-
1
-
-
77955499945
-
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus
-
Musunuru, K. et al. From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature 466, 714-719 (2010).
-
(2010)
Nature
, vol.466
, pp. 714-719
-
-
Musunuru, K.1
-
2
-
-
61349113311
-
Systems genetics of complex traits in Drosophila melanogaster
-
Ayroles, J. F. et al. Systems genetics of complex traits in Drosophila melanogaster. Nature Genet. 41, 299-307 (2009).
-
(2009)
Nature Genet.
, vol.41
, pp. 299-307
-
-
Ayroles, J.F.1
-
4
-
-
84866848293
-
Epistasis dominates the genetic architecture of Drosophila quantitative traits
-
Huang, W. et al. Epistasis dominates the genetic architecture of Drosophila quantitative traits. Proc. Natl Acad. Sci. USA 109, 15553-15559 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 15553-15559
-
-
Huang, W.1
-
6
-
-
84866919001
-
Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions
-
Wu, C. et al. Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions. Nature Genet. 44, 1090-1097 (2012).
-
(2012)
Nature Genet.
, vol.44
, pp. 1090-1097
-
-
Wu, C.1
-
7
-
-
84861122792
-
-
(ed. Waddington, C. H.) (Edinburgh Univ. Press)
-
Burns, J. in Towards a Theoretical Biology Vol. 3 (ed. Waddington, C. H.) 47-51 (Edinburgh Univ. Press, 1970).
-
(1970)
Towards A Theoretical Biology
, vol.3
, pp. 47-51
-
-
Burns, J.1
-
9
-
-
33846641686
-
Quantitative trait transcripts for nicotine resistance in Drosophila melanogaster
-
DOI 10.1038/ng1944, PII NG1944
-
Passador-Gurgel, G., Hsieh, W. P., Hunt, P., Deighton, N. & Gibson, G. Quantitative trait transcripts for nicotine resistance in Drosophila melanogaster. Nature Genet. 39, 264-268 (2007). (Pubitemid 46184360)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 264-268
-
-
Passador-Gurgel, G.1
Hsieh, W.-P.2
Hunt, P.3
Deighton, N.4
Gibson, G.5
-
10
-
-
42649125570
-
Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass
-
DOI 10.1038/ng.134, PII NG134
-
Petretto, E. et al. Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass. Nature Genet. 40, 546-552 (2008). (Pubitemid 351601220)
-
(2008)
Nature Genetics
, vol.40
, Issue.5
, pp. 546-552
-
-
Petretto, E.1
Sarwar, R.2
Grieve, I.3
Lu, H.4
Kumaran, M.K.5
Muckett, P.J.6
Mangion, J.7
Schroen, B.8
Benson, M.9
Punjabi, P.P.10
Prasad, S.K.11
Pennell, D.J.12
Kiesewetter, C.13
Tasheva, E.S.14
Corpuz, L.M.15
Webb, M.D.16
Conrad, G.W.17
Kurtz, T.W.18
Kren, V.19
Fischer, J.20
Hubner, N.21
Pinto, Y.M.22
Pravenec, M.23
Aitman, T.J.24
Cook, S.A.25
more..
-
11
-
-
0032958470
-
Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats
-
DOI 10.1038/5013
-
Aitman, T. J. et al. Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats. Nature Genet. 21, 76-83 (1999). (Pubitemid 29036288)
-
(1999)
Nature Genetics
, vol.21
, Issue.1
, pp. 76-83
-
-
Aitman, T.J.1
Glazier, A.M.2
Wallace, C.A.3
Cooper, L.D.4
Norsworthy, P.J.5
Wahid, F.N.6
Al-Majali, K.M.7
Trembling, P.M.8
Mann, C.J.9
Shoulders, C.C.10
Graf, D.11
St. Lezin, E.12
Kurtz, T.W.13
Kren, V.14
Pravenec, M.15
Ibrahimi, A.16
Abumrad, N.A.17
Stanton, L.W.18
Scott, J.19
-
12
-
-
22844446947
-
An integrative genomics approach to infer causal associations between gene expression and disease
-
DOI 10.1038/ng1589
-
Schadt, E. E. et al. An integrative genomics approach to infer causal associations between gene expression and disease. Nature Genet. 37, 710-717 (2005). (Pubitemid 41754887)
-
(2005)
Nature Genetics
, vol.37
, Issue.7
, pp. 710-717
-
-
Schadt, E.E.1
Lamb, J.2
Yang, X.3
Zhu, J.4
Edwards, S.5
Thakurta, D.G.6
Sieberts, S.K.7
Monks, S.8
Reitman, M.9
Zhang, C.10
Lum, P.Y.11
Leonardson, A.12
Thieringer, R.13
Metzger, J.M.14
Yang, L.15
Castle, J.16
Zhu, H.17
Kash, S.F.18
Drake, T.A.19
Sachs, A.20
Lusis, A.J.21
more..
-
13
-
-
84859240600
-
Genetic architecture of highly complex chemical resistance traits across four yeast strains
-
Ehrenreich, I. M. et al. Genetic architecture of highly complex chemical resistance traits across four yeast strains. PLoS Genet. 8, e1002570 (2012).
-
(2012)
PLoS Genet.
, vol.8
-
-
Ehrenreich, I.M.1
-
14
-
-
0037177625
-
Genetic dissection of transcriptional regulation in budding yeast
-
DOI 10.1126/science.1069516
-
Brem, R. B., Yvert, G., Clinton, R. & Kruglyak, L. Genetic dissection of transcriptional regulation in budding yeast. Science 296, 752-755 (2002). (Pubitemid 34442007)
-
(2002)
Science
, vol.296
, Issue.5568
, pp. 752-755
-
-
Brem, R.B.1
Yvert, G.2
Clinton, R.3
Kruglyak, L.4
-
15
-
-
13444306165
-
The landscape of genetic complexity across 5,700 gene expression traits in yeast
-
DOI 10.1073/pnas.0408709102
-
Brem, R. B. & Kruglyak, L. The landscape of genetic complexity across 5,700 gene expression traits in yeast. Proc. Natl Acad. Sci. USA 102, 1572-1577 (2005). (Pubitemid 40209209)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.5
, pp. 1572-1577
-
-
Brem, R.B.1
Kruglyak, L.2
-
16
-
-
75649122259
-
A high-resolution association mapping panel for the dissection of complex traits in mice
-
Bennett, B. J. et al. A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Res. 20, 281-290 (2010).
-
(2010)
Genome Res.
, vol.20
, pp. 281-290
-
-
Bennett, B.J.1
-
17
-
-
84885645853
-
Transcriptome and genome sequencing uncovers functional variation in humans
-
Lappalainen, T. et al. Transcriptome and genome sequencing uncovers functional variation in humans. Nature 501, 506-511 (2013).
-
(2013)
Nature
, vol.501
, pp. 506-511
-
-
Lappalainen, T.1
-
18
-
-
77957915239
-
Expression quantitative trait loci: Replication, tissue- and sex-specificity in mice
-
van Nas, A. et al. Expression quantitative trait loci: replication, tissue- and sex-specificity in mice. Genetics 185, 1059-1068 (2010).
-
(2010)
Genetics
, vol.185
, pp. 1059-1068
-
-
Van Nas, A.1
-
19
-
-
55449096399
-
Genetical genomics: Spotlight on QTL hotspots
-
Breitling, R. et al. Genetical genomics: spotlight on QTL hotspots. PLoS Genet. 4, e1000232 (2008).
-
(2008)
PLoS Genet.
, vol.4
-
-
Breitling, R.1
-
20
-
-
84868036620
-
Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages
-
Orozco, L. D. et al. Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages. Cell 151, 658-670 (2012).
-
(2012)
Cell
, vol.151
, pp. 658-670
-
-
Orozco, L.D.1
-
21
-
-
77649236340
-
Systems genetics analysis of gene-by-environment interactions in human cells
-
Romanoski, C. E. et al. Systems genetics analysis of gene-by-environment interactions in human cells. Am. J. Hum. Genet. 86, 399-410 (2010).
-
(2010)
Am. J. Hum. Genet.
, vol.86
, pp. 399-410
-
-
Romanoski, C.E.1
-
22
-
-
84865777825
-
Linking disease associations with regulatory information in the human genome
-
Schaub, M. A., Boyle, A. P., Kundaje, A., Batzoglou, S. & Snyder, M. Linking disease associations with regulatory information in the human genome. Genome Res. 22, 1748-1759 (2012).
-
(2012)
Genome Res.
, vol.22
, pp. 1748-1759
-
-
Schaub, M.A.1
Boyle, A.P.2
Kundaje, A.3
Batzoglou, S.4
Snyder, M.5
-
23
-
-
84880254076
-
Genetic regulation of human adipose microRNA expression and its consequences for metabolic traits
-
Civelek, M. et al. Genetic regulation of human adipose microRNA expression and its consequences for metabolic traits. Hum. Mol. Genet. 22, 3023-3037 (2013).
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 3023-3037
-
-
Civelek, M.1
-
24
-
-
84873489136
-
Human disease-associated genetic variation impacts large intergenic non-coding RNA expression
-
Kumar, V. et al. Human disease-associated genetic variation impacts large intergenic non-coding RNA expression. PLoS Genet. 9, e1003201 (2013).
-
(2013)
PLoS Genet.
, vol.9
-
-
Kumar, V.1
-
25
-
-
79959812980
-
Comparative analysis of proteome and transcriptome variation in mouse
-
Ghazalpour, A. et al. Comparative analysis of proteome and transcriptome variation in mouse. PLoS Genet. 7, e1001393 (2011).
-
(2011)
PLoS Genet.
, vol.7
-
-
Ghazalpour, A.1
-
26
-
-
50649089207
-
RNA-seq: An assessment of technical reproducibility and comparison with gene expression arrays
-
Marioni, J. C., Mason, C. E., Mane, S. M., Stephens, M. & Gilad, Y. RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays. Genome Res. 18, 1509-1517 (2008).
-
(2008)
Genome Res.
, vol.18
, pp. 1509-1517
-
-
Marioni, J.C.1
Mason, C.E.2
Mane, S.M.3
Stephens, M.4
Gilad, Y.5
-
27
-
-
77955489278
-
Genetic validation of whole-transcriptome sequencing for mapping expression affected by cis-regulatory variation
-
Babak, T. et al. Genetic validation of whole-transcriptome sequencing for mapping expression affected by cis-regulatory variation. BMC Genomics 11, 473 (2010).
-
(2010)
BMC Genomics
, vol.11
, pp. 473
-
-
Babak, T.1
-
28
-
-
84871601885
-
Powerful identification of cis-regulatory SNPs in human primary monocytes using allele-specific gene expression
-
Almlof, J. C. et al. Powerful identification of cis-regulatory SNPs in human primary monocytes using allele-specific gene expression. PLoS ONE 7, e52260 (2012).
-
(2012)
PLoS ONE
, vol.7
-
-
Almlof, J.C.1
-
29
-
-
84887098883
-
Analysis of allele specific expression in mouse liver by RNA-seq: A comparison with cis-eQTL identified using genetic linkage
-
Lagarrigue, S. et al. Analysis of allele specific expression in mouse liver by RNA-seq: a comparison with cis-eQTL identified using genetic linkage. Genetics 195,1157-1166 (2013).
-
(2013)
Genetics
, vol.195
, pp. 1157-1166
-
-
Lagarrigue, S.1
-
30
-
-
84857111200
-
DNase i sensitivity QTLs are a major determinant of human expression variation
-
Degner, J. F. et al. DNase I sensitivity QTLs are a major determinant of human expression variation. Nature 482, 390-394 (2012).
-
(2012)
Nature
, vol.482
, pp. 390-394
-
-
Degner, J.F.1
-
31
-
-
79960688508
-
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
-
Bell, J. T. et al. DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines. Genome Biol. 12, R10 (2011).
-
(2011)
Genome Biol.
, vol.12
-
-
Bell, J.T.1
-
32
-
-
84856321864
-
Dissecting the regulatory architecture of gene expression QTLs
-
Gaffney, D. J. et al. Dissecting the regulatory architecture of gene expression QTLs. Genome Biol. 13, R7 (2012).
-
(2012)
Genome Biol.
, vol.13
-
-
Gaffney, D.J.1
-
33
-
-
84866361701
-
Circuitry and dynamics of human transcription factor regulatory networks
-
Neph, S. et al. Circuitry and dynamics of human transcription factor regulatory networks. Cell 150, 1274-1286 (2012).
-
(2012)
Cell
, vol.150
, pp. 1274-1286
-
-
Neph, S.1
-
34
-
-
84888641656
-
Effect of natural genetic variation on enhancer selection and function
-
Heinz, S. et al. Effect of natural genetic variation on enhancer selection and function. Nature http://dx.doi.org/10.1038/nature12615 (2013).
-
(2013)
Nature
-
-
Heinz, S.1
-
35
-
-
84887320760
-
Extensive variation in chromatin states across humans
-
Kasowski, M. et al. Extensive variation in chromatin states across humans. Science 342, 750-752 (2013).
-
(2013)
Science
, vol.342
, pp. 750-752
-
-
Kasowski, M.1
-
36
-
-
84887320563
-
Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription
-
Kilpinen, H. et al. Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription. Science 342, 744-747 (2013).
-
(2013)
Science
, vol.342
, pp. 744-747
-
-
Kilpinen, H.1
-
37
-
-
84887322043
-
Identification of genetic variants that affect histone modifications in human cells
-
McVicker, G. et al. Identification of genetic variants that affect histone modifications in human cells. Science 342, 747-749 (2013).
-
(2013)
Science
, vol.342
, pp. 747-749
-
-
McVicker, G.1
-
38
-
-
35648969195
-
Genetic basis of proteome variation in yeast
-
DOI 10.1038/ng.2007.22, PII NG200722
-
Foss, E. J. et al. Genetic basis of proteome variation in yeast. Nature Genet. 39, 1369-1375 (2007). (Pubitemid 350035001)
-
(2007)
Nature Genetics
, vol.39
, Issue.11
, pp. 1369-1375
-
-
Foss, E.J.1
Radulovic, D.2
Shaffer, S.A.3
Ruderfer, D.M.4
Bedalov, A.5
Goodlett, D.R.6
Kruglyak, L.7
-
39
-
-
84876381289
-
Quantitative trait loci mapping of the mouse plasma proteome (pQTL)
-
Holdt, L. M. et al. Quantitative trait loci mapping of the mouse plasma proteome (pQTL). Genetics 193, 601-608 (2013).
-
(2013)
Genetics
, vol.193
, pp. 601-608
-
-
Holdt, L.M.1
-
40
-
-
84865083411
-
Identification of cis-regulatory variation influencing protein abundance levels in human plasma
-
Lourdusamy, A. et al. Identification of cis-regulatory variation influencing protein abundance levels in human plasma. Hum. Mol. Genet. 21, 3719-3726 (2012).
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 3719-3726
-
-
Lourdusamy, A.1
-
41
-
-
44949201115
-
A genome-wide association study identifies protein quantitative trait loci (pQTLs)
-
Melzer, D. et al. A genome-wide association study identifies protein quantitative trait loci (pQTLs). PLoS Genet. 4, e1000072 (2008).
-
(2008)
PLoS Genet.
, vol.4
-
-
Melzer, D.1
-
42
-
-
84879879014
-
Variation and genetic control of protein abundance in humans
-
Wu, L. et al. Variation and genetic control of protein abundance in humans. Nature 499, 79-82 (2013).
-
(2013)
Nature
, vol.499
, pp. 79-82
-
-
Wu, L.1
-
44
-
-
84858790233
-
Innovation: Metabolomics: The apogee of the omics trilogy
-
Patti, G. J., Yanes, O. & Siuzdak, G. Innovation: Metabolomics: the apogee of the omics trilogy. Nature Rev. Mol. Cell Biol. 13, 263-269 (2012).
-
(2012)
Nature Rev. Mol. Cell Biol.
, vol.13
, pp. 263-269
-
-
Patti, G.J.1
Yanes, O.2
Siuzdak, G.3
-
45
-
-
84886847758
-
A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use
-
Liu, S. et al. A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid use. Nature 502, 550-554 (2013).
-
(2013)
Nature
, vol.502
, pp. 550-554
-
-
Liu, S.1
-
46
-
-
57149114936
-
Genetics meets metabolomics: A genome-wide association study of metabolite profiles in human serum
-
Gieger, C. et al. Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PLoS Genet. 4, e1000282 (2008).
-
(2008)
PLoS Genet.
, vol.4
-
-
Gieger, C.1
-
47
-
-
84857648463
-
Genome-wide association study identifies multiple loci influencing human serum metabolite levels
-
Kettunen, J. et al. Genome-wide association study identifies multiple loci influencing human serum metabolite levels. Nature Genet. 44, 269-276 (2012).
-
(2012)
Nature Genet.
, vol.44
, pp. 269-276
-
-
Kettunen, J.1
-
48
-
-
80052398214
-
Human metabolic individuality in biomedical and pharmaceutical research
-
Suhre, K. et al. Human metabolic individuality in biomedical and pharmaceutical research. Nature 477, 54-60 (2011).
-
(2011)
Nature
, vol.477
, pp. 54-60
-
-
Suhre, K.1
-
49
-
-
66049159816
-
Genetic architecture of quantitative traits in mice, flies, and humans
-
Flint, J. & Mackay, T. F. Genetic architecture of quantitative traits in mice, flies, and humans. Genome Res. 19, 723-733 (2009).
-
(2009)
Genome Res.
, vol.19
, pp. 723-733
-
-
Flint, J.1
MacKay, T.F.2
-
50
-
-
79951536701
-
Mapping the epistatic network underlying murine reproductive fatpad variation
-
Jarvis, J. P. & Cheverud, J. M. Mapping the epistatic network underlying murine reproductive fatpad variation. Genetics 187, 597-610 (2011).
-
(2011)
Genetics
, vol.187
, pp. 597-610
-
-
Jarvis, J.P.1
Cheverud, J.M.2
-
51
-
-
58149396842
-
Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis
-
Shao, H. et al. Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis. Proc. Natl Acad. Sci. USA 105, 19910-19914 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 19910-19914
-
-
Shao, H.1
-
52
-
-
0036851837
-
Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor
-
DOI 10.1038/nm789
-
Naya, F. J. et al. Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor. Nature Med. 8, 1303-1309 (2002). (Pubitemid 35373564)
-
(2002)
Nature Medicine
, vol.8
, Issue.11
, pp. 1303-1309
-
-
Naya, F.J.1
Black, B.L.2
Wu, H.3
Bassel-Duby, R.4
Richardson, J.A.5
Hill, J.A.6
Olson, E.N.7
-
53
-
-
84864884509
-
Good enough solutions and the genetics of complex diseases
-
Weiss, J. N. et al. "Good enough solutions" and the genetics of complex diseases. Circ. Res. 111, 493-504 (2012).
-
(2012)
Circ. Res.
, vol.111
, pp. 493-504
-
-
Weiss, J.N.1
-
54
-
-
84856405512
-
The mystery of missing heritability: Genetic interactions create phantom heritability
-
Zuk, O., Hechter, E., Sunyaev, S. R. & Lander, E. S. The mystery of missing heritability: genetic interactions create phantom heritability. Proc. Natl Acad. Sci. USA 109, 1193-1198 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 1193-1198
-
-
Zuk, O.1
Hechter, E.2
Sunyaev, S.R.3
Lander, E.S.4
-
55
-
-
84868312363
-
Ultrafast genome-wide scan for SNP-SNP interactions in common complex disease
-
Prabhu, S. & Pe'er, I. Ultrafast genome-wide scan for SNP-SNP interactions in common complex disease. Genome Res. 22, 2230-2240 (2012).
-
(2012)
Genome Res.
, vol.22
, pp. 2230-2240
-
-
Prabhu, S.1
Pe'er, I.2
-
56
-
-
40149087235
-
Data and theory point to mainly additive genetic variance for complex traits
-
Hill, W. G., Goddard, M. E. & Visscher, P. M. Data and theory point to mainly additive genetic variance for complex traits. PLoS Genet. 4, e1000008 (2008).
-
(2008)
PLoS Genet.
, vol.4
-
-
Hill, W.G.1
Goddard, M.E.2
Visscher, P.M.3
-
57
-
-
84873722165
-
Finding the sources of missing heritability in a yeast cross
-
Bloom, J. S., Ehrenreich, I. M., Loo, W. T., Lite, T. L. & Kruglyak, L. Finding the sources of missing heritability in a yeast cross. Nature 494, 234-237 (2013).
-
(2013)
Nature
, vol.494
, pp. 234-237
-
-
Bloom, J.S.1
Ehrenreich, I.M.2
Loo, W.T.3
Lite, T.L.4
Kruglyak, L.5
-
58
-
-
84872156123
-
Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice
-
Parks, B. W. et al. Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice. Cell. Metab. 17, 141-152 (2013).
-
(2013)
Cell. Metab.
, vol.17
, pp. 141-152
-
-
Parks, B.W.1
-
59
-
-
43249129715
-
Gene-environment interaction in yeast gene expression
-
Smith, E. N. & Kruglyak, L. Gene-environment interaction in yeast gene expression. PLoS Biol. 6, e83 (2008).
-
(2008)
PLoS Biol.
, vol.6
-
-
Smith, E.N.1
Kruglyak, L.2
-
60
-
-
65249170333
-
Genetic analysis of radiation-induced changes in human gene expression
-
Smirnov, D. A., Morley, M., Shin, E., Spielman, R. S. & Cheung, V. G. Genetic analysis of radiation-induced changes in human gene expression. Nature 459, 587-591 (2009).
-
(2009)
Nature
, vol.459
, pp. 587-591
-
-
Smirnov, D.A.1
Morley, M.2
Shin, E.3
Spielman, R.S.4
Cheung, V.G.5
-
61
-
-
59149100506
-
System-wide molecular evidence for phenotypic buffering in Arabidopsis
-
Fu, J. et al. System-wide molecular evidence for phenotypic buffering in Arabidopsis. Nature Genet. 41, 166-167 (2009).
-
(2009)
Nature Genet.
, vol.41
, pp. 166-167
-
-
Fu, J.1
-
62
-
-
45149106353
-
Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks
-
DOI 10.1038/ng.167, PII NG167
-
Zhu, J. et al. Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks. Nature Genet. 40, 854-861 (2008). (Pubitemid 351913653)
-
(2008)
Nature Genetics
, vol.40
, Issue.7
, pp. 854-861
-
-
Zhu, J.1
Zhang, B.2
Smith, E.N.3
Drees, B.4
Brem, R.B.5
Kruglyak, L.6
Bumgarner, R.E.7
Schadt, E.E.8
-
63
-
-
70349349170
-
-
(Cambridge Univ. Press)
-
Pearl, J. Causality (Cambridge Univ. Press, 2009).
-
(2009)
Causality
-
-
Pearl, J.1
-
64
-
-
84870066616
-
A systematic approach to multifactorial cardiovascular disease: Causal analysis
-
Schwartz, S. M., Schwartz, H. T., Horvath, S., Schadt, E. & Lee, S. I. A systematic approach to multifactorial cardiovascular disease: causal analysis. Arterioscler Thromb. Vasc. Biol. 32, 2821-2835 (2013).
-
(2013)
Arterioscler Thromb. Vasc. Biol.
, vol.32
, pp. 2821-2835
-
-
Schwartz, S.M.1
Schwartz, H.T.2
Horvath, S.3
Schadt, E.4
Lee, S.I.5
-
66
-
-
84870305264
-
Wisdom of crowds for robust gene network inference
-
Marbach, D. et al. Wisdom of crowds for robust gene network inference. Nature Methods 9, 796-804 (2012).
-
(2012)
Nature Methods
, vol.9
, pp. 796-804
-
-
Marbach, D.1
-
67
-
-
84879121298
-
A systems biology framework identifies molecular underpinnings of coronary heart disease
-
Huan, T. et al. A systems biology framework identifies molecular underpinnings of coronary heart disease. Arterioscler Thromb. Vasc. Biol. (2013).
-
(2013)
Arterioscler Thromb. Vasc. Biol.
-
-
Huan, T.1
-
68
-
-
84876907931
-
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease
-
Zhang, B. et al. Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease. Cell 153, 707-720 (2013).
-
(2013)
Cell
, vol.153
, pp. 707-720
-
-
Zhang, B.1
-
69
-
-
77957126059
-
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk
-
Heinig, M. et al. A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature 467, 460-464 (2010).
-
(2010)
Nature
, vol.467
, pp. 460-464
-
-
Heinig, M.1
-
70
-
-
79955455061
-
A Bayesian framework for inference of the genotype-phenotype map for segregating populations
-
Hageman, R. S., Leduc, M. S., Korstanje, R., Paigen, B. & Churchill, G. A. A Bayesian framework for inference of the genotype-phenotype map for segregating populations. Genetics 187, 1163-1170 (2011).
-
(2011)
Genetics
, vol.187
, pp. 1163-1170
-
-
Hageman, R.S.1
Leduc, M.S.2
Korstanje, R.3
Paigen, B.4
Churchill, G.A.5
-
71
-
-
84876452797
-
Modeling causality for pairs of phenotypes in system genetics
-
Neto, E. C. et al. Modeling causality for pairs of phenotypes in system genetics. Genetics 193, 1003-1013 (2013).
-
(2013)
Genetics
, vol.193
, pp. 1003-1013
-
-
Neto, E.C.1
-
73
-
-
78549270383
-
Critical reasoning on causal inference in genome-wide linkage and association studies
-
Li, Y., Tesson, B. M., Churchill, G. A. & Jansen, R. C. Critical reasoning on causal inference in genome-wide linkage and association studies. Trends Genet. 26, 493-498 (2010).
-
(2010)
Trends Genet.
, vol.26
, pp. 493-498
-
-
Li, Y.1
Tesson, B.M.2
Churchill, G.A.3
Jansen, R.C.4
-
74
-
-
49849090353
-
Inferring causal phenotype networks from segregating populations
-
Chaibub Neto, E., Ferrara, C. T., Attie, A. D. & Yandell, B. S. Inferring causal phenotype networks from segregating populations. Genetics 179, 1089-1100 (2008).
-
(2008)
Genetics
, vol.179
, pp. 1089-1100
-
-
Chaibub Neto, E.1
Ferrara, C.T.2
Attie, A.D.3
Yandell, B.S.4
-
75
-
-
33746623411
-
Structural model analysis of multiple quantitative traits
-
Li, R. et al. Structural model analysis of multiple quantitative traits. PLoS Genet. 2, e114 (2006).
-
(2006)
PLoS Genet.
, vol.2
-
-
Li, R.1
-
76
-
-
84858779229
-
HaploReg: A resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
-
Ward, L. D. & Kellis, M. HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants. Nucleic Acids Res. 40, D930-D934 (2012).
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Ward, L.D.1
Kellis, M.2
-
77
-
-
84865712382
-
Annotation of functional variation in personal genomes using RegulomeDB
-
Boyle, A. P. et al. Annotation of functional variation in personal genomes using RegulomeDB. Genome Res. 22, 1790-1797 (2012).
-
(2012)
Genome Res.
, vol.22
, pp. 1790-1797
-
-
Boyle, A.P.1
-
78
-
-
84874189972
-
Genotype to phenotype: Lessons from model organisms for human genetics
-
Lehner, B. Genotype to phenotype: lessons from model organisms for human genetics. Nature Rev. Genet. 14, 168-178 (2013).
-
(2013)
Nature Rev. Genet.
, vol.14
, pp. 168-178
-
-
Lehner, B.1
-
79
-
-
75649111192
-
The genetic landscape of a cell
-
Costanzo, M. et al. The genetic landscape of a cell. Science 327, 425-431 (2010).
-
(2010)
Science
, vol.327
, pp. 425-431
-
-
Costanzo, M.1
-
80
-
-
73349095048
-
Systematic mapping of genetic interaction networks
-
Dixon, S. J., Costanzo, M., Baryshnikova, A., Andrews, B. & Boone, C. Systematic mapping of genetic interaction networks. Annu. Rev. Genet. 43, 601-625 (2009).
-
(2009)
Annu. Rev. Genet.
, vol.43
, pp. 601-625
-
-
Dixon, S.J.1
Costanzo, M.2
Baryshnikova, A.3
Andrews, B.4
Boone, C.5
-
81
-
-
57149114316
-
Genetic analysis of human traits in vitro: Drug response and gene expression in lymphoblastoid cell lines
-
Choy, E. et al. Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines. PLoS Genet. 4, e1000287 (2008).
-
(2008)
PLoS Genet.
, vol.4
-
-
Choy, E.1
-
82
-
-
79957607662
-
Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes
-
Small, K. S. et al. Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes. Nature Genet. 43, 561-564 (2011).
-
(2011)
Nature Genet.
, vol.43
, pp. 561-564
-
-
Small, K.S.1
-
83
-
-
60149091657
-
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
-
Sreekumar, A. et al. Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature 457, 910-914 (2009).
-
(2009)
Nature
, vol.457
, pp. 910-914
-
-
Sreekumar, A.1
-
84
-
-
79953733693
-
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
-
Wang, Z. et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature 472, 57-63 (2011).
-
(2011)
Nature
, vol.472
, pp. 57-63
-
-
Wang, Z.1
-
85
-
-
79953737332
-
Metabolite profiles and the risk of developing diabetes
-
Wang, T. J. et al. Metabolite profiles and the risk of developing diabetes. Nature Med. 17, 448-453 (2011).
-
(2011)
Nature Med.
, vol.17
, pp. 448-453
-
-
Wang, T.J.1
-
86
-
-
84871837954
-
Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme
-
Craciun, S. & Balskus, E. P. Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme. Proc. Natl Acad. Sci. USA 109, 21307-21312 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 21307-21312
-
-
Craciun, S.1
Balskus, E.P.2
-
87
-
-
84877331372
-
Intestinal microbiota metabolism of L carnitine, a nutrient in red meat, promotes atherosclerosis
-
Koeth, R. A. et al. Intestinal microbiota metabolism of L carnitine, a nutrient in red meat, promotes atherosclerosis. Nature Med. 19, 576-585 (2013).
-
(2013)
Nature Med.
, vol.19
, pp. 576-585
-
-
Koeth, R.A.1
-
88
-
-
84867074831
-
A metagenome-wide association study of gut microbiota in type 2 diabetes
-
Qin, J. et al. A metagenome-wide association study of gut microbiota in type 2 diabetes. Nature 490, 55-60 (2012).
-
(2012)
Nature
, vol.490
, pp. 55-60
-
-
Qin, J.1
-
89
-
-
84866146940
-
Diversity, stability and resilience of the human gut microbiota
-
Lozupone, C. A., Stombaugh, J. I., Gordon, J. I., Jansson, J. K. & Knight, R. Diversity, stability and resilience of the human gut microbiota. Nature 489, 220-230 (2012).
-
(2012)
Nature
, vol.489
, pp. 220-230
-
-
Lozupone, C.A.1
Stombaugh, J.I.2
Gordon, J.I.3
Jansson, J.K.4
Knight, R.5
-
90
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou, C. M. et al. Molecular portraits of human breast tumours. Nature 406, 747-752 (2000).
-
(2000)
Nature
, vol.406
, pp. 747-752
-
-
Perou, C.M.1
-
91
-
-
84877254190
-
Integrated genomic characterization of endometrial carcinoma
-
Kandoth, C. et al. Integrated genomic characterization of endometrial carcinoma. Nature 497, 67-73 (2013).
-
(2013)
Nature
, vol.497
, pp. 67-73
-
-
Kandoth, C.1
-
92
-
-
68949216248
-
Systems genetics analysis of cancer susceptibility: From mouse models to humans
-
Quigley, D. & Balmain, A. Systems genetics analysis of cancer susceptibility: from mouse models to humans. Nature Rev. Genet. 10, 651-657 (2009).
-
(2009)
Nature Rev. Genet.
, vol.10
, pp. 651-657
-
-
Quigley, D.1
Balmain, A.2
-
93
-
-
84873419293
-
Systematic deciphering of cancer genome networks
-
Fendler, B. & Atwal, G. Systematic deciphering of cancer genome networks. Yale J. Biol. Med. 85, 339-345 (2012).
-
(2012)
Yale J. Biol. Med.
, vol.85
, pp. 339-345
-
-
Fendler, B.1
Atwal, G.2
-
94
-
-
34548364227
-
Identification of pathways for atherosclerosis in mice: Integration of quantitative trait locus analysis and global gene expression data
-
DOI 10.1161/CIRCRESAHA.107.152975, PII 0000301220070803000017
-
Wang, S. S. et al. Identification of pathways for atherosclerosis in mice: integration of quantitative trait locus analysis and global gene expression data. Circ. Res. 101, e11-e30 (2007). (Pubitemid 47344081)
-
(2007)
Circulation Research
, vol.101
, Issue.3
-
-
Wang, S.S.1
Schadt, E.E.2
Wang, H.3
Wang, X.4
Ingram-Drake, L.5
Shi, W.6
Drake, T.A.7
Lusis, A.J.8
-
95
-
-
77955003279
-
Identification and validation of genes affecting aortic lesions in mice
-
Yang, X. et al. Identification and validation of genes affecting aortic lesions in mice. J. Clin. Invest. 120, 2414-2422 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 2414-2422
-
-
Yang, X.1
-
96
-
-
20144377218
-
Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease
-
DOI 10.1038/ng1522
-
Hubner, N. et al. Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease. Nature Genet. 37, 243-253 (2005). (Pubitemid 41716251)
-
(2005)
Nature Genetics
, vol.37
, Issue.3
, pp. 243-253
-
-
Hubner, N.1
Wallace, C.A.2
Zimdahl, H.3
Petretto, E.4
Schulz, H.5
Maciver, F.6
Mueller, M.7
Hummel, O.8
Monti, J.9
Zidek, V.10
Musilova, A.11
Kren, V.12
Causton, H.13
Game, L.14
Born, G.15
Schmidt, S.16
Muller, A.17
Cook, S.A.18
Kurtz, T.W.19
Whittaker, J.20
Pravenec, M.21
Aitman, T.J.22
more..
-
97
-
-
80053897262
-
Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function
-
McDermott-Roe, C. et al. Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function. Nature 478, 114-118 (2011).
-
(2011)
Nature
, vol.478
, pp. 114-118
-
-
McDermott-Roe, C.1
-
98
-
-
84872047522
-
Identification of cross-species shared transcriptional networks of diabetic nephropathy in human and mouse glomeruli
-
Hodgin, J. B. et al. Identification of cross-species shared transcriptional networks of diabetic nephropathy in human and mouse glomeruli. Diabetes 62, 299-308 (2012).
-
(2012)
Diabetes
, vol.62
, pp. 299-308
-
-
Hodgin, J.B.1
-
99
-
-
77955594299
-
Physiological insights gained from gene expression analysis in obesity and diabetes
-
Keller, M. P. & Attie, A. D. Physiological insights gained from gene expression analysis in obesity and diabetes. Annu. Rev. Nutr. 30, 341-364 (2010).
-
(2010)
Annu. Rev. Nutr.
, vol.30
, pp. 341-364
-
-
Keller, M.P.1
Attie, A.D.2
-
100
-
-
33645770040
-
Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity
-
Wang, S. et al. Genetic and genomic analysis of a fat mass trait with complex inheritance reveals marked sex specificity. PLoS Genet. 2, e15 (2006).
-
(2006)
PLoS Genet.
, vol.2
-
-
Wang, S.1
-
101
-
-
63449132586
-
Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks
-
Yang, X. et al. Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks. Nature Genet. 41, 415-423 (2009).
-
(2009)
Nature Genet.
, vol.41
, pp. 415-423
-
-
Yang, X.1
-
102
-
-
84872047118
-
Systems genetic analysis of osteoblast-lineage cells
-
Calabrese, G. et al. Systems genetic analysis of osteoblast-lineage cells. PLoS Genet. 8, e1003150 (2012).
-
(2012)
PLoS Genet.
, vol.8
-
-
Calabrese, G.1
-
103
-
-
79955638043
-
Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis
-
Farber, C. R. et al. Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis. PLoS Genet. 7, e1002038 (2011).
-
(2011)
PLoS Genet.
, vol.7
-
-
Farber, C.R.1
-
104
-
-
79952602299
-
Gene networks associated with conditional fear in mice identified using a systems genetics approach
-
Park, C. C. et al. Gene networks associated with conditional fear in mice identified using a systems genetics approach. BMC Syst. Biol. 5, 43 (2011).
-
(2011)
BMC Syst. Biol.
, vol.5
, pp. 43
-
-
Park, C.C.1
-
105
-
-
84874682007
-
Systems-level approaches reveal conservation of trans-regulated genes in the rat and genetic determinants of blood pressure in humans
-
Langley, S. R. et al. Systems-level approaches reveal conservation of trans-regulated genes in the rat and genetic determinants of blood pressure in humans. Cardiovasc. Res. 97, 653-665 (2013).
-
(2013)
Cardiovasc. Res.
, vol.97
, pp. 653-665
-
-
Langley, S.R.1
-
106
-
-
84877809305
-
Genome-wide association mapping of blood cell traits in mice
-
Davis, R. C. et al. Genome-wide association mapping of blood cell traits in mice. Mamm. Genome 24, 105-118 (2013).
-
(2013)
Mamm. Genome
, vol.24
, pp. 105-118
-
-
Davis, R.C.1
-
107
-
-
84879692177
-
Combined sequence-based and genetic mapping analysis of complex traits in outbred rats
-
Baud, A. et al. Combined sequence-based and genetic mapping analysis of complex traits in outbred rats. Nature Genet. 45, 767-775 (2013).
-
(2013)
Nature Genet.
, vol.45
, pp. 767-775
-
-
Baud, A.1
-
108
-
-
84883530603
-
The systems genetics resource (SGR): A web application to mine global data for complex disease traits
-
van Nas, A. et al. The systems genetics resource (SGR): a web application to mine global data for complex disease traits. Front. Genet. 4, 84 (2013).
-
(2013)
Front. Genet.
, vol.4
, pp. 84
-
-
Van Nas, A.1
-
109
-
-
64049085062
-
A network view of disease and compound screening
-
Schadt, E. E., Friend, S. H. & Shaywitz, D. A. A network view of disease and compound screening. Nature Rev. Drug Discov. 8, 286-295 (2009).
-
(2009)
Nature Rev. Drug Discov.
, vol.8
, pp. 286-295
-
-
Schadt, E.E.1
Friend, S.H.2
Shaywitz, D.A.3
-
110
-
-
84860873858
-
Network medicine strikes a blow against breast cancer
-
Erler, J. T. & Linding, R. Network medicine strikes a blow against breast cancer. Cell 149, 731-733 (2012).
-
(2012)
Cell
, vol.149
, pp. 731-733
-
-
Erler, J.T.1
Linding, R.2
-
111
-
-
84860851412
-
Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks
-
Lee, M. J. et al. Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks. Cell 149, 780-794 (2012).
-
(2012)
Cell
, vol.149
, pp. 780-794
-
-
Lee, M.J.1
-
112
-
-
79960332127
-
The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits
-
Min, J. L. et al. The use of genome-wide eQTL associations in lymphoblastoid cell lines to identify novel genetic pathways involved in complex traits. PLoS ONE 6, e22070 (2011).
-
(2011)
PLoS ONE
, vol.6
-
-
Min, J.L.1
-
113
-
-
84870674799
-
RHOA is a modulator of the cholesterol-lowering effects of statin
-
Medina, M. W. et al. RHOA is a modulator of the cholesterol-lowering effects of statin. PLoS Genet. 8, e1003058 (2012).
-
(2012)
PLoS Genet.
, vol.8
-
-
Medina, M.W.1
-
114
-
-
84885864334
-
A statin-dependent QTL for GATM expression is associated with statin-induced myopathy
-
Mangravite, L. M. et al. A statin-dependent QTL for GATM expression is associated with statin-induced myopathy. Nature 502, 377-380 (2013).
-
(2013)
Nature
, vol.502
, pp. 377-380
-
-
Mangravite, L.M.1
-
115
-
-
78549246207
-
Phenomics: The next challenge
-
Houle, D., Govindaraju, D. R. & Omholt, S. Phenomics: the next challenge. Nature Rev. Genet. 11, 855-866 (2010).
-
(2010)
Nature Rev. Genet.
, vol.11
, pp. 855-866
-
-
Houle, D.1
Govindaraju, D.R.2
Omholt, S.3
-
116
-
-
84878682420
-
The Genotype-Tissue Expression (GTEx) project
-
GTEx Consortium
-
GTEx Consortium. The Genotype-Tissue Expression (GTEx) project. Nature Genet. 45, 580-585 (2013).
-
(2013)
Nature Genet.
, vol.45
, pp. 580-585
-
-
-
117
-
-
84868154284
-
The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels
-
Pai, A. A. et al. The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels. PLoS Genet. 8, e1003000 (2012).
-
(2012)
PLoS Genet.
, vol.8
-
-
Pai, A.A.1
-
118
-
-
84861309996
-
Understanding the sexome: Measuring and reporting sex differences in gene systems
-
Arnold, A. P. & Lusis, A. J. Understanding the sexome: measuring and reporting sex differences in gene systems. Endocrinology 153, 2551-2555 (2012).
-
(2012)
Endocrinology
, vol.153
, pp. 2551-2555
-
-
Arnold, A.P.1
Lusis, A.J.2
-
119
-
-
67649644714
-
Elucidating the role of gonadal hormones in sexually dimorphic gene coexpression networks
-
van Nas, A. et al. Elucidating the role of gonadal hormones in sexually dimorphic gene coexpression networks. Endocrinology 150, 1235-1249 (2009).
-
(2009)
Endocrinology
, vol.150
, pp. 1235-1249
-
-
Van Nas, A.1
-
120
-
-
77954143522
-
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
-
Voight, B. F. et al. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nature Genet. 42, 579-589 (2010).
-
(2010)
Nature Genet.
, vol.42
, pp. 579-589
-
-
Voight, B.F.1
-
121
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
Teslovich, T. M. et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466, 707-713 (2010).
-
(2010)
Nature
, vol.466
, pp. 707-713
-
-
Teslovich, T.M.1
-
122
-
-
79957589058
-
Conducting the metabolic syndrome orchestra
-
Civelek, M. & Lusis, A. J. Conducting the metabolic syndrome orchestra. Nature Genet. 43, 506-508 (2011).
-
(2011)
Nature Genet.
, vol.43
, pp. 506-508
-
-
Civelek, M.1
Lusis, A.J.2
-
123
-
-
70249134919
-
Molecular networks as sensors and drivers of common human diseases
-
Schadt, E. E. Molecular networks as sensors and drivers of common human diseases. Nature 461, 218-223 (2009).
-
(2009)
Nature
, vol.461
, pp. 218-223
-
-
Schadt, E.E.1
-
124
-
-
84859959092
-
Stitching together multiple data dimensions reveals interacting metabolomic and transcriptomic networks that modulate cell regulation
-
Zhu, J. et al. Stitching together multiple data dimensions reveals interacting metabolomic and transcriptomic networks that modulate cell regulation. PLoS Biol. 10, e1001301 (2012).
-
(2012)
PLoS Biol.
, vol.10
-
-
Zhu, J.1
-
125
-
-
77953233453
-
Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines
-
Atwell, S. et al. Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines. Nature 465, 627-631 (2010).
-
(2010)
Nature
, vol.465
, pp. 627-631
-
-
Atwell, S.1
-
126
-
-
84870669888
-
More than the sum of its parts: A complex epistatic network underlies natural variation in thermal preference behavior in Caenorhabditis elegans
-
Gaertner, B. E., Parmenter, M. D., Rockman, M. V., Kruglyak, L. & Phillips, P. C. More than the sum of its parts: a complex epistatic network underlies natural variation in thermal preference behavior in Caenorhabditis elegans. Genetics 192, 1533-1542 (2012).
-
(2012)
Genetics
, vol.192
, pp. 1533-1542
-
-
Gaertner, B.E.1
Parmenter, M.D.2
Rockman, M.V.3
Kruglyak, L.4
Phillips, P.C.5
-
127
-
-
77957942349
-
Selection at linked sites shapes heritable phenotypic variation in C. Elegans
-
Rockman, M. V., Skrovanek, S. S. & Kruglyak, L. Selection at linked sites shapes heritable phenotypic variation in C. elegans. Science 330, 372-376 (2010).
-
(2010)
Science
, vol.330
, pp. 372-376
-
-
Rockman, M.V.1
Skrovanek, S.S.2
Kruglyak, L.3
-
128
-
-
77951961924
-
Systems genetics analysis of body weight and energy metabolism traits in Drosophila melanogaster
-
Jumbo-Lucioni, P. et al. Systems genetics analysis of body weight and energy metabolism traits in Drosophila melanogaster. BMC Genomics 11, 297 (2010).
-
(2010)
BMC Genomics
, vol.11
, pp. 297
-
-
Jumbo-Lucioni, P.1
-
129
-
-
84863868317
-
Genetic dissection of a model complex trait using the Drosophila Synthetic Population Resource
-
King, E. G. et al. Genetic dissection of a model complex trait using the Drosophila Synthetic Population Resource. Genome Res. 22, 1558-1566 (2012).
-
(2012)
Genome Res.
, vol.22
, pp. 1558-1566
-
-
King, E.G.1
-
130
-
-
80051562374
-
Genetic analysis in the Collaborative Cross breeding population
-
Philip, V. M. et al. Genetic analysis in the Collaborative Cross breeding population. Genome Res. 21, 1223-1238 (2011).
-
(2011)
Genome Res.
, vol.21
, pp. 1223-1238
-
-
Philip, V.M.1
-
131
-
-
84867335289
-
The Diversity Outbred mouse population
-
Churchill, G. A., Gatti, D. M., Munger, S. C. & Svenson, K. L. The Diversity Outbred mouse population. Mamm. Genome 23, 713-718 (2012).
-
(2012)
Mamm. Genome
, vol.23
, pp. 713-718
-
-
Churchill, G.A.1
Gatti, D.M.2
Munger, S.C.3
Svenson, K.L.4
-
132
-
-
42649111665
-
Progress and prospects in rat genetics: A community view
-
DOI 10.1038/ng.147, PII NG147
-
Aitman, T. J. et al. Progress and prospects in rat genetics: a community view. Nature Genet. 40, 516-522 (2008). (Pubitemid 351601225)
-
(2008)
Nature Genetics
, vol.40
, Issue.5
, pp. 516-522
-
-
Aitman, T.J.1
Critser, J.K.2
Cuppen, E.3
Dominiczak, A.4
Fernandez-Suarez, X.M.5
Flint, J.6
Gauguier, D.7
Geurts, A.M.8
Gould, M.9
Harris, P.C.10
Holmdahl, R.11
Hubner, N.12
Izsvak, Z.13
Jacob, H.J.14
Kuramoto, T.15
Kwitek, A.E.16
Marrone, A.17
Mashimo, T.18
Moreno, C.19
Mullins, J.20
Mullins, L.21
Olsson, T.22
Pravenec, M.23
Riley, L.24
Saar, K.25
Serikawa, T.26
Shull, J.D.27
Szpirer, C.28
Twigger, S.N.29
Voigt, B.30
Worley, K.31
more..
-
133
-
-
0037840360
-
Invited review: HXB/BXH rat recombinant inbred strain platform: A newly enhanced tool for cardiovascular, behavioral, and developmental genetics and genomics
-
Printz, M. P., Jirout, M., Jaworski, R., Alemayehu, A. & Kren, V. Genetic models in applied physiology. HXB/BXH rat recombinant inbred strain platform: a newly enhanced tool for cardiovascular, behavioral, and developmental genetics and genomics. J. Appl. Physiol. 94, 2510-2522 (2003). (Pubitemid 36605316)
-
(2003)
Journal of Applied Physiology
, vol.94
, Issue.6
, pp. 2510-2522
-
-
Printz, M.P.1
Jirout, M.2
Jaworski, R.3
Alemayehu, A.4
Kren, V.5
-
134
-
-
84860214401
-
Genetic basis of transcriptome differences between the founder strains of the rat HXB/BXH recombinant inbred panel
-
Simonis, M. et al. Genetic basis of transcriptome differences between the founder strains of the rat HXB/BXH recombinant inbred panel. Genome Biol. 13, R31 (2012).
-
(2012)
Genome Biol.
, vol.13
-
-
Simonis, M.1
-
135
-
-
84863205594
-
Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men
-
Stancakova, A. et al. Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men. Diabetes 61, 1895-1902 (2012).
-
(2012)
Diabetes
, vol.61
, pp. 1895-1902
-
-
Stancakova, A.1
|