Fine-mapping at three loci known to affect fetal hemoglobin levels explains additional genetic variation

Nature Genetics

Volumn 42, Issue 12, 2010, Pages 1049-1051

  Galarneau, Geneviève ^a   Palmer, Cameron D ^b,c   Sankaran, Vijay G ^b,d   Orkin, Stuart H ^b,d,e   Hirschhorn, Joel N ^b,c,f   Lettre, Guillaume ^a,g  

^a MONTREAL HEART INSTITUTE   (Canada)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d DANA FARBER CANCER INSTITUTE   (United States)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^f HARVARD MEDICAL SCHOOL   (United States)

^g UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; HEMOGLOBIN F; PROTEIN MYB;

AFRICAN AMERICAN; ARTICLE; GENE LOCUS; GENE MAPPING; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HEMOGLOBIN BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MISSENSE MUTATION; PRIORITY JOURNAL; SICKLE CELL ANEMIA;

AFRICAN AMERICANS; ANEMIA, SICKLE CELL; BASE SEQUENCE; FETAL HEMOGLOBIN; GENETIC LOCI; GENOME, HUMAN; HUMANS; MUTATION, MISSENSE; PHYSICAL CHROMOSOME MAPPING; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 78649469071     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.707     Document Type: Article

References (15)

1. Thein, S.L. et al. Proc. Natl. Acad. Sci. USA 104, 11346-11351 (2007).
2. Menzel, S. et al. Nat. Genet. 39, 1197-1199 (2007).
3. Uda, M. et al. Proc. Natl. Acad. Sci. USA 105, 1620-1625 (2008).
4. Lettre, G. et al. Proc. Natl. Acad. Sci. USA 105, 11869-11874 (2008).
5. Sankaran, V.G. et al. Science 322, 1839-1842 (2008).
6. Sankaran, V.G. et al. Nature 460, 1093-1097 (2009).
7. Manolio, T.A. et al. Nature 461, 747-753 (2009).
8. Nejentsev, S., Walker, N., Riches, D., Egholm, M. & Todd, J.A. Science 324, 387-389 (2009).
9. Dickson, S.P., Wang, K., Krantz, I., Hakonarson, H. & Goldstein, D.B. PLoS Biol. 8, e1000294 (2010).
10. Embury, S.H. et al. Sickle Cell Disease: Basic Principles and Clinical Practice (Lippincott Williams & Wilkins, Philadelphia, Pennsylvania, USA, 1994).
11. Labie, D. et al. Proc. Natl. Acad. Sci. USA 82, 2111-2114 (1985).
12. Solovieff, N. et al. Blood 115, 1815-1822 (2010).
13. Galanello, R. et al. Blood 114, 3935-3937 (2009).
14. Nuinoon, M. et al. Hum. Genet. 127, 303-314 (2009).
15. Pilia, G. et al. PLoS Genet. 2, e132 (2006).