.H.2
Nadeau, J.H.3
-
147
-
-
84868036620
-
Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages
-
Orozco LD, Bennett BJ, Farber CR, Ghazalpour A, Pan C, Che N, Wen P, Qi HX, Mutukulu A, Siemers N, et al. 2012. Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages. Cell 151: 658-670.
-
(2012)
Cell
, vol.151
, pp. 658-670
-
-
Orozco, L.D.1
Bennett, B.J.2
Farber, C.R.3
Ghazalpour, A.4
Pan, C.5
Che, N.6
Wen, P.7
Qi, H.X.8
Mutukulu, A.9
Siemers, N.10
-
148
-
-
84884878742
-
Genetic variants regulating immune cell levels in health and disease
-
Orrù V, Steri M, Sole G, Sidore C, Virdis F, Dei M, Lai S, Zoledziewska M, Busonero F, Mulas A, et al. 2013. Genetic variants regulating immune cell levels in health and disease. Cell 155: 242-256.
-
(2013)
Cell
, vol.155
, pp. 242-256
-
-
Orrù, V.1
Steri, M.2
Sole, G.3
Sidore, C.4
Virdis, F.5
Dei, M.6
Lai, S.7
Zoledziewska, M.8
Busonero, F.9
Mulas, A.10
-
149
-
-
0022003324
-
Variation in susceptibility to atherosclerosis among inbred strains of mice
-
Paigen B, Morrow A, Brandon C, Mitchell D, Holmes P. 1985. Variation in susceptibility to atherosclerosis among inbred strains of mice. Atherosclerosis 57: 65-73.
-
(1985)
Atherosclerosis
, vol.57
, pp. 65-73
-
-
Paigen, B.1
Morrow, A.2
Brandon, C.3
Mitchell, D.4
Holmes, P.5
-
150
-
-
79952602299
-
Gene networks associated with conditional fear in mice identified using a systems genetics approach
-
Park CC, Gale GD, de Jong S, Ghazalpour A, Bennett BJ, Farber CR, Langfelder P, Lin A, Khan AH, Eskin E, et al. 2011. Gene networks associated with conditional fear in mice identified using a systems genetics approach. BMC Syst Biol 5: 43.
-
(2011)
BMC Syst Biol
, vol.5
, pp. 43
-
-
Park, C.C.1
Gale, G.D.2
De Jong, S.3
Ghazalpour, A.4
Bennett, B.J.5
Farber, C.R.6
Langfelder, P.7
Lin, A.8
Khan, A.H.9
Eskin, E.10
-
151
-
-
84872156123
-
Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice
-
Parks BW, Nam E, Org E, Kostem E, Norheim F, Hui ST, Pan C, Civelek M, Rau CD, Bennett BJ, et al. 2013. Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice. Cell Metab 17: 141-152.
-
(2013)
Cell Metab
, vol.17
, pp. 141-152
-
-
Parks, B.W.1
Nam, E.2
Org, E.3
Kostem, E.4
Norheim, F.5
Hui, S.T.6
Pan, C.7
Civelek, M.8
Rau, C.D.9
Bennett, B.J.10
-
152
-
-
25444501564
-
A new set of BXD recom-binant inbred lines from advanced intercross populations in mice
-
Peirce JL, Lu L, GuJ, Silver LM, Williams RW. 2004. A new set of BXD recom-binant inbred lines from advanced intercross populations in mice. BMC Genet 5: 7.
-
(2004)
BMC Genet
, vol.5
, pp. 7
-
-
Peirce, J.L.1
Lu, L.2
Guj Silver, L.M.3
Williams, R.W.4
-
153
-
-
33845732301
-
The mouse as a model for human biology: A resource guide for complex trait analysis
-
Peters LL, Robledo RF, Bult CJ, Churchill GA, Paigen BJ, Svenson KL. 2007. The mouse as a model for human biology: a resource guide for complex trait analysis. Nat Rev Genet 8: 58-69.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 58-69
-
-
Peters, L.L.1
Robledo, R.F.2
Bult, C.J.3
Churchill, G.A.4
Paigen, B.J.5
Svenson, K.L.6
-
154
-
-
80051562374
-
Genetic analysis in the Collaborative Cross breeding population
-
Philip VM, Sokoloff G, Ackert-Bicknell CL, Striz M, Branstetter L, Beckmann MA, Spence JS, Jackson BL, Galloway LD, Barker P, et al. 2011. Genetic analysis in the Collaborative Cross breeding population. Genome Res 21: 1223-1238.
-
(2011)
Genome Res
, vol.21
, pp. 1223-1238
-
-
Philip, V.M.1
Sokoloff, G.2
Ackert-Bicknell, C.L.3
Striz, M.4
Branstetter, L.5
Beckmann, M.A.6
Spence, J.S.7
Jackson, B.L.8
Galloway, L.D.9
Barker, P.10
-
155
-
-
84895886695
-
Using the emerging Collaborative Cross to probe the immune system
-
Phillippi J, Xie Y, Miller DR, Bell TA, Zhang Z, Lenarcic AB, Aylor DL, Krovi SH, Threadgill DW, Pardo-Manuel de Villena F, et al. 2014. Using the emerging Collaborative Cross to probe the immune system. Genes Immun 15: 38-46.
-
(2014)
Genes Immun
, vol.15
, pp. 38-46
-
-
Phillippi, J.1
Xie, Y.2
Miller, D.R.3
Bell, T.A.4
Zhang, Z.5
Lenarcic, A.B.6
Aylor, D.L.7
Krovi, S.H.8
Threadgill, D.W.9
Pardo-Manuel De Villena, F.10
-
157
-
-
84880554676
-
Zbtb16 has arolein brown adipocyte bioenergetics
-
Plaisier CL, Bennett BJ, He A, Guan B, Lusis AJ, Reue K, Vergnes L. 2012. Zbtb16 has arolein brown adipocyte bioenergetics. Nutr Diabetes 2: e46.
-
(2012)
Nutr Diabetes
, vol.2
, pp. e46
-
-
Plaisier, C.L.1
Bennett, B.J.2
He, A.3
Guan, B.4
Lusis, A.J.5
Reue, K.6
Vergnes, L.7
-
159
-
-
80055088241
-
Believe it or not: How much can we rely onpublished dataon potential drug targets?
-
Prinz F, Schlange T, Asadullah K. 2011. Believe it or not: how much can we rely onpublished dataon potential drug targets? Nat Rev Drug Discov 10: 712.
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 712
-
-
Prinz, F.1
Schlange, T.2
Asadullah, K.3
-
160
-
-
84911371938
-
Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance
-
Rasmussen AL, OkumuraA, Ferris MT, Green R, Feldmann F, Kelly SM, Scott DP, Safronetz D, Haddock E, LaCasse R, et al. 2014. Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance. Science 346: 987-991.
-
(2014)
Science
, vol.346
, pp. 987-991
-
-
Rasmussen, A.L.1
Okumuraa Ferris, M.T.2
Green, R.3
Feldmann, F.4
Kelly, S.M.5
Scott, D.P.6
Safronetz, D.7
Haddock, E.8
Lacasse, R.9
-
161
-
-
84924576455
-
Mapping genetic contributions to cardiac pathology induced by β-adrenergic stimulation in mice
-
Rau CD, Wang J, Avetisyan R, Romay M, Martin L, Ren S, Wang Y, Lusis AJ. 2015. Mapping genetic contributions to cardiac pathology induced by β-adrenergic stimulation in mice. Circ Cardiovasc Genet 8: 40-49.
-
(2015)
Circ Cardiovasc Genet
, vol.8
, pp. 40-49
-
-
Rau, C.D.1
Wang, J.2
Avetisyan, R.3
Romay, M.4
Martin, L.5
Ren, S.6
Wang, Y.7
Lusis, A.J.8
-
162
-
-
84902126970
-
Precise genetic mapping and integrative bioinformatics in Diversity Outbred mice reveals Hydin as a novel pain gene
-
Recla JM, Robledo RF, Gatti DM, Bult CJ, Churchill GA, Chesler EJ. 2014. Precise genetic mapping and integrative bioinformatics in Diversity Outbred mice reveals Hydin as a novel pain gene. Mamm Genome 25: 211-222.
-
(2014)
Mamm Genome
, vol.25
, pp. 211-222
-
-
Recla, J.M.1
Robledo, R.F.2
Gatti, D.M.3
Bult, C.J.4
Churchill, G.A.5
Chesler, E.J.6
-
163
-
-
80054975975
-
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease
-
Rivas MA, Beaudoin M, Gardet A, Stevens C, Sharma Y, Zhang CK, Boucher G, Ripke S, Ellinghaus D, Burtt N, et al. 2011. Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease. Nat Genet 43: 1066-1073.
-
(2011)
Nat Genet
, vol.43
, pp. 1066-1073
-
-
Rivas, M.A.1
Beaudoin, M.2
Gardet, A.3
Stevens, C.4
Sharma, Y.5
Zhang, C.K.6
Boucher, G.7
Ripke, S.8
Ellinghaus, D.9
Burtt, N.10
-
164
-
-
84855800307
-
Mutation of Rubie, a novel long non-coding RNA located upstream of Bmp4, causes vestibular malformation in mice
-
Roberts KA, Abraira VE, Tucker AF, Goodrich LV, Andrews NC. 2012. Mutation of Rubie, a novel long non-coding RNA located upstream of Bmp4, causes vestibular malformation in mice. PLoS One 7: e29495.
-
(2012)
PLoS One
, vol.7
, pp. e29495
-
-
Roberts, K.A.1
Abraira, V.E.2
Tucker, A.F.3
Goodrich, L.V.4
Andrews, N.C.5
-
165
-
-
84897058188
-
Explaining additional genetic variation in complex traits
-
Robinson MR, Wray NR, Visscher PM. 2014. Explaining additional genetic variation in complex traits. Trends Genet 30: 124-132.
-
(2014)
Trends Genet
, vol.30
, pp. 124-132
-
-
Robinson, M.R.1
Wray, N.R.2
Visscher, P.M.3
-
166
-
-
84897108137
-
The Collaborative Cross as a resource for modeling human disease: CC011/Unc, a new mouse model for spontaneous colitis
-
Rogala AR, Morgan AP, Christensen AM, Gooch TJ, Bell TA, Miller DR, Godfrey VL, de Villena FP. 2014. The Collaborative Cross as a resource for modeling human disease: CC011/Unc, a new mouse model for spontaneous colitis. Mamm Genome 25: 95-108.
-
(2014)
Mamm Genome
, vol.25
, pp. 95-108
-
-
Rogala, A.R.1
Morgan, A.P.2
Christensen, A.M.3
Gooch, T.J.4
Bell, T.A.5
Miller, D.R.6
Godfrey, V.L.7
De Villena, F.P.8
-
167
-
-
84879223834
-
The albino mutation of tyrosinase alters ocular angiogenic responsiveness
-
Rogers MS, Adini I, McBride AF, Birsner AE, D'Amato RJ. 2013. The albino mutation of tyrosinase alters ocular angiogenic responsiveness. Angiogenesis 16: 639-646.
-
(2013)
Angiogenesis
, vol.16
, pp. 639-646
-
-
Rogers, M.S.1
Adini, I.2
McBride, A.F.3
Birsner, A.E.4
D'Amato, R.J.5
-
168
-
-
84908024349
-
Genetic regulation of Zfp30 CXCL1 and neutrophilic inflammation in mouse lung
-
Rutledge H, Aylor DL, Carpenter DE, Peck BC, Chines P, Ostrowski LE, Chesler EJ, Churchill GA, de Villena FP, Kelada SN. 2014. Genetic regulation of Zfp30, CXCL1, and neutrophilic inflammation in mouse lung. Genetics 198: 735-745.
-
(2014)
Genetics
, vol.198
, pp. 735-745
-
-
Rutledge, H.1
Aylor, D.L.2
Carpenter, D.E.3
Peck, B.C.4
Chines, P.5
Ostrowski, L.E.6
Chesler, E.J.7
Churchill, G.A.8
De Villena, F.P.9
Kelada, S.N.10
-
169
-
-
52549117003
-
Quantitative trait locus analysis for hemostasis and thrombosis
-
Sa Q, Hart E, Hill AE, Nadeau JH, Hoover-Plow JL. 2008. Quantitative trait locus analysis for hemostasis and thrombosis. Mamm Genome 19: 406-412.
-
(2008)
Mamm Genome
, vol.19
, pp. 406-412
-
-
Sa, Q.1
Hart, E.2
Hill, A.E.3
Nadeau, J.H.4
Hoover-Plow, J.L.5
-
170
-
-
79960943621
-
Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability
-
Sanna S, Li B, Mulas A, Sidore C, Kang HM, Jackson AU, Piras MG, Usala G, Maninchedda G, Sassu A, et al. 2011. Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability. PLoS Genet 7: e1002198.
-
(2011)
PLoS Genet
, vol.7
, pp. e1002198
-
-
Sanna, S.1
Li, B.2
Mulas, A.3
Sidore, C.4
Kang, H.M.5
Jackson, A.U.6
Piras, M.G.7
Usala, G.8
Maninchedda, G.9
Sassu, A.10
-
171
-
-
84885896174
-
Controlling complexity: The clinical relevance of mouse complex genetics
-
Schughart K, Libert C, Kas MJ. 2013. Controlling complexity: the clinical relevance of mouse complex genetics. Eur J Hum Genet 21: 1191-1196.
-
(2013)
Eur J Hum Genet
, vol.21
, pp. 1191-1196
-
-
Schughart, K.1
Libert, C.2
Kas, M.J.3
-
172
-
-
58149396842
-
Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis
-
Shao H, Burrage LC, Sinasac DS, Hill AE, Ernest SR, O'Brien W, Courtland HW, Jepsen KJ, Kirby A, Kulbokas EJ, et al. 2008. Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis. Proc Natl Acad Sci 105: 19910-19914.
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 19910-19914
-
-
Shao, H.1
Burrage, L.C.2
Sinasac, D.S.3
Hill, A.E.4
Ernest, S.R.5
O'Brien, W.6
Courtland, H.W.7
Jepsen, K.J.8
Kirby, A.9
Kulbokas, E.J.10
-
173
-
-
77955656946
-
Analyzing complex traits with con-genic strains
-
Shao H, Sinasac D, Burrage L, Hodges C, Supelak P, Palmert M, Moreno C, Cowley A, Jacob H, Nadeau J. 2010. Analyzing complex traits with con-genic strains. Mamm Genome 21: 276-286.
-
(2010)
Mamm Genome
, vol.21
, pp. 276-286
-
-
Shao, H.1
Sinasac, D.2
Burrage, L.3
Hodges, C.4
Supelak, P.5
Palmert, M.6
Moreno, C.7
Cowley, A.8
Jacob, H.9
Nadeau, J.10
-
175
-
-
15544382002
-
Mapping quantitative trait loci for anxiety in chromosome substitution strains of mice
-
Singer JB. 2005. Mapping quantitative trait loci for anxiety in chromosome substitution strains of mice. Genetics 169: 855-862.
-
(2005)
Genetics
, vol.169
, pp. 855-862
-
-
Singer, J.B.1
-
176
-
-
11144355685
-
Genetic dissection ofcomplex traits with chromosome substitution strains of mice
-
Singer JB, Hill AE, Burrage LC, Olszens KR, Song J, Justice M, O'Brien WE, Conti DV, Witte JS, Lander ES, etal. 2004. Genetic dissection ofcomplex traits with chromosome substitution strains of mice. Science 304: 445-448.
-
(2004)
Science
, vol.304
, pp. 445-448
-
-
Singer, J.B.1
Hill, A.E.2
Burrage, L.C.3
Olszens, K.R.4
Song, J.5
Justice, M.6
O'Brien, W.E.7
Conti, D.V.8
Witte, J.S.9
Lander, E.S.10
Etal11
-
177
-
-
84964315530
-
High-resolution genetic mapping in the diversity outbred mouse population identifies Apobec1 as a candidate gene for atherosclerosis
-
Smallwood TL, Gatti DM, Quizon P, Weinstock GM, Jung KC, Zhao L, Hua K, Pomp D, Bennett BJ. 2014. High-resolution genetic mapping in the diversity outbred mouse population identifies Apobec1 as a candidate gene for atherosclerosis. G3 (Bethesda) 4: 2353-2363.
-
(2014)
G3 (Bethesda)
, vol.4
, pp. 2353-2363
-
-
Smallwood, T.L.1
Gatti, D.M.2
Quizon, P.3
Weinstock, G.M.4
Jung, K.C.5
Zhao, L.6
Hua, K.7
Pomp, D.8
Bennett, B.J.9
-
178
-
-
84863729639
-
Genetic locus on mouse chromosome 7 controls elevated heart rate
-
Smolock EM, Ilyushkina IA, GhazalpourA, Gerloff J, Murashev AN, Lusis AJ, Korshunov VA. 2012. Genetic locus on mouse chromosome 7 controls elevated heart rate. Physiol Genomics 44: 689-698.
-
(2012)
Physiol Genomics
, vol.44
, pp. 689-698
-
-
Smolock, E.M.1
Ilyushkina, I.A.2
Ghazalpoura Gerloff, J.3
Murashev, A.N.4
Lusis, A.J.5
Korshunov, V.A.6
-
179
-
-
84901036355
-
Epigenetic inheritance of metabolic state
-
Somer RA, Thummel CS. 2014. Epigenetic inheritance of metabolic state. Curr Opin Genet Dev 27: 43-47.
-
(2014)
Curr Opin Genet Dev
, vol.27
, pp. 43-47
-
-
Somer, R.A.1
Thummel, C.S.2
-
180
-
-
84861108449
-
Genetic divergence and the genetic architecture of complex traits in chromosome substitution strains of mice
-
Spiezio SH, Takada T, Shiroishi T, Nadeau JH. 2012. Genetic divergence and the genetic architecture of complex traits in chromosome substitution strains of mice. BMC Genet 13: 38.
-
(2012)
BMC Genet
, vol.13
, pp. 38
-
-
Spiezio, S.H.1
Takada, T.2
Shiroishi, T.3
Nadeau, J.H.4
-
181
-
-
84911999997
-
Genetic determinants of atherosclerosis, obesity, and energy balance in consomic mice
-
Spiezio SH, Amon LM, McMillen TS, Vick CM, Houston BA, Caldwell M, Ogimoto K, Morton GJ, Kirk EA, Schwartz MW, et al. 2014. Genetic determinants of atherosclerosis, obesity, and energy balance in consomic mice. Mamm Genome 25: 549-563.
-
(2014)
Mamm Genome
, vol.25
, pp. 549-563
-
-
Spiezio, S.H.1
Amon, L.M.2
McMillen, T.S.3
Vick, C.M.4
Houston, B.A.5
Caldwell, M.6
Ogimoto, K.7
Morton, G.J.8
Kirk, E.A.9
Schwartz, M.W.10
-
182
-
-
0023791475
-
Influenza virus-susceptible mice carry Mx genes with a large deletion or a nonsense mutation
-
Staeheli P, Grob R, Meier E, Sutcliffe JG, Haller O. 1988. Influenza virus-susceptible mice carry Mx genes with a large deletion or a nonsense mutation. Mol Cell Biol 8: 4518-4523.
-
(1988)
Mol Cell Biol
, vol.8
, pp. 4518-4523
-
-
Staeheli, P.1
Grob, R.2
Meier, E.3
Sutcliffe, J.G.4
Haller, O.5
-
183
-
-
0037149488
-
Dissecting the architecture ofa quantitative trait locus in yeast
-
Steinmetz LM, Sinha H, Richards DR, Spiegelman JI, Oefner PJ, McCusker JH, Davis RW. 2002. Dissecting the architecture ofa quantitative trait locus in yeast. Nature 416: 326-330.
-
(2002)
Nature
, vol.416
, pp. 326-330
-
-
Steinmetz, L.M.1
Sinha, H.2
Richards, D.R.3
Spiegelman, J.I.4
Oefner, P.J.5
McCusker, J.H.6
Davis, R.W.7
-
184
-
-
84907190127
-
Resistance to noise-induced hearing loss in 129S6 and MOLF mice: Identification of independent, overlapping, and interacting chromosomal regions
-
Street VA, Kujawa SG, Manichaikul A, Broman KW, Kallman JC, Shilling DJ, Iwata AJ, Robinson LC, Robbins CA, Li J, et al. 2014. Resistance to noise-induced hearing loss in 129S6 and MOLF mice: identification of independent, overlapping, and interacting chromosomal regions. J Assoc Res Otolaryngol 15: 721-738.
-
(2014)
J Assoc Res Otolaryngol
, vol.15
, pp. 721-738
-
-
Street, V.A.1
Kujawa, S.G.2
Manichaikul, A.3
Broman, K.W.4
Kallman, J.C.5
Shilling, D.J.6
Iwata, A.J.7
Robinson, L.C.8
Robbins, C.A.9
Li, J.10
-
185
-
-
77957914609
-
The psychiatric GWAS consortium: Big science comes to psychiatry
-
Sullivan PF. 2010. The psychiatric GWAS consortium: big science comes to psychiatry. Neuron 68: 182-186.
-
(2010)
Neuron
, vol.68
, pp. 182-186
-
-
Sullivan, P.F.1
-
186
-
-
0024229140
-
Diet-induced type II diabetes in C57BL/6J mice
-
Surwit RS, Kuhn CM, Cochrane C, McCubbin JA, Feinglos MN. 1988. Diet-induced type II diabetes in C57BL/6J mice. Diabetes 37: 1163-1167.
-
(1988)
Diabetes
, vol.37
, pp. 1163-1167
-
-
Surwit, R.S.1
Kuhn, C.M.2
Cochrane, C.3
McCubbin, J.A.4
Feinglos, M.N.5
-
187
-
-
84857410370
-
High-resolution genetic mapping using the Mouse Diversity outbred population
-
Svenson KL, Gatti DM, Valdar W, Welsh CE, Cheng R, Chesler EJ, Palmer AA, McMillan L, Churchill GA. 2012. High-resolution genetic mapping using the Mouse Diversity outbred population. Genetics 190: 437-447.
-
(2012)
Genetics
, vol.190
, pp. 437-447
-
-
Svenson, K.L.1
Gatti, D.M.2
Valdar, W.3
Welsh, C.E.4
Cheng, R.5
Chesler, E.J.6
Palmer, A.A.7
McMillan, L.8
Churchill, G.A.9
-
188
-
-
40449090767
-
Mouse inter-subspecific consomic strains for genetic dissection of quantitative complex traits
-
Takada T, Mita A, Maeno A, Sakai T, Shitara H, Kikkawa Y, Moriwaki K, Yonekawa H, Shiroishi T. 2008. Mouse inter-subspecific consomic strains for genetic dissection of quantitative complex traits. Genome Res 18: 500-508.
-
(2008)
Genome Res
, vol.18
, pp. 500-508
-
-
Takada, T.1
Mita, A.2
Maeno, A.3
Sakai, T.4
Shitara, H.5
Kikkawa, Y.6
Moriwaki, K.7
Yonekawa, H.8
Shiroishi, T.9
-
189
-
-
84867136843
-
Genetic analysis of albuminuria in collaborative cross and multiple mouse intercross populations
-
Thaisz J, Tsaih SW, Feng M, Philip VM, Zhang Y, Yanas L, Sheehan S, Xu L, Miller DR, Paigen B, et al. 2012. Genetic analysis of albuminuria in collaborative cross and multiple mouse intercross populations. AmJ Physiol Renal Physiol 303: F972-F981.
-
(2012)
AmJ Physiol Renal Physiol
, vol.303
, pp. F972-F981
-
-
Thaisz, J.1
Tsaih, S.W.2
Feng, M.3
Philip, V.M.4
Zhang, Y.5
Yanas, L.6
Sheehan, S.7
Xu, L.8
Miller, D.R.9
Paigen, B.10
-
191
-
-
0036215090
-
Genetic dissection of complex and quantitative traits: From fantasy to reality via a community effort
-
Threadgill DW, Hunter KW, Williams RW. 2002. Genetic dissection of complex and quantitative traits: from fantasy to reality via a community effort. Mamm Genome 13: 175-178.
-
(2002)
Mamm Genome
, vol.13
, pp. 175-178
-
-
Threadgill, D.W.1
Hunter, K.W.2
Williams, R.W.3
-
192
-
-
79958045197
-
The collaborative cross:a recombinant inbred mouse population for the systems genetic era
-
Threadgill DW, Miller DR, Churchill GA, de Villena FP. 2011. The collaborative cross:a recombinant inbred mouse population for the systems genetic era. ILAR J 52: 24-31.
-
(2011)
ILAR J
, vol.52
, pp. 24-31
-
-
Threadgill, D.W.1
Miller, D.R.2
Churchill, G.A.3
De Villena, F.P.4
-
193
-
-
33645217146
-
Simulating the collaborative cross: Power of quantitative trait loci detection and mapping resolution in large sets of recombinant inbred strains of mice
-
Valdar W, Flint J, Mott R. 2006a. Simulating the collaborative cross: power of quantitative trait loci detection and mapping resolution in large sets of recombinant inbred strains of mice. Genetics 172: 1783-1797.
-
(2006)
Genetics
, vol.172
, pp. 1783-1797
-
-
Valdar, W.1
Flint, J.2
Mott, R.3
-
194
-
-
33746540478
-
Genome-wide genetic association of complex traits in heterogeneous stock mice
-
Valdar W, Solberg LC, Gauguier D, Burnett S, Klenerman P, Cookson WO, Taylor MS, Rawlins JNP, Mott R, Flint J. 2006b.Genome-wide genetic association of complex traits in heterogeneous stock mice. Nat Genet 38: 879-887.
-
(2006)
Nat Genet
, vol.38
, pp. 879-887
-
-
Valdar, W.1
Solberg, L.C.2
Gauguier, D.3
Burnett, S.4
Klenerman, P.5
Cookson, W.O.6
Taylor, M.S.7
Jnp, R.8
Mott, R.9
Flint, J.10
-
195
-
-
84855661466
-
Travelling the world of gene-gene interactions
-
Van Steen K. 2012. Travelling the world of gene-gene interactions. Brief Bioinform 13: 1-19.
-
(2012)
Brief Bioinform
, vol.13
, pp. 1-19
-
-
Van Steen, K.1
-
196
-
-
84875634736
-
Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study
-
Velez Edwards DR, Naj AC, Monda K, North KE, Neuhouser M, Magvanjav O, Kusimo I, Vitolins MZ, Manson JE, O'Sullivan MJ, et al. 2012. Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study. Hum Genet 132: 323-336.
-
(2012)
Hum Genet
, vol.132
, pp. 323-336
-
-
Velez Edwards, D.R.1
Naj, A.C.2
Monda, K.3
North, K.E.4
Neuhouser, M.5
Magvanjav, O.6
Kusimo, I.7
Vitolins, M.Z.8
Manson, J.E.9
O'Sullivan, M.J.10
-
197
-
-
84964315839
-
Susceptibility to klebsiella pneu-monaie infection in collaborative cross mice is acomplex trait controlled by at least three loci acting at different time points
-
Vered K, Durrant C, Mott R, Iraqi FA. 2014. Susceptibility to klebsiella pneu-monaie infection in collaborative cross mice is acomplex trait controlled by at least three loci acting at different time points. BMC Genomics 15: 865.
-
(2014)
BMC Genomics
, vol.15
, pp. 865
-
-
Vered, K.1
Durrant, C.2
Mott, R.3
Iraqi, F.A.4
-
198
-
-
42649123990
-
Sizing up human height variation
-
Visscher PM. 2008. Sizing up human height variation. Nat Genet 40: 489-490.
-
(2008)
Nat Genet
, vol.40
, pp. 489-490
-
-
Visscher, P.M.1
-
200
-
-
83155177118
-
Genetic interactions and modifier genes in Hirschsprung's disease
-
Wallace AS, Anderson RB. 2011. Genetic interactions and modifier genes in Hirschsprung's disease. World J Gastroenterol 17: 4937.
-
(2011)
World J Gastroenterol
, vol.17
, pp. 4937
-
-
Wallace, A.S.1
Anderson, R.B.2
-
201
-
-
79959352442
-
A QTL on chro-mosome10modulates cone photoreceptor number inthe mouse retina
-
Whitney IE, Raven MA, Lu L, Williams RW, Reese BE. 2011. A QTL on chro-mosome10modulates cone photoreceptor number inthe mouse retina. Invest Ophthalmol Vis Sci 52: 3228-3236.
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 3228-3236
-
-
Whitney, I.E.1
Raven, M.A.2
Lu, L.3
Williams, R.W.4
Reese, B.E.5
-
202
-
-
33846786438
-
Use of chromosome substitution strains to identify seizure susceptibility loci in mice
-
Winawer MR, Kuperman R, Niethammer M, Sherman S, Rabinowitz D, Guell IP, Ponder CA, Palmer AA. 2007. Use of chromosome substitution strains to identify seizure susceptibility loci in mice. Mamm Genome 18: 23-31.
-
(2007)
Mamm Genome
, vol.18
, pp. 23-31
-
-
Winawer, M.R.1
Kuperman, R.2
Niethammer, M.3
Sherman, S.4
Rabinowitz, D.5
Guell, I.P.6
Ponder, C.A.7
Palmer, A.A.8
-
203
-
-
84896816656
-
A locus on mouse Ch10 influences susceptibility to limbic seizure severity: Fine mapping and in silico candidate gene analysis: Identification of candidate genes for mouse limbic seizure susceptibility
-
Winawer MR, Klassen TL, Teed S, Shipman M, Leung EH, Palmer AA. 2014. A locus on mouse Ch10 influences susceptibility to limbic seizure severity: fine mapping and in silico candidate gene analysis: identification of candidate genes for mouse limbic seizure susceptibility. Genes Brain Behav 13: 341-349.
-
(2014)
Genes Brain Behav
, vol.13
, pp. 341-349
-
-
Winawer, M.R.1
Klassen, T.L.2
Teed, S.3
Shipman, M.4
Leung, E.H.5
Palmer, A.A.6
-
204
-
-
84908890496
-
Defining the role of common variation in the genomic and biological architecture of adult human height
-
Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K, Luan J, Kutalik Z, et al. 2014. Defining the role of common variation in the genomic and biological architecture of adult human height. Nat Genet 46: 1173-1186.
-
(2014)
Nat Genet
, vol.46
, pp. 1173-1186
-
-
Wood, A.R.1
Esko, T.2
Yang, J.3
Vedantam, S.4
Pers, T.H.5
Gustafsson, S.6
Chu, A.Y.7
Estrada, K.8
Luan, J.9
Kutalik, Z.10
-
205
-
-
84908077262
-
Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population
-
Wu Y, Williams EG, Dubuis S, Mottis A, Jovaisaite V, Houten SM, Argmann CA, Faridi P, Wolski W, Kutalik Z, et al. 2014. Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population. Cell 158: 1415-1430.
-
(2014)
Cell
, vol.158
, pp. 1415-1430
-
-
Wu, Y.1
Williams, E.G.2
Dubuis, S.3
Mottis, A.4
Jovaisaite, V.5
Houten, S.M.6
Argmann, C.A.7
Faridi, P.8
Wolski, W.9
Kutalik, Z.10
-
206
-
-
84867336198
-
Association studies in outbred mice in a new era of full-genome sequencing
-
Yalcin B, Flint J. 2012. Association studies in outbred mice in a new era of full-genome sequencing. Mamm Genome 23: 719-726.
-
(2012)
Mamm Genome
, vol.23
, pp. 719-726
-
-
Yalcin, B.1
Flint, J.2
-
207
-
-
11844254278
-
Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice
-
Yalcin B, Willis-Owen SA, Fullerton J, Meesaq A, Deacon RM, Rawlins JNP, Copley RR, Morris AP, Flint J, Mott R. 2004. Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice. Nat Genet 36: 1197-1202.
-
(2004)
Nat Genet
, vol.36
, pp. 1197-1202
-
-
Yalcin, B.1
Willis-Owen, S.A.2
Fullerton, J.3
Meesaq, A.4
Deacon, R.M.5
Jnp, R.6
Copley, R.R.7
Morris, A.P.8
Flint, J.9
Mott, R.10
-
208
-
-
78049422154
-
Commercially available outbred mice for genome-wide association studies
-
Yalcin B, Nicod J, Bhomra A, Davidson S, Cleak J, Farinelli L, Østerås M, Whitley A, Yuan W, Gan X, et al. 2010. Commercially available outbred mice for genome-wide association studies. PLoS Genet 6: e1001085.
-
(2010)
PLoS Genet
, vol.6
, pp. e1001085
-
-
Yalcin, B.1
Nicod, J.2
Bhomra, A.3
Davidson, S.4
Cleak, J.5
Farinelli, L.6
Østerås, M.7
Whitley, A.8
Yuan, W.9
Gan, X.10
-
209
-
-
84903464217
-
Dusp3 and Psme3 are associated with murine susceptibility to Staphylococcus aureus infection and human sepsis
-
YanQ, Sharma-Kuinkel BK, DeshmukhH, Tsalik EL, Cyr DD, LucasJ, Woods CW, Scott WK, Sempowski GD, Thaden J, et al. 2014. Dusp3 and Psme3 are associated with murine susceptibility to Staphylococcus aureus infection and human sepsis. PLoS Pathog 10: e1004149.
-
(2014)
PLoS Pathog
, vol.10
, pp. e1004149
-
-
Yanq Sharma-Kuinkel, B.K.1
Deshmukhh Tsalik, E.L.2
Cyr, D.D.3
Lucasj Woods, C.W.4
Scott, W.K.5
Sempowski, G.D.6
Thaden, J.7
-
210
-
-
84862832570
-
Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
-
Genetic Investigation of ANthropometric Traits (GIANT) Consortium; DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Madden PAF, Heath AC, Martin NG, Montgomery GW, et al.
-
Yang J, Ferreira T, Morris AP, Medland SE, Genetic Investigation of ANthropometric Traits (GIANT) Consortium; DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium, Madden PAF, Heath AC, Martin NG, Montgomery GW, et al. 2012. Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits. Nat Genet 44: 369-375.
-
(2012)
Nat Genet
, vol.44
, pp. 369-375
-
-
Yang, J.1
Ferreira, T.2
Morris, A.P.3
Medland, S.E.4
-
211
-
-
77957887124
-
Ancestral paternal genotype controls body weight and food intake for multiple generations
-
Yazbek SN, Spiezio SH, Nadeau JH, Buchner DA. 2010. Ancestral paternal genotype controls body weight and food intake for multiple generations. Hum Mol Genet 19: 4134-4144.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 4134-4144
-
-
Yazbek, S.N.1
Spiezio, S.H.2
Nadeau, J.H.3
Buchner, D.A.4
-
212
-
-
79959888771
-
Deep con-genic analysis identifies many strong, context-dependent QTLs, one of which, Slc35b4, regulates obesity and glucose homeostasis
-
Yazbek SN, Buchner DA, Geisinger JM, Burrage LC, Spiezio SH, Zentner GE, Hsieh CW, Scacheri PC, Croniger CM, Nadeau JH. 2011. Deep con-genic analysis identifies many strong, context-dependent QTLs, one of which, Slc35b4, regulates obesity and glucose homeostasis. Genome Res 21: 1065-1073.
-
(2011)
Genome Res
, vol.21
, pp. 1065-1073
-
-
Yazbek, S.N.1
Buchner, D.A.2
Geisinger, J.M.3
Burrage, L.C.4
Spiezio, S.H.5
Zentner, G.E.6
Hsieh, C.W.7
Scacheri, P.C.8
Croniger, C.M.9
Nadeau, J.H.10
-
213
-
-
0037440729
-
Testicular cancer susceptibility in the 129.MOLF-Chr19 mouse strain: Additive effects, gene interactions and epigenetic modifications
-
Youngren KK, Nadeau JH, Matin A. 2003. Testicular cancer susceptibility in the 129.MOLF-Chr19 mouse strain: additive effects, gene interactions and epigenetic modifications. Hum Mol Genet 12: 389-398.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 389-398
-
-
Youngren, K.K.1
Nadeau, J.H.2
Matin, A.3
-
214
-
-
0001633148
-
Assessment ofhearing in80inbred strains of mice by ABR threshold analyses
-
Zheng QY, Johnson KR, Erway LC. 1999. Assessment ofhearing in80inbred strains of mice by ABR threshold analyses. Hear Res 130: 94-107.
-
(1999)
Hear Res
, vol.130
, pp. 94-107
-
-
Zheng, Q.Y.1
Johnson, K.R.2
Erway, L.C.3
-
215
-
-
84902238947
-
Tumor loci and their interactions on mouse chromosome 19 that contribute to testicular germ cell tumors
-
Zhu R, Matin A. 2014. Tumor loci and their interactions on mouse chromosome 19 that contribute to testicular germ cell tumors. BMC Genet 15: 65.
-
(2014)
BMC Genet
, vol.15
, pp. 65
-
-
Zhu, R.1
Matin, A.2
-
216
-
-
34848921114
-
Testicular germ cell tumor susceptibility genes from the consomic 129.MOLF-Chr19 mouse strain
-
Zhu R, Ji Y, Xiao L, Matin A. 2007. Testicular germ cell tumor susceptibility genes from the consomic 129.MOLF-Chr19 mouse strain. Mamm Genome 18: 584-595.
-
(2007)
Mamm Genome
, vol.18
, pp. 584-595
-
-
Zhu, R.1
Ji, Y.2
Xiao, L.3
Matin, A.4
-
217
-
-
77956923246
-
Deficiency of splicing factor 1 suppresses the occurrence of testicular germ cell tumors
-
Zhu R, Heaney J, Nadeau JH, Ali S, Matin A. 2010. Deficiency of splicing factor 1 suppresses the occurrence of testicular germ cell tumors. Cancer Res 70: 7264-7272.
-
(2010)
Cancer Res
, vol.70
, pp. 7264-7272
-
-
Zhu, R.1
Heaney, J.2
Nadeau, J.H.3
Ali, S.4
Matin, A.5
-
218
-
-
23344433484
-
Quantitative trait locus analysis using recombinant inbred intercrosses: Theoretical and empirical considerations
-
Zou F, Gelfond JA, Airey DC, Lu L, Manly KF, Williams RW, Threadgill DW. 2005. Quantitative trait locus analysis using recombinant inbred intercrosses: theoretical and empirical considerations. Genetics 170: 1299-1311.
-
(2005)
Genetics
, vol.170
, pp. 1299-1311
-
-
Zou, F.1
Gelfond, J.A.2
Airey, D.C.3
Lu, L.4
Manly, K.F.5
Williams, R.W.6
Threadgill, D.W.7
-
219
-
-
84856405512
-
The mystery of missing her-itability: Genetic interactions create phantom heritability
-
Zuk O, Hechter E, Sunyaev SR, Lander ES. 2012. The mystery of missing her-itability: genetic interactions create phantom heritability. Proc Natl Acad Sci 109: 1193-1198.
-
(2012)
Proc Natl Acad Sci
, vol.109
, pp. 1193-1198
-
-
Zuk, O.1
Hechter, E.2
Sunyaev, S.R.3
Lander, E.S.4
|