-
1
-
-
66049159816
-
Genetic architecture of quantitative traits in mice, flies, and humans
-
Flint J, Mackay TF, (2009) Genetic architecture of quantitative traits in mice, flies, and humans. Genome Res 19: 723-733.
-
(2009)
Genome Res
, vol.19
, pp. 723-733
-
-
Flint, J.1
Mackay, T.F.2
-
2
-
-
57649128465
-
Applying mouse complex-trait resources to behavioural genetics
-
Flint J, Mott R, (2008) Applying mouse complex-trait resources to behavioural genetics. Nature 456: 724-727.
-
(2008)
Nature
, vol.456
, pp. 724-727
-
-
Flint, J.1
Mott, R.2
-
3
-
-
15944376562
-
Strategies for mapping and cloning quantitative trait genes in rodents
-
Flint J, Valdar W, Shifman S, Mott R, (2005) Strategies for mapping and cloning quantitative trait genes in rodents. Nat Rev Genet 6: 271-286.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 271-286
-
-
Flint, J.1
Valdar, W.2
Shifman, S.3
Mott, R.4
-
4
-
-
33746540478
-
Genome-wide genetic association of complex traits in heterogeneous stock mice
-
Valdar W, Solberg LC, Gauguier D, Burnett S, Klenerman P, et al.(2006) Genome-wide genetic association of complex traits in heterogeneous stock mice. Nat Genet 38: 879-887.
-
(2006)
Nat Genet
, vol.38
, pp. 879-887
-
-
Valdar, W.1
Solberg, L.C.2
Gauguier, D.3
Burnett, S.4
Klenerman, P.5
-
5
-
-
0036786050
-
Double dissociation of function within the hippocampus: spatial memory and hyponeophagia
-
Bannerman DM, Deacon RM, Offen S, Friswell J, Grubb M, et al.(2002) Double dissociation of function within the hippocampus: spatial memory and hyponeophagia. Behav Neurosci 116: 884-901.
-
(2002)
Behav Neurosci
, vol.116
, pp. 884-901
-
-
Bannerman, D.M.1
Deacon, R.M.2
Offen, S.3
Friswell, J.4
Grubb, M.5
-
6
-
-
0037450127
-
Ventral hippocampal lesions affect anxiety but not spatial learning
-
Bannerman DM, Grubb M, Deacon RM, Yee BK, Feldon J, et al.(2003) Ventral hippocampal lesions affect anxiety but not spatial learning. Behav Brain Res 139: 197-213.
-
(2003)
Behav Brain Res
, vol.139
, pp. 197-213
-
-
Bannerman, D.M.1
Grubb, M.2
Deacon, R.M.3
Yee, B.K.4
Feldon, J.5
-
7
-
-
78651447230
-
Brain tissue oxygen amperometry in behaving rats demonstrates functional dissociation of dorsal and ventral hippocampus during spatial processing and anxiety
-
McHugh SB, Fillenz M, Lowry JP, Rawlins JN, Bannerman DM, (2010) Brain tissue oxygen amperometry in behaving rats demonstrates functional dissociation of dorsal and ventral hippocampus during spatial processing and anxiety. Eur J Neurosci 33: 322-337.
-
(2010)
Eur J Neurosci
, vol.33
, pp. 322-337
-
-
McHugh, S.B.1
Fillenz, M.2
Lowry, J.P.3
Rawlins, J.N.4
Bannerman, D.M.5
-
8
-
-
1242336889
-
Amygdala and ventral hippocampus contribute differentially to mechanisms of fear and anxiety
-
McHugh SB, Deacon RM, Rawlins JN, Bannerman DM, (2004) Amygdala and ventral hippocampus contribute differentially to mechanisms of fear and anxiety. Behav Neurosci 118: 63-78.
-
(2004)
Behav Neurosci
, vol.118
, pp. 63-78
-
-
McHugh, S.B.1
Deacon, R.M.2
Rawlins, J.N.3
Bannerman, D.M.4
-
9
-
-
0036679424
-
Reduced fear expression after lesions of the ventral hippocampus
-
Kjelstrup KG, Tuvnes FA, Steffenach HA, Murison R, Moser EI, et al.(2002) Reduced fear expression after lesions of the ventral hippocampus. Proc Natl Acad Sci U S A 99: 10825-10830.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 10825-10830
-
-
Kjelstrup, K.G.1
Tuvnes, F.A.2
Steffenach, H.A.3
Murison, R.4
Moser, E.I.5
-
10
-
-
0004722260
-
QTL analysis identifies multiple behavioral dimensions in ethological tests of anxiety in laboratory mice
-
Turri MG, Datta SR, DeFries J, Henderson ND, Flint J, (2001) QTL analysis identifies multiple behavioral dimensions in ethological tests of anxiety in laboratory mice. Curr Biol 11: 725-734.
-
(2001)
Curr Biol
, vol.11
, pp. 725-734
-
-
Turri, M.G.1
Datta, S.R.2
DeFries, J.3
Henderson, N.D.4
Flint, J.5
-
11
-
-
33845732301
-
The mouse as a model for human biology: a resource guide for complex trait analysis
-
Peters LL, Robledo RF, Bult CJ, Churchill GA, Paigen BJ, et al.(2007) The mouse as a model for human biology: a resource guide for complex trait analysis. Nat Rev Genet 8: 58-69.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 58-69
-
-
Peters, L.L.1
Robledo, R.F.2
Bult, C.J.3
Churchill, G.A.4
Paigen, B.J.5
-
12
-
-
0037836126
-
Multiple cross mapping (MCM) markedly improves the localization of a QTL for ethanol-induced activation
-
Hitzemann R, Malmanger B, Cooper S, Coulombe S, Reed C, et al.(2002) Multiple cross mapping (MCM) markedly improves the localization of a QTL for ethanol-induced activation. Genes Brain Behav 1: 214-222.
-
(2002)
Genes Brain Behav
, vol.1
, pp. 214-222
-
-
Hitzemann, R.1
Malmanger, B.2
Cooper, S.3
Coulombe, S.4
Reed, C.5
-
13
-
-
31544436869
-
Using progenitor strain information to identify quantitative trait nucleotides in outbred mice
-
Yalcin B, Flint J, Mott R, (2005) Using progenitor strain information to identify quantitative trait nucleotides in outbred mice. Genetics 171: 673-681.
-
(2005)
Genetics
, vol.171
, pp. 673-681
-
-
Yalcin, B.1
Flint, J.2
Mott, R.3
-
14
-
-
34547140875
-
The human disease network
-
Goh KI, Cusick ME, Valle D, Childs B, Vidal M, et al.(2007) The human disease network. Proc Natl Acad Sci U S A 104: 8685-8690.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 8685-8690
-
-
Goh, K.I.1
Cusick, M.E.2
Valle, D.3
Childs, B.4
Vidal, M.5
-
15
-
-
0034069495
-
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium
-
Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, et al.(2000) Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 25: 25-29.
-
(2000)
Nat Genet
, vol.25
, pp. 25-29
-
-
Ashburner, M.1
Ball, C.A.2
Blake, J.A.3
Botstein, D.4
Butler, H.5
-
16
-
-
80052851950
-
Mouse genomic variation and its effect on phenotypes and gene regulation
-
Keane TM, Goodstadt L, Danecek P, White MA, Wong K, et al.(2011) Mouse genomic variation and its effect on phenotypes and gene regulation. Nature 477: 289-294.
-
(2011)
Nature
, vol.477
, pp. 289-294
-
-
Keane, T.M.1
Goodstadt, L.2
Danecek, P.3
White, M.A.4
Wong, K.5
-
17
-
-
3042840998
-
Unexpected complexity in the haplotypes of commonly used inbred strains of laboratory mice
-
Yalcin B, Fullerton J, Miller S, Keays DA, Brady S, et al.(2004) Unexpected complexity in the haplotypes of commonly used inbred strains of laboratory mice. Proc Natl Acad Sci U S A 101: 9734-9739.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 9734-9739
-
-
Yalcin, B.1
Fullerton, J.2
Miller, S.3
Keays, D.A.4
Brady, S.5
-
18
-
-
46249114293
-
Mouse segmental duplication and copy number variation
-
She X, Cheng Z, Zollner S, Church DM, Eichler EE, (2008) Mouse segmental duplication and copy number variation. Nat Genet 40: 909-914.
-
(2008)
Nat Genet
, vol.40
, pp. 909-914
-
-
She, X.1
Cheng, Z.2
Zollner, S.3
Church, D.M.4
Eichler, E.E.5
-
19
-
-
11844276055
-
The actin depolymerizing factor n-cofilin is essential for neural tube morphogenesis and neural crest cell migration
-
Gurniak CB, Perlas E, Witke W, (2005) The actin depolymerizing factor n-cofilin is essential for neural tube morphogenesis and neural crest cell migration. Dev Biol 278: 231-241.
-
(2005)
Dev Biol
, vol.278
, pp. 231-241
-
-
Gurniak, C.B.1
Perlas, E.2
Witke, W.3
-
20
-
-
34548850904
-
N-cofilin is associated with neuronal migration disorders and cell cycle control in the cerebral cortex
-
Bellenchi GC, Gurniak CB, Perlas E, Middei S, Ammassari-Teule M, et al.(2007) N-cofilin is associated with neuronal migration disorders and cell cycle control in the cerebral cortex. Genes Dev 21: 2347-2357.
-
(2007)
Genes Dev
, vol.21
, pp. 2347-2357
-
-
Bellenchi, G.C.1
Gurniak, C.B.2
Perlas, E.3
Middei, S.4
Ammassari-Teule, M.5
-
21
-
-
77953105487
-
Learning, AMPA receptor mobility and synaptic plasticity depend on n-cofilin-mediated actin dynamics
-
Rust MB, Gurniak CB, Renner M, Vara H, Morando L, et al.(2010) Learning, AMPA receptor mobility and synaptic plasticity depend on n-cofilin-mediated actin dynamics. EMBO J 29: 1889-1902.
-
(2010)
EMBO J
, vol.29
, pp. 1889-1902
-
-
Rust, M.B.1
Gurniak, C.B.2
Renner, M.3
Vara, H.4
Morando, L.5
-
22
-
-
78650984262
-
The anaphase promoting complex is required for memory function in mice
-
Kuczera T, Stilling RM, Hsia HE, Bahari-Javan S, Irniger S, et al.(2011) The anaphase promoting complex is required for memory function in mice. Learn Mem 18: 49-57.
-
(2011)
Learn Mem
, vol.18
, pp. 49-57
-
-
Kuczera, T.1
Stilling, R.M.2
Hsia, H.E.3
Bahari-Javan, S.4
Irniger, S.5
-
23
-
-
0033213270
-
Essential role for TrkB receptors in hippocampus-mediated learning
-
Minichiello L, Korte M, Wolfer D, Kuhn R, Unsicker K, et al.(1999) Essential role for TrkB receptors in hippocampus-mediated learning. Neuron 24: 401-414.
-
(1999)
Neuron
, vol.24
, pp. 401-414
-
-
Minichiello, L.1
Korte, M.2
Wolfer, D.3
Kuhn, R.4
Unsicker, K.5
-
26
-
-
0037470154
-
The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review
-
Prut L, Belzung C, (2003) The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review. Eur J Pharmacol 463: 3-33.
-
(2003)
Eur J Pharmacol
, vol.463
, pp. 3-33
-
-
Prut, L.1
Belzung, C.2
-
27
-
-
0027292902
-
An assessment of the elevated X-maze for studying anxiety and anxiety-modulating drugs
-
Handley SL, McBlane JW, (1993) An assessment of the elevated X-maze for studying anxiety and anxiety-modulating drugs. J Pharmacol Toxicol Methods 29: 129-138.
-
(1993)
J Pharmacol Toxicol Methods
, vol.29
, pp. 129-138
-
-
Handley, S.L.1
McBlane, J.W.2
-
28
-
-
0034619331
-
A method for fine mapping quantitative trait loci in outbred animal stocks
-
Mott R, Talbot CJ, Turri MG, Collins AC, Flint J, (2000) A method for fine mapping quantitative trait loci in outbred animal stocks. Proc Natl Acad Sci U S A 97: 12649-12654.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 12649-12654
-
-
Mott, R.1
Talbot, C.J.2
Turri, M.G.3
Collins, A.C.4
Flint, J.5
-
29
-
-
78049422154
-
Commercially available outbred mice for genome-wide association studies
-
doi: 10.1371/journal.pgen.1001085
-
Yalcin B, Nicod J, Bhomra A, Davidson S, Cleak J, et al.(2010) Commercially available outbred mice for genome-wide association studies. PLoS Genet 6: e1001085 doi:10.1371/journal.pgen.1001085.
-
(2010)
PLoS Genet
, vol.6
-
-
Yalcin, B.1
Nicod, J.2
Bhomra, A.3
Davidson, S.4
Cleak, J.5
-
30
-
-
79957658264
-
Genetic analysis of complex traits in the emerging Collaborative Cross
-
Aylor DL, Valdar W, Foulds-Mathes W, Buus RJ, Verdugo RA, et al.(2011) Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res 21: 1213-1222.
-
(2011)
Genome Res
, vol.21
, pp. 1213-1222
-
-
Aylor, D.L.1
Valdar, W.2
Foulds-Mathes, W.3
Buus, R.J.4
Verdugo, R.A.5
-
31
-
-
80051562374
-
Genetic analysis in the Collaborative Cross breeding population
-
Philip VM, Sokoloff G, Ackert-Bicknell CL, Striz M, Branstetter L, et al.(2011) Genetic analysis in the Collaborative Cross breeding population. Genome Res 21: 1223-1238.
-
(2011)
Genome Res
, vol.21
, pp. 1223-1238
-
-
Philip, V.M.1
Sokoloff, G.2
Ackert-Bicknell, C.L.3
Striz, M.4
Branstetter, L.5
-
32
-
-
77954140531
-
Common SNPs explain a large proportion of the heritability for human height
-
Yang J, Benyamin B, McEvoy BP, Gordon S, Henders AK, et al.(2010) Common SNPs explain a large proportion of the heritability for human height. Nat Genet 42: 565-569.
-
(2010)
Nat Genet
, vol.42
, pp. 565-569
-
-
Yang, J.1
Benyamin, B.2
McEvoy, B.P.3
Gordon, S.4
Henders, A.K.5
-
33
-
-
66449134529
-
High resolution mapping of expression QTLs in heterogeneous stock mice in multiple tissues
-
Huang GJ, Shifman S, Valdar W, Johannesson M, Yalcin B, et al.(2009) High resolution mapping of expression QTLs in heterogeneous stock mice in multiple tissues. Genome Res 19: 1133-1140.
-
(2009)
Genome Res
, vol.19
, pp. 1133-1140
-
-
Huang, G.J.1
Shifman, S.2
Valdar, W.3
Johannesson, M.4
Yalcin, B.5
-
34
-
-
3042541641
-
Regional dissociations within the hippocampus-memory and anxiety
-
Bannerman DM, Rawlins JN, McHugh SB, Deacon RM, Yee BK, et al.(2004) Regional dissociations within the hippocampus-memory and anxiety. Neurosci Biobehav Rev 28: 273-283.
-
(2004)
Neurosci Biobehav Rev
, vol.28
, pp. 273-283
-
-
Bannerman, D.M.1
Rawlins, J.N.2
McHugh, S.B.3
Deacon, R.M.4
Yee, B.K.5
-
35
-
-
0026635574
-
Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning
-
Phillips RG, LeDoux JE, (1992) Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behavioral Neuroscience 106: 274-285.
-
(1992)
Behavioral Neuroscience
, vol.106
, pp. 274-285
-
-
Phillips, R.G.1
LeDoux, J.E.2
-
36
-
-
0036162399
-
Selective cytotoxic lesions of the retrohippocampal region produce a mild deficit in social recognition memory
-
Bannerman DM, Lemaire M, Yee BK, Iversen SD, Oswald CJ, et al.(2002) Selective cytotoxic lesions of the retrohippocampal region produce a mild deficit in social recognition memory. Exp Brain Res 142: 395-401.
-
(2002)
Exp Brain Res
, vol.142
, pp. 395-401
-
-
Bannerman, D.M.1
Lemaire, M.2
Yee, B.K.3
Iversen, S.D.4
Oswald, C.J.5
-
37
-
-
70649109843
-
Hippocampal NMDA receptors and anxiety: at the interface between cognition and emotion
-
Barkus C, McHugh SB, Sprengel R, Seeburg PH, Rawlins JN, et al.(2010) Hippocampal NMDA receptors and anxiety: at the interface between cognition and emotion. Eur J Pharmacol 626: 49-56.
-
(2010)
Eur J Pharmacol
, vol.626
, pp. 49-56
-
-
Barkus, C.1
McHugh, S.B.2
Sprengel, R.3
Seeburg, P.H.4
Rawlins, J.N.5
-
38
-
-
0026781307
-
Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons
-
Watanabe Y, Gould E, McEwen BS, (1992) Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons. Brain Res 588: 341-345.
-
(1992)
Brain Res
, vol.588
, pp. 341-345
-
-
Watanabe, Y.1
Gould, E.2
McEwen, B.S.3
-
39
-
-
0026939448
-
Phenytoin prevents stress- and corticosterone-induced atrophy of CA3 pyramidal neurons
-
Watanabe Y, Gould E, Cameron HA, Daniels DC, McEwen BS, (1992) Phenytoin prevents stress- and corticosterone-induced atrophy of CA3 pyramidal neurons. Hippocampus 2: 431-435.
-
(1992)
Hippocampus
, vol.2
, pp. 431-435
-
-
Watanabe, Y.1
Gould, E.2
Cameron, H.A.3
Daniels, D.C.4
McEwen, B.S.5
-
40
-
-
77951869291
-
Association of anxiety and depression with microtubule-associated protein 2- and synaptopodin-immunolabeled dendrite and spine densities in hippocampal CA3 of older humans
-
Soetanto A, Wilson RS, Talbot K, Un A, Schneider JA, et al.(2010) Association of anxiety and depression with microtubule-associated protein 2- and synaptopodin-immunolabeled dendrite and spine densities in hippocampal CA3 of older humans. Arch Gen Psychiatry 67: 448-457.
-
(2010)
Arch Gen Psychiatry
, vol.67
, pp. 448-457
-
-
Soetanto, A.1
Wilson, R.S.2
Talbot, K.3
Un, A.4
Schneider, J.A.5
-
41
-
-
65349085563
-
Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis
-
Hotulainen P, Llano O, Smirnov S, Tanhuanpaa K, Faix J, et al.(2009) Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis. J Cell Biol 185: 323-339.
-
(2009)
J Cell Biol
, vol.185
, pp. 323-339
-
-
Hotulainen, P.1
Llano, O.2
Smirnov, S.3
Tanhuanpaa, K.4
Faix, J.5
-
42
-
-
0034928790
-
Morphological changes in dendritic spines associated with long-term synaptic plasticity
-
Yuste R, Bonhoeffer T, (2001) Morphological changes in dendritic spines associated with long-term synaptic plasticity. Annu Rev Neurosci 24: 1071-1089.
-
(2001)
Annu Rev Neurosci
, vol.24
, pp. 1071-1089
-
-
Yuste, R.1
Bonhoeffer, T.2
-
44
-
-
16344375400
-
Dendritic spines and long-term plasticity
-
Segal M, (2005) Dendritic spines and long-term plasticity. Nat Rev Neurosci 6: 277-284.
-
(2005)
Nat Rev Neurosci
, vol.6
, pp. 277-284
-
-
Segal, M.1
-
45
-
-
58149390800
-
Kalirin-7 is required for synaptic structure and function
-
Ma XM, Kiraly DD, Gaier ED, Wang Y, Kim EJ, et al.(2008) Kalirin-7 is required for synaptic structure and function. J Neurosci 28: 12368-12382.
-
(2008)
J Neurosci
, vol.28
, pp. 12368-12382
-
-
Ma, X.M.1
Kiraly, D.D.2
Gaier, E.D.3
Wang, Y.4
Kim, E.J.5
-
46
-
-
81055126115
-
Lipocalin-2 controls neuronal excitability and anxiety by regulating dendritic spine formation and maturation
-
Mucha M, Skrzypiec AE, Schiavon E, Attwood BK, Kucerova E, et al.(2011) Lipocalin-2 controls neuronal excitability and anxiety by regulating dendritic spine formation and maturation. Proc Natl Acad Sci U S A 108: 18436-18441.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 18436-18441
-
-
Mucha, M.1
Skrzypiec, A.E.2
Schiavon, E.3
Attwood, B.K.4
Kucerova, E.5
-
47
-
-
45149105926
-
Efficient control of population structure in model organism association mapping
-
Kang HM, Zaitlen NA, Wade CM, Kirby A, Heckerman D, et al.(2008) Efficient control of population structure in model organism association mapping. Genetics 178: 1709-1723.
-
(2008)
Genetics
, vol.178
, pp. 1709-1723
-
-
Kang, H.M.1
Zaitlen, N.A.2
Wade, C.M.3
Kirby, A.4
Heckerman, D.5
|