-
1
-
-
80051997952
-
Dynamic interactions between transposable elements and their hosts
-
Levin HL, Moran JV. Dynamic interactions between transposable elements and their hosts. Nat Rev Genet 2011;12(9):615-27
-
(2011)
Nat Rev Genet
, vol.12
, Issue.9
, pp. 615-627
-
-
Levin, H.L.1
Moran, J.V.2
-
2
-
-
0037372003
-
Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
-
Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet 2003;33(Suppl):245-54
-
(2003)
Nat Genet
, vol.33
, pp. 245-254
-
-
Jaenisch, R.1
Bird, A.2
-
3
-
-
84904563107
-
The role of genomic imprinting in biology and disease: An expanding view
-
Peters J. The role of genomic imprinting in biology and disease: an expanding view. Nat Rev Genet 2014;15(8):517-30
-
(2014)
Nat Rev Genet
, vol.15
, Issue.8
, pp. 517-530
-
-
Peters, J.1
-
4
-
-
84874194072
-
DNA methylation: Roles in mammalian development
-
Smith ZD, Meissner A. DNA methylation: roles in mammalian development. Nat Rev Genet 2013;14(3):204-20
-
(2013)
Nat Rev Genet
, vol.14
, Issue.3
, pp. 204-220
-
-
Smith, Z.D.1
Meissner, A.2
-
5
-
-
70450217879
-
Human DNA methylomes at base resolution show widespread epigenomic differences
-
Lister R, Pelizzola M, Dowen RH, et al. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature 2009;462(7271):315-22 .. This study was the first whole-genome DNA methylation mapping of a human genome and describes the presence of non-cytosine-guanine (CpG) dinucleotide methylation.
-
(2009)
Nature
, vol.462
, Issue.7271
, pp. 315-322
-
-
Lister, R.1
Pelizzola, M.2
Dowen, R.H.3
-
6
-
-
84883719710
-
Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods
-
Stevens M, Cheng JB, Li D, et al. Estimating absolute methylation levels at single-CpG resolution from methylation enrichment and restriction enzyme sequencing methods. Genome Res 2013; 23(9):1541-53
-
(2013)
Genome Res
, vol.23
, Issue.9
, pp. 1541-1553
-
-
Stevens, M.1
Cheng, J.B.2
Li, D.3
-
7
-
-
45449108787
-
Genome-scale relationships between cytosine methylation and dinucleotide abundances in animals
-
Simmen MW. Genome-scale relationships between cytosine methylation and dinucleotide abundances in animals. Genomics 2008;92(1):33-40
-
(2008)
Genomics
, vol.92
, Issue.1
, pp. 33-40
-
-
Simmen, M.W.1
-
8
-
-
84876946045
-
Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics
-
Shen L, Wu H, Diep D, et al. Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics. Cell 2013;153(3):692-706 . This article summarizes the newly identified functional modifications of cytosine bases in the mammalian genome.
-
(2013)
Cell
, vol.153
, Issue.3
, pp. 692-706
-
-
Shen, L.1
Wu, H.2
Diep, D.3
-
9
-
-
0025975985
-
DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein
-
Boyes J, Bird A. DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein. Cell 1991;64(6):1123-34
-
(1991)
Cell
, vol.64
, Issue.6
, pp. 1123-1134
-
-
Boyes, J.1
Bird, A.2
-
10
-
-
0023216891
-
CpG islands in vertebrate genomes
-
Gardiner-Garden M, Frommer M. CpG islands in vertebrate genomes. J Mol Biol 1987;196(2):261-82
-
(1987)
J Mol Biol
, vol.196
, Issue.2
, pp. 261-282
-
-
Gardiner-Garden, M.1
Frommer, M.2
-
12
-
-
77958580776
-
DNA methylation and memory formation
-
Day JJ, Sweatt JD. DNA methylation and memory formation. Nat Neurosci 2010; 13(11):1319-23
-
(2010)
Nat Neurosci
, vol.13
, Issue.11
, pp. 1319-1323
-
-
Day, J.J.1
Sweatt, J.D.2
-
13
-
-
84901029300
-
X chromosome regulation: Diverse patterns in development tissues and disease
-
Deng X, Berletch JB, Nguyen DK, Disteche CM. X chromosome regulation: diverse patterns in development, tissues and disease. Nat Rev Genet 2014;15(6):367-78
-
(2014)
Nat Rev Genet
, vol.15
, Issue.6
, pp. 367-378
-
-
Deng, X.1
Berletch, J.B.2
Nguyen, D.K.3
Disteche, C.M.4
-
14
-
-
79958754527
-
Validation of a DNA methylation microarray for 450 000 CpG sites in the human genome
-
Sandoval J, Heyn H, Moran S, et al. Validation of a DNA methylation microarray for 450, 000 CpG sites in the human genome. Epigenetics 2011;6(6): 692-702 . This article presents a comprehensive analysis of the more than 450, 000 genomic regions covered by the Human Methylation 450K BeadChip and introduces the denomination of open sea for CpG sites located more than 4 kb away from a CpG island.
-
(2011)
Epigenetics
, vol.6
, Issue.6
, pp. 692-702
-
-
Sandoval, J.1
Heyn, H.2
Moran, S.3
-
15
-
-
59149084538
-
The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
-
Irizarry RA, Ladd-Acosta C, Wen B, et al. The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet 2009;41(2):178-86 .. This study identified tissue- and cancer-specific differentially methylated regions located outside the traditional CpG islands, in regions denominated CpG shores.
-
(2009)
Nat Genet
, vol.41
, Issue.2
, pp. 178-186
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Wen, B.3
-
16
-
-
70649095120
-
Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts
-
Doi A, Park IH, Wen B, et al. Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nat Genet 2009; 41(12):1350-3
-
(2009)
Nat Genet
, vol.41
, Issue.12
, pp. 1350-1353
-
-
Doi, A.1
Park, I.H.2
Wen, B.3
-
17
-
-
84872016931
-
Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium Human Methylation 450 BeadChips
-
Shen J, Wang S, Zhang YJ, et al. Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium Human Methylation 450 BeadChips. Epigenetics 2013;8(1): 34-43
-
(2013)
Epigenetics
, vol.8
, Issue.1
, pp. 34-43
-
-
Shen, J.1
Wang, S.2
Zhang, Y.J.3
-
18
-
-
84887365803
-
Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis
-
Marzese DM, Scolyer RA, Huynh JL, et al. Epigenome-wide DNA methylation landscape of melanoma progression to brain metastasis reveals aberrations on homeobox D cluster associated with prognosis. Hum Mol Genet 2014;23(1):226-38
-
(2014)
Hum Mol Genet
, vol.23
, Issue.1
, pp. 226-238
-
-
Marzese, D.M.1
Scolyer, R.A.2
Huynh, J.L.3
-
19
-
-
84863986133
-
Functions of DNA methylation: Islands, start sites, gene bodies and beyond
-
Jones PA. Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat Rev Genet 2012;13(7):484-92 .. This article reviews the function of DNA methylation with regard to the CpG density and gene structure.
-
(2012)
Nat Rev Genet
, vol.13
, Issue.7
, pp. 484-492
-
-
Jones, P.A.1
-
20
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
Herman JG, Baylin SB. Gene silencing in cancer in association with promoter hypermethylation. N Engl J Med 2003; 349(21):2042-54
-
(2003)
N Engl J Med
, vol.349
, Issue.21
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
21
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
Weber M, Hellmann I, Stadler MB, et al. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 2007;39(4):457-66 . This study classified gene promoters according to their CpG density and functionality.
-
(2007)
Nat Genet
, vol.39
, Issue.4
, pp. 457-466
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
-
22
-
-
84899851308
-
Fine-tuning of epigenetic regulation with respect to promoter CpG content in a cell type-specific manner
-
Li R, Mav D, Grimm SA, et al. Fine-tuning of epigenetic regulation with respect to promoter CpG content in a cell type-specific manner. Epigenetics 2014;9(5): 747-59
-
(2014)
Epigenetics
, vol.9
, Issue.5
, pp. 747-759
-
-
Li, R.1
Mav, D.2
Grimm, S.A.3
-
23
-
-
7544231794
-
Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells
-
Lorincz MC, Dickerson DR, Schmitt M, Groudine M. Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells. Nat Struct Mol Biol 2004;11(11):1068-75
-
(2004)
Nat Struct Mol Biol
, vol.11
, Issue.11
, pp. 1068-1075
-
-
Lorincz, M.C.1
Dickerson, D.R.2
Schmitt, M.3
Groudine, M.4
-
24
-
-
36748998985
-
Identification of DNA methylation in 3' genomic regions that are associated with upregulation of gene expression in colorectal cancer
-
Smith JF, Mahmood S, Song F, et al. Identification of DNA methylation in 3' genomic regions that are associated with upregulation of gene expression in colorectal cancer. Epigenetics 2007;2(3):161-72
-
(2007)
Epigenetics
, vol.2
, Issue.3
, pp. 161-172
-
-
Smith, J.F.1
Mahmood, S.2
Song, F.3
-
25
-
-
79959209733
-
5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells
-
Stroud H, Feng S, Morey Kinney S, et al. 5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells. Genome Biol 2011; 12(6):R54
-
(2011)
Genome Biol
, vol.12
, Issue.6
, pp. R54
-
-
Stroud, H.1
Feng, S.2
Morey Kinney, S.3
-
26
-
-
67650090496
-
Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity
-
Schmidl C, Klug M, Boeld TJ, et al. Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity. Genome Res 2009;19(7): 1165-74 . This study identified a key role of DNA methylation at enhancer regions in determining cellular fate.
-
(2009)
Genome Res
, vol.19
, Issue.7
, pp. 1165-1174
-
-
Schmidl, C.1
Klug, M.2
Boeld, T.J.3
-
27
-
-
84891766375
-
Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sites
-
Kozlenkov A, Roussos P, Timashpolsky A, et al. Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sites. Nucleic Acids Res 2014;42(1):109-27
-
(2014)
Nucleic Acids Res
, vol.42
, Issue.1
, pp. 109-127
-
-
Kozlenkov, A.1
Roussos, P.2
Timashpolsky, A.3
-
28
-
-
0027251502
-
Proposed roles for DNA methylation in Alu transcriptional repression and mutational inactivation
-
Liu WM, Schmid CW. Proposed roles for DNA methylation in Alu transcriptional repression and mutational inactivation. Nucleic Acids Res 1993;21(6):1351-9
-
(1993)
Nucleic Acids Res
, vol.21
, Issue.6
, pp. 1351-1359
-
-
Liu, W.M.1
Schmid, C.W.2
-
30
-
-
33947315736
-
Cancer epigenomics: DNA methylomes and histone-modification maps
-
Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet 2007;8(4):286-98
-
(2007)
Nat Rev Genet
, vol.8
, Issue.4
, pp. 286-298
-
-
Esteller, M.1
-
31
-
-
40849139208
-
Epigenetics in cancer
-
Esteller M. Epigenetics in cancer. N Engl J Med 2008;358(11):1148-59 .. This article reviews the DNA methylation misbalanced in cancer cells.
-
(2008)
N Engl J Med
, vol.358
, Issue.11
, pp. 1148-1159
-
-
Esteller, M.1
-
32
-
-
80053144962
-
A decade of exploring the cancer epigenome - Biological and translational implications
-
Baylin SB, Jones PA. A decade of exploring the cancer epigenome - biological and translational implications. Nat Rev Cancer 2011;11(10):726-34
-
(2011)
Nat Rev Cancer
, vol.11
, Issue.10
, pp. 726-734
-
-
Baylin, S.B.1
Jones, P.A.2
-
33
-
-
29244469466
-
The epigenetic progenitor origin of human cancer
-
Feinberg AP, Ohlsson R, Henikoff S. The epigenetic progenitor origin of human cancer. Nat Rev Genet 2006;7(1):21-33
-
(2006)
Nat Rev Genet
, vol.7
, Issue.1
, pp. 21-33
-
-
Feinberg, A.P.1
Ohlsson, R.2
Henikoff, S.3
-
34
-
-
18244388241
-
DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis
-
Esteller M, Fraga MF, Guo M, et al. DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis. Hum Mol Genet 2001; 10(26):3001-7
-
(2001)
Hum Mol Genet
, vol.10
, Issue.26
, pp. 3001-3007
-
-
Esteller, M.1
Fraga, M.F.2
Guo, M.3
-
35
-
-
0343621494
-
Aberrant CpG-island methylation has non-random and tumour-type-specific patterns
-
Costello JF, Fruhwald MC, Smiraglia DJ, et al. Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet 2000;24(2):132-8
-
(2000)
Nat Genet
, vol.24
, Issue.2
, pp. 132-138
-
-
Costello, J.F.1
Fruhwald, M.C.2
Smiraglia, D.J.3
-
36
-
-
84907997839
-
Gene body methylation can alter gene expression and is a therapeutic target in cancer
-
Yang X, Han H, De Carvalho DD, et al. Gene body methylation can alter gene expression and is a therapeutic target in cancer. Cancer Cell 2014;26(4):577-90
-
(2014)
Cancer Cell
, vol.26
, Issue.4
, pp. 577-590
-
-
Yang, X.1
Han, H.2
De Carvalho, D.D.3
-
37
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
TCGA. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008; 455(7216):1061-8 Available from: https://tcga-data.nci.nih.gov/ tcga/
-
(2008)
Nature
, vol.455
, Issue.7216
, pp. 1061-1068
-
-
-
38
-
-
85027954125
-
DNA methylation profiling in the clinic: Applications and challenges
-
Heyn H, Esteller M. DNA methylation profiling in the clinic: applications and challenges. Nat Rev Genet 2012;13(10): 679-92
-
(2012)
Nat Rev Genet
, vol.13
, Issue.10
, pp. 679-692
-
-
Heyn, H.1
Esteller, M.2
-
39
-
-
78649383152
-
Cancer epigenetics
-
Taby R, Issa JP. Cancer epigenetics. CA Cancer J Clin 2010;60(6):376-92
-
(2010)
CA Cancer J Clin
, vol.60
, Issue.6
, pp. 376-392
-
-
Taby, R.1
Issa, J.P.2
-
40
-
-
77952555038
-
Exciting new advances in neuro-oncology: The avenue to a cure for malignant glioma
-
Van Meir EG, Hadjipanayis CG, Norden AD, et al. Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma. CA Cancer J Clin 2010; 60(3):166-93
-
(2010)
CA Cancer J Clin
, vol.60
, Issue.3
, pp. 166-193
-
-
Van Meir, E.G.1
Hadjipanayis, C.G.2
Norden, A.D.3
-
41
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens AC, Gorlia T, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 2005;352(10):997-1003
-
(2005)
N Engl J Med
, vol.352
, Issue.10
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
-
42
-
-
75849146316
-
MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma
-
Rivera AL, Pelloski CE, Gilbert MR, et al. MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma. Neuro Oncol 2010;12(2):116-21
-
(2010)
Neuro Oncol
, vol.12
, Issue.2
, pp. 116-121
-
-
Rivera, A.L.1
Pelloski, C.E.2
Gilbert, M.R.3
-
43
-
-
84891785971
-
Dose-dense temozolomide for newly diagnosed glioblastoma: A randomized phase III clinical trial
-
Gilbert MR, Wang M, Aldape KD, et al. Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial. J Clin Oncol 2013;31(32): 4085-91
-
(2013)
J Clin Oncol
, vol.31
, Issue.32
, pp. 4085-4091
-
-
Gilbert, M.R.1
Wang, M.2
Aldape, K.D.3
-
44
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA IDH1 EGFR and NF1
-
Verhaak RG, Hoadley KA, Purdom E, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 2010; 17(1):98-110
-
(2010)
Cancer Cell
, vol.17
, Issue.1
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
-
45
-
-
77952108366
-
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
-
Noushmehr H, Weisenberger DJ, Diefes K, et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 2010; 17(5):510-22
-
(2010)
Cancer Cell
, vol.17
, Issue.5
, pp. 510-522
-
-
Noushmehr, H.1
Weisenberger, D.J.2
Diefes, K.3
-
46
-
-
84858796263
-
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
-
Turcan S, Rohle D, Goenka A, et al. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature 2012;483(7390):479-83
-
(2012)
Nature
, vol.483
, Issue.7390
, pp. 479-483
-
-
Turcan, S.1
Rohle, D.2
Goenka, A.3
-
47
-
-
84885074034
-
The somatic genomic landscape of glioblastoma
-
Brennan CW, Verhaak RG, McKenna A, et al. The somatic genomic landscape of glioblastoma. Cell 2013;155(2):462-77
-
(2013)
Cell
, vol.155
, Issue.2
, pp. 462-477
-
-
Brennan, C.W.1
Verhaak, R.G.2
McKenna, A.3
-
48
-
-
84867606428
-
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma
-
Sturm D, Witt H, Hovestadt V, et al. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell 2012;22(4):425-37 .. This study identified a new molecular classification of glioblastoma.
-
(2012)
Cancer Cell
, vol.22
, Issue.4
, pp. 425-437
-
-
Sturm, D.1
Witt, H.2
Hovestadt, V.3
-
49
-
-
84892805731
-
Cancer statistics, 2014
-
Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA Cancer J Clin 2014; 64(1):9-29
-
(2014)
CA Cancer J Clin
, vol.64
, Issue.1
, pp. 9-29
-
-
Siegel, R.1
Ma, J.2
Zou, Z.3
Jemal, A.4
-
50
-
-
77956103532
-
A review of the most promising biomarkers in colorectal cancer: One step closer to targeted therapy
-
Deschoolmeester V, Baay M, Specenier P, et al. A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy. Oncologist 2010; 15(7):699-731
-
(2010)
Oncologist
, vol.15
, Issue.7
, pp. 699-731
-
-
Deschoolmeester, V.1
Baay, M.2
Specenier, P.3
-
51
-
-
0037379737
-
Characterization of sporadic colon cancer by patterns of genomic instability
-
Goel A, Arnold CN, Niedzwiecki D, et al. Characterization of sporadic colon cancer by patterns of genomic instability. Cancer Res 2003;63(7):1608-14
-
(2003)
Cancer Res
, vol.63
, Issue.7
, pp. 1608-1614
-
-
Goel, A.1
Arnold, C.N.2
Niedzwiecki, D.3
-
53
-
-
32944478445
-
Mutually exclusive promoter hypermethylation patterns of hMLH1 and O6-methylguanine DNA methyltransferase in colorectal cancer
-
Fox EJ, Leahy DT, Geraghty R, et al. Mutually exclusive promoter hypermethylation patterns of hMLH1 and O6-methylguanine DNA methyltransferase in colorectal cancer. J Mol Diagn 2006; 8(1):68-75
-
(2006)
J Mol Diagn
, vol.8
, Issue.1
, pp. 68-75
-
-
Fox, E.J.1
Leahy, D.T.2
Geraghty, R.3
-
54
-
-
84877095945
-
Promoter CpG island hypermethylation of the DNA repair enzyme MGMT predicts clinical response to dacarbazine in a phase II study for metastatic colorectal cancer
-
Amatu A, Sartore-Bianchi A, Moutinho C, et al. Promoter CpG island hypermethylation of the DNA repair enzyme MGMT predicts clinical response to dacarbazine in a phase II study for metastatic colorectal cancer. Clin Cancer Res 2013;19(8):2265-72
-
(2013)
Clin Cancer Res
, vol.19
, Issue.8
, pp. 2265-2272
-
-
Amatu, A.1
Sartore-Bianchi, A.2
Moutinho, C.3
-
55
-
-
84877646733
-
A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter
-
Hochhauser D, Glynne-Jones R, Potter V, et al. A phase II study of temozolomide in patients with advanced aerodigestive tract and colorectal cancers and methylation of the O6-methylguanine-DNA methyltransferase promoter. Mol Cancer Ther 2013;12(5):809-18
-
(2013)
Mol Cancer Ther
, vol.12
, Issue.5
, pp. 809-818
-
-
Hochhauser, D.1
Glynne-Jones, R.2
Potter, V.3
-
56
-
-
17144425402
-
Hypermethylation of CpG island in O6-methylguanine-DNA methyltransferase gene was associated with K-ras G to A mutation in colorectal tumor
-
Qi J, Zhu YQ, Huang MF, Yang D. Hypermethylation of CpG island in O6-methylguanine-DNA methyltransferase gene was associated with K-ras G to A mutation in colorectal tumor. World J Gastroenterol 2005;11(13):2022-5
-
(2005)
World J Gastroenterol
, vol.11
, Issue.13
, pp. 2022-2025
-
-
Qi, J.1
Zhu, Y.Q.2
Huang, M.F.3
Yang, D.4
-
57
-
-
0033587747
-
CpG island methylator phenotype in colorectal cancer
-
Toyota M, Ahuja N, Ohe-Toyota M, et al. CpG island methylator phenotype in colorectal cancer. Proc Natl Acad Sci USA 1999;96(15):8681-6
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.15
, pp. 8681-8686
-
-
Toyota, M.1
Ahuja, N.2
Ohe-Toyota, M.3
-
58
-
-
74949089956
-
Three DNA methylation epigenotypes in human colorectal cancer
-
Yagi K, Akagi K, Hayashi H, et al. Three DNA methylation epigenotypes in human colorectal cancer. Clin Cancer Res 2010; 16(1):21-33 .. This is the most update study in the classification of colorectal cancer based on DNA methylation signatures.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.1
, pp. 21-33
-
-
Yagi, K.1
Akagi, K.2
Hayashi, H.3
-
59
-
-
38149135181
-
Clinicopathological features of CpG island methylator phenotype-positive colorectal cancer and its adverse prognosis in relation to KRAS/BRAF mutation
-
Lee S, Cho NY, Choi M, et al. Clinicopathological features of CpG island methylator phenotype-positive colorectal cancer and its adverse prognosis in relation to KRAS/BRAF mutation. Pathol Int 2008; 58(2):104-13
-
(2008)
Pathol Int
, vol.58
, Issue.2
, pp. 104-113
-
-
Lee, S.1
Cho, N.Y.2
Choi, M.3
-
60
-
-
0034847481
-
CpG island methylation in colorectal adenomas
-
Rashid A, Shen L, Morris JS, et al. CpG island methylation in colorectal adenomas. Am J Pathol 2001;159(3):1129-35
-
(2001)
Am J Pathol
, vol.159
, Issue.3
, pp. 1129-1135
-
-
Rashid, A.1
Shen, L.2
Morris, J.S.3
-
61
-
-
84907985495
-
The BRAF oncoprotein functions through the transcriptional repressor MAFG to mediate the CpG Island methylator phenotype
-
Fang M, Ou J, Hutchinson L, Green MR. The BRAF oncoprotein functions through the transcriptional repressor MAFG to mediate the CpG Island methylator phenotype. Mol Cell 2014;55(6):904-15
-
(2014)
Mol Cell
, vol.55
, Issue.6
, pp. 904-915
-
-
Fang, M.1
Ou, J.2
Hutchinson, L.3
Green, M.R.4
-
62
-
-
79955049300
-
LINE-1 hypomethylation during primary colon cancer progression
-
Sunami E, de Maat M, Vu A, et al. LINE-1 hypomethylation during primary colon cancer progression. PLoS One 2011; 6(4):e18884
-
(2011)
PLoS One
, vol.6
, Issue.4
, pp. e18884
-
-
Sunami, E.1
De Maat, M.2
Vu, A.3
-
63
-
-
84890428244
-
Epigenetic status of LINE-1 predicts clinical outcome in early-stage rectal cancer
-
Benard A, van de Velde CJ, Lessard L, et al. Epigenetic status of LINE-1 predicts clinical outcome in early-stage rectal cancer. Br J Cancer 2013;109(12):3073-83
-
(2013)
Br J Cancer
, vol.109
, Issue.12
, pp. 3073-3083
-
-
Benard, A.1
Van De Velde, C.J.2
Lessard, L.3
-
64
-
-
9344244741
-
Epigenetic inactivation of ID4 in colorectal carcinomas correlates with poor differentiation and unfavorable prognosis
-
Umetani N, Takeuchi H, Fujimoto A, et al. Epigenetic inactivation of ID4 in colorectal carcinomas correlates with poor differentiation and unfavorable prognosis. Clin Cancer Res 2004;10(22):7475-83
-
(2004)
Clin Cancer Res
, vol.10
, Issue.22
, pp. 7475-7483
-
-
Umetani, N.1
Takeuchi, H.2
Fujimoto, A.3
-
65
-
-
8844281553
-
Allelic imbalance of APAF-1 locus at 12q23 is related to progression of colorectal carcinoma
-
Umetani N, Fujimoto A, Takeuchi H, et al. Allelic imbalance of APAF-1 locus at 12q23 is related to progression of colorectal carcinoma. Oncogene 2004;23(50): 8292-300
-
(2004)
Oncogene
, vol.23
, Issue.50
, pp. 8292-8300
-
-
Umetani, N.1
Fujimoto, A.2
Takeuchi, H.3
-
66
-
-
33744822975
-
Methylation of p16 and Ras association domain family protein 1a during colorectal malignant transformation
-
Umetani N, de Maat MF, Sunami E, et al. Methylation of p16 and Ras association domain family protein 1a during colorectal malignant transformation. Mol Cancer Res 2006;4(5):303-9
-
(2006)
Mol Cancer Res
, vol.4
, Issue.5
, pp. 303-309
-
-
Umetani, N.1
De Maat, M.F.2
Sunami, E.3
-
67
-
-
33749557860
-
Comparative analysis of mesenteric and peripheral blood circulating tumor DNA in colorectal cancer patients
-
Taback B, Saha S, Hoon DS. Comparative analysis of mesenteric and peripheral blood circulating tumor DNA in colorectal cancer patients. Ann N Y Acad Sci 2006;1075: 197-203
-
(2006)
Ann N y Acad Sci
, vol.1075
, pp. 197-203
-
-
Taback, B.1
Saha, S.2
Hoon, D.S.3
-
68
-
-
34250191386
-
Assessment of methylation events during colorectal tumor progression by absolute quantitative analysis of methylated alleles
-
de Maat MF, Umetani N, Sunami E, et al. Assessment of methylation events during colorectal tumor progression by absolute quantitative analysis of methylated alleles. Mol Cancer Res 2007;5(5):461-71
-
(2007)
Mol Cancer Res
, vol.5
, Issue.5
, pp. 461-471
-
-
De Maat, M.F.1
Umetani, N.2
Sunami, E.3
-
69
-
-
67649635452
-
N-Myc downstream-regulated gene 4 (NDRG4): A candidate tumor suppressor gene and potential biomarker for colorectal cancer
-
Melotte V, Lentjes MH, van den Bosch SM, et al. N-Myc downstream-regulated gene 4 (NDRG4): a candidate tumor suppressor gene and potential biomarker for colorectal cancer. J Natl Cancer Inst 2009;101(13): 916-27
-
(2009)
J Natl Cancer Inst
, vol.101
, Issue.13
, pp. 916-927
-
-
Melotte, V.1
Lentjes, M.H.2
Van Den Bosch, S.M.3
-
70
-
-
78149329114
-
Development of sporadic microsatellite instability in colorectal tumors involves hypermethylation at methylated-in-tumor loci in adenoma
-
de Maat MF, Narita N, Benard A, et al. Development of sporadic microsatellite instability in colorectal tumors involves hypermethylation at methylated-in-tumor loci in adenoma. Am J Pathol 2010;177(5): 2347-56
-
(2010)
Am J Pathol
, vol.177
, Issue.5
, pp. 2347-2356
-
-
De Maat, M.F.1
Narita, N.2
Benard, A.3
-
71
-
-
77349107376
-
DNA methylation markers in colorectal cancer
-
Kim MS, Lee J, Sidransky D. DNA methylation markers in colorectal cancer. Cancer Metastasis Rev 2010;29(1): 181-206
-
(2010)
Cancer Metastasis Rev
, vol.29
, Issue.1
, pp. 181-206
-
-
Kim, M.S.1
Lee, J.2
Sidransky, D.3
-
72
-
-
84880063991
-
DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer
-
Carmona FJ, Azuara D, Berenguer-Llergo A, et al. DNA methylation biomarkers for noninvasive diagnosis of colorectal cancer. Cancer Prev Res (Phila) 2013;6(7):656-65
-
(2013)
Cancer Prev Res (Phila)
, vol.6
, Issue.7
, pp. 656-665
-
-
Carmona, F.J.1
Azuara, D.2
Berenguer-Llergo, A.3
-
73
-
-
84897509377
-
Multitarget stool DNA testing for colorectal-cancer screening
-
Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. N Engl J Med 2014;370(14):1287-97
-
(2014)
N Engl J Med
, vol.370
, Issue.14
, pp. 1287-1297
-
-
Imperiale, T.F.1
Ransohoff, D.F.2
Itzkowitz, S.H.3
-
74
-
-
84965187355
-
DNA methylation of apoptosis genes in rectal cancer predicts patient survival and tumor recurrence
-
Benard A, Zeestraten EC, Goossens-Beumer IJ, et al. DNA methylation of apoptosis genes in rectal cancer predicts patient survival and tumor recurrence. Apoptosis 2014;19(11): 1581-93
-
(2014)
Apoptosis
, vol.19
, Issue.11
, pp. 1581-1593
-
-
Benard, A.1
Zeestraten, E.C.2
Goossens-Beumer, I.J.3
-
75
-
-
79952717245
-
Genomic and epigenomic integration identifies a prognostic signature in colon cancer
-
Yi JM, Dhir M, Van Neste L, et al. Genomic and epigenomic integration identifies a prognostic signature in colon cancer. Clin Cancer Res 2011;17(6): 1535-45
-
(2011)
Clin Cancer Res
, vol.17
, Issue.6
, pp. 1535-1545
-
-
Yi, J.M.1
Dhir, M.2
Van Neste, L.3
-
76
-
-
84878632825
-
Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues
-
Simmer F, Brinkman AB, Assenov Y, et al. Comparative genome-wide DNA methylation analysis of colorectal tumor and matched normal tissues. Epigenetics 2012;7(12):1355-67
-
(2012)
Epigenetics
, vol.7
, Issue.12
, pp. 1355-1367
-
-
Simmer, F.1
Brinkman, A.B.2
Assenov, Y.3
-
77
-
-
84856549042
-
Genome-scale analysis of aberrant DNA methylation in colorectal cancer
-
Hinoue T, Weisenberger DJ, Lange CP, et al. Genome-scale analysis of aberrant DNA methylation in colorectal cancer. Genome Res 2012;22(2):271-82
-
(2012)
Genome Res
, vol.22
, Issue.2
, pp. 271-282
-
-
Hinoue, T.1
Weisenberger, D.J.2
Lange, C.P.3
-
78
-
-
84885008597
-
Genome-wide screening for understanding the role of DNA methylation in colorectal cancer
-
Sipos F, Muzes G, Patai AV, et al. Genome-wide screening for understanding the role of DNA methylation in colorectal cancer. Epigenomics 2013;5(5):569-81
-
(2013)
Epigenomics
, vol.5
, Issue.5
, pp. 569-581
-
-
Sipos, F.1
Muzes, G.2
Patai, A.V.3
-
79
-
-
84863922124
-
Comprehensive molecular characterization of human colon and rectal cancer
-
TCGA
-
TCGA. Comprehensive molecular characterization of human colon and rectal cancer. Nature 2012;487(7407):330-7
-
(2012)
Nature
, vol.487
, Issue.7407
, pp. 330-337
-
-
-
80
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature 2000;406(6797):747-52
-
(2000)
Nature
, vol.406
, Issue.6797
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
-
81
-
-
0025016927
-
Different methylation of oestrogen receptor DNA in human breast carcinomas with and without oestrogen receptor
-
Piva R, Rimondi AP, Hanau S, et al. Different methylation of oestrogen receptor DNA in human breast carcinomas with and without oestrogen receptor. Br J Cancer 1990;61(2):270-5
-
(1990)
Br J Cancer
, vol.61
, Issue.2
, pp. 270-275
-
-
Piva, R.1
Rimondi, A.P.2
Hanau, S.3
-
82
-
-
84903720256
-
Hypomethylation of the MMP7 promoter and increased expression of MMP7 distinguishes the basal-like breast cancer subtype from other triple-negative tumors
-
Sizemore ST, Sizemore GM, Booth CN, et al. Hypomethylation of the MMP7 promoter and increased expression of MMP7 distinguishes the basal-like breast cancer subtype from other triple-negative tumors. Breast Cancer Res Treat 2014; 146(1):25-40
-
(2014)
Breast Cancer Res Treat
, vol.146
, Issue.1
, pp. 25-40
-
-
Sizemore, S.T.1
Sizemore, G.M.2
Booth, C.N.3
-
83
-
-
84928412396
-
The prognostic value of promoter methylation in early stage triple negative breast cancer
-
Sharma P, Stecklein SR, Kimler BF, et al. The prognostic value of promoter methylation in early stage triple negative breast cancer. J Cancer Ther Res 2014;3(2): 1-11
-
(2014)
J Cancer Ther Res
, vol.3
, Issue.2
, pp. 1-11
-
-
Sharma, P.1
Stecklein, S.R.2
Kimler, B.F.3
-
84
-
-
84862640558
-
Epigenetic regulation of cancer stem cell genes in triple-negative breast cancer
-
Kagara N, Huynh KT, Kuo C, et al. Epigenetic regulation of cancer stem cell genes in triple-negative breast cancer. Am J Pathol 2012;181(1):257-67
-
(2012)
Am J Pathol
, vol.181
, Issue.1
, pp. 257-267
-
-
Kagara, N.1
Huynh, K.T.2
Kuo, C.3
-
85
-
-
84861215508
-
Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation
-
Lee H, Zhang P, Herrmann A, et al. Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation. Proc Natl Acad Sci USA 2012;109(20):7765-9
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.20
, pp. 7765-7769
-
-
Lee, H.1
Zhang, P.2
Herrmann, A.3
-
86
-
-
16844383767
-
Distinct hypermethylation profile of primary breast cancer is associated with sentinel lymph node metastasis
-
Shinozaki M, Hoon DS, Giuliano AE, et al. Distinct hypermethylation profile of primary breast cancer is associated with sentinel lymph node metastasis. Clin Cancer Res 2005;11(6):2156-62
-
(2005)
Clin Cancer Res
, vol.11
, Issue.6
, pp. 2156-2162
-
-
Shinozaki, M.1
Hoon, D.S.2
Giuliano, A.E.3
-
87
-
-
62149107439
-
Multimarker circulating DNA assay for assessing blood of prostate cancer patients
-
Sunami E, Shinozaki M, Higano CS, et al. Multimarker circulating DNA assay for assessing blood of prostate cancer patients. Clin Chem 2009;55(3):559-67
-
(2009)
Clin Chem
, vol.55
, Issue.3
, pp. 559-567
-
-
Sunami, E.1
Shinozaki, M.2
Higano, C.S.3
-
88
-
-
55749101607
-
Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors
-
Sunami E, Shinozaki M, Sim MS, et al. Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors. Breast Cancer Res 2008;10(3):R46
-
(2008)
Breast Cancer Res
, vol.10
, Issue.3
, pp. R46
-
-
Sunami, E.1
Shinozaki, M.2
Sim, M.S.3
-
89
-
-
61449558764
-
Analysis of methylated circulating DNA in cancer patients' blood
-
Sunami E, Vu AT, Nguyen SL, Hoon DS. Analysis of methylated circulating DNA in cancer patients' blood. Methods Mol Biol 2009;507:349-56
-
(2009)
Methods Mol Biol
, vol.507
, pp. 349-356
-
-
Sunami, E.1
Vu, A.T.2
Nguyen, S.L.3
Hoon, D.S.4
-
90
-
-
33749571963
-
Epigenetic analysis of body fluids and tumor tissues: Application of a comprehensive molecular assessment for early-stage breast cancer patients
-
Taback B, Giuliano AE, Lai R, et al. Epigenetic analysis of body fluids and tumor tissues: application of a comprehensive molecular assessment for early-stage breast cancer patients. Ann N Y Acad Sci 2006;1075:211-21
-
(2006)
Ann N y Acad Sci
, vol.1075
, pp. 211-221
-
-
Taback, B.1
Giuliano, A.E.2
Lai, R.3
-
91
-
-
22744444015
-
Aberrant hypermethylation of ID4 gene promoter region increases risk of lymph node metastasis in T1 breast cancer
-
Umetani N, Mori T, Koyanagi K, et al. Aberrant hypermethylation of ID4 gene promoter region increases risk of lymph node metastasis in T1 breast cancer. Oncogene 2005;24(29):4721-7
-
(2005)
Oncogene
, vol.24
, Issue.29
, pp. 4721-4727
-
-
Umetani, N.1
Mori, T.2
Koyanagi, K.3
-
92
-
-
84878587983
-
Assessment of DNA methylation status in early stages of breast cancer development
-
van Hoesel AQ, Sato Y, Elashoff DA, et al. Assessment of DNA methylation status in early stages of breast cancer development. Br J Cancer 2013;108(10):2033-8
-
(2013)
Br J Cancer
, vol.108
, Issue.10
, pp. 2033-2038
-
-
Van Hoesel, A.Q.1
Sato, Y.2
Elashoff, D.A.3
-
93
-
-
84868211985
-
Hypomethylation of LINE-1 in primary tumor has poor prognosis in young breast cancer patients: A retrospective cohort study
-
van Hoesel AQ, van de Velde CJ, Kuppen PJ, et al. Hypomethylation of LINE-1 in primary tumor has poor prognosis in young breast cancer patients: a retrospective cohort study. Breast Cancer Res Treat 2012;134(3):1103-14
-
(2012)
Breast Cancer Res Treat
, vol.134
, Issue.3
, pp. 1103-1114
-
-
Van Hoesel, A.Q.1
Van De Velde, C.J.2
Kuppen, P.J.3
-
94
-
-
84856236200
-
Primary tumor classification according to methylation pattern is prognostic in patients with early stage ER-negative breast cancer
-
van Hoesel AQ, van de Velde CJ, Kuppen PJ, et al. Primary tumor classification according to methylation pattern is prognostic in patients with early stage ER-negative breast cancer. Breast Cancer Res Treat 2012;131(3):859-69
-
(2012)
Breast Cancer Res Treat
, vol.131
, Issue.3
, pp. 859-869
-
-
Van Hoesel, A.Q.1
Van De Velde, C.J.2
Kuppen, P.J.3
-
95
-
-
77956058519
-
Simultaneous analysis of the methylation profile of 26 cancer related regions in invasive breast carcinomas by MS-MLPA and drMS-MLPA
-
Marzese DM, Gago FE, Vargas-Roig LM, Roque M. Simultaneous analysis of the methylation profile of 26 cancer related regions in invasive breast carcinomas by MS-MLPA and drMS-MLPA. Mol Cell Probes 2010;24(5):271-80
-
(2010)
Mol Cell Probes
, vol.24
, Issue.5
, pp. 271-280
-
-
Marzese, D.M.1
Gago, F.E.2
Vargas-Roig, L.M.3
Roque, M.4
-
96
-
-
84867403953
-
DNA methylation index and methylation profile of invasive ductal breast tumors
-
Marzese DM, Hoon DS, Chong KK, et al. DNA methylation index and methylation profile of invasive ductal breast tumors. J Mol Diagn 2012;14(6):613-22
-
(2012)
J Mol Diagn
, vol.14
, Issue.6
, pp. 613-622
-
-
Marzese, D.M.1
Hoon, D.S.2
Chong, K.K.3
-
97
-
-
84884588875
-
CpG island shore methylation regulates caveolin-1 expression in breast cancer
-
Rao X, Evans J, Chae H, et al. CpG island shore methylation regulates caveolin-1 expression in breast cancer. Oncogene 2013;32(38):4519-28
-
(2013)
Oncogene
, vol.32
, Issue.38
, pp. 4519-4528
-
-
Rao, X.1
Evans, J.2
Chae, H.3
-
98
-
-
84924571057
-
Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis
-
Fleischer T, Frigessi A, Johnson KC, et al. Genome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis. Genome Biol 2014;15(8):435
-
(2014)
Genome Biol
, vol.15
, Issue.8
, pp. 435
-
-
Fleischer, T.1
Frigessi, A.2
Johnson, K.C.3
-
99
-
-
84885905391
-
Integrated analysis of genome-wide DNA methylation and gene expression profiles in molecular subtypes of breast cancer
-
Rhee JK, Kim K, Chae H, et al. Integrated analysis of genome-wide DNA methylation and gene expression profiles in molecular subtypes of breast cancer. Nucleic Acids Res 2013;41(18):8464-74
-
(2013)
Nucleic Acids Res
, vol.41
, Issue.18
, pp. 8464-8474
-
-
Rhee, J.K.1
Kim, K.2
Chae, H.3
-
100
-
-
84893860385
-
Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry
-
Ambrosone CB, Young AC, Sucheston LE, et al. Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry. Oncotarget 2014;5(1):237-48
-
(2014)
Oncotarget
, vol.5
, Issue.1
, pp. 237-248
-
-
Ambrosone, C.B.1
Young, A.C.2
Sucheston, L.E.3
-
101
-
-
84918835649
-
Genome-wide DNA methylation profiling reveals parity-associated hypermethylation of FOXA1
-
Ghosh S, Gu F, Wang CM, et al. Genome-wide DNA methylation profiling reveals parity-associated hypermethylation of FOXA1. Breast Cancer Res Treat 2014; 147(3):653-9
-
(2014)
Breast Cancer Res Treat
, vol.147
, Issue.3
, pp. 653-659
-
-
Ghosh, S.1
Gu, F.2
Wang, C.M.3
-
102
-
-
84892613108
-
Age-related DNA methylation in normal breast tissue and its relationship with invasive breast tumor methylation
-
Johnson KC, Koestler DC, Cheng C, Christensen BC. Age-related DNA methylation in normal breast tissue and its relationship with invasive breast tumor methylation. Epigenetics 2014;9(2): 268-75
-
(2014)
Epigenetics
, vol.9
, Issue.2
, pp. 268-275
-
-
Johnson, K.C.1
Koestler, D.C.2
Cheng, C.3
Christensen, B.C.4
-
103
-
-
84905672549
-
Whole genome DNA methylation signature of HER2-positive breast cancer
-
Lindqvist BM, Wingren S, Motlagh PB, Nilsson TK. Whole genome DNA methylation signature of HER2-positive breast cancer. Epigenetics 2014;9(8):1149-62
-
(2014)
Epigenetics
, vol.9
, Issue.8
, pp. 1149-1162
-
-
Lindqvist, B.M.1
Wingren, S.2
Motlagh, P.B.3
Nilsson, T.K.4
-
104
-
-
84908087753
-
Differential DNA methylation status between breast carcinomatous and normal tissues
-
Wang F, Yang Y, Fu Z, et al. Differential DNA methylation status between breast carcinomatous and normal tissues. Biomed Pharmacother 2014;68(6):699-707
-
(2014)
Biomed Pharmacother
, vol.68
, Issue.6
, pp. 699-707
-
-
Wang, F.1
Yang, Y.2
Fu, Z.3
-
105
-
-
84877028141
-
Comprehensive molecular portraits of human breast tumours
-
TCGA
-
TCGA. Comprehensive molecular portraits of human breast tumours. Nature 2012; 490(7418):61-70 .. The Cancer Genome Atlas study identified five breast cancer DNA methylation subtypes.
-
(2012)
Nature
, vol.490
, Issue.7418
, pp. 61-70
-
-
-
106
-
-
84928388873
-
The CpG island methylator phenotype in breast cancer is associated with the lobular subtype
-
Roessler J, Ammerpohl O, Gutwein J, et al. The CpG island methylator phenotype in breast cancer is associated with the lobular subtype. Epigenomics 2014;1-13
-
(2014)
Epigenomics
, pp. 1-13
-
-
Roessler, J.1
Ammerpohl, O.2
Gutwein, J.3
-
107
-
-
84864258996
-
A landscape of driver mutations in melanoma
-
Hodis E, Watson IR, Kryukov GV, et al. A landscape of driver mutations in melanoma. Cell 2012;150(2):251-63
-
(2012)
Cell
, vol.150
, Issue.2
, pp. 251-263
-
-
Hodis, E.1
Watson, I.R.2
Kryukov, G.V.3
-
109
-
-
0037380925
-
Epigenetic inactivation of RAS association domain family protein 1 (RASSF1A) in malignant cutaneous melanoma
-
Spugnardi M, Tommasi S, Dammann R, et al. Epigenetic inactivation of RAS association domain family protein 1 (RASSF1A) in malignant cutaneous melanoma. Cancer Res 2003;63(7):1639-43
-
(2003)
Cancer Res
, vol.63
, Issue.7
, pp. 1639-1643
-
-
Spugnardi, M.1
Tommasi, S.2
Dammann, R.3
-
110
-
-
2542522279
-
Profiling epigenetic inactivation of tumor suppressor genes in tumors and plasma from cutaneous melanoma patients
-
Hoon DS, Spugnardi M, Kuo C, et al. Profiling epigenetic inactivation of tumor suppressor genes in tumors and plasma from cutaneous melanoma patients. Oncogene 2004;23(22):4014-22
-
(2004)
Oncogene
, vol.23
, Issue.22
, pp. 4014-4022
-
-
Hoon, D.S.1
Spugnardi, M.2
Kuo, C.3
-
111
-
-
16444373352
-
Epigenetic up-regulation of C-C chemokine receptor 7 and C-X-C chemokine receptor 4 expression in melanoma cells
-
Mori T, Kim J, Yamano T, et al. Epigenetic up-regulation of C-C chemokine receptor 7 and C-X-C chemokine receptor 4 expression in melanoma cells. Cancer Res 2005;65(5):1800-7
-
(2005)
Cancer Res
, vol.65
, Issue.5
, pp. 1800-1807
-
-
Mori, T.1
Kim, J.2
Yamano, T.3
-
112
-
-
33644828776
-
Predictive utility of circulating methylated DNA in serum of melanoma patients receiving biochemotherapy
-
Mori T, O'Day SJ, Umetani N, et al. Predictive utility of circulating methylated DNA in serum of melanoma patients receiving biochemotherapy. J Clin Oncol 2005;23(36):9351-8
-
(2005)
J Clin Oncol
, vol.23
, Issue.36
, pp. 9351-9358
-
-
Mori, T.1
O'Day, S.J.2
Umetani, N.3
-
113
-
-
33745700207
-
Association of circulating tumor cells with serum tumor-related methylated DNA in peripheral blood of melanoma patients
-
Koyanagi K, Mori T, O'Day SJ, et al. Association of circulating tumor cells with serum tumor-related methylated DNA in peripheral blood of melanoma patients. Cancer Res 2006;66(12):6111-17
-
(2006)
Cancer Res
, vol.66
, Issue.12
, pp. 6111-6117
-
-
Koyanagi, K.1
Mori, T.2
O'Day, S.J.3
-
114
-
-
33746159061
-
Estrogen receptor-alpha methylation predicts melanoma progression
-
Mori T, Martinez SR, O'Day SJ, et al. Estrogen receptor-alpha methylation predicts melanoma progression. Cancer Res 2006; 66(13):6692-8
-
(2006)
Cancer Res
, vol.66
, Issue.13
, pp. 6692-6698
-
-
Mori, T.1
Martinez, S.R.2
O'Day, S.J.3
-
115
-
-
65649092616
-
Regulation of RUNX3 tumor suppressor gene expression in cutaneous melanoma
-
Kitago M, Martinez SR, Nakamura T, et al. Regulation of RUNX3 tumor suppressor gene expression in cutaneous melanoma. Clin Cancer Res 2009;15(9):2988-94
-
(2009)
Clin Cancer Res
, vol.15
, Issue.9
, pp. 2988-2994
-
-
Kitago, M.1
Martinez, S.R.2
Nakamura, T.3
-
116
-
-
79952421239
-
Downregulation of microRNA-29c is associated with hypermethylation of tumor-related genes and disease outcome in cutaneous melanoma
-
Nguyen T, Kuo C, Nicholl MB, et al. Downregulation of microRNA-29c is associated with hypermethylation of tumor-related genes and disease outcome in cutaneous melanoma. Epigenetics 2011;6(3): 388-94
-
(2011)
Epigenetics
, vol.6
, Issue.3
, pp. 388-394
-
-
Nguyen, T.1
Kuo, C.2
Nicholl, M.B.3
-
117
-
-
84862824075
-
AIM1 and LINE-1 epigenetic aberrations in tumor and serum relate to melanoma progression and disease outcome
-
Hoshimoto S, Kuo CT, Chong KK, et al. AIM1 and LINE-1 epigenetic aberrations in tumor and serum relate to melanoma progression and disease outcome. J Invest Dermatol 2012;132(6):1689-97
-
(2012)
J Invest Dermatol
, vol.132
, Issue.6
, pp. 1689-1697
-
-
Hoshimoto, S.1
Kuo, C.T.2
Chong, K.K.3
-
118
-
-
84861613523
-
Aberrant hypermethylation in primary tumours and sentinel lymph node metastases in paediatric patients with cutaneous melanoma
-
Huynh KT, Takei Y, Kuo C, et al. Aberrant hypermethylation in primary tumours and sentinel lymph node metastases in paediatric patients with cutaneous melanoma. Br J Dermatol 2012; 166(6):1319-26
-
(2012)
Br J Dermatol
, vol.166
, Issue.6
, pp. 1319-1326
-
-
Huynh, K.T.1
Takei, Y.2
Kuo, C.3
-
119
-
-
84884915253
-
Epigenetic regulation of REG1A and chemosensitivity of cutaneous melanoma
-
Sato Y, Marzese DM, Ohta K, et al. Epigenetic regulation of REG1A and chemosensitivity of cutaneous melanoma. Epigenetics 2013;8(10):1043-52
-
(2013)
Epigenetics
, vol.8
, Issue.10
, pp. 1043-1052
-
-
Sato, Y.1
Marzese, D.M.2
Ohta, K.3
-
120
-
-
84885227935
-
Epigenetics of melanoma: Implications for immune-based therapies
-
Fratta E, Sigalotti L, Covre A, et al. Epigenetics of melanoma: implications for immune-based therapies. Immunotherapy 2013;5(10):1103-16
-
(2013)
Immunotherapy
, vol.5
, Issue.10
, pp. 1103-1116
-
-
Fratta, E.1
Sigalotti, L.2
Covre, A.3
-
122
-
-
79952585519
-
DNA-methylation profiling distinguishes malignant melanomas from benign nevi
-
Conway K, Edmiston SN, Khondker ZS, et al. DNA-methylation profiling distinguishes malignant melanomas from benign nevi. Pigment Cell Melanoma Res 2011;24(2):352-60
-
(2011)
Pigment Cell Melanoma Res
, vol.24
, Issue.2
, pp. 352-360
-
-
Conway, K.1
Edmiston, S.N.2
Khondker, Z.S.3
-
123
-
-
84865662831
-
Whole genome methylation profiles as independent markers of survival in stage IIIC melanoma patients
-
Sigalotti L, Covre A, Fratta E, et al. Whole genome methylation profiles as independent markers of survival in stage IIIC melanoma patients. J Transl Med 2012;10:185
-
(2012)
J Transl Med
, vol.10
, pp. 185
-
-
Sigalotti, L.1
Covre, A.2
Fratta, E.3
-
124
-
-
84919861005
-
Multi-platform genome-wide analysis of melanoma progression to brain metastasis
-
Marzese DM, Huynh JL, Kawas NP, Hoon DSB. Multi-platform genome-wide analysis of melanoma progression to brain metastasis. Genom Data 2014;2:150-2
-
(2014)
Genom Data
, vol.2
, pp. 150-152
-
-
Marzese, D.M.1
Huynh, J.L.2
Kawas, N.P.3
Dsb, H.4
-
125
-
-
84919851502
-
DNA methylation and gene deletion analysis of brain metastases in melanoma patients identifies mutually exclusive molecular alterations
-
Marzese DM, Scolyer RA, Roque M, et al. DNA methylation and gene deletion analysis of brain metastases in melanoma patients identifies mutually exclusive molecular alterations. Neuro Oncol 2014; 16(11):1499-509
-
(2014)
Neuro Oncol
, vol.16
, Issue.11
, pp. 1499-1509
-
-
Marzese, D.M.1
Scolyer, R.A.2
Roque, M.3
-
126
-
-
84919846591
-
Brain metastasis is predetermined in early stages of cutaneous melanoma by CD44v6 expression through epigenetic regulation of the spliceosome
-
Marzese DM, Liu M, Huynh JL, et al. Brain metastasis is predetermined in early stages of cutaneous melanoma by CD44v6 expression through epigenetic regulation of the spliceosome. Pigment Cell Melanoma Res 2014;28(1):82-93
-
(2014)
Pigment Cell Melanoma Res
, vol.28
, Issue.1
, pp. 82-93
-
-
Marzese, D.M.1
Liu, M.2
Huynh, J.L.3
-
127
-
-
63449140854
-
CpG island methylator phenotype predicts progression of malignant melanoma
-
Tanemura A, Terando AM, Sim MS, et al. CpG island methylator phenotype predicts progression of malignant melanoma. Clin Cancer Res 2009;15(5):1801-7
-
(2009)
Clin Cancer Res
, vol.15
, Issue.5
, pp. 1801-1807
-
-
Tanemura, A.1
Terando, A.M.2
Sim, M.S.3
-
128
-
-
84862907872
-
The BRAF(V600E) causes widespread alterations in gene methylation in the genome of melanoma cells
-
Hou P, Liu D, Dong J, Xing M. The BRAF(V600E) causes widespread alterations in gene methylation in the genome of melanoma cells. Cell cycle 2012;11(2): 286-95
-
(2012)
Cell Cycle
, vol.11
, Issue.2
, pp. 286-295
-
-
Hou, P.1
Liu, D.2
Dong, J.3
Xing, M.4
-
130
-
-
84866434919
-
Genomic landscape of non-small cell lung cancer in smokers and never-smokers
-
Govindan R, Ding L, Griffith M, et al. Genomic landscape of non-small cell lung cancer in smokers and never-smokers. Cell 2012;150(6):1121-34
-
(2012)
Cell
, vol.150
, Issue.6
, pp. 1121-1134
-
-
Govindan, R.1
Ding, L.2
Griffith, M.3
-
131
-
-
84885924300
-
PARAMOUNT: Final overall survival results of the phase III study of maintenance pemetrexed versus placebo immediately after induction treatment with pemetrexed plus cisplatin for advanced nonsquamous non-small-cell lung cancer
-
Paz-Ares LG, de Marinis F, Dediu M, et al. PARAMOUNT: final overall survival results of the phase III study of maintenance pemetrexed versus placebo immediately after induction treatment with pemetrexed plus cisplatin for advanced nonsquamous non-small-cell lung cancer. J Clin Oncol 2013;31(23):2895-902
-
(2013)
J Clin Oncol
, vol.31
, Issue.23
, pp. 2895-2902
-
-
Paz-Ares, L.G.1
De Marinis, F.2
Dediu, M.3
-
132
-
-
84891801684
-
A prognostic DNA methylation signature for stage i non-small-cell lung cancer
-
Sandoval J, Mendez-Gonzalez J, Nadal E, et al. A prognostic DNA methylation signature for stage I non-small-cell lung cancer. J Clin Oncol 2013;31(32):4140-7
-
(2013)
J Clin Oncol
, vol.31
, Issue.32
, pp. 4140-4147
-
-
Sandoval, J.1
Mendez-Gonzalez, J.2
Nadal, E.3
-
133
-
-
84905029258
-
Comprehensive molecular profiling of lung adenocarcinoma
-
TCGA
-
TCGA. Comprehensive molecular profiling of lung adenocarcinoma. Nature 2014; 511(7511):543-50
-
(2014)
Nature
, vol.511
, Issue.7511
, pp. 543-550
-
-
-
134
-
-
84866894408
-
Comprehensive genomic characterization of squamous cell lung cancers
-
TCGA
-
TCGA. Comprehensive genomic characterization of squamous cell lung cancers. Nature 2012;489(7417):519-25
-
(2012)
Nature
, vol.489
, Issue.7417
, pp. 519-525
-
-
-
135
-
-
0038275923
-
Lead times and overdetection due to prostate-specific antigen screening: Estimates from the European Randomized Study of Screening for Prostate Cancer
-
Draisma G, Boer R, Otto SJ, et al. Lead times and overdetection due to prostate-specific antigen screening: estimates from the European Randomized Study of Screening for Prostate Cancer. J Natl Cancer Inst 2003;95(12):868-78
-
(2003)
J Natl Cancer Inst
, vol.95
, Issue.12
, pp. 868-878
-
-
Draisma, G.1
Boer, R.2
Otto, S.J.3
-
136
-
-
0028152397
-
Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis
-
Lee WH, Morton RA, Epstein JI, et al. Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis. Proc Natl Acad Sci USA 1994;91(24):11733-7
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.24
, pp. 11733-11737
-
-
Lee, W.H.1
Morton, R.A.2
Epstein, J.I.3
-
137
-
-
8444220925
-
Molecular biomarker in prostate cancer: The role of CpG island hypermethylation
-
Bastian PJ, Yegnasubramanian S, Palapattu GS, et al. Molecular biomarker in prostate cancer: the role of CpG island hypermethylation. Eur Urol 2004;46(6): 698-708
-
(2004)
Eur Urol
, vol.46
, Issue.6
, pp. 698-708
-
-
Bastian, P.J.1
Yegnasubramanian, S.2
Palapattu, G.S.3
-
138
-
-
0037817323
-
Prostate cancer detection by GSTP1 methylation analysis of postbiopsy urine specimens
-
Gonzalgo ML, Pavlovich CP, Lee SM, Nelson WG. Prostate cancer detection by GSTP1 methylation analysis of postbiopsy urine specimens. Clin Cancer Res 2003; 9(7):2673-7
-
(2003)
Clin Cancer Res
, vol.9
, Issue.7
, pp. 2673-2677
-
-
Gonzalgo, M.L.1
Pavlovich, C.P.2
Lee, S.M.3
Nelson, W.G.4
-
139
-
-
0034748725
-
DNA-based detection of prostate cancer in blood, urine, and ejaculates
-
Goessl C, Muller M, Heicappell R, et al. DNA-based detection of prostate cancer in blood, urine, and ejaculates. Ann N Y Acad Sci 2001;945:51-8
-
(2001)
Ann N y Acad Sci
, vol.945
, pp. 51-58
-
-
Goessl, C.1
Muller, M.2
Heicappell, R.3
-
140
-
-
0036899057
-
Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer
-
Jeronimo C, Usadel H, Henrique R, et al. Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer. Urology 2002;60(6):1131-5
-
(2002)
Urology
, vol.60
, Issue.6
, pp. 1131-1135
-
-
Jeronimo, C.1
Usadel, H.2
Henrique, R.3
-
141
-
-
79959686697
-
Measurement of GSTP1 promoter methylation in body fluids may complement PSA screening: A meta-analysis
-
Wu T, Giovannucci E, Welge J, et al. Measurement of GSTP1 promoter methylation in body fluids may complement PSA screening: a meta-analysis. Br J Cancer 2011;105(1):65-73
-
(2011)
Br J Cancer
, vol.105
, Issue.1
, pp. 65-73
-
-
Wu, T.1
Giovannucci, E.2
Welge, J.3
-
142
-
-
0019513712
-
Determination of 5-methylcytosine from plant DNA by high-performance liquid chromatography
-
Wagner I, Capesius I. Determination of 5-methylcytosine from plant DNA by high-performance liquid chromatography. Biochim Biophys Acta 1981;654(1):52-6
-
(1981)
Biochim Biophys Acta
, vol.654
, Issue.1
, pp. 52-56
-
-
Wagner, I.1
Capesius, I.2
-
143
-
-
0032894211
-
Global DNA hypomethylation in breast carcinoma: Correlation with prognostic factors and tumor progression
-
Soares J, Pinto AE, Cunha CV, et al. Global DNA hypomethylation in breast carcinoma: correlation with prognostic factors and tumor progression. Cancer 1999;85(1):112-18
-
(1999)
Cancer
, vol.85
, Issue.1
, pp. 112-118
-
-
Soares, J.1
Pinto, A.E.2
Cunha, C.V.3
-
144
-
-
84876944890
-
Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry
-
Chen ML, Shen F, Huang W, et al. Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry. Clin Chem 2013;59(5): 824-32
-
(2013)
Clin Chem
, vol.59
, Issue.5
, pp. 824-832
-
-
Chen, M.L.1
Shen, F.2
Huang, W.3
-
145
-
-
84881663694
-
Prognostic role of immunohistochemical analysis of 5 mc in myelodysplastic syndromes
-
Poloni A, Goteri G, Zizzi A, et al. Prognostic role of immunohistochemical analysis of 5 mc in myelodysplastic syndromes. Eur J Haematol 2013;91(3): 219-27
-
(2013)
Eur J Haematol
, vol.91
, Issue.3
, pp. 219-227
-
-
Poloni, A.1
Goteri, G.2
Zizzi, A.3
-
146
-
-
84891858084
-
Temozolomide downregulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/ glycogen synthase-3 kinase/beta-catenin pathway
-
Riganti C, Salaroglio IC, Caldera V, et al. Temozolomide downregulates P-glycoprotein expression in glioblastoma stem cells by interfering with the Wnt3a/ glycogen synthase-3 kinase/beta-catenin pathway. Neuro Oncol 2013;15(11): 1502-17
-
(2013)
Neuro Oncol
, vol.15
, Issue.11
, pp. 1502-1517
-
-
Riganti, C.1
Salaroglio, I.C.2
Caldera, V.3
-
147
-
-
0029843950
-
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
-
Herman JG, Graff JR, Myohanen S, et al. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 1996;93(18): 9821-6
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.18
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
-
148
-
-
0033566692
-
Quantitative analysis of aberrant p16 methylation using real-time quantitative methylation-specific polymerase chain reaction
-
Lo YM, Wong IH, Zhang J, et al. Quantitative analysis of aberrant p16 methylation using real-time quantitative methylation-specific polymerase chain reaction. Cancer Res 1999;59(16):3899-903
-
(1999)
Cancer Res
, vol.59
, Issue.16
, pp. 3899-3903
-
-
Lo, Y.M.1
Wong, I.H.2
Zhang, J.3
-
149
-
-
0034654669
-
MethyLight: A high-throughput assay to measure DNA methylation
-
Eads CA, Danenberg KD, Kawakami K, et al. MethyLight: a high-throughput assay to measure DNA methylation. Nucleic Acids Res 2000;28(8):E32
-
(2000)
Nucleic Acids Res
, vol.28
, Issue.8
, pp. E32
-
-
Eads, C.A.1
Danenberg, K.D.2
Kawakami, K.3
-
150
-
-
0038678777
-
Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sites
-
Colella S, Shen L, Baggerly KA, et al. Sensitive and quantitative universal Pyrosequencing methylation analysis of CpG sites. Biotechniques 2003;35(1): 146-50
-
(2003)
Biotechniques
, vol.35
, Issue.1
, pp. 146-150
-
-
Colella, S.1
Shen, L.2
Baggerly, K.A.3
-
151
-
-
34547528183
-
DNA methylation: Bisulphite modification and analysis
-
Clark SJ, Statham A, Stirzaker C, et al. DNA methylation: bisulphite modification and analysis. Nat Protoc 2006;1(5):2353-64
-
(2006)
Nat Protoc
, vol.1
, Issue.5
, pp. 2353-2364
-
-
Clark, S.J.1
Statham, A.2
Stirzaker, C.3
-
152
-
-
84928382928
-
Genome-wide hypomethylation and specific tumor-related gene hypermethylation are associated with esophageal squamous cell carcinoma outcome
-
Hoshimoto S, Takeuchi H, Ono S, et al. Genome-wide hypomethylation and specific tumor-related gene hypermethylation are associated with esophageal squamous cell carcinoma outcome. J Thorac Oncol 2015; 10(3):509-17
-
(2015)
J Thorac Oncol
, vol.10
, Issue.3
, pp. 509-517
-
-
Hoshimoto, S.1
Takeuchi, H.2
Ono, S.3
-
153
-
-
0021339952
-
Mouse mammary tumor virus: Specific methylation patterns of proviral DNA in normal mouse tissues
-
Hu WS, Fanning TG, Cardiff RD. Mouse mammary tumor virus: specific methylation patterns of proviral DNA in normal mouse tissues. J Virol 1984;49(1):66-71
-
(1984)
J Virol
, vol.49
, Issue.1
, pp. 66-71
-
-
Hu, W.S.1
Fanning, T.G.2
Cardiff, R.D.3
-
154
-
-
33746756014
-
Comparative isoschizomer profiling of cytosine methylation: The HELP assay
-
Khulan B, Thompson RF, Ye K, et al. Comparative isoschizomer profiling of cytosine methylation: the HELP assay. Genome Res 2006;16(8):1046-55
-
(2006)
Genome Res
, vol.16
, Issue.8
, pp. 1046-1055
-
-
Khulan, B.1
Thompson, R.F.2
Ye, K.3
-
155
-
-
33646870108
-
Genome-wide profiling of promoter methylation in human
-
Hatada I, Fukasawa M, Kimura M, et al. Genome-wide profiling of promoter methylation in human. Oncogene 2006; 25(21):3059-64
-
(2006)
Oncogene
, vol.25
, Issue.21
, pp. 3059-3064
-
-
Hatada, I.1
Fukasawa, M.2
Kimura, M.3
-
156
-
-
84887617516
-
Analyzing the cancer methylome through targeted bisulfite sequencing
-
Lee EJ, Luo J, Wilson JM, Shi H. Analyzing the cancer methylome through targeted bisulfite sequencing. Cancer Lett 2013;340(2):171-8
-
(2013)
Cancer Lett
, vol.340
, Issue.2
, pp. 171-178
-
-
Lee, E.J.1
Luo, J.2
Wilson, J.M.3
Shi, H.4
-
157
-
-
23044514626
-
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
-
Weber M, Davies JJ, Wittig D, et al. Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat Genet 2005; 37(8):853-62 .. This review introduced the methylated DNA immunoprecipitation technique. In this first publication, methylated DNA immunoprecipitation was coupled with a microarray.
-
(2005)
Nat Genet
, vol.37
, Issue.8
, pp. 853-862
-
-
Weber, M.1
Davies, J.J.2
Wittig, D.3
-
158
-
-
77649238322
-
DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status
-
Flanagan JM, Cocciardi S, Waddell N, et al. DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status. Am J Hum Genet 2010; 86(3):420-33
-
(2010)
Am J Hum Genet
, vol.86
, Issue.3
, pp. 420-433
-
-
Flanagan, J.M.1
Cocciardi, S.2
Waddell, N.3
-
159
-
-
77950409567
-
Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing
-
Ruike Y, Imanaka Y, Sato F, et al. Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing. BMC Genomics 2010;11:137
-
(2010)
BMC Genomics
, vol.11
, pp. 137
-
-
Ruike, Y.1
Imanaka, Y.2
Sato, F.3
-
160
-
-
84868370483
-
Genome-wide methylation profiling identifies hypermethylated biomarkers in high-grade cervical intraepithelial neoplasia
-
Lendvai A, Johannes F, Grimm C, et al. Genome-wide methylation profiling identifies hypermethylated biomarkers in high-grade cervical intraepithelial neoplasia. Epigenetics 2012;7(11):1268-78
-
(2012)
Epigenetics
, vol.7
, Issue.11
, pp. 1268-1278
-
-
Lendvai, A.1
Johannes, F.2
Grimm, C.3
-
161
-
-
84908153718
-
Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers
-
Zhang B, Xing X, Li J, et al. Comparative DNA methylome analysis of endometrial carcinoma reveals complex and distinct deregulation of cancer promoters and enhancers. BMC Genomics 2014;15(1):868
-
(2014)
BMC Genomics
, vol.15
, Issue.1
, pp. 868
-
-
Zhang, B.1
Xing, X.2
Li, J.3
-
162
-
-
84870889883
-
MeDIP coupled with a promoter tiling array as a platform to investigate global DNA methylation patterns in AML cells
-
Yalcin A, Kreutz C, Pfeifer D, et al. MeDIP coupled with a promoter tiling array as a platform to investigate global DNA methylation patterns in AML cells. Leuk Res 2013;37(1):102-11
-
(2013)
Leuk Res
, vol.37
, Issue.1
, pp. 102-111
-
-
Yalcin, A.1
Kreutz, C.2
Pfeifer, D.3
-
163
-
-
84857138378
-
Integrative genome-wide expression and promoter DNA methylation profiling identifies a potential novel panel of ovarian cancer epigenetic biomarkers
-
Gloss BS, Patterson KI, Barton CA, et al. Integrative genome-wide expression and promoter DNA methylation profiling identifies a potential novel panel of ovarian cancer epigenetic biomarkers. Cancer Lett 2012;318(1):76-85
-
(2012)
Cancer Lett
, vol.318
, Issue.1
, pp. 76-85
-
-
Gloss, B.S.1
Patterson, K.I.2
Barton, C.A.3
-
164
-
-
79953062931
-
Genome-wide methylation analysis identifies epigenetically inactivated candidate tumour suppressor genes in renal cell carcinoma
-
Morris MR, Ricketts CJ, Gentle D, et al. Genome-wide methylation analysis identifies epigenetically inactivated candidate tumour suppressor genes in renal cell carcinoma. Oncogene 2011;30(12):1390-401
-
(2011)
Oncogene
, vol.30
, Issue.12
, pp. 1390-1401
-
-
Morris, M.R.1
Ricketts, C.J.2
Gentle, D.3
-
165
-
-
75549089556
-
Genome-wide DNA methylation profiling reveals novel epigenetically regulated genes and non-coding RNAs in human testicular cancer
-
Cheung HH, Lee TL, Davis AJ, et al. Genome-wide DNA methylation profiling reveals novel epigenetically regulated genes and non-coding RNAs in human testicular cancer. Br J Cancer 2010;102(2):419-27
-
(2010)
Br J Cancer
, vol.102
, Issue.2
, pp. 419-427
-
-
Cheung, H.H.1
Lee, T.L.2
Davis, A.J.3
-
166
-
-
77957951913
-
Whole-genome DNA methylation profiling using MethylCap-seq
-
Brinkman AB, Simmer F, Ma K, et al. Whole-genome DNA methylation profiling using MethylCap-seq. Methods 2010;52(3): 232-6
-
(2010)
Methods
, vol.52
, Issue.3
, pp. 232-236
-
-
Brinkman, A.B.1
Simmer, F.2
Ma, K.3
-
167
-
-
77449127799
-
MBD-isolated Genome Sequencing provides a high-throughput and comprehensive survey of DNA methylation in the human genome
-
Serre D, Lee BH, Ting AH. MBD-isolated Genome Sequencing provides a high-throughput and comprehensive survey of DNA methylation in the human genome. Nucleic Acids Res 2010;38(2):391-9
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.2
, pp. 391-399
-
-
Serre, D.1
Lee, B.H.2
Ting, A.H.3
-
168
-
-
77957937011
-
Quantitative comparison of genome-wide DNA methylation mapping technologies
-
Bock C, Tomazou EM, Brinkman AB, et al. Quantitative comparison of genome-wide DNA methylation mapping technologies. Nat Biotechnol 2010;28(10): 1106-14
-
(2010)
Nat Biotechnol
, vol.28
, Issue.10
, pp. 1106-1114
-
-
Bock, C.1
Tomazou, E.M.2
Brinkman, A.B.3
-
169
-
-
84859829499
-
Methylcap-seq reveals novel DNA methylation markers for the diagnosis and recurrence prediction of bladder cancer in a Chinese population
-
Zhao Y, Guo S, Sun J, et al. Methylcap-seq reveals novel DNA methylation markers for the diagnosis and recurrence prediction of bladder cancer in a Chinese population. PLoS One 2012;7(4):e35175
-
(2012)
PLoS One
, vol.7
, Issue.4
, pp. e35175
-
-
Zhao, Y.1
Guo, S.2
Sun, J.3
-
170
-
-
84924599811
-
Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia
-
Niederwieser C, Kohlschmidt J, Volinia S, et al. Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia. Leukemia 2015;29(3): 567-75
-
(2015)
Leukemia
, vol.29
, Issue.3
, pp. 567-575
-
-
Niederwieser, C.1
Kohlschmidt, J.2
Volinia, S.3
-
171
-
-
84864753104
-
Genome-wide DNA methylation profiling of non-small cell lung carcinomas
-
Carvalho RH, Haberle V, Hou J, et al. Genome-wide DNA methylation profiling of non-small cell lung carcinomas. Epigenetics Chromatin 2012;5(1):9
-
(2012)
Epigenetics Chromatin
, vol.5
, Issue.1
, pp. 9
-
-
Carvalho, R.H.1
Haberle, V.2
Hou, J.3
-
172
-
-
84876407786
-
Genome-wide DNA methylation analysis identifies novel methylated genes in non-small-cell lung carcinomas
-
Carvalho RH, Hou J, Haberle V, et al. Genome-wide DNA methylation analysis identifies novel methylated genes in non-small-cell lung carcinomas. J Thorac Oncol 2013;8(5):562-73
-
(2013)
J Thorac Oncol
, vol.8
, Issue.5
, pp. 562-573
-
-
Carvalho, R.H.1
Hou, J.2
Haberle, V.3
-
173
-
-
84055182550
-
Global analysis of DNA methylation by Methyl-Capture sequencing reveals epigenetic control of cisplatin resistance in ovarian cancer cell
-
Yu W, Jin C, Lou X, et al. Global analysis of DNA methylation by Methyl-Capture sequencing reveals epigenetic control of cisplatin resistance in ovarian cancer cell. PLoS One 2011;6(12):e29450
-
(2011)
PLoS One
, vol.6
, Issue.12
, pp. e29450
-
-
Yu, W.1
Jin, C.2
Lou, X.3
-
174
-
-
84891959461
-
Comprehensive methylome analysis of ovarian tumors reveals hedgehog signaling pathway regulators as prognostic DNA methylation biomarkers
-
Huang RL, Gu F, Kirma NB, et al. Comprehensive methylome analysis of ovarian tumors reveals hedgehog signaling pathway regulators as prognostic DNA methylation biomarkers. Epigenetics 2013;8(6):624-34
-
(2013)
Epigenetics
, vol.8
, Issue.6
, pp. 624-634
-
-
Huang, R.L.1
Gu, F.2
Kirma, N.B.3
-
175
-
-
84890632231
-
The effect of VEGF-targeted therapy on biomarker expression in sequential tissue from patients with metastatic clear cell renal cancer
-
Sharpe K, Stewart GD, Mackay A, et al. The effect of VEGF-targeted therapy on biomarker expression in sequential tissue from patients with metastatic clear cell renal cancer. Clin Cancer Res 2013;19(24): 6924-34
-
(2013)
Clin Cancer Res
, vol.19
, Issue.24
, pp. 6924-6934
-
-
Sharpe, K.1
Stewart, G.D.2
Mackay, A.3
-
176
-
-
1842505317
-
Mbd1 is recruited to both methylated and nonmethylated CpGs via distinct DNA binding domains
-
Jorgensen HF, Ben-Porath I, Bird AP. Mbd1 is recruited to both methylated and nonmethylated CpGs via distinct DNA binding domains. Mol Cell Biol 2004;24(8):3387-95
-
(2004)
Mol Cell Biol
, vol.24
, Issue.8
, pp. 3387-3395
-
-
Jorgensen, H.F.1
Ben-Porath, I.2
Bird, A.P.3
-
177
-
-
84925440397
-
Molecular dynamics study of the recognition of dimethylated CpG sites by MBD1 protein
-
[Epub ahead of print]
-
Bianchi C, Zangi R. Molecular dynamics study of the recognition of dimethylated CpG sites by MBD1 protein. J Chem Inf Model 2015. [Epub ahead of print]
-
(2015)
J Chem Inf Model
-
-
Bianchi, C.1
Zangi, R.2
-
178
-
-
73649110641
-
DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia
-
Figueroa ME, Lugthart S, Li Y, et al. DNA methylation signatures identify biologically distinct subtypes in acute myeloid leukemia. Cancer Cell 2010;17(1): 13-27
-
(2010)
Cancer Cell
, vol.17
, Issue.1
, pp. 13-27
-
-
Figueroa, M.E.1
Lugthart, S.2
Li, Y.3
-
179
-
-
43149098062
-
Comprehensive high-throughput arrays for relative methylation (CHARM)
-
Irizarry RA, Ladd-Acosta C, Carvalho B, et al. Comprehensive high-throughput arrays for relative methylation (CHARM). Genome Res 2008;18(5):780-90
-
(2008)
Genome Res
, vol.18
, Issue.5
, pp. 780-790
-
-
Irizarry, R.A.1
Ladd-Acosta, C.2
Carvalho, B.3
-
180
-
-
84880909300
-
Integration of high-resolution methylome and transcriptome analyses to dissect epigenomic changes in childhood acute lymphoblastic leukemia
-
Busche S, Ge B, Vidal R, et al. Integration of high-resolution methylome and transcriptome analyses to dissect epigenomic changes in childhood acute lymphoblastic leukemia. Cancer Res 2013;73(14):4323-36
-
(2013)
Cancer Res
, vol.73
, Issue.14
, pp. 4323-4336
-
-
Busche, S.1
Ge, B.2
Vidal, R.3
-
181
-
-
84883520928
-
Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips
-
Naumov VA, Generozov EV, Zaharjevskaya NB, et al. Genome-scale analysis of DNA methylation in colorectal cancer using Infinium HumanMethylation450 BeadChips. Epigenetics 2013;8(9):921-34
-
(2013)
Epigenetics
, vol.8
, Issue.9
, pp. 921-934
-
-
Naumov, V.A.1
Generozov, E.V.2
Zaharjevskaya, N.B.3
-
182
-
-
84896700012
-
Analysis of DNA methylation patterns associated with the gastric cancer genome
-
Cheng Y, Yan Z, Liu Y, et al. Analysis of DNA methylation patterns associated with the gastric cancer genome. Oncol Lett 2014; 7(4):1021-6
-
(2014)
Oncol Lett
, vol.7
, Issue.4
, pp. 1021-1026
-
-
Cheng, Y.1
Yan, Z.2
Liu, Y.3
-
183
-
-
84912138354
-
Epigenetic activation of immune genes in cervical cancer
-
Gasperov NM, Farkas SA, Nilsson TK, Grce M. Epigenetic activation of immune genes in cervical cancer. Immunol Lett 2014;162(2 Pt B):256-7
-
(2014)
Immunol Lett
, vol.162
, Issue.2
, pp. 256-257
-
-
Gasperov, N.M.1
Farkas, S.A.2
Nilsson, T.K.3
Grce, M.4
-
184
-
-
84918512244
-
Genome-wide DNA methylation analysis of lung carcinoma reveals one neuorendocrine and four adenocarcinoma epitypes associated with patient outcome
-
Karlsson A, Jonsson M, Lauss M, et al. Genome-wide DNA methylation analysis of lung carcinoma reveals one neuorendocrine and four adenocarcinoma epitypes associated with patient outcome. Clin Cancer Res 2014;20(23):6127-40
-
(2014)
Clin Cancer Res
, vol.20
, Issue.23
, pp. 6127-6140
-
-
Karlsson, A.1
Jonsson, M.2
Lauss, M.3
-
185
-
-
84874353239
-
Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray
-
Chen YA, Lemire M, Choufani S, et al. Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray. Epigenetics 2013;8(2):203-9
-
(2013)
Epigenetics
, vol.8
, Issue.2
, pp. 203-209
-
-
Chen, Y.A.1
Lemire, M.2
Choufani, S.3
-
186
-
-
84862979818
-
Distinct DNA methylomes of newborns and centenarians
-
Heyn H, Li N, Ferreira HJ, et al. Distinct DNA methylomes of newborns and centenarians. Proc Natl Acad Sci USA 2012;109(26):10522-7
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.26
, pp. 10522-10527
-
-
Heyn, H.1
Li, N.2
Ferreira, H.J.3
-
187
-
-
79960927422
-
Increased methylation variation in epigenetic domains across cancer types
-
Hansen KD, Timp W, Bravo HC, et al. Increased methylation variation in epigenetic domains across cancer types. Nat Genet 2011;43(8):768-75
-
(2011)
Nat Genet
, vol.43
, Issue.8
, pp. 768-775
-
-
Hansen, K.D.1
Timp, W.2
Bravo, H.C.3
-
188
-
-
84655162785
-
Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains
-
Berman BP, Weisenberger DJ, Aman JF, et al. Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains. Nat Genet 2012;44(1):40-6
-
(2012)
Nat Genet
, vol.44
, Issue.1
, pp. 40-46
-
-
Berman, B.P.1
Weisenberger, D.J.2
Aman, J.F.3
-
189
-
-
27144500218
-
Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis
-
Meissner A, Gnirke A, Bell GW, et al. Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis. Nucleic Acids Res 2005;33(18):5868-77 .. This review introduced the adaptation of whole-genome bisulfite sequencing named reduced representation bisulfite sequencing.
-
(2005)
Nucleic Acids Res
, vol.33
, Issue.18
, pp. 5868-5877
-
-
Meissner, A.1
Gnirke, A.2
Bell, G.W.3
-
190
-
-
84857784165
-
Library-free methylation sequencing with bisulfite padlock probes
-
Diep D, Plongthongkum N, Gore A, et al. Library-free methylation sequencing with bisulfite padlock probes. Nat Methods 2012;9(3):270-2
-
(2012)
Nat Methods
, vol.9
, Issue.3
, pp. 270-272
-
-
Diep, D.1
Plongthongkum, N.2
Gore, A.3
-
191
-
-
84884995734
-
Tagmentation-based whole-genome bisulfite sequencing
-
Wang Q, Gu L, Adey A, et al. Tagmentation-based whole-genome bisulfite sequencing. Nat Protoc 2013;8(10):2022-32
-
(2013)
Nat Protoc
, vol.8
, Issue.10
, pp. 2022-2032
-
-
Wang, Q.1
Gu, L.2
Adey, A.3
-
192
-
-
84916928230
-
Tumor-suppressive miR148a is silenced by CpG island hypermethylation in IDH1-mutant gliomas
-
Li S, Chowdhury R, Liu F, et al. Tumor-suppressive miR148a is silenced by CpG island hypermethylation in IDH1-mutant gliomas. Clin Cancer Res 2014;20(22):5808-22
-
(2014)
Clin Cancer Res
, vol.20
, Issue.22
, pp. 5808-5822
-
-
Li, S.1
Chowdhury, R.2
Liu, F.3
-
193
-
-
84861922114
-
Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia
-
Pei L, Choi JH, Liu J, et al. Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia. Epigenetics 2012;7(6):567-78
-
(2012)
Epigenetics
, vol.7
, Issue.6
, pp. 567-578
-
-
Pei, L.1
Choi, J.H.2
Liu, J.3
-
194
-
-
84899148704
-
DNA methylome profiling identifies novel methylated genes in African American patients with colorectal neoplasia
-
Ashktorab H, Daremipouran M, Goel A, et al. DNA methylome profiling identifies novel methylated genes in African American patients with colorectal neoplasia. Epigenetics 2014;9(4):503-12
-
(2014)
Epigenetics
, vol.9
, Issue.4
, pp. 503-512
-
-
Ashktorab, H.1
Daremipouran, M.2
Goel, A.3
-
195
-
-
84885012678
-
Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine
-
Booth MJ, Ost TW, Beraldi D, et al. Oxidative bisulfite sequencing of 5-methylcytosine and 5-hydroxymethylcytosine. Nat Protoc 2013; 8(10):1841-51 . Describes an adaptation of bisulfite sequencing to distinguish 5-methylcytosine from 5-hydroxymethyl-cytocine by inducing the oxidation of 5-hydroxymethylcytocine.
-
(2013)
Nat Protoc
, vol.8
, Issue.10
, pp. 1841-1851
-
-
Booth, M.J.1
Ost, T.W.2
Beraldi, D.3
-
196
-
-
84927714053
-
OxBS-450K: A method for analysing hydroxymethylation using 450K BeadChips
-
Stewart SK, Morris TJ, Guilhamon P, et al. oxBS-450K: a method for analysing hydroxymethylation using 450K BeadChips. Methods 2015;72:9-15
-
(2015)
Methods
, vol.72
, pp. 9-15
-
-
Stewart, S.K.1
Morris, T.J.2
Guilhamon, P.3
-
197
-
-
84861990517
-
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome
-
Yu M, Hon GC, Szulwach KE, et al. Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell 2012;149(6):1368-80
-
(2012)
Cell
, vol.149
, Issue.6
, pp. 1368-1380
-
-
Yu, M.1
Hon, G.C.2
Szulwach, K.E.3
-
198
-
-
77952967431
-
Direct detection of DNA methylation during single-molecule real-time sequencing
-
Flusberg BA, Webster DR, Lee JH, et al. Direct detection of DNA methylation during single-molecule, real-time sequencing. Nat Methods 2010;7(6):461-5 . Introduces the third-generation of sequencing technologies to study DNA methylation maps.
-
(2010)
Nat Methods
, vol.7
, Issue.6
, pp. 461-465
-
-
Flusberg, B.A.1
Webster, D.R.2
Lee, J.H.3
-
199
-
-
33846619807
-
Global DNA methylation level in whole blood as a biomarker in head and neck squamous cell carcinoma
-
Hsiung DT, Marsit CJ, Houseman EA, et al. Global DNA methylation level in whole blood as a biomarker in head and neck squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev 2007;16(1): 108-14
-
(2007)
Cancer Epidemiol Biomarkers Prev
, vol.16
, Issue.1
, pp. 108-114
-
-
Hsiung, D.T.1
Marsit, C.J.2
Houseman, E.A.3
-
200
-
-
39749180354
-
DNA methylation biomarkers for blood-based colorectal cancer screening
-
Lofton-Day C, Model F, Devos T, et al. DNA methylation biomarkers for blood-based colorectal cancer screening. Clin Chem 2008;54(2):414-23
-
(2008)
Clin Chem
, vol.54
, Issue.2
, pp. 414-423
-
-
Lofton-Day, C.1
Model, F.2
Devos, T.3
-
201
-
-
79961093766
-
DNA methylation of tumor suppressor and metastasis suppressor genes in circulating tumor cells
-
Chimonidou M, Strati A, Tzitzira A, et al. DNA methylation of tumor suppressor and metastasis suppressor genes in circulating tumor cells. Clin Chem 2011;57(8): 1169-77
-
(2011)
Clin Chem
, vol.57
, Issue.8
, pp. 1169-1177
-
-
Chimonidou, M.1
Strati, A.2
Tzitzira, A.3
-
202
-
-
33947239430
-
Tumor-specific methylation in saliva: A promising biomarker for early detection of head and neck cancer recurrence
-
Righini CA, de Fraipont F, Timsit JF, et al. Tumor-specific methylation in saliva: a promising biomarker for early detection of head and neck cancer recurrence. Clin Cancer Res 2007;13(4):1179-85
-
(2007)
Clin Cancer Res
, vol.13
, Issue.4
, pp. 1179-1185
-
-
Righini, C.A.1
De Fraipont, F.2
Timsit, J.F.3
-
203
-
-
37549047612
-
A novel set of DNA methylation markers in urine sediments for sensitive/specific detection of bladder cancer
-
Yu J, Zhu T, Wang Z, et al. A novel set of DNA methylation markers in urine sediments for sensitive/specific detection of bladder cancer. Clin Cancer Res 2007; 13(24):7296-304
-
(2007)
Clin Cancer Res
, vol.13
, Issue.24
, pp. 7296-7304
-
-
Yu, J.1
Zhu, T.2
Wang, Z.3
-
204
-
-
0033577058
-
Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer
-
Ahrendt SA, Chow JT, Xu LH, et al. Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer. J Natl Cancer Inst 1999;91(4):332-9
-
(1999)
J Natl Cancer Inst
, vol.91
, Issue.4
, pp. 332-339
-
-
Ahrendt, S.A.1
Chow, J.T.2
Xu, L.H.3
-
205
-
-
0032578509
-
Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis
-
Belinsky SA, Nikula KJ, Palmisano WA, et al. Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis. Proc Natl Acad Sci USA 1998;95(20):11891-6
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.20
, pp. 11891-11896
-
-
Belinsky, S.A.1
Nikula, K.J.2
Palmisano, W.A.3
-
206
-
-
66349102768
-
Methylation of TFPI2 in stool DNA: A potential novel biomarker for the detection of colorectal cancer
-
Glockner SC, Dhir M, Yi JM, et al. Methylation of TFPI2 in stool DNA: a potential novel biomarker for the detection of colorectal cancer. Cancer Res 2009;69(11):4691-9
-
(2009)
Cancer Res
, vol.69
, Issue.11
, pp. 4691-4699
-
-
Glockner, S.C.1
Dhir, M.2
Yi, J.M.3
-
207
-
-
0042334827
-
Detection of gene promoter hypermethylation in fine needle washings from breast lesions
-
Jeronimo C, Costa I, Martins MC, et al. Detection of gene promoter hypermethylation in fine needle washings from breast lesions. Clin Cancer Res 2003; 9(9):3413-17
-
(2003)
Clin Cancer Res
, vol.9
, Issue.9
, pp. 3413-3417
-
-
Jeronimo, C.1
Costa, I.2
Martins, M.C.3
-
208
-
-
3042729741
-
Detection of lymph node micrometastases by gene promoter hypermethylation in samples obtained by endosonographyguided fine-needle aspiration biopsy
-
Pellise M, Castells A, Gines A, et al. Detection of lymph node micrometastases by gene promoter hypermethylation in samples obtained by endosonographyguided fine-needle aspiration biopsy. Clin Cancer Res 2004;10(13):4444-9
-
(2004)
Clin Cancer Res
, vol.10
, Issue.13
, pp. 4444-4449
-
-
Pellise, M.1
Castells, A.2
Gines, A.3
-
209
-
-
84878242633
-
Methylated DNA and microRNA in body fluids as biomarkers for cancer detection
-
Ma Y, Wang X, Jin H. Methylated DNA and microRNA in body fluids as biomarkers for cancer detection. Int J Mol Sci 2013;14(5):10307-31 .. Reviews the utility of DNA methylation as a biomarker in body fluids.
-
(2013)
Int J Mol Sci
, vol.14
, Issue.5
, pp. 10307-10331
-
-
Ma, Y.1
Wang, X.2
Jin, H.3
-
210
-
-
0035870248
-
A gene hypermethylation profile of human cancer
-
Esteller M, Corn PG, Baylin SB, Herman JG. A gene hypermethylation profile of human cancer. Cancer Res 2001; 61(8):3225-9
-
(2001)
Cancer Res
, vol.61
, Issue.8
, pp. 3225-3229
-
-
Esteller, M.1
Corn, P.G.2
Baylin, S.B.3
Herman, J.G.4
-
211
-
-
84885735554
-
Mutational landscape and significance across 12 major cancer types
-
Kandoth C, McLellan MD, Vandin F, et al. Mutational landscape and significance across 12 major cancer types. Nature 2013; 502(7471):333-9
-
(2013)
Nature
, vol.502
, Issue.7471
, pp. 333-339
-
-
Kandoth, C.1
McLellan, M.D.2
Vandin, F.3
-
212
-
-
84880507665
-
Mutational heterogeneity in cancer and the search for new cancer-associated genes
-
Lawrence MS, Stojanov P, Polak P, et al. Mutational heterogeneity in cancer and the search for new cancer-associated genes. Nature 2013;499(7457):214-18
-
(2013)
Nature
, vol.499
, Issue.7457
, pp. 214-218
-
-
Lawrence, M.S.1
Stojanov, P.2
Polak, P.3
-
213
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
Alexandrov LB, Nik-Zainal S, Wedge DC, et al. Signatures of mutational processes in human cancer. Nature 2013;500(7463): 415-21
-
(2013)
Nature
, vol.500
, Issue.7463
, pp. 415-421
-
-
Alexandrov, L.B.1
Nik-Zainal, S.2
Wedge, D.C.3
-
214
-
-
84924627714
-
Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer
-
Brocks D, Assenov Y, Minner S, et al. Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer. Cell Rep 2014;8(3):798-806
-
(2014)
Cell Rep
, vol.8
, Issue.3
, pp. 798-806
-
-
Brocks, D.1
Assenov, Y.2
Minner, S.3
-
215
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
Gerlinger M, Rowan AJ, Horswell S, et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 2012;366(10): 883-92
-
(2012)
N Engl J Med
, vol.366
, Issue.10
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
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