-
1
-
-
15944376562
-
Strategies for mapping and cloning quantitative trait genes in rodents
-
Flint, J., Valdar, W., Shifman, S. & Mott, R. Strategies for mapping and cloning quantitative trait genes in rodents. Nat. Rev. Genet. 6, 271-286 (2005).
-
(2005)
Nat. Rev. Genet.
, vol.6
, pp. 271-286
-
-
Flint, J.1
Valdar, W.2
Shifman, S.3
Mott, R.4
-
2
-
-
11144355685
-
Genetic dissection of complex traits with chromosome substitution strains of mice
-
Singer, J.B. et al. Genetic dissection of complex traits with chromosome substitution strains of mice. Science 304, 445-448 (2004).
-
(2004)
Science
, vol.304
, pp. 445-448
-
-
Singer, J.B.1
-
3
-
-
0036235042
-
Simultaneous detection and fine mapping of quantitative trait loci in mice using heterogeneous stocks
-
Mott, R. & Flint, J. Simultaneous detection and fine mapping of quantitative trait loci in mice using heterogeneous stocks. Genetics 160, 1609-1618 (2002).
-
(2002)
Genetics
, vol.160
, pp. 1609-1618
-
-
Mott, R.1
Flint, J.2
-
4
-
-
0034619331
-
A method for fine mapping quantitative trait loci in outbred animal stocks
-
Mott, R., Talbot, C.J., Turri, M.G., Collins, A.C. & Flint, J. A method for fine mapping quantitative trait loci in outbred animal stocks. Proc. Natl. Acad. Sci. USA 97, 12649-12654 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12649-12654
-
-
Mott, R.1
Talbot, C.J.2
Turri, M.G.3
Collins, A.C.4
Flint, J.5
-
5
-
-
31544436869
-
Using progenitor strain information to identify quantitative trait nucleotides in outbred mice
-
Yalcin, B., Flint, J. & Mott, R. Using progenitor strain information to identify quantitative trait nucleotides in outbred mice. Genetics 171, 673-681 (2005).
-
(2005)
Genetics
, vol.171
, pp. 673-681
-
-
Yalcin, B.1
Flint, J.2
Mott, R.3
-
6
-
-
0034892647
-
Further characterization and high-resolution mapping of quantitative trait loci for ethanol-induced locomotor activity
-
Demarest, K., Koyner, J., McCaughran, J. Jr., Cipp, L. & Hitzemann, R. Further characterization and high-resolution mapping of quantitative trait loci for ethanol-induced locomotor activity. Behav. Genet. 31, 79-91 (2001).
-
(2001)
Behav. Genet.
, vol.31
, pp. 79-91
-
-
Demarest, K.1
Koyner, J.2
McCaughran Jr., J.3
Cipp, L.4
Hitzemann, R.5
-
7
-
-
0032979854
-
High-resolution mapping of quantitative trait loci in outbred mice
-
Talbot, C.J. et al. High-resolution mapping of quantitative trait loci in outbred mice. Nat. Genet. 21, 305-308 (1999).
-
(1999)
Nat. Genet.
, vol.21
, pp. 305-308
-
-
Talbot, C.J.1
-
8
-
-
0037385196
-
Fine scale mapping of a genetic locus for conditioned fear
-
Talbot, C.J. et al. Fine scale mapping of a genetic locus for conditioned fear. Mamm. Genome 14, 223-230 (2003).
-
(2003)
Mamm. Genome
, vol.14
, pp. 223-230
-
-
Talbot, C.J.1
-
9
-
-
18744391360
-
Discussion on the meeting on 'Statistical modelling and analysis of genetic data'
-
Balding, D.J. Discussion on the meeting on 'Statistical modelling and analysis of genetic data'. J. R. Stat. Soc. Ser. B Stat. Methodol. 64, 737-775 (2002).
-
(2002)
J. R. Stat. Soc. Ser. B Stat. Methodol.
, vol.64
, pp. 737-775
-
-
Balding, D.J.1
-
10
-
-
0036606954
-
Model choice in gene mapping: What and why
-
Sillanpaa, M.J. & Corander, J. Model choice in gene mapping: what and why. Trends Genet. 18, 301-307 (2002).
-
(2002)
Trends Genet.
, vol.18
, pp. 301-307
-
-
Sillanpaa, M.J.1
Corander, J.2
-
11
-
-
0036433546
-
A model selection approach for the identification of quantitative trait loci in experimental crosses
-
Broman, K.W. & Speed, T.P. A model selection approach for the identification of quantitative trait loci in experimental crosses. J. R. Stat. Soc. Ser. B Stat. Methodol. 64, 641-656 (2002).
-
(2002)
J. R. Stat. Soc. Ser. B Stat. Methodol.
, vol.64
, pp. 641-656
-
-
Broman, K.W.1
Speed, T.P.2
-
12
-
-
0035671699
-
Bayesian methods for quantitative trait loci mapping based on model selection: Approximate analysis using the Bayesian information criterion
-
Ball, R.D. Bayesian methods for quantitative trait loci mapping based on model selection: approximate analysis using the Bayesian information criterion. Genetics 159, 1351-1364 (2001).
-
(2001)
Genetics
, vol.159
, pp. 1351-1364
-
-
Ball, R.D.1
-
13
-
-
32144458739
-
A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice
-
Solberg, L.C. et al. A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice. Mamm. Genome 17, 129-146 (2006).
-
(2006)
Mamm. Genome
, vol.17
, pp. 129-146
-
-
Solberg, L.C.1
-
14
-
-
0030211964
-
Bagging predictors
-
Breiman, L. Bagging predictors. Mach. Learn. 24, 123-140 (1996).
-
(1996)
Mach. Learn.
, vol.24
, pp. 123-140
-
-
Breiman, L.1
-
15
-
-
0035099309
-
Multi-trait QTL mapping in barley using multivariate regression
-
Hackett, C.A., Meyer, R.C. & Thomas, W.T.B. Multi-trait QTL mapping in barley using multivariate regression. Genet. Res. 77, 95-106 (2001).
-
(2001)
Genet. Res.
, vol.77
, pp. 95-106
-
-
Hackett, C.A.1
Meyer, R.C.2
Thomas, W.T.B.3
-
16
-
-
33749472024
-
Genetic and environmental effects on complex traits in mice
-
in the press
-
Valdar, W. et al. Genetic and environmental effects on complex traits in mice. Genetics (in the press).
-
Genetics
-
-
Valdar, W.1
-
17
-
-
0030450595
-
Detection of putative quantitative trait loci in line crosses under infinitesimal genetic models
-
Visscher, P.M. & Haley, C.S. Detection of putative quantitative trait loci in line crosses under infinitesimal genetic models. Theor. Appl. Genet. 93, 691-702 (1996).
-
(1996)
Theor. Appl. Genet.
, vol.93
, pp. 691-702
-
-
Visscher, P.M.1
Haley, C.S.2
-
18
-
-
11844254278
-
Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice
-
Yalcin, B. et al. Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice. Nat. Genet. 36, 1197-1202 (2004).
-
(2004)
Nat. Genet.
, vol.36
, pp. 1197-1202
-
-
Yalcin, B.1
-
19
-
-
28444467392
-
Quantitative trait loci mapped to single-nucleotide resolution in yeast
-
Deutschbauer, A.M. & Davis, R.W. Quantitative trait loci mapped to single-nucleotide resolution in yeast. Nat. Genet. 37, 1333-1340 (2005).
-
(2005)
Nat. Genet.
, vol.37
, pp. 1333-1340
-
-
Deutschbauer, A.M.1
Davis, R.W.2
-
20
-
-
2542454771
-
The genetic architecture of quantitative traits: Lessons from Drosophila
-
Mackay, T.F. The genetic architecture of quantitative traits: lessons from Drosophila. Curr. Opin. Genet. Dev. 14, 253-257 (2004).
-
(2004)
Curr. Opin. Genet. Dev.
, vol.14
, pp. 253-257
-
-
Mackay, T.F.1
-
21
-
-
0031975307
-
Experimental strategies for the genetic dissection of complex traits in animal models
-
Darvasi, A. Experimental strategies for the genetic dissection of complex traits in animal models. Nat. Genet. 18, 19-24 (1998).
-
(1998)
Nat. Genet.
, vol.18
, pp. 19-24
-
-
Darvasi, A.1
-
22
-
-
27744519434
-
Bioinformatics toolbox for narrowing rodent quantitative trait loci
-
Dipetrillo, K., Wang, X., Stylianou, I.M. & Paigen, B. Bioinformatics toolbox for narrowing rodent quantitative trait loci. Trends Genet. 21, 683-692 (2005).
-
(2005)
Trends Genet.
, vol.21
, pp. 683-692
-
-
Dipetrillo, K.1
Wang, X.2
Stylianou, I.M.3
Paigen, B.4
-
23
-
-
0025007039
-
A polymorphism affecting lipoprotein A-II translational efficiency determines high density lipoprotein size and composition
-
Doolittle, M.H., LeBoeuf, R.C., Warden, C.H., Bee, L.M. & Lusis, A.J. A polymorphism affecting lipoprotein A-II translational efficiency determines high density lipoprotein size and composition. J. Biol. Chem. 256, 16380-16388 (1990).
-
(1990)
J. Biol. Chem.
, vol.256
, pp. 16380-16388
-
-
Doolittle, M.H.1
LeBoeuf, R.C.2
Warden, C.H.3
Bee, L.M.4
Lusis, A.J.5
-
24
-
-
0027279942
-
Atherosclerosis in transgenic mice overexpressing apoliprotein A-II
-
Warden, C.H., Hedrick, C.C., Qiao, J.H., Castellani, L.W. & Lusis, A.J. Atherosclerosis in transgenic mice overexpressing apoliprotein A-II. Science 261, 469-472 (1993).
-
(1993)
Science
, vol.261
, pp. 469-472
-
-
Warden, C.H.1
Hedrick, C.C.2
Qiao, J.H.3
Castellani, L.W.4
Lusis, A.J.5
-
25
-
-
4644219642
-
Haplotype analysis in multiple crosses to identify a QTL gene
-
Wang, X., Korstanje, R., Higgins, D. & Paigen, B. Haplotype analysis in multiple crosses to identify a QTL gene. Genome Res. 14, 1767-1772 (2004).
-
(2004)
Genome Res.
, vol.14
, pp. 1767-1772
-
-
Wang, X.1
Korstanje, R.2
Higgins, D.3
Paigen, B.4
-
26
-
-
33744983522
-
Serum alkaline phosphatase activity is regulated by a chromosomal region containing the alkaline phosphatase 2 gene (Akp2) in C57BL/6J and DBA/2J mice
-
Foreman, J.E. et al. Serum alkaline phosphatase activity is regulated by a chromosomal region containing the alkaline phosphatase 2 gene (Akp2) in C57BL/6J and DBA/2J mice. Physiol. Genomics 23, 295-303 (2005).
-
(2005)
Physiol. Genomics
, vol.23
, pp. 295-303
-
-
Foreman, J.E.1
-
27
-
-
20144386111
-
Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function
-
Chesler, E.J. et al. Complex trait analysis of gene expression uncovers polygenic and pleiotropic networks that modulate nervous system function. Nat. Genet. 37, 233-242 (2005).
-
(2005)
Nat. Genet.
, vol.37
, pp. 233-242
-
-
Chesler, E.J.1
-
28
-
-
22844446947
-
An integrative genomics approach to infer causal associations between gene expression and disease
-
Schadt, E.E. et al. An integrative genomics approach to infer causal associations between gene expression and disease. Nat. Genet. 37, 710-717 (2005).
-
(2005)
Nat. Genet.
, vol.37
, pp. 710-717
-
-
Schadt, E.E.1
-
30
-
-
23244441610
-
Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels
-
Cervino, A.C. et al. Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels. Genomics 86, 505-517 (2005).
-
(2005)
Genomics
, vol.86
, pp. 505-517
-
-
Cervino, A.C.1
-
31
-
-
0037452982
-
Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse
-
Wiltshire, T. et al. Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse. Proc. Natl. Acad. Sci. USA 100, 3380-3385 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3380-3385
-
-
Wiltshire, T.1
-
32
-
-
55449129519
-
Evidence of a large-scale functional organization of mammalian chromosomes
-
Petkov, P.M. et al. Evidence of a large-scale functional organization of mammalian chromosomes. PLoS Genet. 1, e33 (2005).
-
(2005)
PLoS Genet.
, vol.1
-
-
Petkov, P.M.1
-
33
-
-
33645217146
-
Simulating the collaborative cross: Power of QTL detection and mapping resolution in large sets of recombinant inbred strains of mice
-
Valdar, W., Flint, J. & Mott, R. Simulating the collaborative cross: power of QTL detection and mapping resolution in large sets of recombinant inbred strains of mice. Genetics 172, 1783-1797 (2006).
-
(2006)
Genetics
, vol.172
, pp. 1783-1797
-
-
Valdar, W.1
Flint, J.2
Mott, R.3
-
34
-
-
0030068965
-
Confidence intervals in QTL mapping by bootstrapping
-
Visscher, P.M., Thompson, R. & Haley, C.S. Confidence intervals in QTL mapping by bootstrapping. Genetics 143, 1013-1020 (1996).
-
(1996)
Genetics
, vol.143
, pp. 1013-1020
-
-
Visscher, P.M.1
Thompson, R.2
Haley, C.S.3
-
35
-
-
20944448234
-
A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice
-
Toye, A.A. et al. A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice. Diabetologia 48, 675-686 (2005).
-
(2005)
Diabetologia
, vol.48
, pp. 675-686
-
-
Toye, A.A.1
-
36
-
-
0030722279
-
Quantitative trait loci analysis affecting contextual conditioning in mice
-
Caldarone, B. et al. Quantitative trait loci analysis affecting contextual conditioning in mice. Nat. Genet. 17, 335-337 (1997).
-
(1997)
Nat. Genet.
, vol.17
, pp. 335-337
-
-
Caldarone, B.1
-
37
-
-
0030667886
-
Quantitative trait locus analysis of contextual fear conditioning in mice
-
Wehner, J.M. et al. Quantitative trait locus analysis of contextual fear conditioning in mice. Nat. Genet. 17, 331-334 (1997).
-
(1997)
Nat. Genet.
, vol.17
, pp. 331-334
-
-
Wehner, J.M.1
-
38
-
-
21244503060
-
Interacting genetic loci cause airway hyperresponsiveness
-
Ackerman, K.G. et al. Interacting genetic loci cause airway hyperresponsiveness. Physiol. Genomics 21, 105-111 (2005).
-
(2005)
Physiol. Genomics
, vol.21
, pp. 105-111
-
-
Ackerman, K.G.1
-
39
-
-
1842509968
-
QTL Analysis of multiple behavioral measures of anxiety in mice
-
Henderson, N.D., Turri, M.G., DeFries, J.C. & Flint, J. QTL Analysis of multiple behavioral measures of anxiety in mice. Behav. Genet. 34, 267-293 (2004).
-
(2004)
Behav. Genet.
, vol.34
, pp. 267-293
-
-
Henderson, N.D.1
Turri, M.G.2
DeFries, J.C.3
Flint, J.4
-
40
-
-
0034971628
-
Quantitative trait loci affecting the behavior of A/J and CBA/J intercross mice in the elevated plus maze
-
Cohen, R.M., Kang, A. & Gulick, C. Quantitative trait loci affecting the behavior of A/J and CBA/J intercross mice in the elevated plus maze. Mamm. Genome 12, 501-507 (2001).
-
(2001)
Mamm. Genome
, vol.12
, pp. 501-507
-
-
Cohen, R.M.1
Kang, A.2
Gulick, C.3
-
41
-
-
11844280278
-
Genetics of variation in HDL cholesterol in humans and mice
-
Wang, X. & Paigen, B. Genetics of variation in HDL cholesterol in humans and mice. Circ. Res. 96, 27-42 (2005).
-
(2005)
Circ. Res.
, vol.96
, pp. 27-42
-
-
Wang, X.1
Paigen, B.2
-
42
-
-
0030999378
-
Mapping quantitative trait loci for open-field behavior in mice. Behav
-
Gershenfeld, H.K. et al. Mapping quantitative trait loci for open-field behavior in mice. Behav. Genet. 27, 201-210 (1997).
-
(1997)
Genet.
, vol.27
, pp. 201-210
-
-
Gershenfeld, H.K.1
-
43
-
-
15544382002
-
Mapping quantitative trait loci for anxiety in chromosome substitution strains of mice
-
Singer, J.B., Hill, A.E., Nadeau, J.H. & Lander, E.S. Mapping quantitative trait loci for anxiety in chromosome substitution strains of mice. Genetics 169, 855-862 (2005).
-
(2005)
Genetics
, vol.169
, pp. 855-862
-
-
Singer, J.B.1
Hill, A.E.2
Nadeau, J.H.3
Lander, E.S.4
-
44
-
-
0037444633
-
Genetic mapping of variation in spatial learning in the mouse
-
Steinberger, D. et al. Genetic mapping of variation in spatial learning in the mouse. J. Neurosci. 23, 2426-2433 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 2426-2433
-
-
Steinberger, D.1
-
45
-
-
0029088944
-
Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice
-
De Sanctis, G.T. et al. Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice. Nat. Genet. 11, 150-154 (1995).
-
(1995)
Nat. Genet.
, vol.11
, pp. 150-154
-
-
De Sanctis, G.T.1
-
46
-
-
0033791849
-
Quantitative trait loci controlling allergen-induced airway hyperresponsiveness in inbred mice
-
Ewart, S.L. et al. Quantitative trait loci controlling allergen-induced airway hyperresponsiveness in inbred mice. Am. J. Respir. Cell Mol. Biol. 23, 537-545 (2000).
-
(2000)
Am. J. Respir. Cell Mol. Biol.
, vol.23
, pp. 537-545
-
-
Ewart, S.L.1
-
47
-
-
0032787882
-
Quantitative trait loci for growth traits in C57BL/6J x DBA/2J mice
-
Morris, K.H., Ishikawa, A. & Keightley, P.D. Quantitative trait loci for growth traits in C57BL/6J x DBA/2J mice. Mamm. Genome 10, 225-228 (1999).
-
(1999)
Mamm. Genome
, vol.10
, pp. 225-228
-
-
Morris, K.H.1
Ishikawa, A.2
Keightley, P.D.3
-
48
-
-
0031214118
-
Obesity QTLs on mouse chromosomes 2 and 17
-
Taylor, B.A. & Phillips, S.J. Obesity QTLs on mouse chromosomes 2 and 17. Genomics 43, 249-257 (1997).
-
(1997)
Genomics
, vol.43
, pp. 249-257
-
-
Taylor, B.A.1
Phillips, S.J.2
|