Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer

Journal of the National Cancer Institute

Volumn 91, Issue 4, 1999, Pages 332-339

  Ahrendt, Steven A ^b   Chow, John T ^a   Xu, Li Hua ^a   Yang, Stephen C ^a   Eisenberger, Claus F ^a   Esteller, Manel ^a   Herman, James G ^a   Wu, Li ^a   Decker, Anthony ^b   Jen, Jin ^a   Sidransky, David ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PROTEIN P16; PROTEIN P53;

ARTICLE; CANCER DIAGNOSIS; CANCER STAGING; CPG ISLAND; CYTOLOGY; DNA METHYLATION; EARLY CANCER; GENE MUTATION; HUMAN; HUMAN CELL; LUNG LAVAGE; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MICROSATELLITE INSTABILITY; ONCOGENE K RAS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TUMOR CELL; TUMOR SUPPRESSOR GENE;

EID: 0033577058     PISSN: 00278874     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnci/91.4.332     Document Type: Article

References (35)

1. Landis SH, Murray T, Bolden A, Wingo PA. Cancer statistics, 1998 [published erratum appears in CA Cancer J Clin 1998;48:192]. CA Cancer J Clin 1998;48:6-29.
2. Landis SH, Murray T, Bolden A, Wingo PA. Cancer statistics, 1998 [published erratum appears in CA Cancer J Clin 1998;48:192]. CA Cancer J Clin 1998;48:6-29.
3. Naruke T, Goya T, Tsuchiya R, Suemasu K. Prognosis and survival in resected lung carcinoma based on the new international staging system [published erratum appears in J Thorac Cardiovasc Surg 1989;97:350]. J Thorac Cardiovasc Surg 1988;96:440-7
4. Naruke T, Goya T, Tsuchiya R, Suemasu K. Prognosis and survival in resected lung carcinoma based on the new international staging system [published erratum appears in J Thorac Cardiovasc Surg 1989;97:350]. J Thorac Cardiovasc Surg 1988;96:440-7
5. Berlin NI, Buncher CR, Fontana RS, Frost JK, Melamed MR. The National Cancer Institute Cooperative Early Lung Cancer Detection Program. Results of the initial screen (prevalence). Early lung cancer detection: introduction. Am Rev Respir Dis 1984;130:545-9.
6. Tockman MS. Survival and mortality from lung cancer in a screened population. Chest 1986;89:324S-325S.
7. Mao L, Hruban RH, Boyle JO, Tockman M, Sidransky D. Detection of oncogene mutations in sputum precedes diagnosis of lung cancer. Cancer Res 1994;54:1634-7.
8. Mountain CF. Revisions in the International System for Staging Lung Cancer. Chest 1997;111:1710-7.
9. Brennan JA, Mao L, Hruban RH, Boyle JO, Eby YJ, Koch WM, et al. Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck. N Engl J Med 1995;332:429-35.
10. Boyle JO, Hakim J, Koch W, van der Riet P, Hruban RH, Roa A, et al. The incidence of p53 mutations increases with progression of head and neck cancer. Cancer Res 1993;53:4477-80.
11. Ahrendt SA, Yang SC, Wu L, Westra WH, Jen J, Califano JC, et al. Comparison of oncogene mutation detection and telomerase activity for the molecular staging of non-small cell lung cancer. Clin Cancer Res 1997;3: 1207-14.
12. Rodenhuis S, Slebos RJ. Clinical significance of ras oncogene activation in human lung cancer. Cancer Res 1992;52 (9 Suppl):2665s-2669s.
13. Jen J, Powell SM, Papadopoulos N, Smith KJ, Hamilton SR, Vogelstein B, et al. Molecular determinants of dysplasia in colorectal lesions. Cancer Res 1994;54:5523-6.
14. Yakubovskaya MS, Spiegelman V, Luo FC, Malaev S, Salnev A, Zborovskaya I, et al. High frequency of K-ras mutations in normal appearing lung tissues and sputum of patients with lung cancer. Int J Cancer 1995;63: 810-4.
15. Mills NE, Fishman CL, Scholes J, Anderson SE, Rom WN, Jacobson DR. Detection of K-ras oncogene mutations in bronchoalveolar lavage fluid for lung cancer diagnosis [published erratum appears in J Natl Cancer Inst 1995;87:1643]. J Natl Cancer Inst 1995;87:1056-60.
16. Mills NE, Fishman CL, Scholes J, Anderson SE, Rom WN, Jacobson DR. Detection of K-ras oncogene mutations in bronchoalveolar lavage fluid for lung cancer diagnosis [published erratum appears in J Natl Cancer Inst 1995;87:1643]. J Natl Cancer Inst 1995;87:1056-60.
17. Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci U S A 1996;93:9821-6.
18. Miozzo M, Sozzi G, Musso K, Pilotti S, Incarbone M, Pastorino U, et al. Microsatellite alterations in bronchial and sputum specimens of lung cancer patients. Cancer Res 1996;56:2285-8.
19. Mao L, Lee DJ, Tockman MS, Erozan YS, Askin F, Sidransky D. Microsatellite alterations as clonal markers for the detection of human cancer. Proc Natl Acad Sci U S A 1994;91:9871-5.
20. Strauss GM, Gleason RE, Sugarbaker DJ. Screening for lung cancer. Another look; a different view. Chest 1997;111:754-68.
21. Frost JK, Ball WC Jr, Levin ML, Tockman MS, Baker RR, Carter D, et al. Early lung cancer detection: results of the initial (prevalence) radiologic and cytologic screening in the Johns Hopkins study. Am Rev Respir Dis 1984;1:549-54.
22. Bechtel JJ, Kelley WR, Petty TL, Patz DS, Saccomanno G. Outcome of 51 patients with roentgenographically occult lung cancer detected by sputum cytologic testing; a community hospital program [published erratum appears in Arch Intern Med 1994;154:1582]. Arch Intern Med 1994;154: 975-80.
23. Bechtel JJ, Kelley WR, Petty TL, Patz DS, Saccomanno G. Outcome of 51 patients with roentgenographically occult lung cancer detected by sputum cytologic testing; a community hospital program [published erratum appears in Arch Intern Med 1994;154:1582]. Arch Intern Med 1994;154: 975-80.
24. de Gracia J, Bravo C, Miravitlles M, Tallada N, Orriols R, Bellmunt J, et al. Diagnostic value of bronchoalveolar lavage in peripheral lung cancer. Am Rev Respir Dis 1993;147:649-52.
25. Poletti V, Romagna M, Allen KA, Gasponi A, Spiga L. Bronchoalveolar lavage in the diagnosis of disseminated lung tumors. Acta Cytol 1995;39: 472-7.
26. (22; Payne PW, Sebo TJ, Doudkine A, Garner D, MacAulay C, Lam S, et al. Sputum screening by quantitative microscopy: a reexamination of a portion of the National Cancer Institute Cooperative Early Lung Cancer Study. Mayo Clin Proc 1997;72:697-704.
27. Qiao YL, Tockman MS, Li L, Erozan YS, Yao SX, Barrett MJ, et al. A case-cohort study of an early biomarker of lung cancer in a screening cohort of Yunnan tin miners in China. Cancer Epidemiol Biomarkers Prev 1997;6:893-900.
28. Sidransky D, Tokino T, Hamilton SR, Kinzler KW, Levin B, Frost P, et al. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science 1992;256:102-5.
29. Mao L, Schoenberg MP, Scicchitano M, Erozan YS, Merlo A, Schwab D, el al. Molecular detection of primary bladder cancer by microsatellite analysis. Science 1996;271:659-62.
30. Nawroz H, Koch W, Anker P, Stroun M, Sidransky D. Microsatellite alterations in serum DNA of head and neck cancer patients. Nat Med 1996;2:1035-7.
31. Shridhar V, Siegfried J, Hunt J, del Mar Alonso M, Smith DI. Genetic instability of microsatellite sequences in many non-small cell lung carcinomas. Cancer Res 1994;54:2084-7.
32. Fong KM, Zimmerman PV, Smith PJ. Microsatellite instability and other molecular abnormalities in non-small cell lung cancer. Cancer Res 1995; 55:28-30.
33. Peltomaki P, Lothe RA, Aaltonen LA, Pylkkanen L, Nystrom-Lahti M, Seruca R, et al. Microsatellite instability is associated with tumors that characterize the hereditary non-polyposis colorectal carcinoma syndrome. Cancer Res 1993;53:5853-5.
34. Liggett WH Jr, Sidransky D. Role of the p16 tumor suppressor gene in cancer. J Clin Oncol 1998;16:1197-206.
35. INK4a is an early event in lung cancer and a potential biomarker for early diagnosis. Proc Natl Acad Sci USA 1998;95:11891-6.