-
2
-
-
0034050902
-
Systematic variation in gene expression patterns in human cancer cell lines
-
(2000)
Nat. Genet.
, vol.24
, pp. 227-235
-
-
Ross, D.T.1
Scherf, U.2
Eisen, M.B.3
Perou, C.M.4
Rees, C.5
Spellman, P.6
Iyer, V.7
Jeffrey, S.S.8
Van de Rijn, M.9
Waltham, M.10
Pergamenschikov, A.11
Lee, J.C.12
Lashkari, D.13
Shalon, D.14
Myers, T.G.15
Weinstein, J.N.16
Botstein, D.17
Brown, P.O.18
-
5
-
-
0343621494
-
Aberrant CpG-island methylation has nonrandom and tumour-type-specific patterns
-
(2000)
Nat. Genet.
, vol.24
, pp. 132-138
-
-
Costello, J.E.1
Fruhwald, M.C.2
Smiraglia, D.J.3
Rush, L.J.4
Robertson, G.P.5
Gao, X.6
Wright, F.A.7
Feramisco, J.D.8
Peltomaki, P.9
Lang, J.C.10
Schuller, D.E.11
Yu, L.12
Bloomfield, C.D.13
Caligiuri, M.A.14
Yates, A.15
Nishikawa, R.16
Su Huang, H.17
Petrelli, N.J.18
Zhang, X.19
O'Dorisio, M.S.20
Held, W.A.21
Cavenee, W.K.22
Plass, C.23
more..
-
7
-
-
0029011539
-
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
-
(1995)
Nat. Med.
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, D.J.4
Gabrielson, E.5
Burger, P.C.6
Baylin, S.B.7
Sidransky, D.8
-
8
-
-
0028845142
-
Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
-
(1995)
Cancer Res.
, vol.55
, pp. 4525-4530
-
-
Herman, J.G.1
Merlo, A.2
Mao, L.3
Lapidus, R.G.4
Issa, J.P.5
Davidson, N.E.6
Sidransky, D.7
Baylin, S.B.8
-
10
-
-
0034194330
-
Progressive increases in de novo methylation of CpG islands in bladder cancer
-
(2000)
Cancer Res.
, vol.60
, pp. 2473-2476
-
-
Salem, C.1
Liang, G.2
Tsai, Y.C.3
Coulter, J.4
Knowles, M.A.5
Feng, A.C.6
Groshen, S.7
Nichols, P.W.8
Jones, P.A.9
-
12
-
-
0030697181
-
Low frequency of p16/CDKN2A methylation in sporadic melanoma: Comparative approaches for methylation analysis of primary tumors
-
(1997)
Cancer Res.
, vol.57
, pp. 5336-5347
-
-
Gonzalgo, M.L.1
Bender, C.M.2
You, E.H.3
Glendening, J.M.4
Flores, J.F.5
Walker, G.J.6
Hayward, N.K.7
Jones, P.A.8
Fountain, J.W.9
-
15
-
-
19244370208
-
6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis
-
(2000)
Cancer Res.
, vol.60
, pp. 2368-2371
-
-
Esteller, M.1
Toyota, M.2
Sanchez-Cespedes, M.3
Capella, G.4
Peinado, M.A.5
Watkins, D.N.6
Issa, J.P.7
Sidransky, D.8
Baylin, S.B.9
Herman, J.G.10
-
17
-
-
0034652596
-
Gene promoter hypermethylation in tumors and serum of head and neck cancer patients
-
(2000)
Cancer Res.
, vol.60
, pp. 892-895
-
-
Sanchez-Cespedes, M.1
Esteller, M.2
Wu, L.3
Nawroz-Danish, H.4
Yoo, G.H.5
Koch, W.M.6
Jen, J.7
Herman, J.G.8
Sidransky, D.9
-
19
-
-
0034662626
-
Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer
-
(2000)
Cancer Res.
, vol.60
, pp. 4366-4371
-
-
Esteller, M.1
Sparks, A.2
Toyota, M.3
Sanchez-Cespedes, M.4
Capella, G.5
Peinado, M.A.6
Gonzalez, S.7
Tarafa, G.8
Sidransky, D.9
Meltzer, S.J.10
Baylin, S.B.11
Herman, J.G.12
-
21
-
-
0028152397
-
Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 11733-11737
-
-
Lee, W.H.1
Morton, R.A.2
Epstein, J.I.3
Brooks, J.D.4
Campbell, P.A.5
Bova, G.S.6
Hsieh, W.S.7
Isaacs, W.B.8
Nelson, W.G.9
-
23
-
-
0030887086
-
Hypermethylation of the APC (adenomatous polyposis coli) gene promoter region in human colorectal carcinoma
-
(1997)
Int. J. Cancer
, vol.70
, pp. 644-648
-
-
Hiltunen, M.O.1
Alhonen, L.2
Koistinaho, J.3
Myohanen, S.4
Paakkonen, M.5
Marin, S.6
Kosma, V.M.7
Janne, J.8
-
25
-
-
0030757685
-
DAP-kinase loss of expression in various carcinoma and B-cell lymphoma cell lines: Possible implications for role as tumor suppressor gene
-
(1997)
Oncogene
, vol.15
, pp. 403-407
-
-
Kissil, J.L.1
Feinstein, E.2
Cohen, O.3
Jones, P.A.4
Tsai, Y.C.5
Knowles, M.A.6
Eydmann, M.E.7
Kimchi, A.8
-
26
-
-
18844482200
-
GSTP1 CpG island DNA hypermethylation in hepatocellular carcinomas
-
(2000)
Int. J. Oncol.
, vol.16
, pp. 663-676
-
-
Tchou, J.C.1
Lin, X.2
Freije, D.3
Isaacs, W.B.4
Brooks, J.D.5
Rashid, A.6
De Matzo, A.M.7
Kanai, Y.8
Hirohashi, S.9
Nelson, W.G.10
-
27
-
-
0034607234
-
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors
-
(2000)
J. Natl. Cancer Inst.
, vol.92
, pp. 564-569
-
-
Esteller, M.1
Silva, J.M.2
Dominguez, G.3
Bonilla, F.4
Matias-Guiu, X.5
Lerma, E.6
Bussaglia, E.7
Prat, J.8
Harkes, I.C.9
Repasky, E.A.10
Gabrielson, E.11
Schutte, M.12
Baylin, S.B.13
Herman, J.G.14
-
29
-
-
0031017268
-
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines
-
(1997)
Cancer Res.
, vol.57
, pp. 808-811
-
-
Kane, M.F.1
Loda, M.2
Gaida, G.M.3
Lipman, J.4
Mishra, R.5
Goldman, H.6
Jessup, J.M.7
Kolodner, R.8
-
30
-
-
13144266670
-
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6870-6875
-
-
Herman, J.G.1
Umar, A.2
Polyak, K.3
Graff, J.R.4
Ahuja, N.5
Issa, J.P.6
Markowitz, S.7
Willson, J.K.8
Hamilton, S.R.9
Kinzler, K.W.10
Kane, M.F.11
Kolodner, R.D.12
Vogelstein, B.13
Kunkel, T.A.14
Baylin, S.B.15
-
32
-
-
0033105363
-
Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability
-
(2000)
Cancer Res.
, vol.59
, pp. 1090-1095
-
-
Fleisher, A.S.1
Esteller, M.2
Wang, S.3
Tamura, G.4
Suzuki, H.5
Yin, J.6
Zou, T.T.7
Abraham, J.M.8
Kong, D.9
Smolinski, K.N.10
Shi, Y.Q.11
Rhyu, M.G.12
Powell, S.M.13
James, S.P.14
Wilson, K.T.15
Herman, J.G.16
Meltzer, S.J.17
-
34
-
-
0033179665
-
Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation
-
(1999)
Blood
, vol.94
, pp. 1113-1120
-
-
Kawano, S.1
Miller, C.W.2
Gombart, A.F.3
Bartram, C.R.4
Matsuo, Y.5
Asou, H.6
Sakashita, A.7
Said, J.8
Tatsumi, E.9
Koeffler, H.P.10
-
37
-
-
0034654269
-
Aberrant p15 promoter methylation in adult and childhood acute leukemias of nearly all morphologic subtypes: Potential prognostic implications
-
(2000)
Blood
, vol.95
, pp. 1942-1949
-
-
Wong, I.H.1
Ng, M.H.2
Huang, D.P.3
Lee, J.C.4
-
39
-
-
0034665332
-
Fields of aberrant CpG island hypermethylation in Barrett's esophagus and associated adenocarcinoma
-
(2000)
Cancer Res.
, vol.60
, pp. 5021-5026
-
-
Eads, C.A.1
Lord, R.V.2
Kurumboor, S.K.3
Wickramasinghe, K.4
Skinner, M.L.5
Long, T.I.6
Peters, J.H.7
DeMeester, T.R.8
Danenberg, K.D.9
Danenberg, P.V.10
Laird, P.W.11
Skinner, K.A.12
-
40
-
-
0033229890
-
Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype
-
(1999)
Cancer Res.
, vol.59
, pp. 5438-5442
-
-
Toyota, M.1
Ahuja, N.2
Suzuki, H.3
Itoh, F.4
Ohe-Toyota, M.5
Imai, K.6
Baylin, S.B.7
Issa, J.P.8
-
43
-
-
0031771497
-
The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6457-6473
-
-
Robertson, K.D.1
Jones, P.A.2
-
44
-
-
0032578509
-
INK4a is an early event in lung cancer and a potential biomarker for early diagnosis
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 11891-11896
-
-
Belinsky, S.A.1
Nikula, K.J.2
Palmisano, W.A.3
Michels, R.4
Saccomanno, G.5
Gabrielson, E.6
Baylin, S.B.7
Herman, J.G.8
-
46
-
-
0034282793
-
Microsatellite instability in inflammatory bowel disease-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, hMLH1
-
(2000)
Cancer Res.
, vol.60
, pp. 4864-4868
-
-
Fleisher, A.S.1
Esteller, M.2
Harpaz, N.3
Leytin, A.4
Rashid, A.5
Xu, Y.6
Liang, J.7
Stine, O.C.8
Yin, J.9
Zou, T.T.10
Abraham, J.M.11
Kong, D.12
Wilson, K.T.13
James, S.P.14
Herman, J.G.15
Meltzer, S.J.16
-
48
-
-
0033563165
-
Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification
-
(1999)
Cancer Res.
, vol.59
, pp. 2307-2312
-
-
Toyota, M.1
Ho, C.2
Ahuja, N.3
Jair, K.W.4
Li, Q.5
Ohe-Toyota, M.6
Baylin, S.B.7
Issa, J.P.8
-
49
-
-
0027316298
-
Restriction landmark genomic scanning method and its various applications
-
(1993)
Electrophoresis
, vol.14
, pp. 251-258
-
-
Hayashizaki, Y.1
Hirotsune, S.2
Okazaki, Y.3
Hatada, I.4
Shibata, H.5
Kawai, J.6
Hirose, K.7
Watanabe, S.8
Fushiki, S.9
Wada, S.10
-
52
-
-
0033676843
-
TMS1, a novel proapoptotic caspase recruitment domain protein, is a target of methylation-induced gene silencing in human breast cancers
-
(2000)
Cancer Res.
, vol.60
, pp. 6236-6242
-
-
Conway, K.E.1
McConnell, B.B.2
Bowring, C.E.3
Donald, C.D.4
Warren, S.T.5
Vertino, P.M.6
-
54
-
-
0034626988
-
Inactivation of the DNA repair gene MGMT and the clinical response of gliomas to alkylating agents
-
(2000)
N. Engl. J. Med.
, vol.343
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
Goodman, S.N.4
Hidalgo, O.F.5
Vanaclocha, V.6
Baylin, S.B.7
Herman, J.G.8
-
56
-
-
0028106016
-
Glutathione-associated enzymes in anticancer drug resistance
-
(1994)
Cancer Res.
, vol.54
, pp. 4313-4320
-
-
Tew, K.D.1
|