Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance

Science

Volumn 346, Issue 6212, 2014, Pages 987-991

  Rasmussen, Angela L ^a   Okumura, Atsushi ^a,c   Ferris, Martin T ^b   Green, Richard ^a   Feldmann, Friederike ^c   Kelly, Sara M ^a   Scott, Dana P ^c   Safronetz, David ^c   Haddock, Elaine ^c   LaCasse, Rachel ^c   Thomas, Matthew J ^a   Sova, Pavel ^a   Carter, Victoria S ^a   Weiss, Jeffrey M ^a   Miller, Darla R ^b   Shaw, Ginger D ^b   Korth, Marcus J ^a   Heise, Mark T ^b   Baric, Ralph S ^b   De Villena, Fernando Pardo Manuel ^b   Feldmann, Heinz ^c   Katze, Michael G ^a,d   more..

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d Washington National Primate Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE KINASE; ANGIOPOIETIN RECEPTOR; TEK PROTEIN, MOUSE;

COAGULATION; DISEASE RESISTANCE; GENETIC VARIATION; INFECTIOUS DISEASE; MORTALITY; PATHOGENICITY; PERMEABILITY; PHENOTYPE; PRIMATE; RODENT; VIRAL DISEASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CLOTTING TIME; BLOOD VESSEL PERMEABILITY; CELL ADHESION; EBOLA HEMORRHAGIC FEVER; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HOST; IMMUNE RESPONSE; LYMPHOCYTE DIFFERENTIATION; MORTALITY; MOUSE; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PHENOTYPE; PROTHROMBIN TIME; RNA VIRUS; SEQUENCE ANALYSIS; THROMBIN TIME; VIRUS PATHOGENESIS; VIRUS TITRATION; ALLELE; ANGIOGENESIS; ANIMAL; BLOOD; BLOOD CLOTTING; C57BL MOUSE; CAPILLARY PERMEABILITY; DISEASE MODEL; GENETIC PREDISPOSITION; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; LIVER; LYMPHOCYTE ACTIVATION; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; VASCULAR ENDOTHELIUM; VASCULARIZATION;

ALLELES; ANIMALS; BLOOD COAGULATION; CAPILLARY PERMEABILITY; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; GENETIC PREDISPOSITION TO DISEASE; HEMORRHAGIC FEVER, EBOLA; HOST-PATHOGEN INTERACTIONS; LIVER; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PHYSIOLOGIC; RECEPTOR, TIE-2;

EID: 84911371938     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1259595     Document Type: Article

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