12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets

Molecular and Cellular Biology

Volumn 34, Issue 19, 2014, Pages 3735-3745

  Tersey, Sarah A ^a   Maier, Bernhard ^a   Nishiki, Yurika ^a   Maganti, Aarthi V ^a   Nadler, Jerry L ^b   Mirmira, Raghavendra G ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE PEROXIDASE 1; INSULIN; TRANSCRIPTION FACTOR NRF2; ALOX15 PROTEIN, MOUSE; ARACHIDONATE 15 LIPOXYGENASE; CYTOKINE; GLUTATHIONE PEROXIDASE; SUPEROXIDE DISMUTASE;

ADAPTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY FAT DISTRIBUTION; CELL INFILTRATION; CONTROLLED STUDY; DYSGLYCEMIA; ENZYME INHIBITION; FEMALE; GENE DELETION; GLUCOSE INTOLERANCE; INSULIN RELEASE; KNOCKOUT MOUSE; LIPID DIET; MACROPHAGE; MALE; MOUSE; NONHUMAN; OBESITY; OXIDATIVE STRESS; PANCREAS ISLET CELL; PANCREAS ISLET CELL HYPERPLASIA; SIGNAL TRANSDUCTION; TISSUE LEVEL; WEIGHT GAIN; ANIMAL; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETICS; HYPERPLASIA; METABOLISM; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PATHOLOGY;

ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; CYTOKINES; DIABETES MELLITUS, EXPERIMENTAL; DIET, HIGH-FAT; FEMALE; GENE EXPRESSION REGULATION; GLUCOSE INTOLERANCE; GLUTATHIONE PEROXIDASE; HYPERPLASIA; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MALE; MICE; MICE, KNOCKOUT; NF-E2-RELATED FACTOR 2; OBESITY; OXIDATIVE STRESS; SUPEROXIDE DISMUTASE;

EID: 84906956125     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00157-14     Document Type: Article

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