Molecular dynamics study of the recognition of dimethylated CpG sites by MBD1 protein

Journal of Chemical Information and Modeling

Volumn 55, Issue 3, 2015, Pages 636-644

  Bianchi, Caterina ^a   Zangi, Ronen ^a,b  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b BASQUE FOUNDATION FOR SCIENCE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; BINDING ENERGY; CONFORMATIONS; DNA; FREE ENERGY; HYDROGEN BONDS; HYDROPHOBICITY; MACHINERY; MOLECULAR DYNAMICS; PROTEINS;

BINDING AFFINITIES; CONFORMATIONAL CHANGE; CONSERVED RESIDUES; DNA-PROTEIN INTERACTION; HYDROPHOBIC RESIDUES; METHYL-CPG-BINDING; MOLECULAR DYNAMICS SIMULATIONS; PROTEIN-DNA INTERFACE;

BINDING SITES;

CYTOSINE; DNA BINDING PROTEIN; MBD1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TYROSINE;

BINDING SITE; CHEMICAL PHENOMENA; CHEMISTRY; CPG ISLAND; DNA METHYLATION; GENETICS; HUMAN; HYDROGEN BOND; METABOLISM; MOLECULAR DYNAMICS; PHYSIOLOGY; PROTEIN CONFORMATION;

BINDING SITES; CPG ISLANDS; CYTOSINE; DNA METHYLATION; DNA-BINDING PROTEINS; HUMANS; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MOLECULAR DYNAMICS SIMULATION; PROTEIN CONFORMATION; TRANSCRIPTION FACTORS; TYROSINE;

EID: 84925440397     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci500657d     Document Type: Article

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