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Volumn 21, Issue 11, 2013, Pages 1191-1196

Controlling complexity: The clinical relevance of mouse complex genetics

Author keywords

forward genetics; Mouse model; review

Indexed keywords

OREXIN; TOLL LIKE RECEPTOR 4;

EID: 84885896174     PISSN: 10184813     EISSN: 14765438     Source Type: Journal    
DOI: 10.1038/ejhg.2013.79     Document Type: Review
Times cited : (28)

References (74)
  • 1
    • 84874457770 scopus 로고    scopus 로고
    • Genomic responses in mouse models poorly mimic human inflammatory diseases
    • Seok J, Warren HS, Cuenca AG et al: Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci USA 2013; 110: 3507-3512.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 3507-3512
    • Seok, J.1    Warren, H.S.2    Cuenca, A.G.3
  • 2
    • 77956895712 scopus 로고    scopus 로고
    • SYSGENET: A meeting report from a new European network for systems genetics
    • Schughart K: SYSGENET: a meeting report from a new European network for systems genetics. Mamm Genome 2010; 21: 331-336.
    • (2010) Mamm Genome , vol.21 , pp. 331-336
    • Schughart, K.1
  • 3
    • 0019465678 scopus 로고
    • Studies in histocompatibility
    • Snell GD: Studies in histocompatibility. Science 1981; 213: 172-178. (Pubitemid 11060563)
    • (1981) Science , vol.213 , Issue.4504 , pp. 172-178
    • Snell, G.D.1
  • 4
    • 0017143497 scopus 로고
    • Fusion between immunoglobulin-secreting and nonsecreting myeloma cell lines
    • Kohler G, Howe SC, Milstein C: Fusion between immunoglobulin-secreting and nonsecreting myeloma cell lines. Eur J Immunol 1976; 6: 292-295.
    • (1976) Eur J Immunol , vol.6 , pp. 292-295
    • Kohler, G.1    Howe, S.C.2    Milstein, C.3
  • 5
    • 0017135663 scopus 로고
    • Derivation of specific antibodyproducing tissue culture and tumor lines by cell fusion
    • Kohler G, Milstein C: Derivation of specific antibodyproducing tissue culture and tumor lines by cell fusion. Eur J Immunol 1976; 6: 511-519.
    • (1976) Eur J Immunol , vol.6 , pp. 511-519
    • Kohler, G.1    Milstein, C.2
  • 6
    • 25444501564 scopus 로고    scopus 로고
    • A new set of BXD recombinant inbred lines from advanced intercross populations in mice
    • Peirce JL, Lu L, Gu J, Silver LM, Williams RW: A new set of BXD recombinant inbred lines from advanced intercross populations in mice. BMC Genet 2004; 5: 7.
    • (2004) BMC Genet , vol.5 , pp. 7
    • Peirce, J.L.1    Lu, L.2    Gu, J.3    Silver, L.M.4    Williams, R.W.5
  • 7
    • 0032770189 scopus 로고    scopus 로고
    • Genotyping new BXD recombinant inbred mouse strains and comparison of BXD and consensus maps
    • DOI 10.1007/s003359900998
    • Taylor BA, Wnek C, Kotlus BS, Roeme rN, MacTaggart T, Phillips SJ: Genotyping new BXD recombinant inbred mouse strains and comparison of BXD and consensus maps. Mamm Genome 1999; 10: 335-348. (Pubitemid 29390484)
    • (1999) Mammalian Genome , vol.10 , Issue.4 , pp. 335-348
    • Taylor, B.A.1    Wnek, C.2    Kotlus, B.S.3    Roemer, N.4    MacTaggart, T.5    Phillips, S.J.6
  • 8
    • 84863115856 scopus 로고    scopus 로고
    • The genome architecture of the collaborative cross mouse genetic reference population
    • Collaborative Cross Consortium
    • Collaborative Cross Consortium. The genome architecture of the collaborative cross mouse genetic reference population. Genetics 2012; 190: 389-401.
    • (2012) Genetics , vol.190 , pp. 389-401
  • 11
    • 79957658264 scopus 로고    scopus 로고
    • Genetic analysis of complex traits in the emerging Collaborative Cross
    • Aylor DL, Valdar W, Foulds-Mathes W et al: Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res 2011; 21: 1213-1222.
    • (2011) Genome Res , vol.21 , pp. 1213-1222
    • Aylor, D.L.1    Valdar, W.2    Foulds-Mathes, W.3
  • 12
    • 80051556204 scopus 로고    scopus 로고
    • Collaborative Cross mice and their power to map host susceptibility to Aspergillus fumigatus infection
    • Durrant C, Tayem H, Yalcin B et al: Collaborative Cross mice and their power to map host susceptibility to Aspergillus fumigatus infection. Genome Res 2011; 21: 1239-1248.
    • (2011) Genome Res , vol.21 , pp. 1239-1248
    • Durrant, C.1    Tayem, H.2    Yalcin, B.3
  • 13
    • 80051562374 scopus 로고    scopus 로고
    • Genetic analysis in the Collaborative Cross breeding population
    • Philip VM, Sokoloff G, Ackert-Bicknell CL et al: Genetic analysis in the Collaborative Cross breeding population. Genome Res 2011; 21: 1223-1238.
    • (2011) Genome Res , vol.21 , pp. 1223-1238
    • Philip, V.M.1    Sokoloff, G.2    Ackert-Bicknell, C.L.3
  • 14
    • 3242880810 scopus 로고    scopus 로고
    • ENU mutagenesis in the mouse: Application to human genetic disease
    • Nolan PM, Hugill A, Cox RD: ENU mutagenesis in the mouse: application to human genetic disease. Brief Funct Genomic Proteomic 2002; 1: 278-289.
    • (2002) Brief Funct Genomic Proteomic , vol.1 , pp. 278-289
    • Nolan, P.M.1    Hugill, A.2    Cox, R.D.3
  • 16
    • 7744241091 scopus 로고    scopus 로고
    • Genetic mapping and ENU mutagenesis
    • Beier DR, Herron BJ: Genetic mapping and ENU mutagenesis. Genetica 2004; 122: 65-69.
    • (2004) Genetica , vol.122 , pp. 65-69
    • Beier, D.R.1    Herron, B.J.2
  • 20
    • 78149457743 scopus 로고    scopus 로고
    • ENUbased gene-driven mutagenesis in the mouse: A nextgeneration gene-targeting system
    • Gondo Y, Fukumura R, Murata T, Makino S: ENUbased gene-driven mutagenesis in the mouse: a nextgeneration gene-targeting system. Exp Anim 2010; 59: 537-548.
    • (2010) Exp Anim , vol.59 , pp. 537-548
    • Gondo, Y.1    Fukumura, R.2    Murata, T.3    Makino, S.4
  • 23
    • 0022612671 scopus 로고
    • Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin
    • Freudenberg MA, Keppler D, Galanos C: Requirement for lipopolysaccharide-responsive macrophages in galactosamine-induced sensitization to endotoxin. Infect Immun 1986; 51: 891-895. (Pubitemid 16162992)
    • (1986) Infection and Immunity , vol.51 , Issue.3 , pp. 891-895
    • Freudenberg, M.A.1    Keppler, D.2    Galanos, C.3
  • 25
    • 0037180768 scopus 로고    scopus 로고
    • The immunopathogenesis of sepsis
    • DOI 10.1038/nature01326
    • Cohen J: The immunopathogenesis of sepsis. Nature 2002; 420: 885-891. (Pubitemid 36019643)
    • (2002) Nature , vol.420 , Issue.6917 , pp. 885-891
    • Cohen, J.1
  • 27
    • 67649422321 scopus 로고    scopus 로고
    • Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer
    • O'Neill LA, Bryant CE, Doyle SL: Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer. Pharmacol Rev 2009; 61: 177-197.
    • (2009) Pharmacol Rev , vol.61 , pp. 177-197
    • O'Neill, L.A.1    Bryant, C.E.2    Doyle, S.L.3
  • 28
    • 79951557690 scopus 로고    scopus 로고
    • How host defense is encoded in the mammalian genome
    • Beutler B, Goodnow CC: How host defense is encoded in the mammalian genome. Mamm Genome 2011; 22: 1-5.
    • (2011) Mamm Genome , vol.22 , pp. 1-5
    • Beutler, B.1    Goodnow, C.C.2
  • 31
    • 35448937696 scopus 로고    scopus 로고
    • Differential expression of interferon (IFN) regulatory factors and IFN-stimulated genes at early times after West Nile virus infection of mouse embryo fibroblasts
    • DOI 10.1128/JVI.01359-07
    • Scherbik SV, Stockman BM, Brinton MA: Differential expression of interferon (IFN) regulatory factors and IFN-stimulated genes at early times after West Nile virus infection of mouse embryo fibroblasts. J Virol 2007; 81: 12005-12018. (Pubitemid 47623831)
    • (2007) Journal of Virology , vol.81 , Issue.21 , pp. 12005-12018
    • Scherbik, S.V.1    Stockman, B.M.2    Brinton, M.A.3
  • 32
    • 79960945082 scopus 로고    scopus 로고
    • Transgenic expression of full-length 2',5'-oligoadenylate synthetase 1b confers to BALB/c mice resistance against West Nile virus-induced encephalitis
    • Simon-Chazottes D, Frenkiel MP, Montagutelli X, Guenet JL, Despres P, Panthier JJ: Transgenic expression of full-length 2',5'-oligoadenylate synthetase 1b confers to BALB/c mice resistance against West Nile virus-induced encephalitis. Virology 2011; 417: 147-153.
    • (2011) Virology , vol.417 , pp. 147-153
    • Simon-Chazottes, D.1    Frenkiel, M.P.2    Montagutelli, X.3    Guenet, J.L.4    Despres, P.5    Panthier, J.J.6
  • 33
    • 27744547954 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in genes for 2′-5′- oligoadenylate synthetase and RNase L in patients hospitalized with West Nile virus infection
    • DOI 10.1086/497340
    • Yakub I, Lillibridge KM, Moran A et al: Single nucleotide polymorphisms in genes for 2'-5'-oligoadenylate synthetase and RNase L inpatients hospitalized with West Nile virus infection. J Infect Dis 2005; 192: 1741-1748. (Pubitemid 41587824)
    • (2005) Journal of Infectious Diseases , vol.192 , Issue.10 , pp. 1741-1748
    • Yakub, I.1    Lillibridge, K.M.2    Moran, A.3    Gonzalez, O.Y.4    Belmont, J.5    Gibbs, R.A.6    Tweardy, D.J.7
  • 34
    • 61449157813 scopus 로고    scopus 로고
    • Genetic variation in OAS1 is a risk factor for initial infection with West Nile virus in man
    • Lim JK, Lisco A, McDermott DH et al: Genetic variation in OAS1 is a risk factor for initial infection with West Nile virus in man. PLoS Pathog 2009; 5: e1000321.
    • (2009) PLoS Pathog , vol.5
    • Lim, J.K.1    Lisco, A.2    McDermott, D.H.3
  • 35
    • 77956326416 scopus 로고    scopus 로고
    • Liquid chromatography-mass spectrometry-based parallel metabolic profiling of human and mouse model serum reveals putative biomarkers associated with the progression of nonalcoholic fatty liver disease
    • Barr J, Vazquez-Chantada M, Alonso C et al: Liquid chromatography-mass spectrometry-based parallel metabolic profiling of human and mouse model serum reveals putative biomarkers associated with the progression of nonalcoholic fatty liver disease. J Proteome Res 2010; 9: 4501-4512.
    • (2010) J Proteome Res , vol.9 , pp. 4501-4512
    • Barr, J.1    Vazquez-Chantada, M.2    Alonso, C.3
  • 36
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • DOI 10.1038/27376
    • Friedman JM, Halaas JL: Leptin and the regulation of body weight in mammals. Nature 1998; 395: 763-770. (Pubitemid 28485436)
    • (1998) Nature , vol.395 , Issue.6704 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 40
    • 70149124338 scopus 로고    scopus 로고
    • Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics
    • Koutnikova H, Laakso M, Lu L et al: Identification of the UBP1 locus as a critical blood pressure determinant using a combination of mouse and human genetics. PLoS Genet 2009; 5: e1000591.
    • (2009) PLoS Genet , vol.5
    • Koutnikova, H.1    Laakso, M.2    Lu, L.3
  • 41
    • 34548223196 scopus 로고    scopus 로고
    • Genetic and Genomic Insights into the Molecular Basis of Atherosclerosis
    • DOI 10.1016/j.cmet.2007.07.001, PII S1550413107001891
    • Chen Y, Rollins J, Paigen B, Wang X: Genetic and genomic insights into the molecular basis of atherosclerosis. Cell Metab 2007; 6: 164-179. (Pubitemid 47324136)
    • (2007) Cell Metabolism , vol.6 , Issue.3 , pp. 164-179
    • Chen, Y.1    Rollins, J.2    Paigen, B.3    Wang, X.4
  • 42
    • 20144386616 scopus 로고    scopus 로고
    • Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility
    • Wang X, Ria M, Kelmenson PM et al: Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility. Nat Genet 2005; 37: 365-372.
    • (2005) Nat Genet , vol.37 , pp. 365-372
    • Wang, X.1    Ria, M.2    Kelmenson, P.M.3
  • 49
    • 80053102580 scopus 로고    scopus 로고
    • Disrupting the circadian clock: Gene-specific effects on aging, cancer, and other phenotypes
    • Yu EA, Weaver DR: Disrupting the circadian clock: gene-specific effects on aging, cancer, and other phenotypes. Aging (Albany NY) 2011; 3: 479-493.
    • (2011) Aging (Albany NY) , vol.3 , pp. 479-493
    • Yu, E.A.1    Weaver, D.R.2
  • 50
    • 79955749678 scopus 로고    scopus 로고
    • Identifying human disease genes through cross-species gene mapping of evolutionary conserved processes
    • Poot M, Badea A, Williams RW, Kas MJ: Identifying human disease genes through cross-species gene mapping of evolutionary conserved processes. PLoS ONE 2011; 6: e18612.
    • (2011) PLoS ONE , vol.6
    • Poot, M.1    Badea, A.2    Williams, R.W.3    Kas, M.J.4
  • 53
    • 0033826856 scopus 로고    scopus 로고
    • A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains
    • Peyron C, Faraco J, Rogers W et al: A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat Med 2000; 6: 991-997.
    • (2000) Nat Med , vol.6 , pp. 991-997
    • Peyron, C.1    Faraco, J.2    Rogers, W.3
  • 54
    • 84855479864 scopus 로고    scopus 로고
    • Narcolepsy with hypocretin/orexin deficiency, infections and autoimmunity of the brain
    • Kornum BR, Faraco J, Mignot E: Narcolepsy with hypocretin/orexin deficiency, infections and autoimmunity of the brain. Curr Opin Neurobiol 2011; 21: 897-903.
    • (2011) Curr Opin Neurobiol , vol.21 , pp. 897-903
    • Kornum, B.R.1    Faraco, J.2    Mignot, E.3
  • 55
    • 80053231891 scopus 로고    scopus 로고
    • Translational neuroscience of Schizophrenia: Seeking a meeting of minds between mouse and man
    • Kas MJ, Kahn RS, Collier DA et al: Translational neuroscience of Schizophrenia: seeking a meeting of minds between mouse and man. Sci Transl Med 2011; 3: 102mr103.
    • (2011) Sci Transl Med , vol.3
    • Kas, M.J.1    Kahn, R.S.2    Collier, D.A.3
  • 56
    • 70549108065 scopus 로고    scopus 로고
    • Interspecies trait genetics reveals association of Adcy8 with mouse avoidance behavior and a human mood disorder
    • de Mooij-van Malsen AJ, van Lith HA, Oppelaar H et al: Interspecies trait genetics reveals association of Adcy8 with mouse avoidance behavior and a human mood disorder. Biol Psychiatry 2009; 66: 1123-1130.
    • (2009) Biol Psychiatry , vol.66 , pp. 1123-1130
    • De Mooij-Van Malsen, A.J.1    Van Lith, H.A.2    Oppelaar, H.3
  • 59
    • 53149144638 scopus 로고    scopus 로고
    • An association analysis of murine anxiety genes in humans implicates novel candidate genes for anxiety disorders
    • Donner J, Pirkola S, Silander K et al: An association analysis of murine anxiety genes in humans implicates novel candidate genes for anxiety disorders. Biol Psychiatry 2008; 64: 672-680.
    • (2008) Biol Psychiatry , vol.64 , pp. 672-680
    • Donner, J.1    Pirkola, S.2    Silander, K.3
  • 60
    • 79151479579 scopus 로고    scopus 로고
    • Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants
    • Malki K, Uher R, Paya-Cano J et al: Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants. Biol Psychiatry 2011; 69: 360-365.
    • (2011) Biol Psychiatry , vol.69 , pp. 360-365
    • Malki, K.1    Uher, R.2    Paya-Cano, J.3
  • 61
    • 34548348780 scopus 로고    scopus 로고
    • The mouse ascending: Perspectives for human-disease models
    • DOI 10.1038/ncb437, PII NCB437
    • Rosenthal N, Brown S: The mouse ascending: perspectives for human-disease models. Nat Cell Biol 2007; 9: 993-999. (Pubitemid 47338136)
    • (2007) Nature Cell Biology , vol.9 , Issue.9 , pp. 993-999
    • Rosenthal, N.1    Brown, S.2
  • 62
    • 84884443361 scopus 로고    scopus 로고
    • Studying immunology in mice
    • Hedrich H (eds) London, UK: Academic Press
    • Masih-ul A, Mü ller W: Studying immunology in mice; in Hedrich H (eds). The Laboratory Mouse. London, UK: Academic Press, 2012; pp 349-362.
    • (2012) The Laboratory Mouse , pp. 349-362
    • Masih-Ul, A.1    Mü Ller, W.2
  • 63
    • 84860743865 scopus 로고    scopus 로고
    • Towards an encyclopaedia of mammalian gene function: The International Mouse Phenotyping Consortium
    • Brown SD, Moore MW: Towards an encyclopaedia of mammalian gene function: the International Mouse Phenotyping Consortium. Dis Model Mech 2012; 5: 289-292.
    • (2012) Dis Model Mech , vol.5 , pp. 289-292
    • Brown, S.D.1    Moore, M.W.2
  • 64
    • 0020045888 scopus 로고
    • Diabetes-obesity syndromes in mice
    • Coleman DL: Diabetes-obesity syndromes in mice. Diabetes 1982; 31: 1-6. (Pubitemid 12128678)
    • (1982) Diabetes , vol.31 , Issue.SUPPL. 1 , pp. 1-6
    • Coleman, D.L.1
  • 66
    • 77952411362 scopus 로고    scopus 로고
    • Genetic suppression of the circadian Clock mutation by the melatonin biosynthesis pathway
    • Shimomura K, Lowrey PL, Vitaterna MH et al: Genetic suppression of the circadian Clock mutation by the melatonin biosynthesis pathway. Proc Natl Acad Sci USA 2010; 107: 8399-8403.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 8399-8403
    • Shimomura, K.1    Lowrey, P.L.2    Vitaterna, M.H.3
  • 67
    • 84874457770 scopus 로고    scopus 로고
    • Genomic responses in mouse models poorly mimic human inflammatory diseases
    • Seok J, Warren HS, Cuenca AG et al: Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci USA 2013; 110: 3507-3512.
    • (2013) Proc Natl Acad Sci USA , vol.110 , pp. 3507-3512
    • Seok, J.1    Warren, H.S.2    Cuenca, A.G.3
  • 68
    • 0141758327 scopus 로고    scopus 로고
    • Predicting drug efficacy: Knockouts model pipeline drugs of the pharmaceutical industry
    • DOI 10.1016/j.coph.2003.04.002, PII S1471489203001188
    • Zambrowicz BP, Turner CA, Sands AT: Predicting drug efficacy: knockouts model pipeline drugs of the pharmaceutical industry. Curr Opin Pharmacol 2003; 3: 563-570. (Pubitemid 37221139)
    • (2003) Current Opinion in Pharmacology , vol.3 , Issue.5 , pp. 563-570
    • Zambrowicz, B.P.1    Turner, C.A.2    Sands, A.T.3
  • 69
    • 0037267313 scopus 로고    scopus 로고
    • Knockouts model the 100 best-selling drugs - Will they model the next 100?
    • DOI 10.1038/nrd987
    • Zambrowicz BP, Sands AT: Knockouts model the 100 best-selling drugs-will they model the next 100? Nat Rev Drug Discov 2003; 2: 38-51. (Pubitemid 37361623)
    • (2003) Nature Reviews Drug Discovery , vol.2 , Issue.1 , pp. 38-51
    • Zambrowicz, B.P.1    Sands, A.T.2
  • 71
    • 77950679333 scopus 로고    scopus 로고
    • Can animal models of disease reliably inform human studies?
    • van der Worp HB, Howells DW, Sena ES et al: Can animal models of disease reliably inform human studies? PLoS Med 2010; 7: e1000245.
    • (2010) PLoS Med , vol.7
    • Van Der Worp, H.B.1    Howells, D.W.2    Sena, E.S.3
  • 72
    • 84861049288 scopus 로고    scopus 로고
    • Drug discovery: In defence of the animal model
    • Baldarelli RM: Drug discovery: in defence of the animal model. Nature 2012; 485: 309.
    • (2012) Nature , vol.485 , pp. 309
    • Baldarelli, R.M.1
  • 74
    • 84885905536 scopus 로고    scopus 로고
    • Delphi-methode
    • Harting JM, Kerstan T (eds) Ein Studium generale in 100 Begriffen. München, Germany: Piper
    • Hans J: Delphi-Methode; in Harting JM, Kerstan T (eds). Wissen to go. Ein Studium generale in 100 Begriffen. München, Germany: Piper, 2008.
    • (2008) Wissen to Go
    • Hans, J.1


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