메뉴 건너뛰기




Volumn 45, Issue 12, 2002, Pages 1639-1648

First-phase insulin response in young healthy children at genetic and immunological risk for Type I diabetes

Author keywords

Autoantibodies; HLA risk markers; Insulin secretion; Prediabetic state; Type I diabetes

Indexed keywords

AUTOANTIBODY; INSULIN; INSULIN ANTIBODY; PANCREAS ISLET CELL ANTIBODY; GLUTAMATE DECARBOXYLASE ANTIBODY; HLA DQB1 ANTIGEN; IA ANTIGEN;

EID: 0036460571     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-002-0981-8     Document Type: Article
Times cited : (70)

References (34)
  • 1
    • 0032832621 scopus 로고    scopus 로고
    • Identification of the docked granule pool responsible for the first phase of glucose-stimulated insulin secretion
    • Daniel S, Noda M, Straub SG, Sharp GW “1999” Identification of the docked granule pool responsible for the first phase of glucose-stimulated insulin secretion. Diabetes 48:1686-1690
    • (1999) Diabetes , vol.48 , pp. 1686-1690
    • Daniel, S.1    Noda, M.2    Straub, S.G.3    Sharp, G.W.4
  • 3
    • 0029862542 scopus 로고    scopus 로고
    • Interactions of age, islet cell antibodies, insulin autoantibodies, and first-phase insulin response in predicting risk of progression to IDDM in ICA+ relatives: The ICARUS data set. Islet Cell Antibody Registers Users Study
    • Bingley PJ “1996” Interactions of age, islet cell antibodies, insulin autoantibodies, and first-phase insulin response in predicting risk of progression to IDDM in ICA+ relatives: The ICARUS data set. Islet Cell Antibody Registers Users Study. Diabetes 45:1720-1728
    • (1996) Diabetes , vol.45 , pp. 1720-1728
    • Bingley, P.J.1
  • 4
    • 0021278601 scopus 로고
    • Differential sensitivity to beta-cell secretagogues in "early" type I diabetes mellitus
    • Ganda OP, Srikanta S, Brink SJ et al. “1984” Differential sensitivity to beta-cell secretagogues in "early" type I diabetes mellitus. Diabetes 33:516-521
    • (1984) Diabetes , vol.33 , pp. 516-521
    • Ganda, O.P.1    Srikanta, S.2    Brink, S.J.3
  • 6
    • 0023733856 scopus 로고
    • Low acute insulin response to intravenous glucose. A sensitive but non-specific marker of early stages of Type I “insulin-dependent” diabetes
    • Vialettes B, Mattei-Zevaco C, Badier C, Ramahandridona G, Lassman-Vague V, Vague P “1988” Low acute insulin response to intravenous glucose. A sensitive but non-specific marker of early stages of Type I “insulin-dependent” diabetes. Diabetologia 31:592-596
    • (1988) Diabetologia , vol.31 , pp. 592-596
    • Vialettes, B.1    Mattei-Zevaco, C.2    Badier, C.3    Ramahandridona, G.4    Lassman-Vague, V.5    Vague, P.6
  • 7
    • 0026022192 scopus 로고
    • Predictive value of intravenous glucose tolerance test insulin secretion less than or greater than the first percentile in islet cell antibody positive relatives of Type I “insulin-dependent” diabetic patients
    • Vardi P, Crisa L, Jackson RA “1991” Predictive value of intravenous glucose tolerance test insulin secretion less than or greater than the first percentile in islet cell antibody positive relatives of Type I “insulin-dependent” diabetic patients. Diabetologia 34:93-102
    • (1991) Diabetologia , vol.34 , pp. 93-102
    • Vardi, P.1    Crisa, L.2    Jackson, R.A.3
  • 8
    • 0027213662 scopus 로고
    • Distinction between transient hyperglycemia and early insulin-dependent diabetes mellitus in childhood: A prospective study of incidence and prognostic factors
    • Herskowitz-Dumont R, Wolfsdorf JI, Jackson RA, Eisenbarth GS “1993” Distinction between transient hyperglycemia and early insulin-dependent diabetes mellitus in childhood: A prospective study of incidence and prognostic factors. J Pediatr 123:347-354
    • (1993) J Pediatr , vol.123 , pp. 347-354
    • Herskowitz-Dumont, R.1    Wolfsdorf, J.I.2    Jackson, R.A.3    Eisenbarth, G.S.4
  • 9
    • 0032961804 scopus 로고    scopus 로고
    • Relationship of beta-cell function and autoantibodies to progression and nonprogression of subclinical type 1 diabetes: Follow-up of the Seattle Family Study
    • Greenbaum CJ, Sears KL, Kahn SE, Palmer JP “1999” Relationship of beta-cell function and autoantibodies to progression and nonprogression of subclinical type 1 diabetes: Follow-up of the Seattle Family Study. Diabetes 48:170-175
    • (1999) Diabetes , vol.48 , pp. 170-175
    • Greenbaum, C.J.1    Sears, K.L.2    Kahn, S.E.3    Palmer, J.P.4
  • 10
    • 0024415890 scopus 로고
    • Inter and intra individual variability of acute insulin response during intravenous glucose tolerance tests
    • Bardet S, Pasqual C, Maugendre D, Remy JP, Charbonnel B, Sai P “1989” Inter and intra individual variability of acute insulin response during intravenous glucose tolerance tests. Diabetes Metab 15:224-232
    • (1989) Diabetes Metab , vol.15 , pp. 224-232
    • Bardet, S.1    Pasqual, C.2    Maugendre, D.3    Remy, J.P.4    Charbonnel, B.5    Sai, P.6
  • 12
    • 0025742834 scopus 로고
    • Relationship between first-phase insulin secretion and age. HLA, islet cell antibody status, and development of type 1 diabetes in 220 juvenile first-degree relatives of diabetic patients
    • Robert J-J, Deschamps I, Chevenne D, Roger M, Mogenet A, Boitard C “1991” Relationship between first-phase insulin secretion and age, HLA, islet cell antibody status, and development of type 1 diabetes in 220 juvenile first-degree relatives of diabetic patients. Diabetes Care 14:718-723
    • (1991) Diabetes Care , vol.14 , pp. 718-723
    • Robert, J.-J.1    Deschamps, I.2    Chevenne, D.3    Roger, M.4    Mogenet, A.5    Boitard, C.6
  • 13
    • 0028810686 scopus 로고
    • Human leukocyte antigen identity and DQ risk alleles in autoantibody-positive siblings of children with IDDM are associated with reduced early insulin response
    • Veijola R, Vahasalo P, Tuomilehto-Wolf E et al. “1995” Human leukocyte antigen identity and DQ risk alleles in autoantibody-positive siblings of children with IDDM are associated with reduced early insulin response. Diabetes 44:1021-1028
    • (1995) Diabetes , vol.44 , pp. 1021-1028
    • Veijola, R.1    Vahasalo, P.2    Tuomilehto-Wolf, E.3
  • 14
    • 0035131854 scopus 로고    scopus 로고
    • First-phase insulin release during the intravenous glucose tolerance test as a risk factor for type 1 diabetes
    • Chase HP, Cuthbertson DD, Dolan LM et al. “2001” First-phase insulin release during the intravenous glucose tolerance test as a risk factor for type 1 diabetes. J Pediatr 138:244-249
    • (2001) J Pediatr , vol.138 , pp. 244-249
    • Chase, H.P.1    Cuthbertson, D.D.2    Dolan, L.M.3
  • 16
    • 0035079772 scopus 로고    scopus 로고
    • Feasibility of genetic and immunological prediction of Type I diabetes in a population-based birth cohort
    • Kupila A, Muona P, Simell T et al. “2001” Feasibility of genetic and immunological prediction of Type I diabetes in a population-based birth cohort. Diabetologia 44:290-297
    • (2001) Diabetologia , vol.44 , pp. 290-297
    • Kupila, A.1    Muona, P.2    Simell, T.3
  • 17
    • 0033401173 scopus 로고    scopus 로고
    • Population-based genetic screening for the estimation of type 1 diabetes mellitus risk in Finland: Selective genotyping of markers in the HLA-DQB1, HLA-DQA1 and HLA-DRB1 loci
    • Nejentsev S, Sjoroos M, Soukka T et al. “1999” Population-based genetic screening for the estimation of type 1 diabetes mellitus risk in Finland: Selective genotyping of markers in the HLA-DQB1, HLA-DQA1 and HLA-DRB1 loci. Diabet Med 16:985-992
    • (1999) Diabet Med , vol.16 , pp. 985-992
    • Nejentsev, S.1    Sjoroos, M.2    Soukka, T.3
  • 18
    • 0029042730 scopus 로고
    • Triple-label hybridization assay for type-1 diabetes-related HLA alleles
    • Sjoroos M, Iitia A, Ilonen J, Reijonen H, Lovgren T “1995” Triple-label hybridization assay for type-1 diabetes-related HLA alleles. Biotechniques 18:870-877
    • (1995) Biotechniques , vol.18 , pp. 870-877
    • Sjoroos, M.1    Iitia, A.2    Ilonen, J.3    Reijonen, H.4    Lovgren, T.5
  • 19
    • 0031682106 scopus 로고    scopus 로고
    • Islet cell anti-bodies are less predictive of IDDM among unaffected children in the general population than in sibs of children with diabetes
    • Knip M, Karjalainen J, Åkerblom HK, and the Childhood Diabetes in Finland Study Group “1998” Islet cell anti-bodies are less predictive of IDDM among unaffected children in the general population than in sibs of children with diabetes. Diabetes Care 21:1670-1673
    • (1998) Diabetes Care , vol.21 , pp. 1670-1673
    • Knip, M.1    Karjalainen, J.2    Åkerblom, H.K.3
  • 20
    • 0016261369 scopus 로고
    • Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies
    • Bottazzo GF, Florin-Christensen A, Doniach D “1974” Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies. Lancet ii:1279-1283
    • (1974) Lancet , vol.2 , pp. 1279-1283
    • Bottazzo, G.F.1    Florin-Christensen, A.2    Doniach, D.3
  • 22
    • 0034963425 scopus 로고    scopus 로고
    • Pregnancy induces nonimmunoglobulin insulin-binding activity in both maternal and cord blood serum
    • Ronkainen M, Hamalainen A-M, Koskela P, Åkerblom HK, Knip M “2001” Pregnancy induces nonimmunoglobulin insulin-binding activity in both maternal and cord blood serum. Clin Exp Immunol 124:190-196
    • (2001) Clin Exp Immunol , vol.124 , pp. 190-196
    • Ronkainen, M.1    Hamalainen, A.-M.2    Koskela, P.3    Åkerblom, H.K.4    Knip, M.5
  • 23
    • 0031738116 scopus 로고    scopus 로고
    • Combined use of autoantibodies “IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell anti-bodies” in type 1 diabetes: Combinatorial islet antibody workshop
    • Verge CF, Stenger D, Bonifacio E et al. “1998” Combined use of autoantibodies “IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell anti-bodies” in type 1 diabetes: Combinatorial islet antibody workshop. Diabetes 47:1857-1866
    • (1998) Diabetes , vol.47 , pp. 1857-1866
    • Verge, C.F.1    Stenger, D.2    Bonifacio, E.3
  • 24
    • 0031739110 scopus 로고    scopus 로고
    • Autoantibodies associated with Type I diabetes mellitus persist after diagnosis in children
    • Savola K, Sabbah E, Kulmala P, Vahasalo P, Ilonen J, Knip M “1998” Autoantibodies associated with Type I diabetes mellitus persist after diagnosis in children. Diabetologia 41:1293-1297
    • (1998) Diabetologia , vol.41 , pp. 1293-1297
    • Savola, K.1    Sabbah, E.2    Kulmala, P.3    Vahasalo, P.4    Ilonen, J.5    Knip, M.6
  • 25
    • 6844252890 scopus 로고    scopus 로고
    • IA-2 anti-bodies - A sensitive marker of IDDM with clinical onset in children and adolescents
    • Savola K, Bonifacio E, Sabbah E et al. “1998” IA-2 anti-bodies - A sensitive marker of IDDM with clinical onset in children and adolescents. Diabetologia 41:424-429
    • (1998) Diabetologia , vol.41 , pp. 424-429
    • Savola, K.1    Bonifacio, E.2    Sabbah, E.3
  • 26
    • 0025011787 scopus 로고
    • A prospective study of the development of diabetes in relatives of patients with insulin-dependent diabetes
    • Riley WJ, Maclaren NK, Krischer J et al. “1990” A prospective study of the development of diabetes in relatives of patients with insulin-dependent diabetes. N Engl J Med 323:1167-1172
    • (1990) N Engl J Med , vol.323 , pp. 1167-1172
    • Riley, W.J.1    Maclaren, N.K.2    Krischer, J.3
  • 27
    • 0027197931 scopus 로고
    • Decreased insulin response to glucose in islet cell antibody-negative siblings of type 1 diabetic children
    • Carel JC, Boitard C, Bougneres PF “1993” Decreased insulin response to glucose in islet cell antibody-negative siblings of type 1 diabetic children. J Clin Invest 92:509-513
    • (1993) J Clin Invest , vol.92 , pp. 509-513
    • Carel, J.C.1    Boitard, C.2    Bougneres, P.F.3
  • 28
    • 0033020127 scopus 로고    scopus 로고
    • Only multiple autoantibodies to islet cells “ICA”, insulin. GAD65, IA-2 and IA-2β predict immune-mediated “type 1” diabetes in relatives
    • Maclaren N, Lan M, Coutant R et al. “1999” Only multiple autoantibodies to islet cells “ICA”, insulin, GAD65, IA-2 and IA-2β predict immune-mediated “type 1” diabetes in relatives. J Autoimmun 12:279-287
    • (1999) J Autoimmun , vol.12 , pp. 279-287
    • Maclaren, N.1    Lan, M.2    Coutant, R.3
  • 29
    • 0034047565 scopus 로고    scopus 로고
    • Stability of autoantibodies and their relation to genetic and metabolic markers of Type 1 diabetes in initially unaffected schoolchildren
    • Kulmala P, Rahko J, Savola K et al. “2000” Stability of autoantibodies and their relation to genetic and metabolic markers of Type 1 diabetes in initially unaffected schoolchildren. Diabetologia 43:457-464
    • (2000) Diabetologia , vol.43 , pp. 457-464
    • Kulmala, P.1    Rahko, J.2    Savola, K.3
  • 31
    • 15844419534 scopus 로고    scopus 로고
    • Normal values of first-phase insulin response to intravenous glucose in healthy Italian children and adolescents
    • Lorini R, Vanelli M, and the Prediabetes Study Group of the Italian Society for Pediatric Endocrinology and Diabetology “SIEDP” “1996” Normal values of first-phase insulin response to intravenous glucose in healthy Italian children and adolescents. J Pediatr Endocrinol Metab 9:163-167
    • (1996) J Pediatr Endocrinol Metab , vol.9 , pp. 163-167
    • Lorini, R.1    Vanelli, M.2
  • 32
    • 0028276510 scopus 로고
    • Early environmental events as a cause of IDDM. Evidence and implications
    • Leslie RD, Elliott RB “1994” Early environmental events as a cause of IDDM. Evidence and implications. Diabetes 43:843-850
    • (1994) Diabetes , vol.43 , pp. 843-850
    • Leslie, R.D.1    Elliott, R.B.2
  • 33
    • 0033016840 scopus 로고    scopus 로고
    • Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: The 2-year analysis of the German BABYDIAB Study
    • Ziegler AG, Hummel M, Schenker M, Bonifacio E “1999” Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: The 2-year analysis of the German BABYDIAB Study. Diabetes 48:460-468
    • (1999) Diabetes , vol.48 , pp. 460-468
    • Ziegler, A.G.1    Hummel, M.2    Schenker, M.3    Bonifacio, E.4
  • 34
    • 0036313575 scopus 로고    scopus 로고
    • Genetic risk determines the emergence of diabetes-associated autoanti-bodies in young children
    • Kupila A, Keskinen P, Simell T et al. “2002” Genetic risk determines the emergence of diabetes-associated autoanti-bodies in young children. Diabetes 51:646-651
    • (2002) Diabetes , vol.51 , pp. 646-651
    • Kupila, A.1    Keskinen, P.2    Simell, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.