메뉴 건너뛰기




Volumn 18, Issue 4, 2012, Pages 603-612

Control of NOD2 and Rip2-Dependent Innate Immune Activation by GEF-H1

Author keywords

Crohn's disease; Innate immune regulation; NOD like receptors; Src kinase; Tyrosine phosphorylation

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CYTOKINE; GUANINE NUCLEOTIDE EXCHANGE FACTOR H1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN; RIP2 PROTEIN; UNCLASSIFIED DRUG;

EID: 84858702357     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.21851     Document Type: Article
Times cited : (36)

References (43)
  • 1
    • 38549158099 scopus 로고    scopus 로고
    • Phagocytosis and comparative innate immunity: Learning on the fly
    • DOI 10.1038/nri2240, PII NRI2240
    • Stuart LM, Ezekowitz RA. Phagocytosis and comparative innate immunity: learning on the fly. Nat Rev Immunol. 2008;8:131-141. (Pubitemid 351161303)
    • (2008) Nature Reviews Immunology , vol.8 , Issue.2 , pp. 131-141
    • Stuart, L.M.1    Ezekowitz, R.A.2
  • 2
    • 0033593337 scopus 로고    scopus 로고
    • The Dbl-related protein, Lfc, localizes to microtubules and mediates the activation of Rac signaling pathways in cells
    • Glaven JA, Whitehead I, Bagrodia S, et al. The Dbl-related protein, Lfc, localizes to microtubules and mediates the activation of Rac signaling pathways in cells. J Biol Chem. 1999;274:2279-2285.
    • (1999) J Biol Chem , vol.274 , pp. 2279-2285
    • Glaven, J.A.1    Whitehead, I.2    Bagrodia, S.3
  • 3
    • 0036228955 scopus 로고    scopus 로고
    • Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton
    • DOI 10.1038/ncb773
    • Krendel M, Zenke FT, Bokoch GM. Nucleotide exchange factor GEFH1 mediates cross-talk between microtubules and the actin cytoskeleton. Nat Cell Biol. 2002;4:294-301. (Pubitemid 34308855)
    • (2002) Nature Cell Biology , vol.4 , Issue.4 , pp. 294-301
    • Krendel, M.1    Zenke, F.T.2    Bokoch, G.M.3
  • 4
    • 57149093623 scopus 로고    scopus 로고
    • GEF-H1 mediated control of NOD1 dependent NF-kappaB activation by Shigella effectors
    • Fukazawa A, Alonso C, Kurachi K, et al. GEF-H1 mediated control of NOD1 dependent NF-kappaB activation by Shigella effectors. PLoS Pathog. 2008;4:e1000228.
    • (2008) PLoS Pathog , vol.4
    • Fukazawa, A.1    Alonso, C.2    Kurachi, K.3
  • 5
    • 17644366913 scopus 로고    scopus 로고
    • NOD-LRR proteins: Role in host-microbial interactions and inflammatory disease
    • Inohara, Chamaillard, McDonald C, et al. NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. Annu Rev Biochem. 2005;74:355-383.
    • (2005) Annu Rev Biochem , vol.74 , pp. 355-383
    • Inohara1    Chamaillard2    McDonald, C.3
  • 8
    • 77952706524 scopus 로고    scopus 로고
    • Cooperation between multiple microbial pattern recognition systems is important for host protection against the intracellular pathogen Legionella pneumophila
    • Archer KA, Ader F, Kobayashi KS, et al. Cooperation between multiple microbial pattern recognition systems is important for host protection against the intracellular pathogen Legionella pneumophila. Infect Immun. 2010;78:2477-2487.
    • (2010) Infect Immun , vol.78 , pp. 2477-2487
    • Archer, K.A.1    Ader, F.2    Kobayashi, K.S.3
  • 9
    • 66349097787 scopus 로고    scopus 로고
    • The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection
    • Shimada K, Chen S, Dempsey PW, et al. The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection. PLoS Pathog. 2009;5:e1000379.
    • (2009) PLoS Pathog , vol.5
    • Shimada, K.1    Chen, S.2    Dempsey, P.W.3
  • 10
    • 78649824846 scopus 로고    scopus 로고
    • Innate signals from Nod2 block respiratory tolerance and program T(H)2-driven allergic inflammation
    • Duan W, Mehta AK, Magalhaes JG, et al. Innate signals from Nod2 block respiratory tolerance and program T(H)2-driven allergic inflammation. J Allergy Clin Immunol. 2010;126:1284-1293.
    • (2010) J Allergy Clin Immunol , vol.126 , pp. 1284-1293
    • Duan, W.1    Mehta, A.K.2    Magalhaes, J.G.3
  • 11
    • 77957047689 scopus 로고    scopus 로고
    • Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum
    • Biswas A, Liu YJ, Hao L, et al. Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum. Proc Natl Acad Sci U S A. 2010;107:14739-14744.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 14739-14744
    • Biswas, A.1    Liu, Y.J.2    Hao, L.3
  • 12
    • 37548999003 scopus 로고    scopus 로고
    • NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2
    • Yang Y, Yin C, Pandey A, et al. NOD2 pathway activation by MDP or Mycobacterium tuberculosis infection involves the stable polyubiquitination of Rip2. J Biol Chem. 2007;282:36223-36229.
    • (2007) J Biol Chem , vol.282 , pp. 36223-36229
    • Yang, Y.1    Yin, C.2    Pandey, A.3
  • 18
    • 4444253690 scopus 로고    scopus 로고
    • NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
    • DOI 10.1038/ni1092
    • Watanabe T, Kitani A, Murray PJ, et al. NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat Immunol. 2004;5:800-808. (Pubitemid 39172973)
    • (2004) Nature Immunology , vol.5 , Issue.8 , pp. 800-808
    • Watanabe, T.1    Kitani, A.2    Murray, P.J.3    Strober, W.4
  • 22
    • 0032524908 scopus 로고    scopus 로고
    • RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis
    • DOI 10.1074/jbc.273.20.12296
    • Inohara N, del Peso L, Koseki T, et al. RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis. J Biol Chem. 1998;273:12296-12300. (Pubitemid 28240597)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.20 , pp. 12296-12300
    • Inohara, N.1    Del, P.L.2    Koseki, T.3    Chen, S.4    Nunez, G.5
  • 24
    • 14744299357 scopus 로고    scopus 로고
    • The RIP kinases: Crucial integrators of cellular stress
    • DOI 10.1016/j.tibs.2005.01.003
    • Meylan E, Tschopp J. The RIP kinases: crucial integrators of cellular stress. Trends Biochem Sci. 2005;30:151-159. (Pubitemid 40332531)
    • (2005) Trends in Biochemical Sciences , vol.30 , Issue.3 , pp. 151-159
    • Meylan, E.1    Tschopp, J.2
  • 25
    • 0032479145 scopus 로고    scopus 로고
    • RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase
    • DOI 10.1074/jbc.273.27.16968
    • McCarthy JV, Ni J, Dixit VM. RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase. J Biol Chem. 1998;273:16968-16975. (Pubitemid 28311729)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.27 , pp. 16968-16975
    • McCarthy, J.V.1    Ni, J.2    Dixit, V.M.3
  • 27
    • 70549086229 scopus 로고    scopus 로고
    • Large-scale proteomics analysis of the human kinome
    • Oppermann FS, Gnad F, Olsen JV, et al. Large-scale proteomics analysis of the human kinome. Mol Cell Proteomics. 2009;8:1751-1764.
    • (2009) Mol Cell Proteomics , vol.8 , pp. 1751-1764
    • Oppermann, F.S.1    Gnad, F.2    Olsen, J.V.3
  • 28
    • 0038385023 scopus 로고    scopus 로고
    • i proteins and Src tyrosine kinase in TNFalpha production induced by lipopolysaccharide, group B Streptococci and Staphylococcus aureus
    • DOI 10.1016/S1043-4666(03)00122-4
    • Fan H, Teti G, Ashton S, et al. Involvement of G(i) proteins and Src tyrosine kinase in TNFalpha production induced by lipopolysaccharide, group B Streptococci and Staphylococcus aureus. Cytokine. 2003;22:126-133. (Pubitemid 36808758)
    • (2003) Cytokine , vol.22 , Issue.5 , pp. 126-133
    • Fan, H.1    Teti, G.2    Ashton, S.3    Guyton, K.4    Tempel, G.E.5    Halushka, P.V.6    Cook, J.A.7
  • 29
    • 0033228567 scopus 로고    scopus 로고
    • The src family-selective tyrosine kinase inhibitor PP1 blocks LPS and IFN-gamma-mediated TNF and iNOS production in murine macrophages
    • Orlicek SL, Hanke JH, English BK. The src family-selective tyrosine kinase inhibitor PP1 blocks LPS and IFN-gamma-mediated TNF and iNOS production in murine macrophages. Shock. 1999;12:350-354.
    • (1999) Shock , vol.12 , pp. 350-354
    • Orlicek, S.L.1    Hanke, J.H.2    English, B.K.3
  • 30
    • 35548985405 scopus 로고    scopus 로고
    • Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages
    • DOI 10.1016/j.molimm.2007.07.026, PII S0161589007006578
    • Smolinska MJ, Horwood NJ, Page TH, et al. Chemical inhibition of Src family kinases affects major LPS-activated pathways in primary human macrophages. Mol Immunol. 2008;45:990-1000. (Pubitemid 350017845)
    • (2008) Molecular Immunology , vol.45 , Issue.4 , pp. 990-1000
    • Smolinska, M.J.1    Horwood, N.J.2    Page, T.H.3    Smallie, T.4    Foxwell, B.M.J.5
  • 31
    • 78649890151 scopus 로고    scopus 로고
    • Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses
    • Tigno-Aranjuez JT, Asara JM, Abbott DW. Inhibition of RIP2's tyrosine kinase activity limits NOD2-driven cytokine responses. Genes Dev. 2010;24:2666-2677.
    • (2010) Genes Dev , vol.24 , pp. 2666-2677
    • Tigno-Aranjuez, J.T.1    Asara, J.M.2    Abbott, D.W.3
  • 33
    • 70349485216 scopus 로고    scopus 로고
    • Activation of NOD2- Mediated intestinal pathway in a pediatric population with Crohn's disease
    • Negroni A, Stronati L, Pierdomenico M, et al. Activation of NOD2- mediated intestinal pathway in a pediatric population with Crohn's disease. Inflamm Bowel Dis. 2009;15:1145-1154.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 1145-1154
    • Negroni, A.1    Stronati, L.2    Pierdomenico, M.3
  • 34
    • 34547176642 scopus 로고    scopus 로고
    • Unravelling the pathogenesis of inflammatory bowel disease
    • DOI 10.1038/nature06005, PII NATURE06005
    • Xavier RJ, Podolsky DK. Unravelling the pathogenesis of inflammatory bowel disease. Nature. 2007;448:427-434. (Pubitemid 47123518)
    • (2007) Nature , vol.448 , Issue.7152 , pp. 427-434
    • Xavier, R.J.1    Podolsky, D.K.2
  • 35
    • 0037075549 scopus 로고    scopus 로고
    • Involvement of receptor-interacting protein 2 in innate and adaptive immune responses
    • DOI 10.1038/416190a
    • Chin AI, Dempsey PW, Bruhn K, et al. Involvement of receptor-interacting protein 2 in innate and adaptive immune responses. Nature. 2002;416:190-194. (Pubitemid 34246478)
    • (2002) Nature , vol.416 , Issue.6877 , pp. 190-194
    • Chin, A.I.1    Dempsey, P.W.2    Bruhn, K.3    Miller, J.F.4    Xu, Y.5    Cheng, G.6
  • 39
    • 62749113471 scopus 로고    scopus 로고
    • Tyrosine kinases and inflammatory signalling
    • Page TH, Smolinska M, Gillespie J, et al. Tyrosine kinases and inflammatory signalling. Curr Mol Med. 2009;9:69-85.
    • (2009) Curr Mol Med , vol.9 , pp. 69-85
    • Page, T.H.1    Smolinska, M.2    Gillespie, J.3
  • 41
    • 36549040859 scopus 로고    scopus 로고
    • The selectivity of protein kinase inhibitors: A further update
    • Bain J, Plater L, Elliott M, et al. The selectivity of protein kinase inhibitors: a further update. Biochem J. 2007;408:297-315.
    • (2007) Biochem J , vol.408 , pp. 297-315
    • Bain, J.1    Plater, L.2    Elliott, M.3
  • 42
    • 49649101158 scopus 로고    scopus 로고
    • Synthesis and characterization of novel quinazoline type inhibitors for mutant and wild-type EGFR and RICK kinases
    • Breza N, Pato J, Orfi L, et al. Synthesis and characterization of novel quinazoline type inhibitors for mutant and wild-type EGFR and RICK kinases. J Recept Signal Transduct Res. 2008;28:361-373.
    • (2008) J Recept Signal Transduct Res , vol.28 , pp. 361-373
    • Breza, N.1    Pato, J.2    Orfi, L.3
  • 43
    • 19944432043 scopus 로고    scopus 로고
    • Cellular targets of gefitinib
    • Brehmer D, Greff Z, Godl K, et al. Cellular targets of gefitinib. Cancer Res. 2005;65:379-382.
    • (2005) Cancer Res , vol.65 , pp. 379-382
    • Brehmer, D.1    Greff, Z.2    Godl, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.