-
1
-
-
61849170118
-
Full accounting of diabetes and pre-diabetes in the U.S. population in 1988–1994 and 2005–2006
-
Cowie CC, Rust KF, Ford ES, et al. Full accounting of diabetes and pre-diabetes in the U.S. population in 1988–1994 and 2005–2006. Diabetes Care. 2009;32:287–294.
-
(2009)
Diabetes Care
, vol.32
, pp. 287-294
-
-
Cowie, C.C.1
Rust, K.F.2
Ford, E.S.3
-
2
-
-
77951089891
-
-
International Diabetes Federation, 6th ed. Brussels, Belgium: International Diabetes Federation
-
International Diabetes Federation. IDF Diabetes Atlas. 6th ed. Brussels, Belgium: International Diabetes Federation; 2013.
-
(2013)
IDF Diabetes Atlas
-
-
-
3
-
-
0141991939
-
Lifetime risk for diabetes mellitus in the United States
-
Narayan KM, Boyle JP, Thompson TJ, Sorensen SW, Williamson DF. Lifetime risk for diabetes mellitus in the United States. JAMA. 2003;290:1884-1890.
-
(2003)
JAMA
, vol.290
, pp. 1884-1890
-
-
Narayan, K.M.1
Boyle, J.P.2
Thompson, T.J.3
Sorensen, S.W.4
Williamson, D.F.5
-
4
-
-
84899869077
-
Prevalence of type 1 and type 2 diabetes among children and adolescents from 2001 to 2009
-
Dabelea D, Mayer-Davis EJ, Saydah S, et al. Prevalence of type 1 and type 2 diabetes among children and adolescents from 2001 to 2009. JAMA. 2014;311(17):1778-1786.
-
(2014)
JAMA
, vol.311
, Issue.17
, pp. 1778-1786
-
-
Dabelea, D.1
Mayer-Davis, E.J.2
Saydah, S.3
-
6
-
-
84906833736
-
Trends in incidence of type 1 diabetes among non-Hispanic white youth in the U.S., 2002-2009
-
Lawrence JM, Imperatore G, Dabelea D, et al. Trends in incidence of type 1 diabetes among non-Hispanic white youth in the U.S., 2002-2009. Diabetes. 2014;63(11):3938-3945.
-
(2014)
Diabetes
, vol.63
, Issue.11
, pp. 3938-3945
-
-
Lawrence, J.M.1
Imperatore, G.2
Dabelea, D.3
-
7
-
-
77958166339
-
International HBA1c Consensus Committee. 2010 consensus statement on the worldwide standardization of the hemoglobin A1C measurement
-
Hanas R, John G, International HBA1c Consensus Committee. 2010 consensus statement on the worldwide standardization of the hemoglobin A1C measurement. Diabetes Care. 2010;33:1903-1904.
-
(2010)
Diabetes Care
, vol.33
, pp. 1903-1904
-
-
Hanas, R.1
John, G.2
-
8
-
-
9444292411
-
Blood glucose and risk of cardiovascular disease in the Asia Pacific region
-
Lawes CM, Parag V, Bennett DA, et al. Blood glucose and risk of cardiovascular disease in the Asia Pacific region. Diabetes Care. 2004;27:2836-2842.
-
(2004)
Diabetes Care
, vol.27
, pp. 2836-2842
-
-
Lawes, C.M.1
Parag, V.2
Bennett, D.A.3
-
9
-
-
0027375768
-
Quantification of the relationship between insulin sensitivity and β-cell function in human subjects: Evidence for a hyperbolic function
-
Kahn SE, Prigeon RL, McCulloch DK, et al. Quantification of the relationship between insulin sensitivity and β-cell function in human subjects: evidence for a hyperbolic function. Diabetes. 1993; 42(11):1663-1672.
-
(1993)
Diabetes
, vol.42
, Issue.11
, pp. 1663-1672
-
-
Kahn, S.E.1
Prigeon, R.L.2
McCulloch, D.K.3
-
10
-
-
77950356610
-
DPT-1 Study Group. Progression to diabetes in relatives of type 1 diabetic patients: Mechanisms and mode of onset
-
Ferrannini E, Mari A, Nofrate V, Sosenko JM, Skyler JS, DPT-1 Study Group. Progression to diabetes in relatives of type 1 diabetic patients: mechanisms and mode of onset. Diabetes 2010;59:679-685.
-
(2010)
Diabetes
, vol.59
, pp. 679-685
-
-
Ferrannini, E.1
Mari, A.2
Nofrate, V.3
Sosenko, J.M.4
Skyler, J.S.5
-
11
-
-
80052827105
-
Progressive erosion of β-cell function precedes the onset of hyperglycemia in the NOD mouse model of type 1 diabetes
-
Ize-Ludlow D, Lightfoot YL, Parker M, et al. Progressive erosion of β-cell function precedes the onset of hyperglycemia in the NOD mouse model of type 1 diabetes. Diabetes. 2011;60:2086-2091.
-
(2011)
Diabetes
, vol.60
, pp. 2086-2091
-
-
Ize-Ludlow, D.1
Lightfoot, Y.L.2
Parker, M.3
-
12
-
-
84859553400
-
Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nono-bese diabetic mouse model
-
Tersey SA, Nishiki Y, Templin AT, et al. Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nono-bese diabetic mouse model. Diabetes. 2012;61:818-827.
-
(2012)
Diabetes
, vol.61
, pp. 818-827
-
-
Tersey, S.A.1
Nishiki, Y.2
Templin, A.T.3
-
14
-
-
84883529653
-
Lost in translation: Endoplasmic reticulum stress and the decline of β-cell health in diabetes mellitus
-
Evans-Molina C, Hatanaka M, Mirmira RG. Lost in translation: endoplasmic reticulum stress and the decline of β-cell health in diabetes mellitus. Diabetes Obes Metab. 2013;15(suppl 3):159-169.
-
(2013)
Diabetes Obes Metab
, vol.15
, pp. 159-169
-
-
Evans-Molina, C.1
Hatanaka, M.2
Mirmira, R.G.3
-
16
-
-
77249132284
-
Adipose tissue inflammation in obesity and metabolic syndrome
-
Nishimura S, Manabe I, Nagai R. Adipose tissue inflammation in obesity and metabolic syndrome. Discov Med. 2009;8:55-60.
-
(2009)
Discov Med
, vol.8
, pp. 55-60
-
-
Nishimura, S.1
Manabe, I.2
Nagai, R.3
-
17
-
-
68349150756
-
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
-
Nishimura S, Manabe I, Nagasaki M, et al. CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med. 2009;15:914-920.
-
(2009)
Nat Med
, vol.15
, pp. 914-920
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
-
18
-
-
84878800136
-
Adipose tissue macrophages function as antigen-presenting cells and regulate adipose tissue CD4+ T cells in mice
-
Morris DL, Cho KW, Delproposto JL, et al. Adipose tissue macrophages function as antigen-presenting cells and regulate adipose tissue CD4+ T cells in mice. Diabetes. 2013;62(8):2762-2772.
-
(2013)
Diabetes
, vol.62
, Issue.8
, pp. 2762-2772
-
-
Morris, D.L.1
Cho, K.W.2
Delproposto, J.L.3
-
19
-
-
79959216069
-
Adipose tissue macrophages: Phenotypic plasticity and diversity in lean and obese states
-
Morris DL, Singer K, Lumeng CN. Adipose tissue macrophages: phenotypic plasticity and diversity in lean and obese states. Curr Opin Clin Nutr Metab Care. 2011;14:341-346.
-
(2011)
Curr Opin Clin Nutr Metab Care
, vol.14
, pp. 341-346
-
-
Morris, D.L.1
Singer, K.2
Lumeng, C.N.3
-
20
-
-
84911865268
-
Impact of islet autoimmunity on the progressive β-cell functional decline in type 2 diabetes
-
Brooks-Worrell BM, Boyko EJ, Palmer JP. Impact of islet autoimmunity on the progressive β-cell functional decline in type 2 diabetes. Diabetes Care. 2014;37(12):3286-3293.
-
(2014)
Diabetes Care
, vol.37
, Issue.12
, pp. 3286-3293
-
-
Brooks-Worrell, B.M.1
Boyko, E.J.2
Palmer, J.P.3
-
21
-
-
84891862471
-
Islet-specific T-cell responses and proinflammatory monocytes define subtypes of au-toantibody-negative ketosis-prone diabetes
-
Brooks-Worrell BM, Iyer D, Coraza I, et al. Islet-specific T-cell responses and proinflammatory monocytes define subtypes of au-toantibody-negative ketosis-prone diabetes. Diabetes Care. 2013; 36(12):4098-4103.
-
(2013)
Diabetes Care
, vol.36
, Issue.12
, pp. 4098-4103
-
-
Brooks-Worrell, B.M.1
Iyer, D.2
Coraza, I.3
-
22
-
-
84859449180
-
Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation
-
Eguchi K, Manabe I, Oishi-Tanaka Y, et al. Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation. Cell Metab. 2012;15:518-533.
-
(2012)
Cell Metab
, vol.15
, pp. 518-533
-
-
Eguchi, K.1
Manabe, I.2
Oishi-Tanaka, Y.3
-
23
-
-
34548431826
-
Increased number of islet-associated macrophages in type 2 diabetes
-
Ehses JA, Perren A, Eppler E, et al. Increased number of islet-associated macrophages in type 2 diabetes. Diabetes. 2007;56: 2356-2370.
-
(2007)
Diabetes
, vol.56
, pp. 2356-2370
-
-
Ehses, J.A.1
Perren, A.2
Eppler, E.3
-
24
-
-
9444242665
-
Five stages of evolving β-cell dysfunction during progression to diabetes
-
Weir GC, Bonner-Weir S. Five stages of evolving β-cell dysfunction during progression to diabetes. Diabetes. 2004;53(suppl 3):S16-S21.
-
(2004)
Diabetes
, vol.53
, pp. S16-S21
-
-
Weir, G.C.1
Bonner-Weir, S.2
-
25
-
-
84891856422
-
Expression of mesenchymal and a-cell phenotypic markers in islet β-cells in recently diagnosed diabetes
-
White MG, Marshall HL, Rigby R, et al. Expression of mesenchymal and a-cell phenotypic markers in islet β-cells in recently diagnosed diabetes. Diabetes Care. 2013;36(11):3818-3820.
-
(2013)
Diabetes Care
, vol.36
, Issue.11
, pp. 3818-3820
-
-
White, M.G.1
Marshall, H.L.2
Rigby, R.3
-
26
-
-
84866389264
-
Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure
-
Talchai C, Xuan S, Lin HV, Sussel L, Accili D. Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure. Cell. 2012;150(6):1223-1234.
-
(2012)
Cell
, vol.150
, Issue.6
, pp. 1223-1234
-
-
Talchai, C.1
Xuan, S.2
Lin, H.V.3
Sussel, L.4
Accili, D.5
-
27
-
-
84881218353
-
Inactivation of specific β cell transcription factors in type 2 diabetes
-
Guo S, Dai C, Guo M, et al. Inactivation of specific β cell transcription factors in type 2 diabetes. J Clin Invest. 2013;123(8):3305-3316.
-
(2013)
J Clin Invest
, vol.123
, Issue.8
, pp. 3305-3316
-
-
Guo, S.1
Dai, C.2
Guo, M.3
-
28
-
-
79959386535
-
How does type 1 diabetes develop?: The notion of homicide or β-cell suicide revisited
-
Atkinson MA, Bluestone JA, Eisenbarth GS, et al. How does type 1 diabetes develop?: the notion of homicide or β-cell suicide revisited. Diabetes. 2011;60:1370-1379.
-
(2011)
Diabetes
, vol.60
, pp. 1370-1379
-
-
Atkinson, M.A.1
Bluestone, J.A.2
Eisenbarth, G.S.3
-
29
-
-
67649364114
-
The role of inflammation in insulitis and β-cell loss in type 1 diabetes
-
Eizirik DL, Colli ML, Ortis F. The role of inflammation in insulitis and β-cell loss in type 1 diabetes. Nat Rev Endocrinol. 2009;5:219-226.
-
(2009)
Nat Rev Endocrinol
, vol.5
, pp. 226
-
-
Eizirik, D.L.1
Colli, M.L.2
Ortis, F.3
-
30
-
-
84913619918
-
From immunobiology to β-cell biology: The changing perspective on type 1 diabetes
-
Maganti A, Evans-Molina C, Mirmira RG. From immunobiology to β-cell biology: the changing perspective on type 1 diabetes. Islets. 2014;6.
-
(2014)
Islets
, pp. 6
-
-
Maganti, A.1
Evans-Molina, C.2
Mirmira, R.G.3
-
31
-
-
84859530797
-
ER stress as a trigger for β-cell dysfunction and autoimmunity in type 1 diabetes
-
O’Sullivan-Murphy B, Urano F. ER stress as a trigger for β-cell dysfunction and autoimmunity in type 1 diabetes. Diabetes. 2012; 61:780-781.
-
(2012)
Diabetes
, vol.61
, pp. 780-781
-
-
O’sullivan-Murphy, B.1
Urano, F.2
-
32
-
-
84879459923
-
The pancreatic β cell and type 1 diabetes: Innocent bystander or active participant? Trends Endocrinol
-
Soleimanpour SA, Stoffers DA. The pancreatic β cell and type 1 diabetes: innocent bystander or active participant? Trends Endocrinol. Metab. 2013;24(7):324-331.
-
(2013)
Metab
, vol.24
, Issue.7
, pp. 324-331
-
-
Soleimanpour, S.A.1
Stoffers, D.A.2
-
33
-
-
0036460571
-
First-phase insulin response in young healthy children at genetic and immunological risk for type I diabetes
-
Keskinen P, Korhonen S, Kupila A, et al. First-phase insulin response in young healthy children at genetic and immunological risk for type I diabetes. Diabetologia. 2002;45:1639-1648.
-
(2002)
Diabetologia
, vol.45
, pp. 1639-1648
-
-
Keskinen, P.1
Korhonen, S.2
Kupila, A.3
-
34
-
-
84890076252
-
Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes
-
Engin F, Yermalovich A, Nguyen T, et al. Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes. Sci Transl Med. 2013;5:211ra156.
-
(2013)
Sci Transl Med
, vol.5
-
-
Engin, F.1
Yermalovich, A.2
Nguyen, T.3
-
35
-
-
84866130866
-
Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes
-
Marhfour I, Lopez XM, Lefkaditis D, et al. Expression of endoplasmic reticulum stress markers in the islets of patients with type 1 diabetes. Diabetologia. 2012;55:2417-2420.
-
(2012)
Diabetologia
, vol.55
, pp. 2417-2420
-
-
Marhfour, I.1
Lopez, X.M.2
Lefkaditis, D.3
-
36
-
-
84922562356
-
RokachJ. Biosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acid
-
Powell WS, RokachJ. Biosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acid. Biochim Biophys Acta. 2015;1851(4):340-355.
-
(2015)
Biochim Biophys Acta
, vol.1851
, Issue.4
, pp. 340-355
-
-
Powell, W.S.1
-
37
-
-
80054052917
-
Lipoxygenase and leukotriene pathways: Biochemistry, biology, and roles in disease
-
Haeggström JZ, Funk CD. Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease. Chem Rev. 2011; 111(10):5866-5898.
-
(2011)
Chem Rev
, vol.111
, Issue.10
, pp. 5866-5898
-
-
Haeggström, J.Z.1
Funk, C.D.2
-
38
-
-
84922553449
-
5-Lipoxygen-ase, a key enzyme for leukotriene biosynthesis in health and disease
-
Rådmark O, Werz O, Steinhilber D, Samuelsson B. 5-Lipoxygen-ase, a key enzyme for leukotriene biosynthesis in health and disease. Biochim Biophys Acta. 2015;1851(4):331-339.
-
(2015)
Biochim Biophys Acta
, vol.1851
, Issue.4
, pp. 331-339
-
-
Rådmark, O.1
Werz, O.2
Steinhilber, D.3
Samuelsson, B.4
-
39
-
-
0037178728
-
Identification of 5-lipoxy-genase as a major gene contributing to atherosclerosis susceptibility in mice
-
Mehrabian M, Allayee H, Wong J, et al. Identification of 5-lipoxy-genase as a major gene contributing to atherosclerosis susceptibility in mice. Circ Res. 2002;91(2):120-126.
-
(2002)
Circ Res
, vol.91
, Issue.2
, pp. 120-126
-
-
Mehrabian, M.1
Allayee, H.2
Wong, J.3
-
40
-
-
4644301666
-
The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm
-
Zhao L, Moos MP, Gräbner R, et al. The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm. Nat Med. 2004;10(9):966-973.
-
(2004)
Nat Med
, vol.10
, Issue.9
, pp. 966-973
-
-
Zhao, L.1
Moos, M.P.2
Gräbner, R.3
-
41
-
-
48449097142
-
5-Li-poxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy
-
Gubitosi-Klug RA, Talahalli R, Du Y, Nadler JL, Kern TS. 5-Li-poxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy. Diabetes. 2008;57(5):1387-1393.
-
(2008)
Diabetes
, vol.57
, Issue.5
, pp. 1387-1393
-
-
Gubitosi-Klug, R.A.1
Talahalli, R.2
Du, Y.3
Nadler, J.L.4
Kern, T.S.5
-
42
-
-
0023926997
-
Laychock SG. Biosynthesis of peptidyl leukotrienes and other lipoxygenase products by rat pancreatic islets. Comparison with macrophages and neutrophils
-
Morgan RO, Laychock SG. Biosynthesis of peptidyl leukotrienes and other lipoxygenase products by rat pancreatic islets. Comparison with macrophages and neutrophils. Prostaglandins. 1988; 35(4):609-623.
-
(1988)
Prostaglandins
, vol.35
, Issue.4
, pp. 609-623
-
-
Morgan, R.O.1
-
43
-
-
33847034426
-
The role of arachidonic acid and its metabolites in insulin secretion from human islets of lang-erhans
-
Persaud SJ, Muller D, Belin VD, et al. The role of arachidonic acid and its metabolites in insulin secretion from human islets of lang-erhans. Diabetes. 2007;56:197-203.
-
(2007)
Diabetes
, vol.56
, pp. 197-203
-
-
Persaud, S.J.1
Muller, D.2
Belin, V.D.3
-
44
-
-
43049088783
-
Identification of ALOX5 as a gene regulating adiposity and pancreatic function
-
Mehrabian M, Schulthess FT, Nebohacova M, et al. Identification of ALOX5 as a gene regulating adiposity and pancreatic function. Diabetologia. 2008;51(6):978-988.
-
(2008)
Diabetologia
, vol.51
, Issue.6
, pp. 978-988
-
-
Mehrabian, M.1
Schulthess, F.T.2
Nebohacova, M.3
-
45
-
-
0027196413
-
Purification and characterization of recombinant histidine-tagged human platelet 12-lipoxygenase ex-pressed in a baculovirus/insect cell system
-
Chen XS, Brash AR, Funk CD. Purification and characterization of recombinant histidine-tagged human platelet 12-lipoxygenase ex-pressed in a baculovirus/insect cell system. Eur J Biochem. 1993; 214(3):845-852.
-
(1993)
Eur J Biochem
, vol.214
, Issue.3
, pp. 845-852
-
-
Chen, X.S.1
Brash, A.R.2
Funk, C.D.3
-
46
-
-
16844383761
-
Activation of 12-lipoxygenase in proinflammatory cytokine-mediated β cell toxicity
-
Chen M, Yang ZD, Smith KM, Carter JD, Nadler JL. Activation of 12-lipoxygenase in proinflammatory cytokine-mediated β cell toxicity. Diabetologia. 2005;48:486-495.
-
(2005)
Diabetologia
, vol.48
, pp. 486-495
-
-
Chen, M.1
Yang, Z.D.2
Smith, K.M.3
Carter, J.D.4
Nadler, J.L.5
-
47
-
-
0035180314
-
12/15-lipoxygenase, oxidative modification of LDL and atherogenesis
-
Funk CD, Cyrus T. 12/15-lipoxygenase, oxidative modification of LDL and atherogenesis. Trends Cardiovasc Med. 2001;11:116-124.
-
(2001)
Trends Cardiovasc Med
, vol.11
, pp. 116-124
-
-
Funk, C.D.1
Cyrus, T.2
-
48
-
-
33744550207
-
Inflammation and immune regulation by 12/15-lipoxygenases
-
Kühn H, O’Donnell VB. Inflammation and immune regulation by 12/15-lipoxygenases. Prog Lipid Res. 2006;45:334-356.
-
(2006)
Prog Lipid Res
, vol.45
, pp. 334-356
-
-
Kühn, H.1
O’Donnell, V.B.2
-
49
-
-
76149125754
-
12-Lipoxygenase products reduce insulin secretion and β-cell viability in human islets
-
Ma K, Nunemaker CS, Wu R, Chakrabarti SK, Taylor-Fishwick DA, Nadler JL. 12-Lipoxygenase products reduce insulin secretion and β-cell viability in human islets. J Clin EndocrinolMetab. 2010; 95:887-893.
-
(2010)
J Clin Endocrinolmetab.
, vol.95
, pp. 887-893
-
-
Ma, K.1
Nunemaker, C.S.2
Wu, R.3
Chakrabarti, S.K.4
Taylor-Fishwick, D.A.5
Nadler, J.L.6
-
50
-
-
4444350561
-
Lipid inflammatory mediators in diabetic vascular disease
-
Natarajan R, Nadler JL. Lipid inflammatory mediators in diabetic vascular disease. Arterioscler Thromb Vasc Biol. 2004;24:1542-1548.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1542-1548
-
-
Natarajan, R.1
Nadler, J.L.2
-
51
-
-
49149089376
-
Enantioselective effect of 12(S)-hydroxyeico-satetraenoic acid on 3T6 fibroblast growth through ERK 1/2 and p38 MAPK pathways and cyclin D1 activation
-
Nieves D, Moreno JJ. Enantioselective effect of 12(S)-hydroxyeico-satetraenoic acid on 3T6 fibroblast growth through ERK 1/2 and p38 MAPK pathways and cyclin D1 activation. Biochem Pharmacol. 2008;76(5):654-661.
-
(2008)
Biochem Pharmacol
, vol.76
, Issue.5
, pp. 654-661
-
-
Nieves, D.1
Moreno, J.J.2
-
52
-
-
0011172276
-
A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein
-
Parthasarathy S, Wieland E, Steinberg D. A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein. Proc Natl Acad Sci USA. 1989;86(3):1046-1050.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, Issue.3
, pp. 1046-1050
-
-
Parthasarathy, S.1
Wieland, E.2
Steinberg, D.3
-
54
-
-
33847025363
-
The role of 12/15-lipoxygenase in the expression of interleukin-6 and tumor necrosis factor-a in macrophages
-
Wen Y, Gu J, Chakrabarti SK, et al. The role of 12/15-lipoxygenase in the expression of interleukin-6 and tumor necrosis factor-a in macrophages. Endocrinology. 2007;148:1313-1322.
-
(2007)
Endocrinology
, vol.148
, pp. 1313-1322
-
-
Wen, Y.1
Gu, J.2
Chakrabarti, S.K.3
-
55
-
-
0036716833
-
Induction of cycloox-ygenase-2 gene in pancreatic β-cells by 12-lipoxygenase pathway product 12-hydroxyeicosatetraenoic acid
-
Han X, Chen S, Sun Y, Nadler JL, Bleich D. Induction of cycloox-ygenase-2 gene in pancreatic β-cells by 12-lipoxygenase pathway product 12-hydroxyeicosatetraenoic acid. Mol Endocrinol. 2002; 16:2145-2154.
-
(2002)
Mol Endocrinol
, vol.16
, pp. 2145-2154
-
-
Han, X.1
Chen, S.2
Sun, Y.3
Nadler, J.L.4
Bleich, D.5
-
56
-
-
0036141930
-
Lipoxin-mediated inhibition of IL-12 production by DCs: A mechanism for regulation of microbial immunity
-
Aliberti J, Hieny S, Reis e Sousa C, Serhan CN, Sher A. Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity. Nat Immunol. 2002;3(1):76-82.
-
(2002)
Nat Immunol
, vol.3
, Issue.1
, pp. 76-82
-
-
Aliberti, J.1
Hieny, S.2
Reis E Sousa, C.3
Serhan, C.N.4
Sher, A.5
-
57
-
-
29644436198
-
Cellular and molecular mechanisms of the selective regulation of IL-12 production by 12/ 15-lipoxygenase
-
Middleton MK, Rubinstein T, Puré E. Cellular and molecular mechanisms of the selective regulation of IL-12 production by 12/ 15-lipoxygenase. J Immunol. 2006;176(1):265-274.
-
(2006)
J Immunol
, vol.176
, Issue.1
, pp. 265-274
-
-
Middleton, M.K.1
Rubinstein, T.2
Puré, E.3
-
58
-
-
0037144594
-
Selective interleukin-12 synthesis defect in 12/15-lipoxygenase-deficient macrophages associated with reduced atherosclerosis in a mouse model of familial hypercholesterolemia
-
Zhao L, Cuff CA, Moss E, et al. Selective interleukin-12 synthesis defect in 12/15-lipoxygenase-deficient macrophages associated with reduced atherosclerosis in a mouse model of familial hypercholesterolemia. J Biol Chem. 2002;277(38):35350-35356.
-
(2002)
J Biol Chem
, vol.277
, Issue.38
, pp. 35350-35356
-
-
Zhao, L.1
Cuff, C.A.2
Moss, E.3
-
59
-
-
0037192853
-
Genetic regulation of metabolic pathways in β-cells disrupted by hyperglycemia
-
Laybutt DR, Sharma A, Sgroi DC, Gaudet J, Bonner-Weir S, Weir GC. Genetic regulation of metabolic pathways in β-cells disrupted by hyperglycemia. J Biol Chem. 2002;277:10912-10921.
-
(2002)
J Biol Chem
, vol.277
, pp. 10912-10921
-
-
Laybutt, D.R.1
Sharma, A.2
Sgroi, D.C.3
Gaudet, J.4
Bonner-Weir, S.5
Weir, G.C.6
-
60
-
-
0036160759
-
Role of 12-lipoxygenase and oxidant stress in hyperglycaemia-in-duced acceleration of atherosclerosis in a diabetic pig model
-
Natarajan R, Gerrity RG, Gu JL, Lanting L, Thomas L, Nadler JL. Role of 12-lipoxygenase and oxidant stress in hyperglycaemia-in-duced acceleration of atherosclerosis in a diabetic pig model. Diabetologia. 2002;45:125-133.
-
(2002)
Diabetologia
, vol.45
, pp. 125-133
-
-
Natarajan, R.1
Gerrity, R.G.2
Gu, J.L.3
Lanting, L.4
Thomas, L.5
Nadler, J.L.6
-
61
-
-
0027233841
-
Elevated glucose and angiotensin II increase 12-lipoxygenase activity and expression in porcine aortic smooth muscle cells
-
Natarajan R, Gu JL, Rossi J, et al. Elevated glucose and angiotensin II increase 12-lipoxygenase activity and expression in porcine aortic smooth muscle cells. Proc Natl Acad Sci USA. 1993;90:4947-4951.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4947-4951
-
-
Natarajan, R.1
Gu, J.L.2
Rossi, J.3
-
62
-
-
0028874383
-
Evolution of β-cell dysfunction in the male Zucker diabetic fatty rat
-
Tokuyama Y, Sturis J, DePaoli AM, et al. Evolution of β-cell dysfunction in the male Zucker diabetic fatty rat. Diabetes. 1995;44: 1447-1457.
-
(1995)
Diabetes
, vol.44
, pp. 1447-1457
-
-
Tokuyama, Y.1
Sturis, J.2
Depaoli, A.M.3
-
63
-
-
84906956125
-
12-Lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets
-
Tersey SA, Maier B, Nishiki Y, Maganti AV, Nadler JL, Mirmira RG. 12-Lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets. Mol Cell Biol. 2014;34(19):3735-3745.
-
(2014)
Mol Cell Biol
, vol.34
, Issue.19
, pp. 3735-3745
-
-
Tersey, S.A.1
Maier, B.2
Nishiki, Y.3
Maganti, A.V.4
Nadler, J.L.5
Mirmira, R.G.6
-
64
-
-
78650788269
-
Evidence for activation of inflammatory lipoxygenase pathways in visceral adipose tissue of obese Zucker rats
-
Chakrabarti SK, Wen Y, Dobrian AD, et al. Evidence for activation of inflammatory lipoxygenase pathways in visceral adipose tissue of obese Zucker rats. Am J Physiol Endocrinol Metab. 2011;300: E175-E187.
-
(2011)
Am J Physiol Endocrinol Metab
, vol.300
, pp. E175-E187
-
-
Chakrabarti, S.K.1
Wen, Y.2
Dobrian, A.D.3
-
65
-
-
69749102190
-
12/15-lipoxygenase products induce inflammation and impair insulin signaling in 3T3-L1 adipocytes
-
Chakrabarti SK, Cole BK, Wen Y, Keller SR, Nadler JL. 12/15-lipoxygenase products induce inflammation and impair insulin signaling in 3T3-L1 adipocytes. Obesity. 2009;17:1657-1663.
-
(2009)
Obesity
, vol.17
, pp. 1657-1663
-
-
Chakrabarti, S.K.1
Cole, B.K.2
Wen, Y.3
Keller, S.R.4
Nadler, J.L.5
-
66
-
-
65349093477
-
Increased susceptibility to exacerbated liver injury in hypercholesterolemic ApoE-deficient mice: Potential involvement of oxysterols
-
Ferré N, Martínez-Clemente M, López-Parra M, et al. Increased susceptibility to exacerbated liver injury in hypercholesterolemic ApoE-deficient mice: potential involvement of oxysterols. Am J Physiol Gastrointest Liver Physiol. 2009;296(3):G553-G562.
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.296
, Issue.3
, pp. G553-G562
-
-
Ferré, N.1
Martínez-Clemente, M.2
López-Parra, M.3
-
67
-
-
78649573682
-
Disruption of the 12/15-lipoxygenase gene (Alox15) protects hyperlipidemic mice from nonalcoholic fatty liver disease
-
Martínez-Clemente M, Ferré N, Titos E, et al. Disruption of the 12/15-lipoxygenase gene (Alox15) protects hyperlipidemic mice from nonalcoholic fatty liver disease. Hepatology. 2010;52:1980-1991.
-
(2010)
Hepatology
, vol.52
, pp. 1980-1991
-
-
Martínez-Clemente, M.1
Ferré, N.2
Titos, E.3
-
68
-
-
84867896304
-
Upregulated expression of brain enzymatic markers of arachidonic and docosahexaenoic acid metabolism in a rat model of the metabolic syndrome
-
Taha AY, Gao F, Ramadan E, Cheon Y, Rapoport SI, Kim H-W. Upregulated expression of brain enzymatic markers of arachidonic and docosahexaenoic acid metabolism in a rat model of the metabolic syndrome. BMC Neurosci. 2012;13:131.
-
(2012)
BMC Neurosci
, vol.13
, pp. 131
-
-
Taha, A.Y.1
Gao, F.2
Ramadan, E.3
Cheon, Y.4
Rapoport, S.I.5
Kim, H.-W.6
-
69
-
-
0035797843
-
Shaish A, et al. 12/15-Lipoxygenase gene disruption attenuates atherogenesis in LDL receptor-deficient mice
-
George J, Afek A, Shaish A, et al. 12/15-Lipoxygenase gene disruption attenuates atherogenesis in LDL receptor-deficient mice. Circulation. 2001;104:1646-1650.
-
(2001)
Circulation
, vol.104
, pp. 1646-1650
-
-
George, J.1
Afek, A.2
-
70
-
-
20844446795
-
Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-defi-cient mice
-
Huo Y, Zhao L, Hyman MC, et al. Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-defi-cient mice. Circulation. 2004;110:2024-2031.
-
(2004)
Circulation
, vol.110
, pp. 2024-2031
-
-
Huo, Y.1
Zhao, L.2
Hyman, M.C.3
-
71
-
-
57049099790
-
Pei H, et al. 12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet
-
Nunemaker CS, Chen M, Pei H, et al. 12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet. Am J Physiol Endocrinol Metab. 2008;295:E1065-E1075.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
, pp. E1065-E1075
-
-
Nunemaker, C.S.1
Chen, M.2
-
72
-
-
70349639659
-
Chapman J, et al. 12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice
-
Sears DD, Miles PD, Chapman J, et al. 12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice. PLoS One. 2009;4: e7250.
-
(2009)
Plos One
, vol.4
-
-
Sears, D.D.1
Miles, P.D.2
-
73
-
-
84907203703
-
Adipose tissue 12/15 lipoxygenase pathway in human obesity and diabetes
-
Lieb DC, Brotman JJ, Hatcher MA, et al. Adipose tissue 12/15 lipoxygenase pathway in human obesity and diabetes. J Clin End-crinol Metab. 2014;99(9):E1713-E1720.
-
(2014)
J Clin End-Crinol Metab
, vol.99
, Issue.9
, pp. E1713-E1720
-
-
Lieb, D.C.1
Brotman, J.J.2
Hatcher, M.A.3
-
74
-
-
84872779944
-
Adipose tissue-specific deletion of 12/15-lipoxygenase protects mice from the consequences of a high-fat diet. Mediat
-
Cole BK, Morris MA, Grzesik WJ, Leone KA, Nadler JL. Adipose tissue-specific deletion of 12/15-lipoxygenase protects mice from the consequences of a high-fat diet. Mediat. Inflamm. 2012;2012: 851798.
-
(2012)
Inflamm
, vol.2012
, pp. 851798
-
-
Cole, B.K.1
Morris, M.A.2
Grzesik, W.J.3
Leone, K.A.4
Nadler, J.L.5
-
75
-
-
0034524387
-
Oxidized LDL induces the expression of ALBP/aP2 mRNA and protein in human THP-1 macrophages
-
Fu Y, Luo N, Lopes-Virella MF. Oxidized LDL induces the expression of ALBP/aP2 mRNA and protein in human THP-1 macrophages. J Lipid Res. 2000;41:2017-2023.
-
(2000)
J Lipid Res
, vol.41
, pp. 2017-2023
-
-
Fu, Y.1
Luo, N.2
Lopes-Virella, M.F.3
-
76
-
-
0034959752
-
Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein
-
Makowski L, Boord JB, Maeda K, et al. Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis. Nat Med. 2001;7:699-705.
-
(2001)
E against Atherosclerosis. Nat Med
, vol.7
, pp. 699-705
-
-
Makowski, L.1
Boord, J.B.2
Maeda, K.3
-
77
-
-
17644361955
-
The NOD mouse: A model of immune dysregulation
-
Anderson MS, Bluestone JA. The NOD mouse: a model of immune dysregulation. Annu Rev Immunol. 2005;23:447-485.
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 447-485
-
-
Anderson, M.S.1
Bluestone, J.A.2
-
78
-
-
0027209814
-
Distribution of pancreatic macrophages preceding and during early insulitis in young NOD mice
-
Reddy S, Liu W, Elliott RB. Distribution of pancreatic macrophages preceding and during early insulitis in young NOD mice. Pancreas. 1993;8:602-608.
-
(1993)
Pancreas
, vol.8
, pp. 602-608
-
-
Reddy, S.1
Liu, W.2
Elliott, R.B.3
-
79
-
-
84874339055
-
Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development
-
Green-Mitchell SM, Tersey SA, Cole BK, et al. Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development. PLoS One. 2013;8:e56763.
-
(2013)
Plos One
, vol.8
-
-
Green-Mitchell, S.M.1
Tersey, S.A.2
Cole, B.K.3
-
80
-
-
0031598596
-
The role of 12-lipoxygenase in pancreatic -cells (review)
-
Bleich D, Chen S, Gu JL, Nadler JL. The role of 12-lipoxygenase in pancreatic -cells (review). Int J Mol Med. 1998;1:265-272.
-
(1998)
Int J Mol Med
, vol.1
, pp. 265-272
-
-
Bleich, D.1
Chen, S.2
Gu, J.L.3
Nadler, J.L.4
-
81
-
-
0028972876
-
Interleukin-1 β regulates the expression of a leukocyte type of 12-lipoxygenase in rat islets and RIN m5F cells
-
Bleich D, Chen S, Gu JL, et al. Interleukin-1 β regulates the expression of a leukocyte type of 12-lipoxygenase in rat islets and RIN m5F cells. Endocrinology. 1995;136:5736-5744.
-
(1995)
Endocrinology
, vol.136
, pp. 5736-5744
-
-
Bleich, D.1
Chen, S.2
Gu, J.L.3
-
82
-
-
0026454365
-
Selective expression of an arachidonate 12-lipoxygenase by pancreatic islet β-cells
-
Shannon VR, Ramanadham S, Turk J, Holtzman MJ. Selective expression of an arachidonate 12-lipoxygenase by pancreatic islet β-cells. Am J Physiol. 1992;263:E828-E836.
-
(1992)
Am J Physiol
, vol.263
, pp. E828-E836
-
-
Shannon, V.R.1
Ramanadham, S.2
Turk, J.3
Holtzman, M.J.4
-
83
-
-
0030042403
-
Interleukin-1 enhances pancreatic islet arachidonic acid 12-lipoxygenase product generation by increasing substrate availability through a nitric oxide-dependent mechanism
-
Ma Z, Ramanadham S, Corbett JA, et al. Interleukin-1 enhances pancreatic islet arachidonic acid 12-lipoxygenase product generation by increasing substrate availability through a nitric oxide-dependent mechanism. J Biol Chem. 1996;271:1029-1042.
-
(1996)
J Biol Chem
, vol.271
, pp. 1029-1042
-
-
Ma, Z.1
Ramanadham, S.2
Corbett, J.A.3
-
84
-
-
0033808074
-
Expression of arachidonate 12-lipoxygenase in rat tissues: A possible role in glucagon secretion
-
Kawajiri H, Zhuang D, Qiao N, et al. Expression of arachidonate 12-lipoxygenase in rat tissues: a possible role in glucagon secretion. J Histochem Cytochem. 2000;48(10):1411-1419.
-
(2000)
J Histochem Cytochem
, vol.48
, Issue.10
, pp. 1411-1419
-
-
Kawajiri, H.1
Zhuang, D.2
Qiao, N.3
-
85
-
-
84924973408
-
Expression pattern of 12-lipoxygenase in human islets with type 1 diabetes and type 2 diabetes
-
Grzesik WJ, Nadler JL, Machida Y, Nadler JL, Imai Y, Morris MA. Expression pattern of 12-lipoxygenase in human islets with type 1 diabetes and type 2 diabetes. J Clin Endocrinol Metab. 2015; 100(3):E387-E395.
-
(2015)
J Clin Endocrinol Metab
, vol.100
, Issue.3
, pp. E387-E395
-
-
Grzesik, W.J.1
Nadler, J.L.2
Machida, Y.3
Nadler, J.L.4
Imai, Y.5
Morris, M.A.6
-
86
-
-
84886545834
-
A Smad signaling network regulates islet cell proliferation
-
El-Gohary Y, Tulachan S, Wiersch J, et al. A Smad signaling network regulates islet cell proliferation. Diabetes. 2014;63(1):224-236.
-
(2014)
Diabetes
, vol.63
, Issue.1
, pp. 224-236
-
-
El-Gohary, Y.1
Tulachan, S.2
Wiersch, J.3
-
87
-
-
0032723345
-
Resistanceto type 1 diabetes induction in 12-lipoxygenase knockout mice
-
Bleich D, Chen S, Zipser B, Sun D, Funk CD, Nadler JL. Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice. J Clin Invest. 1999;103:1431-1436.
-
(1999)
J Clin Invest
, vol.103
, pp. 1431-1436
-
-
Bleich, D.1
Chen, S.2
Zipser, B.3
Sun, D.4
Funk, C.D.5
Nadler, J.L.6
-
88
-
-
0031963919
-
GLUT2 in pancreatic islets: Crucial target molecule in diabetes induced with multiple low doses of streptozo-tocin in mice
-
Wang Z, Gleichmann H. GLUT2 in pancreatic islets: crucial target molecule in diabetes induced with multiple low doses of streptozo-tocin in mice. Diabetes. 1998;47:50-56.
-
(1998)
Diabetes
, vol.47
, pp. 50-56
-
-
Wang, Z.1
Gleichmann, H.2
-
89
-
-
43149125857
-
Dendritic cells in islets of Langerhans constitutively present β cell-derived peptides bound to their class II MHC molecules
-
Calderon B, Suri A, Miller MJ, Unanue ER. Dendritic cells in islets of Langerhans constitutively present β cell-derived peptides bound to their class II MHC molecules. Proc Natl Acad Sci USA. 2008; 105:6121-6126.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 6121-6126
-
-
Calderon, B.1
Suri, A.2
Miller, M.J.3
Unanue, E.R.4
-
90
-
-
0031686176
-
Effector mechanisms in low-dose streptozotocin-induced diabetes
-
Luki ML, Stosi-Grujici S, Shahin A. Effector mechanisms in low-dose streptozotocin-induced diabetes. Dev Immunol. 1998;6:119-128.
-
(1998)
Dev Immunol
, vol.6
, pp. 119-128
-
-
Luki, M.L.1
Stosi-Grujici, S.2
Shahin, A.3
-
91
-
-
77953186469
-
The unique hypusine modification of eIF5A promotes islet β cell inflammation and dysfunction in mice
-
Maier B, Ogihara T, Trace AP, et al. The unique hypusine modification of eIF5A promotes islet β cell inflammation and dysfunction in mice. J Clin Invest. 2010;120:2156-2170.
-
(2010)
J Clin Invest
, vol.120
, pp. 2156-2170
-
-
Maier, B.1
Ogihara, T.2
Trace, A.P.3
-
92
-
-
0029984682
-
Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues
-
Lenzen S, Drinkgern J, Tiedge M. Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues. Free Radic Biol Med. 1996;20:463-466.
-
(1996)
Free Radic Biol Med
, vol.20
, pp. 463-466
-
-
Lenzen, S.1
Drinkgern, J.2
Tiedge, M.3
-
93
-
-
84860488264
-
Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet β cell dysfunction
-
Weaver JR, Holman TR, Imai Y, et al. Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet β cell dysfunction. Mol Cell Endocrinol. 2012;358(1):88-95.
-
(2012)
Mol Cell Endocrinol
, vol.358
, Issue.1
, pp. 88-95
-
-
Weaver, J.R.1
Holman, T.R.2
Imai, Y.3
-
94
-
-
35848957485
-
Endoplasmic reticulum stress and oxidative stress: A vicious cycle or a double-edged sword?
-
Malhotra JD, Kaufman RJ. Endoplasmic reticulum stress and oxidative stress: a vicious cycle or a double-edged sword? Antioxid Redox Signal. 2007;9:2277-2293.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 2277-2293
-
-
Malhotra, J.D.1
Kaufman, R.J.2
-
95
-
-
0029047360
-
12(S)-hydroxyeicosatetraenoic acid and 13(S)-hydroxyoctadecadienoic acid regulation of protein kinase C-a in melanoma cells: Role of receptor-mediated hydrolysis of inositol phospholipids
-
Liu B, Khan WA, Hannun YA, et al. 12(S)-hydroxyeicosatetraenoic acid and 13(S)-hydroxyoctadecadienoic acid regulation of protein kinase C-a in melanoma cells: role of receptor-mediated hydrolysis of inositol phospholipids. Proc Natl Acad Sci USA. 1995;92(20): 9323-9327.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, Issue.20
, pp. 9323-9327
-
-
Liu, B.1
Khan, W.A.2
Hannun, Y.A.3
-
96
-
-
79960679626
-
Identification of the orphan G protein-coupled receptor GPR31 as a receptor for 12-(S)-hydroxy-eicosatetraenoic acid
-
Guo Y, Zhang W, Giroux C, et al. Identification of the orphan G protein-coupled receptor GPR31 as a receptor for 12-(S)-hydroxy-eicosatetraenoic acid. J Biol Chem. 2011;286:33832-33840.
-
(2011)
J Biol Chem
, vol.286
, pp. 33832-33840
-
-
Guo, Y.1
Zhang, W.2
Giroux, C.3
-
97
-
-
0035863307
-
15S-hydroxyeicosatetra-enoic acid activates peroxisome proliferator-activated receptor y and inhibits proliferation in PC3 prostate carcinoma cells
-
Shappell SB, Gupta RA, Manning S, et al. 15S-hydroxyeicosatetra-enoic acid activates peroxisome proliferator-activated receptor y and inhibits proliferation in PC3 prostate carcinoma cells. Cancer Res. 2001;61(2):497-503.
-
(2001)
Cancer Res
, vol.61
, Issue.2
, pp. 497-503
-
-
Shappell, S.B.1
Gupta, R.A.2
Manning, S.3
-
98
-
-
0037200067
-
Identification of a novel human eicosanoid receptor coupled to Gi/o
-
Hosoi T, Koguchi Y, Sugikawa E, et al. Identification of a novel human eicosanoid receptor coupled to Gi/o. J Biol Chem. 2002; 277(35):31459-31465.
-
(2002)
J Biol Chem
, vol.277
, Issue.35
, pp. 31459-31465
-
-
Hosoi, T.1
Koguchi, Y.2
Sugikawa, E.3
-
99
-
-
0027231193
-
Mass spectrometric identification and quantitation of arachido-nate-containing phospholipids in pancreatic islets: Prominence of plasmenylethanolamine molecular species
-
Ramanadham S, Bohrer A, Mueller M, Jett P, Gross RW, Turk J. Mass spectrometric identification and quantitation of arachido-nate-containing phospholipids in pancreatic islets: prominence of plasmenylethanolamine molecular species. Biochemistry. 1993; 32(20):5339-5351.
-
(1993)
Biochemistry
, vol.32
, Issue.20
, pp. 5339-5351
-
-
Ramanadham, S.1
Bohrer, A.2
Mueller, M.3
Jett, P.4
Gross, R.W.5
Turk, J.6
-
100
-
-
0027513147
-
Arachidonic acid as a second messenger in glucose-induced insulin secretion from pancreatic β-cells
-
Jones PM, Persaud SJ. Arachidonic acid as a second messenger in glucose-induced insulin secretion from pancreatic β-cells. J Endocrinol. 1993;137(1):7-14.
-
(1993)
J Endocrinol
, vol.137
, Issue.1
, pp. 7-14
-
-
Jones, P.M.1
Persaud, S.J.2
-
101
-
-
0027400494
-
Amplification of insulin secretion by lipid messengers
-
Turk J, Gross RW, Ramanadham S. Amplification of insulin secretion by lipid messengers. Diabetes. 1993;42(3):367-374.
-
(1993)
Diabetes
, vol.42
, Issue.3
, pp. 367-374
-
-
Turk, J.1
Gross, R.W.2
Ramanadham, S.3
-
102
-
-
84878231693
-
Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion
-
Kimple ME, Keller MP, Rabaglia MR, et al. Prostaglandin E2 receptor, EP3, is induced in diabetic islets and negatively regulates glucose- and hormone-stimulated insulin secretion. Diabetes. 2013;62(6):1904-1912.
-
(2013)
Diabetes
, vol.62
, Issue.6
, pp. 1904-1912
-
-
Kimple, M.E.1
Keller, M.P.2
Rabaglia, M.R.3
-
103
-
-
84866371531
-
Cyclooxygenase-2, not microsomal prostaglandin E syn-thase-1, is the mechanism for interleukin-1β-induced prostaglandin E2 production and inhibition of insulin secretion in pancreatic islets
-
Parazzoli S, Harmon JS, Vallerie SN, Zhang T, Zhou H, Robertson RP. Cyclooxygenase-2, not microsomal prostaglandin E syn-thase-1, is the mechanism for interleukin-1β-induced prostaglandin E2 production and inhibition of insulin secretion in pancreatic islets. J Biol Chem. 2012;287(38):32246-32253.
-
(2012)
J Biol Chem
, vol.287
, Issue.38
, pp. 32246-32253
-
-
Parazzoli, S.1
Harmon, J.S.2
Vallerie, S.N.3
Zhang, T.4
Zhou, H.5
Robertson, R.P.6
-
104
-
-
0033615530
-
Prostaglandin E2 mediates inhibition of insulin secretion by interleukin-1β
-
Tran PO, Gleason CE, Poitout V, Robertson RP. Prostaglandin E2 mediates inhibition of insulin secretion by interleukin-1β. J Biol Chem. 1999;274(44):31245-31248.
-
(1999)
J Biol Chem
, vol.274
, Issue.44
, pp. 31245-31248
-
-
Tran, P.O.1
Gleason, C.E.2
Poitout, V.3
Robertson, R.P.4
-
105
-
-
84895064617
-
Geneticablation and short-duration inhibition of lipoxygenase results in increased macroautophagy
-
Jang I, Park S, Cho JW, Yigitkanli K, van Leyen K, Roth J. Genetic ablation and short-duration inhibition of lipoxygenase results in increased macroautophagy. Exp Cell Res. 2014;321(2):276-287.
-
(2014)
Exp Cell Res
, vol.321
, Issue.2
, pp. 276-287
-
-
Jang, I.1
Park, S.2
Cho, J.W.3
Yigitkanli, K.4
Van Leyen, K.5
Roth, J.6
-
106
-
-
33947369029
-
Zileuton: Clinical implications of 5-lipoxygenase inhibition in severe airway disease
-
Berger W, De Chandt MT, Cairns CB. Zileuton: clinical implications of 5-lipoxygenase inhibition in severe airway disease. Int J Clin Pract. 2007;61(4):663-676.
-
(2007)
Int J Clin Pract
, vol.61
, Issue.4
, pp. 663-676
-
-
Berger, W.1
De Chandt, M.T.2
Cairns, C.B.3
-
107
-
-
33646177187
-
Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases
-
Deschamps JD, Kenyon VA, Holman TR. Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases. Bioorg Med Chem. 2006;14:4295-4301.
-
(2006)
Bioorg Med Chem
, vol.14
, pp. 4295-4301
-
-
Deschamps, J.D.1
Kenyon, V.A.2
Holman, T.R.3
-
108
-
-
0037332097
-
Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases
-
Amagata T, Whitman S, Johnson TA, et al. Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases. J Nat Prod. 2003;66:230-235.
-
(2003)
J Nat Prod
, vol.66
, pp. 230-235
-
-
Amagata, T.1
Whitman, S.2
Johnson, T.A.3
-
109
-
-
8844256551
-
Redox inactivation of human 15-lipoxygenase by marine-derived meroditerpenes and synthetic chromanes: Archetypes for a unique class of selective and recyclable inhibitors
-
Cichewicz RH, Kenyon VA, Whitman S, et al. Redox inactivation of human 15-lipoxygenase by marine-derived meroditerpenes and synthetic chromanes: archetypes for a unique class of selective and recyclable inhibitors. J Am Chem Soc. 2004;126(45):14910-14920.
-
(2004)
J am Chem Soc
, vol.126
, Issue.45
, pp. 14910-14920
-
-
Cichewicz, R.H.1
Kenyon, V.A.2
Whitman, S.3
-
110
-
-
0033672475
-
Inhibitors of 15-lipoxygenase from orange peel
-
Malterud KE, Rydland KM. Inhibitors of 15-lipoxygenase from orange peel. J Agric Food Chem. 2000;48(11):5576-5580.
-
(2000)
J Agric Food Chem
, vol.48
, Issue.11
, pp. 5576-5580
-
-
Malterud, K.E.1
Rydland, K.M.2
-
111
-
-
0030948127
-
Modulation of lipoxygenase activity by bacterial hopanoids
-
Moreau RA, Agnew J, Hicks KB, Powell MJ. Modulation of lipoxygenase activity by bacterial hopanoids. J Nat Prod. 1997; 60(4):397-398.
-
(1997)
J Nat Prod
, vol.60
, Issue.4
, pp. 397-398
-
-
Moreau, R.A.1
Agnew, J.2
Hicks, K.B.3
Powell, M.J.4
-
112
-
-
0031672111
-
Characterization of an acetyl-11-keto-β-boswellic acid and arachido-nate-binding regulatory site of 5-lipoxygenase using photoaffinity labeling
-
Sailer ER, Schweizer S, Boden SE, Ammon HP, Safayhi H. Characterization of an acetyl-11-keto-β-boswellic acid and arachido-nate-binding regulatory site of 5-lipoxygenase using photoaffinity labeling. Eur J Biochem. 1998;256(2):364-368.
-
(1998)
Eur J Biochem
, vol.256
, Issue.2
, pp. 364-368
-
-
Sailer, E.R.1
Schweizer, S.2
Boden, S.E.3
Ammon, H.P.4
Safayhi, H.5
-
113
-
-
3242766824
-
Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase
-
Segraves EN, Shah RR, Segraves NL, et al. Probing the activity differences of simple and complex brominated aryl compounds against 15-soybean, 15-human, and 12-human lipoxygenase. J Med Chem. 2004;47(16):4060-4065.
-
(2004)
J Med Chem
, vol.47
, Issue.16
, pp. 4060-4065
-
-
Segraves, E.N.1
Shah, R.R.2
Segraves, N.L.3
-
114
-
-
35148862752
-
Structure-activity relationship studies of fla-vonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2
-
Vasquez-Martinez Y, Ohri RV, Kenyon V, Holman TR, Sepúlveda-Boza S. Structure-activity relationship studies of fla-vonoids as potent inhibitors of human platelet 12-hLO, reticulocyte 15-hLO-1, and prostate epithelial 15-hLO-2. Bioorg Med Chem. 2007;15(23):7408-7425.
-
(2007)
Bioorg Med Chem
, vol.15
, Issue.23
, pp. 7408-7425
-
-
Vasquez-Martinez, Y.1
Ohri, R.V.2
Kenyon, V.3
Holman, T.R.4
Sepúlveda-Boza, S.5
-
115
-
-
0037030657
-
Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean, 12-human, and 15-human lipoxygenase
-
Whitman S, Gezginci M, Timmermann BN, Holman TR. Structure-activity relationship studies of nordihydroguaiaretic acid inhibitors toward soybean, 12-human, and 15-human lipoxygenase. J Med Chem. 2002;45(12):2659-2661.
-
(2002)
J Med Chem
, vol.45
, Issue.12
, pp. 2659-2661
-
-
Whitman, S.1
Gezginci, M.2
Timmermann, B.N.3
Holman, T.R.4
-
116
-
-
33144489526
-
Novel human lipoxygenase inhibitors discovered using virtual screening with homology models
-
Kenyon V, Chorny I, Carvajal WJ, Holman TR, Jacobson MP. Novel human lipoxygenase inhibitors discovered using virtual screening with homology models. J Med Chem. 2006;49(4): 1356-1363.
-
(2006)
J Med Chem
, vol.49
, Issue.4
, pp. 1356-1363
-
-
Kenyon, V.1
Chorny, I.2
Carvajal, W.J.3
Holman, T.R.4
Jacobson, M.P.5
-
117
-
-
34548819617
-
GautschiJT, Whitman S, etal. Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries
-
Deschamps JD, GautschiJT, Whitman S, etal. Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries. Bioorg Med Chem. 2007;15(22):6900-6908.
-
(2007)
Bioorg Med Chem
, vol.15
, Issue.22
, pp. 6900-6908
-
-
Deschamps, J.D.1
-
118
-
-
79961219253
-
Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase
-
Kenyon V, Rai G, Jadhav A, et al. Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase. J Med Chem. 2011;54(15):5485-5497.
-
(2011)
J Med Chem
, vol.54
, Issue.15
, pp. 5485-5497
-
-
Kenyon, V.1
Rai, G.2
Jadhav, A.3
-
119
-
-
84893052137
-
Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl-)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase
-
Luci DK, Jameson JB 2nd, Yasgar A, et al. Synthesis and structure-activity relationship studies of 4-((2-hydroxy-3-methoxybenzyl-)amino)benzenesulfonamide derivatives as potent and selective inhibitors of 12-lipoxygenase. J Med Chem. 2014;57(2):495-506.
-
(2014)
J Med Chem
, vol.57
, Issue.2
, pp. 495-506
-
-
Luci, D.K.1
Jameson, J.B.2
Yasgar, A.3
-
120
-
-
84925483027
-
Selective inhibition of 12-lipoxygenase protects islets and β cells from inflammatory cytokine-mediated β cell dysfunction
-
Taylor-Fishwick DA, Weaver J, Glenn L, et al. Selective inhibition of 12-lipoxygenase protects islets and β cells from inflammatory cytokine-mediated β cell dysfunction. Diabetologia. 2015;58(3): 549-557.
-
(2015)
Diabetologia
, vol.58
, Issue.3
, pp. 549-557
-
-
Taylor-Fishwick, D.A.1
Weaver, J.2
Glenn, L.3
-
121
-
-
38449098081
-
Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes
-
McDuffie M, Maybee NA, Keller SR, Stevens BK, Germey JC, Morris MA, et al. Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes. Diabetes. 2008;57(1):199-208.
-
(2008)
Diabetes
, vol.57
, Issue.1
, pp. 199-208
-
-
McDuffie, M.1
MaYbee, N.A.2
Keller, S.R.3
Stevens, B.K.4
Germey, J.C.5
Morris, M.A.6
|