Testicular germ cell tumor susceptibility genes from the consomic 129.MOLF-Chr19 mouse strain

Mammalian Genome

Volumn 18, Issue 8, 2007, Pages 584-595

  Zhu, Rui ^a   Ji, Yuan ^a   Xiao, Lianchun ^a   Matin, Angabin ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHROMOSOME; CHROMOSOME 19; CHROMOSOME SUBSTITUTION STRAIN; CONTROLLED STUDY; EMBRYO; GENE IDENTIFICATION; GENE MAPPING; GENETIC ANALYSIS; GENETIC SUSCEPTIBILITY; GENOME ANALYSIS; GERM CELL TUMOR; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PHENOTYPE; TESTIS TUMOR;

ANIMALS; ANIMALS, NEWBORN; CHROMOSOMES, MAMMALIAN; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; MALE; MICE; MICE, INBRED STRAINS; MICRORNAS; MODELS, BIOLOGICAL; NEOPLASMS, GERM CELL AND EMBRYONAL; PEDIGREE; TESTICULAR NEOPLASMS;

EID: 34848921114     PISSN: 09388990     EISSN: 14321777     Source Type: Journal    
DOI: 10.1007/s00335-007-9036-2     Document Type: Article

References (53)

1. Anderson R, Copeland TK, Scholer H, Heasman J, Wylie C (2000) The onset of germ cell migration in the mouse embryo. Mech Dev 91:61-68
2. Antonicka H, Mattman A, Carlson CG, Glerum DM, Hoffbuhr KC, et al. (2003) Mutations in COX15 produce a defect in the mitochondrial heme biosynthetic pathway, causing early-onset fatal hypertrophic cardiomyopathy. Am J Hum Genet 72:101-114
3. Burtis KC, Baker BS (1989) Drosophila doublesex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-specific polypeptides. Cell 56:997-1010
4. Collin GB, Asada Y, Varnum DS, Nadeau JH (1996) DNA pooling as a quick method for finding candidate linkages in multigenic trait analysis: an example involving susceptibility to germ cell tumors. Mamm Genome 7:68-70
5. Crockford GP, Linger R, Hockley S, Dudakia D, Johnson L, et al. (2006) Genome-wide linkage screen for testicular germ cell tumour susceptibility loci. Hum Mol Genet 15:443-451
6. Dieckmann K-P, Skakkebaek NE (1999) Carcinoma in situ of the testis: review of biological and clinical features. Int J Cancer 83:815-822
7. Forman D, Oliver RT, Brett AR, Marsh SG, Moses JH, et al. (1992) Familial testicular cancer: a report of the UK family register, estimation of risk and an HLA class 1 sib-pair analysis. Br J Cancer 65:255-262
8. Glerum DM, Muroff I, Jin C, Tzagoloff A (1997) COX15 codes for a mitochondrial protein essential for the assembly of yeast cytochrome oxidase. J Biol Chem 272:19088-19094
9. Harland SJ, Cook PA, Fossa SD, Horwich A, Mead GM, et al. (1998) Intratubular germ cell neoplasia of the contralateral testis in testicular cancer: defining a high risk group. J Urol 160:1353-1357
10. Heimdal K, Olsson H, Tretli S, Flodgren P, Borresen AL, et al. (1996) Familial testicular cancer in Norway and southern Sweden. Br J Cancer 73:964-969
11. Hemminki K, Li X (2004) Familial risk in testicular cancer as a clue to a heritable and environmental aetiology. Br J Cancer 90:1765-1770
12. Horwich A, Shipley J, Huddart R (2006) Testicular germ-cell cancer. Lancet 367:754-765
13. Ilson DH, Bosl GJ, Motzer R, Dmitrovsky E, Chaganti RSK (1991) Genetic analysis of germ cell tumors: current progress and future prospects. Hematol Oncol Clin North Am 5:1271-1283
14. Jacobsen R, Bostofte E, Engholm G, Hansen J, Olsen JH, et al. (2000) Risk of testicular cancer in men with abnormal semen characteristics: cohort study. BMJ 321:789-792
15. Ju Z, Kapoor M, Newton K, Cheon K, Ramaswamy A, et al. (2005) Global detection of molecular changes reveals concurrent alteration of several biological pathways in nonsmall cell lung cancer cells. Mol Genet Genomics 274:141-154
16. Kawakami T, Zhang C, Okada Y, Okamoto K (2006) Erasure of methylation imprint at the promoter and CTCF-binding site upstream of H19 in human testicular germ cell tumors of adolescents indicate their fetal germ cell origin. Oncogene 25:3225-3236
17. Kehler J, Tolkunova E, Koschorz B, Pesce M, Gentile L, et al. (2004) Oct4 is required for primordial germ cell survival. EMBO J 5:1078-1083
18. Li C, Wong W-H (2001) Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc Natl Acad Sci U S A 98:31-36
19. Looijenga LHJ, Stoop H, de Leeuw HP, de Gouveia Brazao CA, Gillis AJ, et al. (2003) POU5F1 (OCT3/4) identifies cells with pluripotent potential in human germ cell tumors. Cancer Res 63:2244-2250
20. Matin A, Collin GB, Asada Y, Varnum D, Nadeau JH (1999) Susceptibility to testicular germ-cell tumours in a 129.MOLF-Chr 19 chromosome substitution strain. Nat Genet 23:237-240
21. McDonald MT, Flejter W, Sheldon S, Putzi MJ, Gorski JL (1997) XY sex reversal and gonadal dysgenesis due to 9p24 monosomy. Am J Med Genet 73:321-326
22. Molyneaux KA, Wang YC, Schaible K, Wylie C (2004) Transcriptional profiling identifies genes differentially expressed during and after migration in murine primordial germ cells. Gene Exp Patterns 4:167-181
23. Moore FL, Jaruzelska J, Fox MS, Urano J, Firpo MT, et al. (2003) Human pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins. Proc Natl Acad Sci U S A 100:538-543
24. Muroya K, Okuyama T, Goishi K, Ogiso Y, Fukuda S, et al. (2000) Sex-determining gene(s) on distal 9p: clinical and molecular studies in six cases. J Clin Endocr Metab 85:3094-3100
25. Oosterhuis JW, Looijenga LHJ (2005) Testicular germ-cell tumours in a broader perspective. Nat Rev Cancer 5:210-222
26. Pesce M, Gross MK, Scholer HR (1998) In line with our ancestors: Oct-4 and the mammalian germ. Bioessays 20:722-732
27. Rapley EA, Crockford GP, Teare D, Biggs P, Seal S, et al. (2000) Localization to Xq27 of a susceptibility gene for testicular germ-cell tumors. Nat Genet 24:197-200
28. Raymond CS, Shamu CE, Shen MM, Seifert KJ, Hirsch B, et al. (1998) Evidence for evolutionary conservation of sex-determining genes. Nature 391:691-695
29. Raymond CS, Parker ED, Kettlewell JR, Brown LG, Page DC, et al. (1999) A region of human chromosome 9p required for testis development contains two genes related to known sexual regulators. Hum Mol Genet 8:989-996
30. Rescorla FJ (1999) Pediatric germ cell tumors. Semin Surg Oncol 16:144-158
31. Roldo C, Missiaglia E, Hagan JP, Falconi M, Capelli P, et al. (2006) MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathological features and clinical behaviour. J Clin Oncol 24:4677-4684
32. Ross J (1995) mRNA stability in mammalian cells. Microbiol Rev 59:423-450
33. Scholer HR, Dressler GR, Balling R, Rohdewohld H, Gruss P (1990) Oct-4: a germline-specific transcription factor mapping to the mouse t-complex. EMBO J 9:2185-2195
34. Shan Z, Zabel B, Trautmann U, Hillig U, Ottolenghi C, et al. (2000) FISH mapping of the sex-reversal region on human chromosome 9p in two XY females and in primates. Eur J Hum Genet 8:167-173
35. Shen MM, Hodgkin J (1988) Mab-3, a gene required for sex-specific yolk protein expression and a male-specific lineage in C. elegans. Cell 54:1019-1031
36. Silver LM (1995) Mouse genetics: concepts and applications (New York: Oxford University Press)
37. Skakkebaek NE, Berthelsen JG, Giwercman A, Muller J (1987) Carcinoma-in-situ of the testis: possible origin from gonocytes and precursor of all types of germ cell tumours except spermatocytoma. Int J Androl 10:19-28
38. Skakkebaek NE, Holm M, Hoei-Hansen C, Jorgensen N, Rajpert-De Meyts E (2003) Association between testicular dysgenesis syndrome (TDS) and testicular neoplasia: evidence from 20 adult patients with signs of maldevelopment of the testis. APMIS 111:1-11
39. Smiraglia DJ, Szymanska J, Kraggerud SM, Lothe RA, Peltomaki P, et al. (2002) Distinct epigenetic phenotypes in seminomatous and nonseminomatous testicular germ cell tumors. Oncogene 21:3909-3916
40. Smith CA, McClive PJ, Western PS, Reed KJ, Sinclair AH (1999) Conservation of a sex-determining gene. Nature 402:601-602
41. Stevens LC (1966) Development of resistance to teratocarcinogeneis by primordial germ cells in mice. J Natl Cancer Inst 37:859-867
42. Stevens LC (1967) Origin of testicular teratomas from primordial germ cells in mice. J Natl Cancer Inst 38:549-552
43. Stevens LC (1970) Experimental production of testicular teratomas in mice of strains 129, A/He, and their F1 hybrids. J Natl Cancer Inst 44:923-929
44. Stevens LC (1973a) A developmental genetic approach to the study of teratocarcinogenesis. BioScience 23:169-172
45. Stevens LC (1973b) A new inbred subline of mice (129/terSv) with a high incidence of spontaneous congenital testicular teratomas. J Natl Cancer Inst 50:235-242
46. Stevens LC, Hummel KP (1957) A description of spontaneous congenital testicular teratomas in strain 129 mice. J Natl Cancer Inst 18:719-747
47. Tollerud DJ, Blattner WA, Fraser MC, Brown LM, Pottern L, et al. (1985) Familial testicular cancer and urogenital developmental anomalies. Cancer 55:1849-1854
48. Veitia R, Nunes M, Brauner R, Doco-Fenzy M, Joanny-Flinois O, et al. (1997) Deletions of distal 9p associated with 46,XY male to female sex reversal: definition of the breakpoints at 9p23.3-p24.1. Genomics 41:271-274
49. Voorhoeve PM, le Sage C, Schrier M, Gillis AJM, Stoop H, et al. (2006) A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell 124:1169-1181
50. Wrehlke C, Wiedemeyer WR, Schmitt-Wrede HP, Mincheva A, Lichter P, et al. (1999) Genomic organization of mouse gene zfp162. DNA Cell Biol 18:419-428
51. Yeom YI, Fuhrmann G, Ovitt CE, Brehm A, Ohbo K, et al. (1996) Germline regulatory element of Oct-4 specific for the totipotent cycle of embryonal cells. Development 122:881-894
52. Youngren KK, Nadeau JH, Matin A (2003) Testicular cancer susceptibility in the 129.MOLF-Chr 19 mouse strain: additive effects, gene interactions and epigenetic modifications. Hum Mol Genet 12:389-398
53. Youngren KK, Coveney D, Peng X, Bhattacharya C, Schmidt LS, et al. (2005) The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours. Nature 435:360-364