The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists

Journal of Biological Chemistry

Volumn 280, Issue 43, 2005, Pages 35859-35867

  Netea, Mihai G ^a   Ferwerda, Gerben ^a   De Jong, Dirk J ^a   Werts, Catherine ^d   Boneca, Ivo G ^d   Jéhanno, Muguette ^d   Van Der Meer, Jos W M ^a   Mengin Lecreulx, Dominique ^b   Sansonetti, Philippe J ^d   Philpott, Dana J ^d   Dharancy, Sébastien ^c   Girardin, Stephen E ^d  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b INSTITUTE FOR INTEGRATIVE BIOLOGY OF THE CELL I2BC   (France)

^c INSERM   (France)

^d INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BACTERIA; BACTERIOLOGY; DISEASES; GENES; POLYSACCHARIDES; PROTEINS;

CROHN DISEASE; LIPOPOLYSACCHARIDES; MUTATION; PEPTIDOGLYCAN;

MUTAGENESIS;

ARGININE; CASPASE RECRUITMENT DOMAIN PROTEIN 15; DIAMINOPIMELIC ACID; LIPOPOLYSACCHARIDE; LIPOTEICHOIC ACID; MURAMYL DIPEPTIDE; N ACETYLMURAMYLALANYL DEXTRO GLUTAMINYLDIAMINOPIMELIC ACID; PEPTIDOGLYCAN; PROTEIN NOD1; PROTEIN S; SCAVENGER; TOLL LIKE RECEPTOR; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CROHN DISEASE; FRAMESHIFT MUTATION; GENETIC PREDISPOSITION; GRAM NEGATIVE BACTERIUM; HOMOZYGOSITY; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID MOTIFS; ANIMALS; CELL LINE; CROHN DISEASE; DOWN-REGULATION; FRAMESHIFT MUTATION; GENOTYPE; HOMOZYGOTE; HUMANS; HYDROLYSIS; INTERLEUKIN-10; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED C57BL; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MUTATION; NF-KAPPA B; NOD1 SIGNALING ADAPTOR PROTEIN; NOD2 SIGNALING ADAPTOR PROTEIN; PEPTIDES; PEPTIDOGLYCAN; PLASMIDS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TEICHOIC ACIDS; TOLL-LIKE RECEPTORS; TRANSFECTION;

ANIMALIA; BACTERIA (MICROORGANISMS); NEGIBACTERIA;

EID: 27744559928     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M504924200     Document Type: Article

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