-
1
-
-
77952303410
-
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
-
Allen IC, TeKippe EM, Woodford RM, Uronis JM, Holl EK, Rogers AB, Herfarth HH, Jobin C, Ting JP. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. J Exp Med 207: 1045-1056, 2010.
-
(2010)
J Exp Med
, vol.207
, pp. 1045-1056
-
-
Allen, I.C.1
Tekippe, E.M.2
Woodford, R.M.3
Uronis, J.M.4
Holl, E.K.5
Rogers, A.B.6
Herfarth, H.H.7
Jobin, C.8
Ting, J.P.9
-
2
-
-
84861460062
-
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-kappaB signaling
-
Allen IC, Wilson JE, Schneider M, Lich JD, Roberts RA, Arthur JC, Woodford RM, Davis BK, Uronis JM, Herfarth HH, Jobin C, Rogers AB, Ting JP. NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-kappaB signaling. Immunity 36: 742-754, 2012.
-
(2012)
Immunity
, vol.36
, pp. 742-754
-
-
Allen, I.C.1
Wilson, J.E.2
Schneider, M.3
Lich, J.D.4
Roberts, R.A.5
Arthur, J.C.6
Woodford, R.M.7
Davis, B.K.8
Uronis, J.M.9
Herfarth, H.H.10
Jobin, C.11
Rogers, A.B.12
Ting, J.P.13
-
3
-
-
84865130689
-
NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens
-
Anand PK, Malireddi RK, Lukens JR, Vogel P, Bertin J, Lamkanfi M, Kanneganti TD. NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens. Nature 488: 389-393, 2012.
-
(2012)
Nature
, vol.488
, pp. 389-393
-
-
Anand, P.K.1
Malireddi, R.K.2
Lukens, J.R.3
Vogel, P.4
Bertin, J.5
Lamkanfi, M.6
Kanneganti, T.D.7
-
4
-
-
22244465576
-
Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-kappaB activation in muramyl dipeptide recognition
-
Barnich N, Aguirre JE, Reinecker HC, Xavier R, Podolsky DK. Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-kappaB activation in muramyl dipeptide recognition. J Cell Biol 170: 21-26, 2005.
-
(2005)
J Cell Biol
, vol.170
, pp. 21-26
-
-
Barnich, N.1
Aguirre, J.E.2
Reinecker, H.C.3
Xavier, R.4
Podolsky, D.K.5
-
5
-
-
20444486755
-
GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of antibacterial function in intestinal epithelial cells
-
Barnich N, Hisamatsu T, Aguirre JE, Xavier R, Reinecker HC, Podolsky DK. GRIM-19 interacts with nucleotide oligomerization domain 2 and serves as downstream effector of antibacterial function in intestinal epithelial cells. J Biol Chem 280: 19021-19026, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 19021-19026
-
-
Barnich, N.1
Hisamatsu, T.2
Aguirre, J.E.3
Xavier, R.4
Reinecker, H.C.5
Podolsky, D.K.6
-
6
-
-
34848928674
-
CARD15/NOD2 is required for Peyer’s patches homeostasis in mice
-
Barreau F, Meinzer U, Chareyre F, Berrebi D, Niwa-Kawakita M, Dussaillant M, Foligne B, Ollendorff V, Heyman M, Bonacorsi S, Lesuffleur T, Sterkers G, Giovannini M, Hugot JP. CARD15/NOD2 is required for Peyer’s patches homeostasis in mice. PLos One 2: e523, 2007.
-
(2007)
Plos One
, vol.2
-
-
Barreau, F.1
Meinzer, U.2
Chareyre, F.3
Berrebi, D.4
Niwa-Kawakita, M.5
Dussaillant, M.6
Foligne, B.7
Ollendorff, V.8
Heyman, M.9
Bonacorsi, S.10
Lesuffleur, T.11
Sterkers, G.12
Giovannini, M.13
Hugot, J.P.14
-
7
-
-
0037408494
-
Pretreatment of mice with streptomycin provides a Salmonella enterica serovar Typhimurium colitis model that allows analysis of both pathogen and host
-
Barthel M, Hapfelmeier S, Quintanilla-Martinez L, Kremer M, Rohde M, Hogardt M, Pfeffer K, Russmann H, Hardt WD. Pretreatment of mice with streptomycin provides a Salmonella enterica serovar Typhimurium colitis model that allows analysis of both pathogen and host. Infect Immun 71: 2839-2858, 2003.
-
(2003)
Infect Immun
, vol.71
, pp. 2839-2858
-
-
Barthel, M.1
Hapfelmeier, S.2
Quintanilla-Martinez, L.3
Kremer, M.4
Rohde, M.5
Hogardt, M.6
Pfeffer, K.7
Russmann, H.8
Hardt, W.D.9
-
8
-
-
77956128040
-
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome
-
Bauer C, Duewell P, Mayer C, Lehr HA, Fitzgerald KA, Dauer M, Tschopp J, Endres S, Latz E, Schnurr M. Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome. Gut 59: 1192-1199, 2010.
-
(2010)
Gut
, vol.59
, pp. 1192-1199
-
-
Bauer, C.1
Duewell, P.2
Mayer, C.3
Lehr, H.A.4
Fitzgerald, K.A.5
Dauer, M.6
Tschopp, J.7
Endres, S.8
Latz, E.9
Schnurr, M.10
-
9
-
-
70249138036
-
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
-
Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, MacDonald K, Speert D, Fernandes-Alnemri T, Wu J, Monks BG, Fitzgerald KA, Hornung V, Latz E. Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression. J Immunol 183: 787-791, 2009.
-
(2009)
J Immunol
, vol.183
, pp. 787-791
-
-
Bauernfeind, F.G.1
Horvath, G.2
Stutz, A.3
Alnemri, E.S.4
Macdonald, K.5
Speert, D.6
Fernandes-Alnemri, T.7
Wu, J.8
Monks, B.G.9
Fitzgerald, K.A.10
Hornung, V.11
Latz, E.12
-
10
-
-
84875246938
-
Regulation of intestinal microbiota by the NLR protein family
-
Biswas A, Kobayashi KS. Regulation of intestinal microbiota by the NLR protein family. Int Immunol 25: 207-214, 2013.
-
(2013)
Int Immunol
, vol.25
, pp. 207-214
-
-
Biswas, A.1
Kobayashi, K.S.2
-
11
-
-
77957047689
-
Induction and rescue of Nod2-dependent Th1- driven granulomatous inflammation of the ileum
-
Biswas A, Liu YJ, Hao L, Mizoguchi A, Salzman NH, Bevins CL, Kobayashi KS. Induction and rescue of Nod2-dependent Th1- driven granulomatous inflammation of the ileum. Proc Natl Acad Sci USA 107: 14739-14744, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14739-14744
-
-
Biswas, A.1
Liu, Y.J.2
Hao, L.3
Mizoguchi, A.4
Salzman, N.H.5
Bevins, C.L.6
Kobayashi, K.S.7
-
12
-
-
77955390094
-
Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella
-
Broz P, Newton K, Lamkanfi M, Mariathasan S, Dixit VM, Monack DM. Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella. J Exp Med 207: 1745-1755, 2010.
-
(2010)
J Exp Med
, vol.207
, pp. 1745-1755
-
-
Broz, P.1
Newton, K.2
Lamkanfi, M.3
Mariathasan, S.4
Dixit, V.M.5
Monack, D.M.6
-
13
-
-
84866446076
-
Innate immune response to Salmonella typhimurium, a model enteric pathogen
-
Broz P, Ohlson MB, Monack DM. Innate immune response to Salmonella typhimurium, a model enteric pathogen. Gut Microbes 3: 62-70, 2012.
-
(2012)
Gut Microbes
, vol.3
, pp. 62-70
-
-
Broz, P.1
Ohlson, M.B.2
Monack, D.M.3
-
14
-
-
84859862381
-
Cytosolic flagellin receptor NLRC4 protects mice against mucosal and systemic challenges
-
Carvalho FA, Nalbantoglu I, Aitken JD, Uchiyama R, Su Y, Doho GH, Vijay-Kumar M, Gewirtz AT. Cytosolic flagellin receptor NLRC4 protects mice against mucosal and systemic challenges. Mucosal Immunol 5: 288-298, 2012.
-
(2012)
Mucosal Immunol
, vol.5
, pp. 288-298
-
-
Carvalho, F.A.1
Nalbantoglu, I.2
Aitken, J.D.3
Uchiyama, R.4
Su, Y.5
Doho, G.H.6
Vijay-Kumar, M.7
Gewirtz, A.T.8
-
15
-
-
79952230127
-
Crohn disease: Associated adherent- invasive E coli bacteria target mouse and human Peyer’s patches via long polar fimbriae
-
Chassaing B, Rolhion N, de Vallee A, Salim SY, Prorok-Hamon M, Neut C, Campbell BJ, Soderholm JD, Hugot JP, Colombel JF, Darfeuille-Michaud A. Crohn disease: associated adherent- invasive E coli bacteria target mouse and human Peyer’s patches via long polar fimbriae. J Clin Invest 121: 966-975, 2011.
-
(2011)
J Clin Invest
, vol.121
, pp. 966-975
-
-
Chassaing, B.1
Rolhion, N.2
De Vallee, A.3
Salim, S.Y.4
Prorok-Hamon, M.5
Neut, C.6
Campbell, B.J.7
Soderholm, J.D.8
Hugot, J.P.9
Colombel, J.F.10
Darfeuille-Michaud, A.11
-
16
-
-
79959540809
-
A functional role for Nlrp6 in intestinal inflammation and tumorigenesis
-
Chen GY, Liu M, Wang F, Bertin J, Nunez G. A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. J Immunol 186: 7187-7194, 2011.
-
(2011)
J Immunol
, vol.186
, pp. 7187-7194
-
-
Chen, G.Y.1
Liu, M.2
Wang, F.3
Bertin, J.4
Nunez, G.5
-
17
-
-
57749094105
-
The innate immune receptor Nod1 protects the intestine from inflammation- induced tumorigenesis
-
Chen GY, Shaw MH, Redondo G, Nunez G. The innate immune receptor Nod1 protects the intestine from inflammation- induced tumorigenesis. Cancer Res 68: 10060-10067, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 10060-10067
-
-
Chen, G.Y.1
Shaw, M.H.2
Redondo, G.3
Nunez, G.4
-
18
-
-
84913603865
-
Salmonella enterica serovar Typhimurium _msbB 1 triggers exacerbated inflammation in Nod2 deficient mice
-
Claes AK, Steck N, Schultz D, Zahringer U, Lipinski S, Rosenstiel P, Geddes K, Philpott DJ, Heine H, Grassl GA. Salmonella enterica serovar Typhimurium _msbB 1 triggers exacerbated inflammation in Nod2 deficient mice. PLos One 9: e113645, 2014.
-
(2014)
Plos One
, vol.9
-
-
Claes, A.K.1
Steck, N.2
Schultz, D.3
Zahringer, U.4
Lipinski, S.5
Rosenstiel, P.6
Geddes, K.7
Philpott, D.J.8
Heine, H.9
Grassl, G.A.10
-
19
-
-
77956025260
-
New insights into the regulation of signalling by toll-like receptors and nod-like receptors
-
Coll RC, O’Neill LA. New insights into the regulation of signalling by toll-like receptors and nod-like receptors. J Innate Immun 2: 406-421, 2010.
-
(2010)
J Innate Immun
, vol.2
, pp. 406-421
-
-
Coll, R.C.1
O’neill, L.A.2
-
20
-
-
84873372079
-
NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer
-
Couturier-Maillard A, Secher T, Rehman A, Normand S, De Arcangelis A, Haesler R, Huot L, Grandjean T, Bressenot A, Delanoye-Crespin A, Gaillot O, Schreiber S, Lemoine Y, Ryffel B, Hot D, Nunez G, Chen G, Rosenstiel P, Chamaillard M. NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer. J Clin Invest 123: 700-711, 2013.
-
(2013)
J Clin Invest
, vol.123
, pp. 700-711
-
-
Couturier-Maillard, A.1
Secher, T.2
Rehman, A.3
Normand, S.4
De Arcangelis, A.5
Haesler, R.6
Huot, L.7
Grandjean, T.8
Bressenot, A.9
Delanoye-Crespin, A.10
Gaillot, O.11
Schreiber, S.12
Lemoine, Y.13
Ryffel, B.14
Hot, D.15
Nunez, G.16
Chen, G.17
Rosenstiel, P.18
Chamaillard, M.19
-
21
-
-
77953302756
-
The genetics of NOD-like receptors in Crohn’s disease
-
Cummings JR, Cooney RM, Clarke G, Beckly J, Geremia A, Pathan S, Hancock L, Guo C, Cardon LR, Jewell DP. The genetics of NOD-like receptors in Crohn’s disease. Tissue Antigens 76: 48-56, 2010.
-
(2010)
Tissue Antigens
, vol.76
, pp. 48-56
-
-
Cummings, J.R.1
Cooney, R.M.2
Clarke, G.3
Beckly, J.4
Geremia, A.5
Pathan, S.6
Hancock, L.7
Guo, C.8
Cardon, L.R.9
Jewell, D.P.10
-
22
-
-
84881048250
-
Mitochondriatargeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines
-
Dashdorj A, Jyothi KR, Lim S, Jo A, Nguyen MN, Ha J, Yoon KS, Kim HJ, Park JH, Murphy MP, Kim SS. Mitochondriatargeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines. BMC Med 11: 178, 2013.
-
(2013)
BMC Med
, vol.11
-
-
Dashdorj, A.1
Jyothi, K.R.2
Lim, S.3
Jo, A.4
Nguyen, M.N.5
Ha, J.6
Yoon, K.S.7
Kim, H.J.8
Park, J.H.9
Murphy, M.P.10
Kim, S.S.11
-
23
-
-
43249125839
-
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
-
Dostert C, Petrilli V, Van Bruggen R, Steele C, Mossman BT, Tschopp J. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320: 674-677, 2008.
-
(2008)
Science
, vol.320
, pp. 674-677
-
-
Dostert, C.1
Petrilli, V.2
Van Bruggen, R.3
Steele, C.4
Mossman, B.T.5
Tschopp, J.6
-
24
-
-
53149153194
-
Beta-PIX and Rac1 GTPase mediate trafficking and negative regulation of NOD2
-
Eitel J, Krull M, Hocke AC, N’Guessan PD, Zahlten J, Schmeck B, Slevogt H, Hippenstiel S, Suttorp N, Opitz B. Beta-PIX and Rac1 GTPase mediate trafficking and negative regulation of NOD2. J Immunol 181: 2664-2671, 2008.
-
(2008)
J Immunol
, vol.181
, pp. 2664-2671
-
-
Eitel, J.1
Krull, M.2
Hocke, A.C.3
N’guessan, P.D.4
Zahlten, J.5
Schmeck, B.6
Slevogt, H.7
Hippenstiel, S.8
Suttorp, N.9
Opitz, B.10
-
25
-
-
79957576718
-
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
-
Elinav E, Strowig T, Kau AL, Henao-Mejia J, Thaiss CA, Booth CJ, Peaper DR, Bertin J, Eisenbarth SC, Gordon JI, Flavell RA. NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Cell 145: 745-757, 2011.
-
(2011)
Cell
, vol.145
, pp. 745-757
-
-
Elinav, E.1
Strowig, T.2
Kau, A.L.3
Henao-Mejia, J.4
Thaiss, C.A.5
Booth, C.J.6
Peaper, D.R.7
Bertin, J.8
Eisenbarth, S.C.9
Gordon, J.I.10
Flavell, R.A.11
-
26
-
-
33744464740
-
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages
-
Franchi L, Amer A, Body-Malapel M, Kanneganti TD, Ozoren N, Jagirdar R, Inohara N, Vandenabeele P, Bertin J, Coyle A, Grant EP, Nunez G. Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages. Nat Immunol 7: 576-582, 2006.
-
(2006)
Nat Immunol
, vol.7
, pp. 576-582
-
-
Franchi, L.1
Amer, A.2
Body-Malapel, M.3
Kanneganti, T.D.4
Ozoren, N.5
Jagirdar, R.6
Inohara, N.7
Vandenabeele, P.8
Bertin, J.9
Coyle, A.10
Grant, E.P.11
Nunez, G.12
-
27
-
-
84859911615
-
NLRC4-driven production of IL-1beta discriminates between pathogenic and commensal bacteria and promotes host intestinal defense
-
Franchi L, Kamada N, Nakamura Y, Burberry A, Kuffa P, Suzuki S, Shaw MH, Kim YG, Nunez G. NLRC4-driven production of IL-1beta discriminates between pathogenic and commensal bacteria and promotes host intestinal defense. Nat Immunol 13: 449-456, 2012.
-
(2012)
Nat Immunol
, vol.13
, pp. 449-456
-
-
Franchi, L.1
Kamada, N.2
Nakamura, Y.3
Burberry, A.4
Kuffa, P.5
Suzuki, S.6
Shaw, M.H.7
Kim, Y.G.8
Nunez, G.9
-
28
-
-
58049200723
-
Function of Nod-like receptors in microbial recognition and host defense
-
Franchi L, Warner N, Viani K, Nunez G. Function of Nod-like receptors in microbial recognition and host defense. Immunol Rev 227: 106-128, 2009.
-
(2009)
Immunol Rev
, vol.227
, pp. 106-128
-
-
Franchi, L.1
Warner, N.2
Viani, K.3
Nunez, G.4
-
29
-
-
33750344673
-
No association between the functional CARD4 insertion/deletion polymorphism and inflammatory bowel diseases in the German population
-
Franke A, Ruether A, Wedemeyer N, Karlsen TH, Nebel A, Schreiber S. No association between the functional CARD4 insertion/deletion polymorphism and inflammatory bowel diseases in the German population. Gut 55: 1679-1680, 2006.
-
(2006)
Gut
, vol.55
, pp. 1679-1680
-
-
Franke, A.1
Ruether, A.2
Wedemeyer, N.3
Karlsen, T.H.4
Nebel, A.5
Schreiber, S.6
-
30
-
-
57149093623
-
GEF-H1 mediated control of NOD1 dependent NF-kappaB activation by Shigella effectors
-
Fukazawa A, Alonso C, Kurachi K, Gupta S, Lesser CF, McCormick BA, Reinecker HC. GEF-H1 mediated control of NOD1 dependent NF-kappaB activation by Shigella effectors. PLoS Pathog 4: e1000228, 2008.
-
(2008)
Plos Pathog
, vol.4
-
-
Fukazawa, A.1
Alonso, C.2
Kurachi, K.3
Gupta, S.4
Lesser, C.F.5
McCormick, B.A.6
Reinecker, H.C.7
-
31
-
-
78649957904
-
Nod1 and Nod2 regulation of inflammation in the Salmonella colitis model
-
Geddes K, Rubino S, Streutker C, Cho JH, Magalhaes JG, Le Bourhis L, Selvanantham T, Girardin SE, Philpott DJ. Nod1 and Nod2 regulation of inflammation in the Salmonella colitis model. Infect Immun 78: 5107-5115, 2010.
-
(2010)
Infect Immun
, vol.78
, pp. 5107-5115
-
-
Geddes, K.1
Rubino, S.2
Streutker, C.3
Cho, J.H.4
Magalhaes, J.G.5
Le Bourhis, L.6
Selvanantham, T.7
Girardin, S.E.8
Philpott, D.J.9
-
32
-
-
79960131814
-
Identification of an innate T helper type 17 response to intestinal bacterial pathogens
-
Geddes K, Rubino SJ, Magalhaes JG, Streutker C, Le Bourhis L, Cho JH, Robertson SJ, Kim CJ, Kaul R, Philpott DJ, Girardin SE. Identification of an innate T helper type 17 response to intestinal bacterial pathogens. Nat Med 17: 837-844, 2011.
-
(2011)
Nat Med
, vol.17
, pp. 837-844
-
-
Geddes, K.1
Rubino, S.J.2
Magalhaes, J.G.3
Streutker, C.4
Le Bourhis, L.5
Cho, J.H.6
Robertson, S.J.7
Kim, C.J.8
Kaul, R.9
Philpott, D.J.10
Girardin, S.E.11
-
33
-
-
0038615855
-
Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan
-
Girardin SE, Boneca IG, Carneiro LA, Antignac A, Jehanno M, Viala J, Tedin K, Taha MK, Labigne A, Zahringer U, Coyle AJ, DiStefano PS, Bertin J, Sansonetti PJ, Philpott DJ. Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan. Science 300: 1584-1587, 2003.
-
(2003)
Science
, vol.300
, pp. 1584-1587
-
-
Girardin, S.E.1
Boneca, I.G.2
Carneiro, L.A.3
Antignac, A.4
Jehanno, M.5
Viala, J.6
Tedin, K.7
Taha, M.K.8
Labigne, A.9
Zahringer, U.10
Coyle, A.J.11
Distefano, P.S.12
Bertin, J.13
Sansonetti, P.J.14
Philpott, D.J.15
-
34
-
-
0012722659
-
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
-
Girardin SE, Boneca IG, Viala J, Chamaillard M, Labigne A, Thomas G, Philpott DJ, Sansonetti PJ. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J Biol Chem 278: 8869-8872, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 8869-8872
-
-
Girardin, S.E.1
Boneca, I.G.2
Viala, J.3
Chamaillard, M.4
Labigne, A.5
Thomas, G.6
Philpott, D.J.7
Sansonetti, P.J.8
-
35
-
-
17944380130
-
CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri
-
Girardin SE, Tournebize R, Mavris M, Page AL, Li X, Stark GR, Bertin J, DiStefano PS, Yaniv M, Sansonetti PJ, Philpott DJ. CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri. EMBO Rep 2: 736-742, 2001.
-
(2001)
EMBO Rep
, vol.2
, pp. 736-742
-
-
Girardin, S.E.1
Tournebize, R.2
Mavris, M.3
Page, A.L.4
Li, X.5
Stark, G.R.6
Bertin, J.7
Distefano, P.S.8
Yaniv, M.9
Sansonetti, P.J.10
Philpott, D.J.11
-
36
-
-
39749115051
-
Chronic enteric salmonella infection in mice leads to severe and persistent intestinal fibrosis
-
Grassl GA, Valdez Y, Bergstrom KS, Vallance BA, Finlay BB. Chronic enteric salmonella infection in mice leads to severe and persistent intestinal fibrosis. Gastroenterology 134: 768-780, 2008.
-
(2008)
Gastroenterology
, vol.134
, pp. 768-780
-
-
Grassl, G.A.1
Valdez, Y.2
Bergstrom, K.S.3
Vallance, B.A.4
Finlay, B.B.5
-
37
-
-
84865434771
-
The innate immune protein Nod2 binds directly to MDP, a bacterial cell wall fragment
-
Grimes CL, Ariyananda Lde Z, Melnyk JE, O’Shea EK. The innate immune protein Nod2 binds directly to MDP, a bacterial cell wall fragment. J Am Chem Soc 134: 13535-13537, 2012.
-
(2012)
J am Chem Soc
, vol.134
, pp. 13535-13537
-
-
Grimes, C.L.1
Ariyananda Lde, Z.2
Melnyk, J.E.3
O’shea, E.K.4
-
38
-
-
77749270973
-
Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor
-
Harder J, Franchi L, Munoz-Planillo R, Park JH, Reimer T, Nunez G. Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor. J Immunol 183: 5823-5829, 2009.
-
(2009)
J Immunol
, vol.183
, pp. 5823-5829
-
-
Harder, J.1
Franchi, L.2
Munoz-Planillo, R.3
Park, J.H.4
Reimer, T.5
Nunez, G.6
-
39
-
-
79955048935
-
Nucleotide- binding oligomerization domain 1 mediates recognition of Clostridium difficile and induces neutrophil recruitment and protection against the pathogen
-
Hasegawa M, Yamazaki T, Kamada N, Tawaratsumida K, Kim YG, Nunez G, Inohara N. Nucleotide- binding oligomerization domain 1 mediates recognition of Clostridium difficile and induces neutrophil recruitment and protection against the pathogen. J Immunol 186: 4872-4880, 2011.
-
(2011)
J Immunol
, vol.186
, pp. 4872-4880
-
-
Hasegawa, M.1
Yamazaki, T.2
Kamada, N.3
Tawaratsumida, K.4
Kim, Y.G.5
Nunez, G.6
Inohara, N.7
-
40
-
-
79955846705
-
NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis
-
Hirota SA, Ng J, Lueng A, Khajah M, Parhar K, Li Y, Lam V, Potentier MS, Ng K, Bawa M, McCafferty DM, Rioux KP, Ghosh S, Xavier RJ, Colgan SP, Tschopp J, Muruve D, MacDonald JA, Beck PL. NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis. Inflamm Bowel Dis 17: 1359-1372, 2011.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 1359-1372
-
-
Hirota, S.A.1
Ng, J.2
Lueng, A.3
Khajah, M.4
Parhar, K.5
Li, Y.6
Lam, V.7
Potentier, M.S.8
Ng, K.9
Bawa, M.10
McCafferty, D.M.11
Rioux, K.P.12
Ghosh, S.13
Xavier, R.J.14
Colgan, S.P.15
Tschopp, J.16
Muruve, D.17
Macdonald, J.A.18
Beck, P.L.19
-
41
-
-
0037380969
-
CARD15/ NOD2 functions as an antibacterial factor in human intestinal epithelial cells
-
Hisamatsu T, Suzuki M, Reinecker HC, Nadeau WJ, McCormick BA, Podolsky DK. CARD15/ NOD2 functions as an antibacterial factor in human intestinal epithelial cells. Gastroenterology 124: 993-1000, 2003.
-
(2003)
Gastroenterology
, vol.124
, pp. 993-1000
-
-
Hisamatsu, T.1
Suzuki, M.2
Reinecker, H.C.3
Nadeau, W.J.4
McCormick, B.A.5
Podolsky, D.K.6
-
42
-
-
77749304034
-
Critical functions of priming and lysosomal damage for NLRP3 activation
-
Hornung V, Latz E. Critical functions of priming and lysosomal damage for NLRP3 activation. Eur J Immunol 40: 620-623, 2010.
-
(2010)
Eur J Immunol
, vol.40
, pp. 620-623
-
-
Hornung, V.1
Latz, E.2
-
43
-
-
78650735879
-
Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4
-
Hu B, Elinav E, Huber S, Booth CJ, Strowig T, Jin C, Eisenbarth SC, Flavell RA. Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4. Proc Natl Acad Sci USA 107: 21635-21640, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 21635-21640
-
-
Hu, B.1
Elinav, E.2
Huber, S.3
Booth, C.J.4
Strowig, T.5
Jin, C.6
Eisenbarth, S.C.7
Flavell, R.A.8
-
44
-
-
84878971321
-
Microbiota-induced activation of epithelial IL-6 signaling links inflammasome- driven inflammation with transmissible cancer
-
Hu B, Elinav E, Huber S, Strowig T, Hao L, Hafemann A, Jin C, Wunderlich C, Wunderlich T, Eisenbarth SC, Flavell RA. Microbiota-induced activation of epithelial IL-6 signaling links inflammasome- driven inflammation with transmissible cancer. Proc Natl Acad Sci USA 110: 9862-9867, 2013.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 9862-9867
-
-
Hu, B.1
Elinav, E.2
Huber, S.3
Strowig, T.4
Hao, L.5
Hafemann, A.6
Jin, C.7
Wunderlich, C.8
Wunderlich, T.9
Eisenbarth, S.C.10
Flavell, R.A.11
-
45
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn’s disease
-
Hugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J, Almer S, Tysk C, O’Morain CA, Gassull M, Binder V, Finkel Y, Cortot A, Modigliani R, Laurent-Puig P, Gower-Rousseau C, Macry J, Colombel JF, Sahbatou M, Thomas G. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn’s disease. Nature 411: 599-603, 2001.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cezard, J.P.5
Belaiche, J.6
Almer, S.7
Tysk, C.8
O’morain, C.A.9
Gassull, M.10
Binder, V.11
Finkel, Y.12
Cortot, A.13
Modigliani, R.14
Laurent-Puig, P.15
Gower-Rousseau, C.16
Macry, J.17
Colombel, J.F.18
Sahbatou, M.19
Thomas, G.20
more..
-
46
-
-
0038624558
-
NODs: Intracellular proteins involved in inflammation and apoptosis
-
Inohara N, Nunez G. NODs: intracellular proteins involved in inflammation and apoptosis. Nat Rev Immunol 3: 371-382, 2003.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 371-382
-
-
Inohara, N.1
Nunez, G.2
-
47
-
-
84901025110
-
The immune receptor NOD1 and kinase RIP2 interact with bacterial peptidoglycan on early endosomes to promote autophagy and inflammatory signaling
-
Irving AT, Mimuro H, Kufer TA, Lo C, Wheeler R, Turner LJ, Thomas BJ, Malosse C, Gantier MP, Casillas LN, Votta BJ, Bertin J, Boneca IG, Sasakawa C, Philpott DJ, Ferrero RL, Kaparakis- Liaskos M. The immune receptor NOD1 and kinase RIP2 interact with bacterial peptidoglycan on early endosomes to promote autophagy and inflammatory signaling. Cell Host Microbe 15: 623-635, 2014.
-
(2014)
Cell Host Microbe
, vol.15
, pp. 623-635
-
-
Irving, A.T.1
Mimuro, H.2
Kufer, T.A.3
Lo, C.4
Wheeler, R.5
Turner, L.J.6
Thomas, B.J.7
Malosse, C.8
Gantier, M.P.9
Casillas, L.N.10
Votta, B.J.11
Bertin, J.12
Boneca, I.G.13
Sasakawa, C.14
Philpott, D.J.15
Ferrero, R.L.16
Kaparakis- Liaskos, M.17
-
48
-
-
0037709366
-
Cloning, sequencing and expression analysis of the mouse NOD2/CARD15 gene
-
Iwanaga Y, Davey MP, Martin TM, Planck SR, DePriest ML, Baugh MM, Suing CM, Rosenbaum JT. Cloning, sequencing and expression analysis of the mouse NOD2/CARD15 gene. Inflamm Res 52: 272-276, 2003.
-
(2003)
Inflamm Res
, vol.52
, pp. 272-276
-
-
Iwanaga, Y.1
Davey, M.P.2
Martin, T.M.3
Planck, S.R.4
Depriest, M.L.5
Baugh, M.M.6
Suing, C.M.7
Rosenbaum, J.T.8
-
49
-
-
28244459680
-
Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kappaB-driven protein synthesis
-
Kahlenberg JM, Lundberg KC, Kertesy SB, Qu Y, Dubyak GR. Potentiation of caspase-1 activation by the P2X7 receptor is dependent on TLR signals and requires NF-kappaB-driven protein synthesis. J Immunol 175: 7611-7622, 2005.
-
(2005)
J Immunol
, vol.175
, pp. 7611-7622
-
-
Kahlenberg, J.M.1
Lundberg, K.C.2
Kertesy, S.B.3
Qu, Y.4
Dubyak, G.R.5
-
50
-
-
84876282419
-
Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1
-
Keestra AM, Winter MG, Auburger JJ, Frassle SP, Xavier MN, Winter SE, Kim A, Poon V, Ravesloot MM, Waldenmaier JF, Tsolis RM, Eigenheer RA, Baumler AJ. Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1. Nature 496: 233-237, 2013.
-
(2013)
Nature
, vol.496
, pp. 233-237
-
-
Keestra, A.M.1
Winter, M.G.2
Auburger, J.J.3
Frassle, S.P.4
Xavier, M.N.5
Winter, S.E.6
Kim, A.7
Poon, V.8
Ravesloot, M.M.9
Waldenmaier, J.F.10
Tsolis, R.M.11
Eigenheer, R.A.12
Baumler, A.J.13
-
51
-
-
79956319462
-
The Nod2 sensor promotes intestinal pathogen eradication via the chemokine CCL2-dependent recruitment of inflammatory monocytes
-
Kim YG, Kamada N, Shaw MH, Warner N, Chen GY, Franchi L, Nunez G. The Nod2 sensor promotes intestinal pathogen eradication via the chemokine CCL2-dependent recruitment of inflammatory monocytes. Immunity 34: 769-780, 2011.
-
(2011)
Immunity
, vol.34
, pp. 769-780
-
-
Kim, Y.G.1
Kamada, N.2
Shaw, M.H.3
Warner, N.4
Chen, G.Y.5
Franchi, L.6
Nunez, G.7
-
52
-
-
80053055841
-
Cutting edge: Crohn’s disease- associated Nod2 mutation limits production of proinflammatory cytokines to protect the host from Enterococcus faecalis-induced lethality
-
Kim YG, Shaw MH, Warner N, Park JH, Chen F, Ogura Y, Nunez G. Cutting edge: Crohn’s disease- associated Nod2 mutation limits production of proinflammatory cytokines to protect the host from Enterococcus faecalis-induced lethality. J Immunol 187: 2849-2852, 2011.
-
(2011)
J Immunol
, vol.187
, pp. 2849-2852
-
-
Kim, Y.G.1
Shaw, M.H.2
Warner, N.3
Park, J.H.4
Chen, F.5
Ogura, Y.6
Nunez, G.7
-
53
-
-
84911992879
-
Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens
-
Knodler LA, Crowley SM, Sham HP, Yang H, Wrande M, Ma C, Ernst RK, Steele-Mortimer O, Celli J, Vallance BA. Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens. Cell Host Microbe 16: 249-256, 2014.
-
(2014)
Cell Host Microbe
, vol.16
, pp. 249-256
-
-
Knodler, L.A.1
Crowley, S.M.2
Sham, H.P.3
Yang, H.4
Wrande, M.5
Ma, C.6
Ernst, R.K.7
Steele-Mortimer, O.8
Celli, J.9
Vallance, B.A.10
-
54
-
-
13244292161
-
Nod2- dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi KS, Chamaillard M, Ogura Y, Henegariu O, Inohara N, Nunez G, Flavell RA. Nod2- dependent regulation of innate and adaptive immunity in the intestinal tract. Science 307: 731-734, 2005.
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
Henegariu, O.4
Inohara, N.5
Nunez, G.6
Flavell, R.A.7
-
55
-
-
80053379974
-
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
-
Kofoed EM, Vance RE. Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity. Nature 477: 592-595, 2011.
-
(2011)
Nature
, vol.477
, pp. 592-595
-
-
Kofoed, E.M.1
Vance, R.E.2
-
56
-
-
42149148610
-
Signal transduction pathways used by NLR-type innate immune receptors
-
Kufer TA. Signal transduction pathways used by NLR-type innate immune receptors. Mol Biosyst 4: 380-386, 2008.
-
(2008)
Mol Biosyst
, vol.4
, pp. 380-386
-
-
Kufer, T.A.1
-
58
-
-
38049177193
-
The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction
-
Kufer TA, Kremmer E, Adam AC, Philpott DJ, Sansonetti PJ. The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction. Cell Microbiol 10: 477-486, 2008.
-
(2008)
Cell Microbiol
, vol.10
, pp. 477-486
-
-
Kufer, T.A.1
Kremmer, E.2
Adam, A.C.3
Philpott, D.J.4
Sansonetti, P.J.5
-
59
-
-
33646941554
-
Role for erbin in bacterial activation of Nod2
-
Kufer TA, Kremmer E, Banks DJ, Philpott DJ. Role for erbin in bacterial activation of Nod2. Infect Immun 74: 3115-3124, 2006.
-
(2006)
Infect Immun
, vol.74
, pp. 3115-3124
-
-
Kufer, T.A.1
Kremmer, E.2
Banks, D.J.3
Philpott, D.J.4
-
60
-
-
34247574122
-
Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response
-
Kummer JA, Broekhuizen R, Everett H, Agostini L, Kuijk L, Martinon F, van Bruggen R, Tschopp J. Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response. J Histochem Cytochem 55: 443-452, 2007.
-
(2007)
J Histochem Cytochem
, vol.55
, pp. 443-452
-
-
Kummer, J.A.1
Broekhuizen, R.2
Everett, H.3
Agostini, L.4
Kuijk, L.5
Martinon, F.6
Van Bruggen, R.7
Tschopp, J.8
-
61
-
-
84901310586
-
Mechanisms and functions of inflammasomes
-
Lamkanfi M, Dixit VM. Mechanisms and functions of inflammasomes. Cell 157: 1013-1022, 2014.
-
(2014)
Cell
, vol.157
, pp. 1013-1022
-
-
Lamkanfi, M.1
Dixit, V.M.2
-
62
-
-
80052230551
-
L-Ala-gamma-D-Glu-meso-diaminopimelic acid (DAP) interacts directly with leucine-rich region domain of nucleotide-binding oligomerization domain 1, increasing phosphorylation activity of receptor-interacting serine/threonine-protein kinase 2 and its interaction with nucleotide-binding oligomerization domain 1
-
Laroui H, Yan Y, Narui Y, Ingersoll SA, Ayyadurai S, Charania MA, Zhou F, Wang B, Salaita K, Sitaraman SV, Merlin D. L-Ala-gamma-D-Glu-meso-diaminopimelic acid (DAP) interacts directly with leucine-rich region domain of nucleotide-binding oligomerization domain 1, increasing phosphorylation activity of receptor-interacting serine/threonine-protein kinase 2 and its interaction with nucleotide-binding oligomerization domain 1. J Biol Chem 286: 31003-31013, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 31003-31013
-
-
Laroui, H.1
Yan, Y.2
Narui, Y.3
Ingersoll, S.A.4
Ayyadurai, S.5
Charania, M.A.6
Zhou, F.7
Wang, B.8
Salaita, K.9
Sitaraman, S.V.10
Merlin, D.11
-
63
-
-
70349433671
-
Role of Nod1 in mucosal dendritic cells during Salmonella pathogenicity island 1-independent Salmonella enterica serovar Typhimurium infection
-
Le Bourhis L, Magalhaes JG, Selvanantham T, Travassos LH, Geddes K, Fritz JH, Viala J, Tedin K, Girardin SE, Philpott DJ. Role of Nod1 in mucosal dendritic cells during Salmonella pathogenicity island 1-independent Salmonella enterica serovar Typhimurium infection. Infect Immun 77: 4480-4486, 2009.
-
(2009)
Infect Immun
, vol.77
, pp. 4480-4486
-
-
Le Bourhis, L.1
Magalhaes, J.G.2
Selvanantham, T.3
Travassos, L.H.4
Geddes, K.5
Fritz, J.H.6
Viala, J.7
Tedin, K.8
Girardin, S.E.9
Philpott, D.J.10
-
64
-
-
69949125920
-
PH-dependent internalization of muramyl peptides from early endosomes enables Nod1 and Nod2 signaling
-
Lee J, Tattoli I, Wojtal KA, Vavricka SR, Philpott DJ, Girardin SE. pH-dependent internalization of muramyl peptides from early endosomes enables Nod1 and Nod2 signaling. J Biol Chem 284: 23818-23829, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 23818-23829
-
-
Lee, J.1
Tattoli, I.2
Wojtal, K.A.3
Vavricka, S.R.4
Philpott, D.J.5
Girardin, S.E.6
-
65
-
-
34248226821
-
Modulation of Nod2-dependent NF-kappaB signaling by the actin cytoskeleton
-
Legrand-Poels S, Kustermans G, Bex F, Kremmer E, Kufer TA, Piette J. Modulation of Nod2-dependent NF-kappaB signaling by the actin cytoskeleton. J Cell Sci 120: 1299-1310, 2007.
-
(2007)
J Cell Sci
, vol.120
, pp. 1299-1310
-
-
Legrand-Poels, S.1
Kustermans, G.2
Bex, F.3
Kremmer, E.4
Kufer, T.A.5
Piette, J.6
-
66
-
-
84871837817
-
RNAi screening identifies mediators of NOD2 signaling: Implications for spatial specificity of MDP recognition
-
Lipinski S, Grabe N, Jacobs G, Billmann-Born S, Till A, Hasler R, Aden K, Paulsen M, Arlt A, Kraemer L, Hagemann N, Erdmann KS, Schreiber S, Rosenstiel P. RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition. Proc Natl Acad Sci USA 109: 21426-21431, 2012.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 21426-21431
-
-
Lipinski, S.1
Grabe, N.2
Jacobs, G.3
Billmann-Born, S.4
Till, A.5
Hasler, R.6
Aden, K.7
Paulsen, M.8
Arlt, A.9
Kraemer, L.10
Hagemann, N.11
Erdmann, K.S.12
Schreiber, S.13
Rosenstiel, P.14
-
67
-
-
70350380878
-
DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses
-
Lipinski S, Till A, Sina C, Arlt A, Grasberger H, Schreiber S, Rosenstiel P. DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses. J Cell Sci 122: 3522-3530, 2009.
-
(2009)
J Cell Sci
, vol.122
, pp. 3522-3530
-
-
Lipinski, S.1
Till, A.2
Sina, C.3
Arlt, A.4
Grasberger, H.5
Schreiber, S.6
Rosenstiel, P.7
-
68
-
-
84876684569
-
A novel benzo[d]imidazole derivate prevents the development of dextran sulfate sodium-induced murine experimental colitis via inhibition of NLRP3 inflammasome
-
Liu W, Guo W, Wu J, Luo Q, Tao F, Gu Y, Shen Y, Li J, Tan R, Xu Q, Sun Y. A novel benzo[d]imidazole derivate prevents the development of dextran sulfate sodium-induced murine experimental colitis via inhibition of NLRP3 inflammasome. Biochem Pharmacol 85: 1504-1512, 2013.
-
(2013)
Biochem Pharmacol
, vol.85
, pp. 1504-1512
-
-
Liu, W.1
Guo, W.2
Wu, J.3
Luo, Q.4
Tao, F.5
Gu, Y.6
Shen, Y.7
Li, J.8
Tan, R.9
Xu, Q.10
Sun, Y.11
-
69
-
-
32944470765
-
Cryopyrin activates the inflammasome in response to toxins and ATP
-
Mariathasan S, Weiss DS, Newton K, McBride J, O’Rourke K, Roose-Girma M, Lee WP, Weinrauch Y, Monack DM, Dixit VM. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 440: 228-232, 2006.
-
(2006)
Nature
, vol.440
, pp. 228-232
-
-
Mariathasan, S.1
Weiss, D.S.2
Newton, K.3
McBride, J.4
O’rourke, K.5
Roose-Girma, M.6
Lee, W.P.7
Weinrauch, Y.8
Monack, D.M.9
Dixit, V.M.10
-
70
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F, Burns K, Tschopp J. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 10: 417-426, 2002.
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
71
-
-
37549066934
-
Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell death
-
McCall SH, Sahraei M, Young AB, Worley CS, Duncan JA, Ting JP, Marriott I. Osteoblasts express NLRP3, a nucleotide-binding domain and leucine-rich repeat region containing receptor implicated in bacterially induced cell death. J Bone Miner Res 23: 30-40, 2008.
-
(2008)
J Bone Miner Res
, vol.23
, pp. 30-40
-
-
McCall, S.H.1
Sahraei, M.2
Young, A.B.3
Worley, C.S.4
Duncan, J.A.5
Ting, J.P.6
Marriott, I.7
-
72
-
-
39749176359
-
Using Salmonella enterica serotype typhimurium to model intestinal fibrosis
-
McCormick BA. Using Salmonella enterica serotype typhimurium to model intestinal fibrosis. Gastroenterology 134: 872-875, 2008.
-
(2008)
Gastroenterology
, vol.134
, pp. 872-875
-
-
McCormick, B.A.1
-
73
-
-
28844448136
-
A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling
-
McDonald C, Chen FF, Ollendorff V, Ogura Y, Marchetto S, Lecine P, Borg JP, Nunez G. A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling. J Biol Chem 280: 40301-40309, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 40301-40309
-
-
McDonald, C.1
Chen, F.F.2
Ollendorff, V.3
Ogura, Y.4
Marchetto, S.5
Lecine, P.6
Borg, J.P.7
Nunez, G.8
-
74
-
-
19744366535
-
Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease
-
McGovern DP, Hysi P, Ahmad T, van Heel DA, Moffatt MF, Carey A, Cookson WO, Jewell DP. Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease. Hum Mol Genet 14: 1245-1250, 2005.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 1245-1250
-
-
McGovern, D.P.1
Hysi, P.2
Ahmad, T.3
Van Heel, D.A.4
Moffatt, M.F.5
Carey, A.6
Cookson, W.O.7
Jewell, D.P.8
-
75
-
-
33744493091
-
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
-
Miao EA, Alpuche-Aranda CM, Dors M, Clark AE, Bader MW, Miller SI, Aderem A. Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf. Nat Immunol 7: 569-575, 2006.
-
(2006)
Nat Immunol
, vol.7
, pp. 569-575
-
-
Miao, E.A.1
Alpuche-Aranda, C.M.2
Dors, M.3
Clark, A.E.4
Bader, M.W.5
Miller, S.I.6
Aderem, A.7
-
76
-
-
77649241461
-
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
-
Miao EA, Mao DP, Yudkovsky N, Bonneau R, Lorang CG, Warren SE, Leaf IA, Aderem A. Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome. Proc Natl Acad Sci USA 107: 3076-3080, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 3076-3080
-
-
Miao, E.A.1
Mao, D.P.2
Yudkovsky, N.3
Bonneau, R.4
Lorang, C.G.5
Warren, S.E.6
Leaf, I.A.7
Aderem, A.8
-
77
-
-
84863336565
-
Pathogen sensing by nucleotidebinding oligomerization domain-containing protein 2 (NOD2) is mediated by direct binding to muramyl dipeptide and ATP
-
Mo J, Boyle JP, Howard CB, Monie TP, Davis BK, Duncan JA. Pathogen sensing by nucleotidebinding oligomerization domain-containing protein 2 (NOD2) is mediated by direct binding to muramyl dipeptide and ATP. J Biol Chem 287: 23057-23067, 2012.
-
(2012)
J Biol Chem
, vol.287
, pp. 23057-23067
-
-
Mo, J.1
Boyle, J.P.2
Howard, C.B.3
Monie, T.P.4
Davis, B.K.5
Duncan, J.A.6
-
78
-
-
33645843633
-
Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection
-
Molofsky AB, Byrne BG, Whitfield NN, Madigan CA, Fuse ET, Tateda K, Swanson MS. Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection. J Exp Med 203: 1093-1104, 2006.
-
(2006)
J Exp Med
, vol.203
, pp. 1093-1104
-
-
Molofsky, A.B.1
Byrne, B.G.2
Whitfield, N.N.3
Madigan, C.A.4
Fuse, E.T.5
Tateda, K.6
Swanson, M.S.7
-
79
-
-
70349334298
-
A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome
-
Munoz-Planillo R, Franchi L, Miller LS, Nunez G. A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome. J Immunol 183: 3942-3948, 2009.
-
(2009)
J Immunol
, vol.183
, pp. 3942-3948
-
-
Munoz-Planillo, R.1
Franchi, L.2
Miller, L.S.3
Nunez, G.4
-
80
-
-
84899953763
-
Endosomes are specialized platforms for bacterial sensing and NOD2 signalling
-
Nakamura N, Lill JR, Phung Q, Jiang Z, Bakalarski C, de Maziere A, Klumperman J, Schlatter M, Delamarre L, Mellman I. Endosomes are specialized platforms for bacterial sensing and NOD2 signalling. Nature 509: 240-244, 2014.
-
(2014)
Nature
, vol.509
, pp. 240-244
-
-
Nakamura, N.1
Lill, J.R.2
Phung, Q.3
Jiang, Z.4
Bakalarski, C.5
De Maziere, A.6
Klumperman, J.7
Schlatter, M.8
Delamarre, L.9
Mellman, I.10
-
81
-
-
26044460479
-
NOD2 3020insC mutation and the pathogenesis of Crohn’s disease: Impaired IL-1beta production points to a loss-of-function phenotype
-
Netea MG, Ferwerda G, de Jong DJ, Girardin SE, Kullberg BJ, van der Meer JW. NOD2 3020insC mutation and the pathogenesis of Crohn’s disease: impaired IL-1beta production points to a loss-of-function phenotype. Neth J Med 63: 305-308, 2005.
-
(2005)
Neth J Med
, vol.63
, pp. 305-308
-
-
Netea, M.G.1
Ferwerda, G.2
De Jong, D.J.3
Girardin, S.E.4
Kullberg, B.J.5
Van Der Meer, J.W.6
-
82
-
-
27744559928
-
The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists
-
Netea MG, Ferwerda G, de Jong DJ, Werts C, Boneca IG, Jehanno M, Van Der Meer JW, Mengin-Lecreulx D, Sansonetti PJ, Philpott DJ, Dharancy S, Girardin SE. The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists. J Biol Chem 280: 35859-35867, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 35859-35867
-
-
Netea, M.G.1
Ferwerda, G.2
De Jong, D.J.3
Werts, C.4
Boneca, I.G.5
Jehanno, M.6
Van Der Meer, J.W.7
Mengin-Lecreulx, D.8
Sansonetti, P.J.9
Philpott, D.J.10
Dharancy, S.11
Girardin, S.E.12
-
83
-
-
84902588358
-
NLRC4 expression in intestinal epithelial cells mediates protection against an enteric pathogen
-
Nordlander S, Pott J, Maloy KJ. NLRC4 expression in intestinal epithelial cells mediates protection against an enteric pathogen. Mucosal Immunol 7: 775-785, 2013.
-
(2013)
Mucosal Immunol
, vol.7
, pp. 775-785
-
-
Nordlander, S.1
Pott, J.2
Maloy, K.J.3
-
84
-
-
79959369355
-
Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury
-
Normand S, Delanoye-Crespin A, Bressenot A, Huot L, Grandjean T, Peyrin-Biroulet L, Lemoine Y, Hot D, Chamaillard M. Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury. Proc Natl Acad Sci USA 108: 9601-9606, 2011.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 9601-9606
-
-
Normand, S.1
Delanoye-Crespin, A.2
Bressenot, A.3
Huot, L.4
Grandjean, T.5
Peyrin-Biroulet, L.6
Lemoine, Y.7
Hot, D.8
Chamaillard, M.9
-
85
-
-
0035895992
-
Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB
-
Ogura Y, Inohara N, Benito A, Chen FF, Yamaoka S, Nunez G. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB. J Biol Chem 276: 4812-4818, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 4812-4818
-
-
Ogura, Y.1
Inohara, N.2
Benito, A.3
Chen, F.F.4
Yamaoka, S.5
Nunez, G.6
-
86
-
-
10744222688
-
Expression of NOD2 in Paneth cells: A possible link to Crohn’s ileitis
-
Ogura Y, Lala S, Xin W, Smith E, Dowds TA, Chen FF, Zimmermann E, Tretiakova M, Cho JH, Hart J, Greenson JK, Keshav S, Nunez G. Expression of NOD2 in Paneth cells: a possible link to Crohn’s ileitis. Gut 52: 1591-1597, 2003.
-
(2003)
Gut
, vol.52
, pp. 1591-1597
-
-
Ogura, Y.1
Lala, S.2
Xin, W.3
Smith, E.4
Dowds, T.A.5
Chen, F.F.6
Zimmermann, E.7
Tretiakova, M.8
Cho, J.H.9
Hart, J.10
Greenson, J.K.11
Keshav, S.12
Nunez, G.13
-
87
-
-
29644434743
-
Listeria monocytogenes activated p38 MAPK and induced IL-8 secretion in a nucleotide-binding oligomerization domain 1-dependent manner in endothelial cells
-
Opitz B, Puschel A, Beermann W, Hocke AC, Forster S, Schmeck B, van Laak V, Chakraborty T, Suttorp N, Hippenstiel S. Listeria monocytogenes activated p38 MAPK and induced IL-8 secretion in a nucleotide-binding oligomerization domain 1-dependent manner in endothelial cells. J Immunol 176: 484-490, 2006.
-
(2006)
J Immunol
, vol.176
, pp. 484-490
-
-
Opitz, B.1
Puschel, A.2
Beermann, W.3
Hocke, A.C.4
Forster, S.5
Schmeck, B.6
Van Laak, V.7
Chakraborty, T.8
Suttorp, N.9
Hippenstiel, S.10
-
88
-
-
70349468054
-
Nod2 is required for the regulation of commensal microbiota in the intestine
-
Petnicki-Ocwieja T, Hrncir T, Liu YJ, Biswas A, Hudcovic T, Tlaskalova-Hogenova H, Kobayashi KS. Nod2 is required for the regulation of commensal microbiota in the intestine. Proc Natl Acad Sci USA 106: 15813-15818, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 15813-15818
-
-
Petnicki-Ocwieja, T.1
Hrncir, T.2
Liu, Y.J.3
Biswas, A.4
Hudcovic, T.5
Tlaskalova-Hogenova, H.6
Kobayashi, K.S.7
-
89
-
-
34548027736
-
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
-
Petrilli V, Papin S, Dostert C, Mayor A, Martinon F, Tschopp J. Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration. Cell Death Differ 14: 1583-1589, 2007.
-
(2007)
Cell Death Differ
, vol.14
, pp. 1583-1589
-
-
Petrilli, V.1
Papin, S.2
Dostert, C.3
Mayor, A.4
Martinon, F.5
Tschopp, J.6
-
90
-
-
84907597189
-
Bacterial sensor Nod2 prevents inflammation of the small intestine by restricting the expansion of the commensal Bacteroides vulgatus
-
Ramanan D, Tang MS, Bowcutt R, Loke P, Cadwell K. Bacterial sensor Nod2 prevents inflammation of the small intestine by restricting the expansion of the commensal Bacteroides vulgatus. Immunity 41: 311-324, 2014.
-
(2014)
Immunity
, vol.41
, pp. 311-324
-
-
Ramanan, D.1
Tang, M.S.2
Bowcutt, R.3
Loke, P.4
Cadwell, K.5
-
91
-
-
80052580369
-
Nod2 is essential for temporal development of intestinal microbial communities
-
Rehman A, Sina C, Gavrilova O, Hasler R, Ott S, Baines JF, Schreiber S, Rosenstiel P. Nod2 is essential for temporal development of intestinal microbial communities. Gut 60: 1354-1362, 2011.
-
(2011)
Gut
, vol.60
, pp. 1354-1362
-
-
Rehman, A.1
Sina, C.2
Gavrilova, O.3
Hasler, R.4
Ott, S.5
Baines, J.F.6
Schreiber, S.7
Rosenstiel, P.8
-
92
-
-
79957749035
-
The intestinal epithelial barrier in the control of homeostasis and immunity
-
Rescigno M. The intestinal epithelial barrier in the control of homeostasis and immunity. Trends Immunol 32: 256-264, 2011.
-
(2011)
Trends Immunol
, vol.32
, pp. 256-264
-
-
Rescigno, M.1
-
93
-
-
77953122347
-
Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn’s disease
-
Roberts RL, Topless RK, Phipps-Green AJ, Gearry RB, Barclay ML, Merriman TR. Evidence of interaction of CARD8 rs2043211 with NALP3 rs35829419 in Crohn’s disease. Genes Immun 11: 351-356, 2010.
-
(2010)
Genes Immun
, vol.11
, pp. 351-356
-
-
Roberts, R.L.1
Topless, R.K.2
Phipps-Green, A.J.3
Gearry, R.B.4
Barclay, M.L.5
Merriman, T.R.6
-
94
-
-
84877292277
-
Nod1 and Nod2 signaling does not alter the composition of intestinal bacterial communities at homeostasis
-
Robertson SJ, Zhou JY, Geddes K, Rubino SJ, Cho JH, Girardin SE, Philpott DJ. Nod1 and Nod2 signaling does not alter the composition of intestinal bacterial communities at homeostasis. Gut Microbes 4: 222-231, 2013.
-
(2013)
Gut Microbes
, vol.4
, pp. 222-231
-
-
Robertson, S.J.1
Zhou, J.Y.2
Geddes, K.3
Rubino, S.J.4
Cho, J.H.5
Girardin, S.E.6
Philpott, D.J.7
-
95
-
-
0037379915
-
TNFalpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells
-
Rosenstiel P, Fantini M, Brautigam K, Kuhbacher T, Waetzig GH, Seegert D, Schreiber S. TNFalpha and IFN-gamma regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells. Gastroenterology 124: 1001-1009, 2003.
-
(2003)
Gastroenterology
, vol.124
, pp. 1001-1009
-
-
Rosenstiel, P.1
Fantini, M.2
Brautigam, K.3
Kuhbacher, T.4
Waetzig, G.H.5
Seegert, D.6
Schreiber, S.7
-
96
-
-
84871797522
-
Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors
-
Rossol M, Pierer M, Raulien N, Quandt D, Meusch U, Rothe K, Schubert K, Schoneberg T, Schaefer M, Krugel U, Smajilovic S, Brauner-Osborne H, Baerwald C, Wagner U. Extracellular Ca2+ is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors. Nat Commun 3: 1329, 2012.
-
(2012)
Nat Commun
, vol.3
-
-
Rossol, M.1
Pierer, M.2
Raulien, N.3
Quandt, D.4
Meusch, U.5
Rothe, K.6
Schubert, K.7
Schoneberg, T.8
Schaefer, M.9
Krugel, U.10
Smajilovic, S.11
Brauner-Osborne, H.12
Baerwald, C.13
Wagner, U.14
-
97
-
-
66949174089
-
Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn’s disease in Swedish men
-
Schoultz I, Verma D, Halfvarsson J, Torkvist L, Fredrikson M, Sjoqvist U, Lordal M, Tysk C, Lerm M, Soderkvist P, Soderholm JD. Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn’s disease in Swedish men. Am J Gastroenterol 104: 1180-1188, 2009.
-
(2009)
Am J Gastroenterol
, vol.104
, pp. 1180-1188
-
-
Schoultz, I.1
Verma, D.2
Halfvarsson, J.3
Torkvist, L.4
Fredrikson, M.5
Sjoqvist, U.6
Lordal, M.7
Tysk, C.8
Lerm, M.9
Soderkvist, P.10
Soderholm, J.D.11
-
98
-
-
84908024529
-
Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa
-
Sellin ME, Muller AA, Felmy B, Dolowschiak T, Diard M, Tardivel A, Maslowski KM, Hardt WD. Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa. Cell Host Microbe 16: 237-248, 2014.
-
(2014)
Cell Host Microbe
, vol.16
, pp. 237-248
-
-
Sellin, M.E.1
Muller, A.A.2
Felmy, B.3
Dolowschiak, T.4
Diard, M.5
Tardivel, A.6
Maslowski, K.M.7
Hardt, W.D.8
-
99
-
-
84899949037
-
Mouse Paneth cell antimicrobial function is independent of Nod2
-
Shanahan MT, Carroll IM, Grossniklaus E, White A, von Furstenberg RJ, Barner R, Fodor AA, Henning SJ, Sartor RB, Gulati AS. Mouse Paneth cell antimicrobial function is independent of Nod2. Gut 63: 903-910, 2014.
-
(2014)
Gut
, vol.63
, pp. 903-910
-
-
Shanahan, M.T.1
Carroll, I.M.2
Grossniklaus, E.3
White, A.4
Von Furstenberg, R.J.5
Barner, R.6
Fodor, A.A.7
Henning, S.J.8
Sartor, R.B.9
Gulati, A.S.10
-
100
-
-
48549102504
-
NOD-like receptors (NLRs): Bona fide intracellular microbial sensors
-
Shaw MH, Reimer T, Kim YG, Nunez G. NOD-like receptors (NLRs): bona fide intracellular microbial sensors. Curr Opin Immunol 20: 377-382, 2008.
-
(2008)
Curr Opin Immunol
, vol.20
, pp. 377-382
-
-
Shaw, M.H.1
Reimer, T.2
Kim, Y.G.3
Nunez, G.4
-
101
-
-
84906571225
-
Inflammatory caspases are innate immune receptors for intracellular LPS
-
Shi J, Zhao Y, Wang Y, Gao W, Ding J, Li P, Hu L, Shao F. Inflammatory caspases are innate immune receptors for intracellular LPS. Nature 514: 187-192, 2014.
-
(2014)
Nature
, vol.514
, pp. 187-192
-
-
Shi, J.1
Zhao, Y.2
Wang, Y.3
Gao, W.4
Ding, J.5
Li, P.6
Hu, L.7
Shao, F.8
-
102
-
-
84902588650
-
Nlrp3 activation in the intestinal epithelium protects against a mucosal pathogen
-
Song-Zhao GX, Srinivasan N, Pott J, Baban D, Frankel G, Maloy KJ. Nlrp3 activation in the intestinal epithelium protects against a mucosal pathogen. Mucosal Immunol 7: 763-774, 2014.
-
(2014)
Mucosal Immunol
, vol.7
, pp. 763-774
-
-
Song-Zhao, G.X.1
Srinivasan, N.2
Pott, J.3
Baban, D.4
Frankel, G.5
Maloy, K.J.6
-
103
-
-
84875858095
-
The intermediate filament protein, vimentin, is a regulator of NOD2 activity
-
International Inflammatory Bowel Disease Genetics Consortium, Wilson DC, Satsangi J
-
Stevens C, Henderson P, Nimmo ER, Soares DC, Dogan B, Simpson KW, Barrett JC, International Inflammatory Bowel Disease Genetics Consortium, Wilson DC, Satsangi J. The intermediate filament protein, vimentin, is a regulator of NOD2 activity. Gut 62: 695-707, 2013.
-
(2013)
Gut
, vol.62
, pp. 695-707
-
-
Stevens, C.1
Henderson, P.2
Nimmo, E.R.3
Soares, D.C.4
Dogan, B.5
Simpson, K.W.6
Barrett, J.C.7
-
106
-
-
2342583513
-
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
-
Tanabe T, Chamaillard M, Ogura Y, Zhu L, Qiu S, Masumoto J, Ghosh P, Moran A, Predergast MM, Tromp G, Williams CJ, Inohara N, Nunez G. Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition. EMBO J 23: 1587-1597, 2004.
-
(2004)
EMBO J
, vol.23
, pp. 1587-1597
-
-
Tanabe, T.1
Chamaillard, M.2
Ogura, Y.3
Zhu, L.4
Qiu, S.5
Masumoto, J.6
Ghosh, P.7
Moran, A.8
Predergast, M.M.9
Tromp, G.10
Williams, C.J.11
Inohara, N.12
Nunez, G.13
-
107
-
-
73849121209
-
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
-
Travassos LH, Carneiro LA, Ramjeet M, Hussey S, Kim YG, Magalhaes JG, Yuan L, Soares F, Chea E, Le Bourhis L, Boneca IG, Allaoui A, Jones NL, Nunez G, Girardin SE, Philpott DJ. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol 11: 55-62, 2010.
-
(2010)
Nat Immunol
, vol.11
, pp. 55-62
-
-
Travassos, L.H.1
Carneiro, L.A.2
Ramjeet, M.3
Hussey, S.4
Kim, Y.G.5
Magalhaes, J.G.6
Yuan, L.7
Soares, F.8
Chea, E.9
Le Bourhis, L.10
Boneca, I.G.11
Allaoui, A.12
Jones, N.L.13
Nunez, G.14
Girardin, S.E.15
Philpott, D.J.16
-
108
-
-
84880651157
-
The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation
-
Triantafilou K, Hughes TR, Triantafilou M, Morgan BP. The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation. J Cell Sci 126: 2903-2913, 2013.
-
(2013)
J Cell Sci
, vol.126
, pp. 2903-2913
-
-
Triantafilou, K.1
Hughes, T.R.2
Triantafilou, M.3
Morgan, B.P.4
-
109
-
-
7644234401
-
HPepT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cells
-
Vavricka SR, Musch MW, Chang JE, Nakagawa Y, Phanvijhitsiri K, Waypa TS, Merlin D, Schneewind O, Chang EB. hPepT1 transports muramyl dipeptide, activating NF-kappaB and stimulating IL-8 secretion in human colonic Caco2/bbe cells. Gastroenterology 127: 1401-1409, 2004.
-
(2004)
Gastroenterology
, vol.127
, pp. 1401-1409
-
-
Vavricka, S.R.1
Musch, M.W.2
Chang, J.E.3
Nakagawa, Y.4
Phanvijhitsiri, K.5
Waypa, T.S.6
Merlin, D.7
Schneewind, O.8
Chang, E.B.9
-
110
-
-
9244245293
-
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island
-
Viala J, Chaput C, Boneca IG, Cardona A, Girardin SE, Moran AP, Athman R, Memet S, Huerre MR, Coyle AJ, DiStefano PS, Sansonetti PJ, Labigne A, Bertin J, Philpott DJ, Ferrero RL. Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nat Immunol 5: 1166-1174, 2004.
-
(2004)
Nat Immunol
, vol.5
, pp. 1166-1174
-
-
Viala, J.1
Chaput, C.2
Boneca, I.G.3
Cardona, A.4
Girardin, S.E.5
Moran, A.P.6
Athman, R.7
Memet, S.8
Huerre, M.R.9
Coyle, A.J.10
Distefano, P.S.11
Sansonetti, P.J.12
Labigne, A.13
Bertin, J.14
Philpott, D.J.15
Ferrero, R.L.16
-
111
-
-
58149159542
-
Common variants in the NLRP3 region contribute to Crohn’s disease susceptibility
-
Villani AC, Lemire M, Fortin G, Louis E, Silverberg MS, Collette C, Baba N, Libioulle C, Belaiche J, Bitton A, Gaudet D, Cohen A, Langelier D, Fortin PR, Wither JE, Sarfati M, Rutgeerts P, Rioux JD, Vermeire S, Hudson TJ, Franchimont D. Common variants in the NLRP3 region contribute to Crohn’s disease susceptibility. Nat Genet 41: 71-76, 2009.
-
(2009)
Nat Genet
, vol.41
, pp. 71-76
-
-
Villani, A.C.1
Lemire, M.2
Fortin, G.3
Louis, E.4
Silverberg, M.S.5
Collette, C.6
Baba, N.7
Libioulle, C.8
Belaiche, J.9
Bitton, A.10
Gaudet, D.11
Cohen, A.12
Langelier, D.13
Fortin, P.R.14
Wither, J.E.15
Sarfati, M.16
Rutgeerts, P.17
Rioux, J.D.18
Vermeire, S.19
Hudson, T.J.20
Franchimont, D.21
more..
-
112
-
-
84864317101
-
The NLRP12 inflammasome recognizes Yersinia pestis
-
Vladimer GI, Weng D, Paquette SW, Vanaja SK, Rathinam VA, Aune MH, Conlon JE, Burbage JJ, Proulx MK, Liu Q, Reed G, Mecsas JC, Iwakura Y, Bertin J, Goguen JD, Fitzgerald KA, Lien E. The NLRP12 inflammasome recognizes Yersinia pestis. Immunity 37: 96-107, 2012.
-
(2012)
Immunity
, vol.37
, pp. 96-107
-
-
Vladimer, G.I.1
Weng, D.2
Paquette, S.W.3
Vanaja, S.K.4
Rathinam, V.A.5
Aune, M.H.6
Conlon, J.E.7
Burbage, J.J.8
Proulx, M.K.9
Liu, Q.10
Reed, G.11
Mecsas, J.C.12
Iwakura, Y.13
Bertin, J.14
Goguen, J.D.15
Fitzgerald, K.A.16
Lien, E.17
-
113
-
-
0010464874
-
PYPAF7, a novel PYRINcontaining Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing
-
Wang L, Manji GA, Grenier JM, Al-Garawi A, Merriam S, Lora JM, Geddes BJ, Briskin M, DiStefano PS, Bertin J. PYPAF7, a novel PYRINcontaining Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing. J Biol Chem 277: 29874-29880, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 29874-29880
-
-
Wang, L.1
Manji, G.A.2
Grenier, J.M.3
Al-Garawi, A.4
Merriam, S.5
Lora, J.M.6
Geddes, B.J.7
Briskin, M.8
Distefano, P.S.9
Bertin, J.10
-
114
-
-
84896691062
-
NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion
-
Wlodarska M, Thaiss CA, Nowarski R, Henao- Mejia J, Zhang JP, Brown EM, Frankel G, Levy M, Katz MN, Philbrick WM, Elinav E, Finlay BB, Flavell RA. NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion. Cell 156: 1045-1059, 2014.
-
(2014)
Cell
, vol.156
, pp. 1045-1059
-
-
Wlodarska, M.1
Thaiss, C.A.2
Nowarski, R.3
Henao- Mejia, J.4
Zhang, J.P.5
Brown, E.M.6
Frankel, G.7
Levy, M.8
Katz, M.N.9
Philbrick, W.M.10
Elinav, E.11
Finlay, B.B.12
Flavell, R.A.13
-
115
-
-
77950002937
-
The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis
-
Zaki MH, Boyd KL, Vogel P, Kastan MB, Lamkanfi M, Kanneganti TD. The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity 32: 379-391, 2010.
-
(2010)
Immunity
, vol.32
, pp. 379-391
-
-
Zaki, M.H.1
Boyd, K.L.2
Vogel, P.3
Kastan, M.B.4
Lamkanfi, M.5
Kanneganti, T.D.6
-
116
-
-
84891906749
-
Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection
-
Zaki MH, Man SM, Vogel P, Lamkanfi M, Kanneganti TD. Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection. Proc Natl Acad Sci USA 111: 385-390, 2014.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 385-390
-
-
Zaki, M.H.1
Man, S.M.2
Vogel, P.3
Lamkanfi, M.4
Kanneganti, T.D.5
-
117
-
-
81255189478
-
The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis
-
Zaki MH, Vogel P, Malireddi RK, Body-Malapel M, Anand PK, Bertin J, Green DR, Lamkanfi M, Kanneganti TD. The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis. Cancer Cell 20: 649-660, 2011.
-
(2011)
Cancer Cell
, vol.20
, pp. 649-660
-
-
Zaki, M.H.1
Vogel, P.2
Malireddi, R.K.3
Body-Malapel, M.4
Anand, P.K.5
Bertin, J.6
Green, D.R.7
Lamkanfi, M.8
Kanneganti, T.D.9
-
118
-
-
84858702357
-
Control of NOD2 and Rip2-dependent innate immune activation by GEF-H1
-
Zhao Y, Alonso C, Ballester I, Song JH, Chang SY, Guleng B, Arihiro S, Murray PJ, Xavier R, Kobayashi KS, Reinecker HC. Control of NOD2 and Rip2-dependent innate immune activation by GEF-H1. Inflamm Bowel Dis 18: 603-612, 2012.
-
(2012)
Inflamm Bowel Dis
, vol.18
, pp. 603-612
-
-
Zhao, Y.1
Alonso, C.2
Ballester, I.3
Song, J.H.4
Chang, S.Y.5
Guleng, B.6
Arihiro, S.7
Murray, P.J.8
Xavier, R.9
Kobayashi, K.S.10
Reinecker, H.C.11
-
119
-
-
80053349020
-
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
-
Zhao Y, Yang J, Shi J, Gong YN, Lu Q, Xu H, Liu L, Shao F. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature 477: 596-600, 2011.
-
(2011)
Nature
, vol.477
, pp. 596-600
-
-
Zhao, Y.1
Yang, J.2
Shi, J.3
Gong, Y.N.4
Lu, Q.5
Xu, H.6
Liu, L.7
Shao, F.8
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