Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability

PLoS Genetics

Volumn 7, Issue 7, 2011, Pages

  Sanna, Serena ^a   Li, Bingshan ^b   Mulas, Antonella ^a   Sidore, Carlo ^a,b,c   Kang, Hyun M ^b   Jackson, Anne U ^b   Piras, Maria Grazia ^a   Usala, Gianluca ^a   Maninchedda, Giuseppe ^d   Sassu, Alessandro ^d   Serra, Fabrizio ^d   Palmas, Maria Antonietta ^d   Wood III, William H ^e   Njølstad, Inger ^f   Laakso, Markku ^g   Hveem, Kristian ^h   Tuomilehto, Jaakko ^i,j,k   Lakka, Timo A ^g   Rauramaa, Rainer ^g   Boehnke, Michael ^b   Cucca, Francesco ^a,c   Uda, Manuela ^a   Schlessinger, David ^e   Nagaraja, Ramaiah ^e   Abecasis, Gonçalo R ^b   more..

^a Milan Unit   (Italy)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF SASSARI   (Italy)

^d Shardna Life Sciences ^*  (Italy)

^e NATIONAL INSTITUTE ON AGING   (United States)

^f UNIVERSITY OF TROMSØ   (Norway)

^g UNIVERSITY OF EASTERN FINLAND   (Finland)

^h NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

ⁱ NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^j UNIVERSITY OF HELSINKI   (Finland)

^k SOUTH OSTROBOTHNIA CENTRAL HOSPITAL   (Finland)

more..

Author keywords

[No Author keywords available]

Indexed keywords

LOW DENSITY LIPOPROTEIN CHOLESTEROL;

APOB GENE; APOC1 GENE; APOC2 GENE; APOE GENE; ARTICLE; CONTROLLED STUDY; FINLAND; GENE; GENE IDENTIFICATION; GENE MAPPING; GENE STRUCTURE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HERITABILITY; HUMAN; ITALY; LDLR GENE; NORWAY; PCSK9 GENE; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SORT1 GENE; CAUCASIAN; CHROMOSOME MAP; GENE LOCUS; GENETIC PREDISPOSITION; GENETICS; SINGLE NUCLEOTIDE POLYMORPHISM;

CHOLESTEROL, LDL; CHROMOSOME MAPPING; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; ITALY; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 79960943621     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002198     Document Type: Article

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