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Volumn 104, Issue 14, 2001, Pages 1646-1650

12/15-Lipoxygenase gene disruption attenuates atherogenesis in LDL receptor-deficient mice

Author keywords

Atherosclerosis; Cells; Lipoproteins; Lipoxygenase; Oxidation

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; LOW DENSITY LIPOPROTEIN RECEPTOR;

EID: 0035797843     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/hc3901.095772     Document Type: Article
Times cited : (171)

References (34)
  • 2
    • 0031048299 scopus 로고    scopus 로고
    • Oxidative modification of LDL and atherogenesis. The 1995 Lewis A. Conner memorial lecture
    • (1997) Circulation , vol.95 , pp. 1062-1071
    • Steinberg, D.1
  • 3
    • 0032487487 scopus 로고    scopus 로고
    • Oxidants and antioxidants in the pathogenesis of atherosclerosis: Implications for the oxidized low density lipoprotein hypothesis
    • (1998) Atherosclerosis , vol.141 , pp. 1-15
    • Heinecke, J.W.1
  • 5
    • 0034619027 scopus 로고    scopus 로고
    • Secondary prevention with antioxidants of cardiovascular disease in endstage renal disease (SPACE): Randomized placebo controlled trial
    • (2000) Lancet , vol.356 , pp. 1213-1218
    • Boaz, M.1    Smetana, S.2    Weinstein, T.3
  • 6
    • 0030916162 scopus 로고    scopus 로고
    • Randomised trial of alpha-tocopherol and beta-carotene supplements on incidence of major coronary events in men with previous myocardial infraction
    • (1997) Lancet , vol.349 , pp. 1715-1720
    • Rapola, J.M.1    Virtamo, J.2    Ripatti, S.3
  • 7
    • 0345109256 scopus 로고    scopus 로고
    • Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: Results of the GISSI-prevenzione trial
    • Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico
    • (1999) Lancet , vol.354 , pp. 447-455
  • 8
    • 0034688195 scopus 로고    scopus 로고
    • Vitamin E supplementation and cardiovascular events in high-risk patients
    • The Heart Outcomes Prevention Evaluation Study Investigators
    • (2000) N Engl J Med , vol.342 , pp. 154-160
    • Yusuf, S.1    Dagenais, G.2    Pogue, J.3
  • 9
    • 0030580406 scopus 로고    scopus 로고
    • The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice
    • (1996) Biochim Biophys Acta , vol.1304 , pp. 65-84
    • Funk, C.D.1
  • 10
    • 0032483448 scopus 로고    scopus 로고
    • The rabbit 15-lipoxygenase preferentially oxygenates LDL cholesterol esters, and this reaction does not require vitamin E
    • (1998) J Biol Chem , vol.273 , pp. 23225-23232
    • Belkner, J.1    Stender, H.2    Kuhn, H.3
  • 13
    • 0029013214 scopus 로고
    • Transfer of 15-lipoxygenase gene into rabbit iliac arteries results in the appearance of oxidation-specific lipid-protein adducts characteristic of oxidized low density lipoprotein
    • (1995) J Clin Invest , vol.95 , pp. 2692-2698
    • Yla-Herttuala, S.1    Luoma, J.2    Vilta, H.3
  • 20
    • 0029844659 scopus 로고    scopus 로고
    • Disruption of 12/15-lipoxygenase expression in peritoneal macrophages: Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein
    • (1996) J Biol Chem , vol.271 , pp. 24055-24062
    • Sun, D.1    Funk, C.D.2
  • 25
    • 0028198105 scopus 로고
    • ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis: Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum
    • (1994) Arterioscler Thromb , vol.14 , pp. 605-616
    • Palinski, W.1    Ord, V.A.2    Plump, A.S.3
  • 28
    • 0028941445 scopus 로고
    • Enhanced levels of lipoperoxides in low density lipoprotein incubated with murine fibroblast expressing high levels of human 15-lipoxygenase
    • (1995) J Biol Chem , vol.270 , pp. 5191-5197
    • Benz, D.J.1    Mol, M.2    Ezaki, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.