Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet beta cell dysfunction

Molecular and Cellular Endocrinology

Volumn 358, Issue 1, 2012, Pages 88-95

  Weaver, Jessica R ^a   Holman, Theodore R ^b   Imai, Yumi ^a   Jadhav, Ajit ^c   Kenyon, Victor ^b   Maloney, David J ^c   Nadler, Jerry L ^a   Rai, Ganesha ^c   Simeonov, Anton ^c   Taylor Fishwick, David A ^a  

^a EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

12 Lipoxygenase; Cytokines; Diabetes; Inhibitors; Islet beta cell; NADPH oxidase

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; APOCYNIN; ARACHIDONATE 12 LIPOXYGENASE; CASPASE 3; CYTOKINE; DIPHENYLIODONIUM SALT; GAMMA INTERFERON; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; GENE EXPRESSION; HUMAN; HUMAN CELL; INSULIN RESPONSE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; UPREGULATION;

ACETOPHENONES; ANIMALS; APOPTOSIS; ARACHIDONATE 12-LIPOXYGENASE; CASPASE 3; CHEMOKINE CCL2; DIABETES MELLITUS; EICOSAPENTAENOIC ACID; ENZYME ACTIVATION; HUMANS; INSULIN-SECRETING CELLS; INTERFERON-GAMMA; INTERLEUKIN-1BETA; MICE; NADH, NADPH OXIDOREDUCTASES; ONIUM COMPOUNDS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84860488264     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2012.03.004     Document Type: Article

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