Genetics: Finding genes that underline complex traits

Science

Volumn 298, Issue 5602, 2002, Pages 2345-2349

  Glazier, Anne M ^a   Nadeau, Joseph H ^b   Aitman, Timothy J ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; GENES;

PHENOTYPIC VARIATION;

GENETIC ENGINEERING;

GENE; GENETICS; PHENOTYPE;

ARTIFICIAL SELECTION; ENVIRONMENTAL FACTOR; GENE IDENTIFICATION; GENE MAPPING; GENE TECHNOLOGY; GENETIC ANALYSIS; GENETIC DISORDER; GENETIC HETEROGENEITY; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; GENETIC TRAIT; HUMAN; NONHUMAN; PENETRANCE; PHENOTYPE; PRIORITY JOURNAL; REVIEW; ALLELE; ANIMAL; CHROMOSOME MAP; DNA SEQUENCE; GENETIC PREDISPOSITION; GENETIC VARIABILITY; GENETICS; MULTIFACTORIAL INHERITANCE; MUTATION; PLANT; QUANTITATIVE TRAIT; QUANTITATIVE TRAIT LOCUS; SACCHAROMYCES CEREVISIAE;

ALLELES; ANIMALS; CHROMOSOME MAPPING; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LINKAGE (GENETICS); MULTIFACTORIAL INHERITANCE; MUTATION; PHENOTYPE; PLANTS; QUANTITATIVE TRAIT LOCI; QUANTITATIVE TRAIT, HERITABLE; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS, DNA; VARIATION (GENETICS);

EID: 0037146578     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1076641     Document Type: Review

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60. Supported by the MRC Clinical Sciences Centre and Wellcome Trust Cardiovascular Functional Genomics initiative (TJ.A.) and the Charles B. Wang Foundation (J.H.N.). We thank T. Mackay, M. Burmeister, and C. Wallace for careful reading and constructive criticism of the manuscript.