Identification of ALOX5 as a gene regulating adiposity and pancreatic function

Diabetologia

Volumn 51, Issue 6, 2008, Pages 978-988

  Mehrabian, M ^a   Schulthess, F T ^a   Nebohacova, M ^a   Castellani, L W ^a   Zhou, Z ^a   Hartiala, J ^c   Oberholzer, J ^d   Lusis, A J ^a   Maedler, K ^a,b   Allayee, H ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF BREMEN   (Germany)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

5 Lipoxygenase; Beta cell function; Inflammation; Insulin secretion; Leukotrienes; Obesity; Type 2 diabetes

Indexed keywords

ARACHIDONATE 5 LIPOXYGENASE; GLUCOSE; INSULIN; LEPTIN; LIPID; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR PDX 1;

ALOX5 GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GLUCOSE METABOLISM; HISTOLOGY; HUMAN; HUMAN CELL; HYPERPLASIA; HYPERTROPHY; IN VITRO STUDY; IN VIVO STUDY; INSULIN METABOLISM; INSULIN RELEASE; INSULIN RESISTANCE; LIPID BLOOD LEVEL; MOUSE; NONHUMAN; OBESITY; PANCREAS FUNCTION; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; WILD TYPE;

ADIPOSE TISSUE; ANIMALS; ARACHIDONATE 5-LIPOXYGENASE; BLOOD GLUCOSE; BODY COMPOSITION; BODY WEIGHT; CARRIER PROTEINS; CROSSES, GENETIC; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; ISLETS OF LANGERHANS; LEPTIN; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PANCREAS; RNA; RNA INTERFERENCE; RNA, SMALL INTERFERING; SEX CHARACTERISTICS; TISSUE DONORS;

EID: 43049088783     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-008-1002-3     Document Type: Article

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