-
1
-
-
35348964557
-
Advances in radiation therapy for brain tumors
-
Stieber VW, Mehta MP. Advances in radiation therapy for brain tumors. Neurol Clin. 2007;25:1005-1033.
-
(2007)
Neurol Clin
, vol.25
, pp. 1005-1033
-
-
Stieber, V.W.1
Mehta, M.P.2
-
2
-
-
0037384037
-
A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma
-
Westphal M, Hilt DC, Bortey E, et al. A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma. Neuro Oncol. 2003;5:79-88.
-
(2003)
Neuro Oncol
, vol.5
, pp. 79-88
-
-
Westphal, M.1
Hilt, D.C.2
Bortey, E.3
-
3
-
-
0028917333
-
Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group
-
Brem H, Piantadosi S, Burger PC, et al. Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. The Polymer-brain Tumor Treatment Group. Lancet. 1995;345:1008-1012.
-
(1995)
Lancet
, vol.345
, pp. 1008-1012
-
-
Brem, H.1
Piantadosi, S.2
Burger, P.C.3
-
4
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352:987-996.
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
-
5
-
-
41649112610
-
Bevacizumab for recurrent malignant gliomas: Efficacy, toxicity, and patterns of recurrence
-
Norden AD, Young GS, Setayesh K, et al. Bevacizumab for recurrent malignant gliomas: efficacy, toxicity, and patterns of recurrence. Neurology. 2008;70:779-787.
-
(2008)
Neurology
, vol.70
, pp. 779-787
-
-
Norden, A.D.1
Young, G.S.2
Setayesh, K.3
-
6
-
-
65649097691
-
Molecular advances of brain tumors in radiation oncology
-
Noda SE, El-Jawahri A, Patel D, Lautenschlaeger T, Siedow M, Chakravarti A. Molecular advances of brain tumors in radiation oncology. Semin Radiat Oncol. 2009;19:171-178.
-
(2009)
Semin Radiat Oncol
, vol.19
, pp. 171-178
-
-
Noda, S.E.1
El-Jawahri, A.2
Patel, D.3
Lautenschlaeger, T.4
Siedow, M.5
Chakravarti, A.6
-
7
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens AC, Gorlia T, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med. 2005;352:997-1003.
-
(2005)
N Engl J Med
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
-
8
-
-
60649106195
-
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
-
Paez-Ribes M, Allen E, Hudock J, et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell. 2009;15:220-231.
-
(2009)
Cancer Cell
, vol.15
, pp. 220-231
-
-
Paez-Ribes, M.1
Allen, E.2
Hudock, J.3
-
9
-
-
68649120407
-
Recurrence pattern in glioblastoma multiforme patients treated with anti-angiogenic chemotherapy
-
Tuettenberg J, Grobholz R, Seiz M, et al. Recurrence pattern in glioblastoma multiforme patients treated with anti-angiogenic chemotherapy. J Cancer Res Clin Oncol. 2009;135:1239-1244.
-
(2009)
J Cancer Res Clin Oncol
, vol.135
, pp. 1239-1244
-
-
Tuettenberg, J.1
Grobholz, R.2
Seiz, M.3
-
10
-
-
34447285771
-
Prognostic factors for survival in adult patients with recurrent glioma enrolled onto the new approaches to brain tumor therapy CNS consortium phase I and II clinical trials
-
Carson KA, Grossman SA, Fisher JD, Shaw EG. Prognostic factors for survival in adult patients with recurrent glioma enrolled onto the new approaches to brain tumor therapy CNS consortium phase I and II clinical trials. J Clin Oncol. 2007;25: 2601-2606.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2601-2606
-
-
Carson, K.A.1
Grossman, S.A.2
Fisher, J.D.3
Shaw, E.G.4
-
11
-
-
77953669101
-
Transcription profiling of brain tumors: Tumor biology and treatment stratification
-
In: Van Meir EG, ed
-
Sulman EP, Guerrero M, Aldape K. Transcription profiling of brain tumors: tumor biology and treatment stratification. In: Van Meir EG, ed. CNS Cancer: Models, Markers, Prognostic Factors, Targets and TherapeuticApproaches.1sted.NewYork: Humana Press (Springer); 2009:529-552.
-
(2009)
CNS Cancer: Models, Markers, Prognostic Factors, Targets and TherapeuticApproaches.1sted.NewYork: Humana Press (Springer)
, pp. 529-552
-
-
Sulman, E.P.1
Guerrero, M.2
Aldape, K.3
-
12
-
-
69949107753
-
The role of vascular endothelial growth factor genetic variability in cancer
-
Schneider BP, Radovich M, Miller KD. The role of vascular endothelial growth factor genetic variability in cancer. Clin Cancer Res. 2009;15:5297-5302.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5297-5302
-
-
Schneider, B.P.1
Radovich, M.2
Miller, K.D.3
-
13
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
The Cancer Genome Atlas Research Network
-
The Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature. 2008;455: 1061-1068.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
14
-
-
70449099233
-
Brain cancer propagating cells: Biology, genetics and targeted therapies
-
Hadjipanayis CG, Van Meir EG. Brain cancer propagating cells: biology, genetics and targeted therapies. Trends Mol Med. 2009;14:519-530.
-
(2009)
Trends Mol Med
, vol.14
, pp. 519-530
-
-
Hadjipanayis, C.G.1
van Meir, E.G.2
-
15
-
-
64149101418
-
Tumor initiating cells in malignant gliomas: Biology and implications for therapy
-
Hadjipanayis CG, Van Meir EG. Tumor initiating cells in malignant gliomas: biology and implications for therapy. J Mol Med. 2009;87:363-374.
-
(2009)
J Mol Med
, vol.87
, pp. 363-374
-
-
Hadjipanayis, C.G.1
van Meir, E.G.2
-
16
-
-
19044397160
-
EpidermalgrowthfactorreceptorandInk4a/ Arf: Convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
-
Bachoo RM, Maher EA, Ligon KL, et al. EpidermalgrowthfactorreceptorandInk4a/ Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell. 2002;1:269-277.
-
(2002)
Cancer Cell
, vol.1
, pp. 269-277
-
-
Bachoo, R.M.1
Maher, E.A.2
Ligon, K.L.3
-
17
-
-
2342588221
-
Vaso-occlusive and prothrombotic mechanisms associated with tumor hypoxia, necrosis, and accelerated growth in glioblastoma
-
Brat DJ, Van Meir EG. Vaso-occlusive and prothrombotic mechanisms associated with tumor hypoxia, necrosis, and accelerated growth in glioblastoma. Lab Invest. 2004;84:397-405.
-
(2004)
Lab Invest
, vol.84
, pp. 397-405
-
-
Brat, D.J.1
van Meir, E.G.2
-
18
-
-
0021932240
-
Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin
-
Libermann TA, Nusbaum HR, Razon N, et al. Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin. Nature. 1985;313:144-147.
-
(1985)
Nature
, vol.313
, pp. 144-147
-
-
Libermann, T.A.1
Nusbaum, H.R.2
Razon, N.3
-
19
-
-
0010645263
-
Mitotic recombination of chromosome 17 in astrocytomas
-
James CD, Carlbom E, Nordenskjold M, Collins VP, Cavenee WK. Mitotic recombination of chromosome 17 in astrocytomas. Proc Natl Acad Sc i U S A. 1989;86:2858-2862.
-
(1989)
Proc Natl Acad Sc I U S A
, vol.86
, pp. 2858-2862
-
-
James, C.D.1
Carlbom, E.2
Nordenskjold, M.3
Collins, V.P.4
Cavenee, W.K.5
-
20
-
-
77953656686
-
Van Meir EG. p53 pathway alterations in brain tumors
-
New York: Humana Press (Springer)
-
Yin S, Van Meir EG. p53 pathway alterations in brain tumors. In: Van Meir EG, ed. CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st ed. New York: Humana Press (Springer); 2009:283-314.
-
(2009)
CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st Ed
, pp. 283-314
-
-
Yin, S.1
van Meir, E.G.2
-
21
-
-
77953680275
-
The PTEN/PI3 kinase pathway in human glioma
-
In: Van Meir EG, ed., New York: Humana Press (Springer)
-
Stokoe D, Furnari FB. The PTEN/PI3 kinase pathway in human glioma. In: Van Meir EG, ed. CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st ed. New York: Humana Press (Springer); 2009:315-357.
-
(2009)
CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st Ed
, pp. 315-357
-
-
Stokoe, D.1
Furnari, F.B.2
-
22
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons DW, Jones S, Zhang X, et al. An integrated genomic analysis of human glioblastoma multiforme. Science. 2008; 321:1807-1812.
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
-
23
-
-
64849098267
-
Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF1alpha
-
Zhao S, Lin Y, Xu W, et al. Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF1alpha. Science. 2009;324:261-265.
-
(2009)
Science
, vol.324
, pp. 261-265
-
-
Zhao, S.1
Lin, Y.2
Xu, W.3
-
25
-
-
72049125350
-
Cancerassociated IDH1 mutations produce 2-hy droxyglutarate
-
Dang L, White DW, Gross S, et al. Cancerassociated IDH1 mutations produce 2-hy droxyglutarate. Nature. 2009;462:739-744.
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
-
27
-
-
73649123907
-
An integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR and NF1
-
Verhaak RGW, Hoadley KA, Purdom E, et al. An integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR and NF1. Cancer Cell. 2010;17:98-110.
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.W.1
Hoadley, K.A.2
Purdom, E.3
-
28
-
-
48249125791
-
Malignant gliomas in adults
-
Wen PY, Kesari S. Malignant gliomas in adults. N Engl J Med. 2008;359:492-507.
-
(2008)
N Engl J Med
, vol.359
, pp. 492-507
-
-
Wen, P.Y.1
Kesari, S.2
-
29
-
-
84880840663
-
Clinical agents for the targeting of brain tumor vasculature
-
In: Van Meir EG, ed., New York: Humana Press (Springer)
-
Gerstner ER, Batchelor TT. Clinical agents for the targeting of brain tumor vasculature. In: Van Meir EG, ed. CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st ed. New York: Humana Press (Springer); 2009:731-728.
-
(2009)
CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st Ed
, pp. 731-728
-
-
Gerstner, E.R.1
Batchelor, T.T.2
-
30
-
-
54549095950
-
Yan H, et al. p53 and Pten control neural and glioma stem/ progenitor cell renewal and differentiation
-
Zheng H, Ying H, Yan H, et al. p53 and Pten control neural and glioma stem/ progenitor cell renewal and differentiation. Nature. 2008;455:1129-1133.
-
(2008)
Nature
, vol.455
, pp. 1129-1133
-
-
Zheng, H.1
Ying, H.2
-
31
-
-
77953654741
-
Targeting of TRAIL apoptotic pathways for glioblastoma therapies
-
In: Van Meir EG, ed., New York: Humana Press (Springer)
-
Bellail AC, Mulligan P, Hao C. Targeting of TRAIL apoptotic pathways for glioblastoma therapies. In: Van Meir EG, ed. CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st ed. New York: Humana Press (Springer); 2009:977-1010.
-
(2009)
CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st Ed
, pp. 977-1010
-
-
Bellail, A.C.1
Mulligan, P.2
Hao, C.3
-
32
-
-
33646751692
-
Genomic alterations in human malignant glioma cells associate with the cell resistance to the combination treatment with tumor necrosis factor-related apoptosis-inducing ligand and chemotherapy
-
Li YC, Tzeng CC, Song JH, et al. Genomic alterations in human malignant glioma cells associate with the cell resistance to the combination treatment with tumor necrosis factor-related apoptosis-inducing ligand and chemotherapy. Clin Cancer Res. 2006;12:2716-2729.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2716-2729
-
-
Li, Y.C.1
Tzeng, C.C.2
Song, J.H.3
-
33
-
-
77953671248
-
The NF-kB signaling pathway in GBMs: Implications for apoptotic and inflammatory responses and exploitation for therapy
-
In: Van Meir EG, ed
-
Laver T, Nozell S, Benveniste EN. The NF-kB signaling pathway in GBMs: implications for apoptotic and inflammatory responses and exploitation for therapy. In: Van Meir EG, ed. CNS Cancer: Models, Markers, Prognostic Factors, Targets and TherapeuticApproaches.1sted.NewYork: Humana Press (Springer); 2009:1011-1036.
-
(2009)
CNS Cancer: Models, Markers, Prognostic Factors, Targets and TherapeuticApproaches.1sted.NewYork: Humana Press (Springer)
, pp. 1011-1036
-
-
Laver, T.1
Nozell, S.2
Benveniste, E.N.3
-
34
-
-
77953681125
-
Aberrant EGFR signaling in glioma
-
In: Van Meir EG, ed., New York: Humana Press (Springer)
-
Hwang Y, Latha K, Gururaj A, Rojas M, Bogler O. Aberrant EGFR signaling in glioma. In: Van Meir EG, ed. CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st ed. New York: Humana Press (Springer); 2009:441-459.
-
(2009)
CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st Ed
, pp. 441-459
-
-
Hwang, Y.1
Latha, K.2
Gururaj, A.3
Rojas, M.4
Bogler, O.5
-
35
-
-
71349088046
-
A phase I/II trial of GW572016 (lapatinib) in recurrent glioblastoma multiforme: Clinical outcomes, pharmacokinetics and molecular correlation
-
Thiessen B, Stewart C, Tsao M, et al. A phase I/II trial of GW572016 (lapatinib) in recurrent glioblastoma multiforme: clinical outcomes, pharmacokinetics and molecular correlation. Cancer Chemother Pharmacol. 2010;65:353-361.
-
(2010)
Cancer Chemother Pharmacol
, vol.65
, pp. 353-361
-
-
Thiessen, B.1
Stewart, C.2
Tsao, M.3
-
36
-
-
69849112085
-
Stratified phase II trial of cetuximab in patients with recurrent high-grade glioma
-
Neyns B, Sadones J, Joosens E, et al. Stratified phase II trial of cetuximab in patients with recurrent high-grade glioma. Ann Oncol. 2009;20:1596-1603.
-
(2009)
Ann Oncol
, vol.20
, pp. 1596-1603
-
-
Neyns, B.1
Sadones, J.2
Joosens, E.3
-
37
-
-
27744606737
-
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
-
Mellinghoff IK, Wang MY, Vivanco I, et al. Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. N Engl J Med. 2005;353:2012-2024.
-
(2005)
N Engl J Med
, vol.353
, pp. 2012-2024
-
-
Mellinghoff, I.K.1
Wang, M.Y.2
Vivanco, I.3
-
38
-
-
21444450373
-
Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib
-
Haas-Kogan DA, Prados MD, Tihan T, et al. Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib. J Natl Cancer Inst. 2005;97:880-887.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 880-887
-
-
Haas-Kogan, D.A.1
Prados, M.D.2
Tihan, T.3
-
39
-
-
62449150719
-
Randomized phase II trial of erlotinib versus temozolomide or carmustine in recurrent glioblastoma: EORTC brain tumor group study 26034
-
van den Bent MJ, Brandes AA, Rampling R, et al. Randomized phase II trial of erlotinib versus temozolomide or carmustine in recurrent glioblastoma: EORTC brain tumor group study 26034. J Clin Oncol. 2009;27:1268-1274.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1268-1274
-
-
van den Bent, M.J.1
Brandes, A.A.2
Rampling, R.3
-
40
-
-
77953674782
-
Modeling gliomas using PDGF-expressing retroviruses
-
In: Van Meir EG, ed., New York: Humana Press (Springer)
-
Assanah M, Lopez KA, Bruce JN, Canoll P. Modeling gliomas using PDGF-expressing retroviruses. In: Van Meir EG, ed. CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st ed. New York: Humana Press (Springer); 2009:3-27.
-
(2009)
CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st Ed
, pp. 3-27
-
-
Assanah, M.1
Lopez, K.A.2
Bruce, J.N.3
Canoll, P.4
-
41
-
-
0034665138
-
Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class
-
Kilic T, Alberta JA, Zdunek PR, et al. Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class. Cancer Res. 2000;60:5143-5150.
-
(2000)
Cancer Res
, vol.60
, pp. 5143-5150
-
-
Kilic, T.1
Alberta, J.A.2
Zdunek, P.R.3
-
42
-
-
33748376520
-
Phase I/II study of imatinib mesylate for recurrentmalignantgliomas:NorthAmerican Brain Tumor Consortium Study 99-08
-
Wen PY, Yung WK, Lamborn KR, et al. Phase I/II study of imatinib mesylate for recurrentmalignantgliomas:NorthAmerican Brain Tumor Consortium Study 99-08. Clin Cancer Res. 2006;12:4899-4907.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 4899-4907
-
-
Wen, P.Y.1
Yung, W.K.2
Lamborn, K.R.3
-
43
-
-
21044431575
-
Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme
-
Chang SM, Wen P, Cloughesy T, et al. Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme. Invest New Drugs. 2005;23:357-361.
-
(2005)
Invest New Drugs
, vol.23
, pp. 357-361
-
-
Chang, S.M.1
Wen, P.2
Cloughesy, T.3
-
44
-
-
23944453425
-
Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: A North Central Cancer Treatment Group Study
-
Galanis E, Buckner JC, Maurer MJ, et al. Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study. J Clin Oncol. 2005;23:5294-5304.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5294-5304
-
-
Galanis, E.1
Buckner, J.C.2
Maurer, M.J.3
-
45
-
-
66149183000
-
A phase I trial of enzastaurin in patients with recurrent gliomas
-
Kreisl TN, Kim L, Moore K, et al. A phase I trial of enzastaurin in patients with recurrent gliomas. Clin Cancer Res. 2009;15: 3617-3623.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3617-3623
-
-
Kreisl, T.N.1
Kim, L.2
Moore, K.3
-
46
-
-
33747058029
-
Phase II trial of tipifarnib in patients with recurrent malignant glioma either receiving or not receiving enzyme-inducing antiepileptic drugs: A North American Brain Tumor Consortium Study
-
Cloughesy TF, Wen PY, Robins HI, et al. Phase II trial of tipifarnib in patients with recurrent malignant glioma either receiving or not receiving enzyme-inducing antiepileptic drugs: a North American Brain Tumor Consortium Study. J Clin Oncol. 2006;24:3651-3656.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3651-3656
-
-
Cloughesy, T.F.1
Wen, P.Y.2
Robins, H.I.3
-
47
-
-
65349141942
-
Phase II trial of vorinostat in recurrent glioblastoma multiforme: A north central cancer treatment group study
-
Galanis E, Jaeckle KA, Maurer MJ, et al. Phase II trial of vorinostat in recurrent glioblastoma multiforme: a north central cancer treatment group study. J Clin Oncol. 2009;27:2052-2058.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2052-2058
-
-
Galanis, E.1
Jaeckle, K.A.2
Maurer, M.J.3
-
48
-
-
77953681462
-
Brain cancer stem cells as targets of novel therapies
-
In: Van Meir EG, ed., New York: Humana Press (Springer)
-
Atkinson JM, Gilbertson RJ, Rich JN. Brain cancer stem cells as targets of novel therapies. In: Van Meir EG, ed. CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st ed. New York: Humana Press (Springer); 2009:1157-1175.
-
(2009)
CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st Ed
, pp. 1157-1175
-
-
Atkinson, J.M.1
Gilbertson, R.J.2
Rich, J.N.3
-
49
-
-
35348822482
-
Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies
-
Stommel JM, Kimmelman AC, Ying H, et al. Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies. Science. 2007;318:287-290.
-
(2007)
Science
, vol.318
, pp. 287-290
-
-
Stommel, J.M.1
Kimmelman, A.C.2
Ying, H.3
-
50
-
-
75049084471
-
Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma
-
Reardon DA, Desjardins A, Vredenburgh JJ, et al. Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma. J Neurooncol. 2010;96:219-230.
-
(2010)
J Neurooncol
, vol.96
, pp. 219-230
-
-
Reardon, D.A.1
Desjardins, A.2
Vredenburgh, J.J.3
-
51
-
-
45249083767
-
Phase I study of erlotinib and CCI-779 (temsirolimus) for patients with recurrent malignant gliomas (NABTC 04-02)
-
Robins HI, Wen PY, Chang SM, et al. Phase I study of erlotinib and CCI-779 (temsirolimus) for patients with recurrent malignant gliomas (NABTC 04-02). J Clin Oncol. 2007;25:2057.
-
(2057)
J Clin Oncol
, vol.2007
, pp. 25
-
-
Robins, H.I.1
Wen, P.Y.2
Chang, S.M.3
-
52
-
-
38849208347
-
Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma
-
Cloughesy TF, Yoshimoto K, Nghiemphu P, et al. Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma. PLoS Med. 2008;5:e8.
-
(2008)
PLoS Med
, vol.e8
, pp. 5
-
-
Cloughesy, T.F.1
Yoshimoto, K.2
Nghiemphu, P.3
-
53
-
-
34447632643
-
Angiogenesis in brain tumours
-
Jain RK, di Tomaso E, Duda DG, Loeffler JS, Sorensen AG, Batchelor TT. Angiogenesis in brain tumours. Nat Rev Neurosci. 2007;8:610-622.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 610-622
-
-
Jain, R.K.1
di Tomaso, E.2
Duda, D.G.3
Loeffler, J.S.4
Sorensen, A.G.5
Batchelor, T.T.6
-
54
-
-
77953676047
-
Bone marrow-derived cells in GBM neovascularization
-
In: Van Meir EG, ed., New York: Humana Press (Springer)
-
Bergers G. Bone marrow-derived cells in GBM neovascularization. In: Van Meir EG, ed. CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st ed. New York: Humana Press (Springer); 2009:749-773.
-
(2009)
CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st Ed
, pp. 749-773
-
-
Bergers, G.1
-
55
-
-
0032941495
-
Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angio genesis
-
Schmidt NO, Westphal M, Hagel C, et al. Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angio genesis. Int J Cancer. 1999;84:10-18.
-
(1999)
Int J Cancer
, vol.84
, pp. 10-18
-
-
Schmidt, N.O.1
Westphal, M.2
Hagel, C.3
-
56
-
-
34547931473
-
Neuropilin-1 promotes human glioma progression through potentiating the activity of the HGF/SF autocrine pathway
-
Hu B, Guo P, Bar-Joseph I, et al. Neuropilin-1 promotes human glioma progression through potentiating the activity of the HGF/SF autocrine pathway. Oncogene. 2007;26:5577-5586.
-
(2007)
Oncogene
, vol.26
, pp. 5577-5586
-
-
Hu, B.1
Guo, P.2
Bar-Joseph, I.3
-
57
-
-
0033580889
-
Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF
-
Holash J, Maisonpierre PC, Compton D, et al. Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science. 1999;284:1994-1998.
-
(1999)
Science
, vol.284
, pp. 1994-1998
-
-
Holash, J.1
Maisonpierre, P.C.2
Compton, D.3
-
58
-
-
7944220649
-
Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2
-
Oliner J, Min H, Leal J, et al. Suppression of angiogenesis and tumor growth by selective inhibition of angiopoietin-2. Cancer Cell. 2004;6:507-516.
-
(2004)
Cancer Cell
, vol.6
, pp. 507-516
-
-
Oliner, J.1
Min, H.2
Leal, J.3
-
59
-
-
33845877157
-
Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis
-
Noguera-Troise I, Daly C, Papadopoulos NJ, et al. Blockade of Dll4 inhibits tumour growth by promoting non-productive angiogenesis. Nature. 2006;444:1032-1037.
-
(2006)
Nature
, vol.444
, pp. 1032-1037
-
-
Noguera-Troise, I.1
Daly, C.2
Papadopoulos, N.J.3
-
60
-
-
32944482137
-
Bevacizumab (Avastin) and CPT-11 (Camptosar) in the treatment of relapsed malignant glioma
-
Stark Vance V. Bevacizumab (Avastin) and CPT-11 (Camptosar) in the treatment of relapsed malignant glioma. Neurooncol. 2005;7:369.
-
(2005)
Neurooncol
, vol.7
, pp. 369
-
-
Stark Vance, V.1
-
61
-
-
60649116273
-
Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: Impact on local control and patient survival
-
Narayana A, Kelly P, Golfinos J, et al. Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: impact on local control and patient survival. J Neurosurg. 2009;110:173-180.
-
(2009)
J Neurosurg
, vol.110
, pp. 173-180
-
-
Narayana, A.1
Kelly, P.2
Golfinos, J.3
-
62
-
-
65249185501
-
Bevacizumab and chemotherapy for recurrent glioblastoma: A single-institution experience
-
Nghiemphu PL, Liu W, Lee Y, et al. Bevacizumab and chemotherapy for recurrent glioblastoma: a single-institution experience. Neurology. 2009;72:1217-1222.
-
(2009)
Neurology
, vol.72
, pp. 1217-1222
-
-
Nghiemphu, P.L.1
Liu, W.2
Lee, Y.3
-
63
-
-
58149090856
-
Bevacizumab plus irinotecan in the treatment patients with progressive recurrent malignant brain tumours
-
Poulsen HS, Grunnet K, Sorensen M, et al. Bevacizumab plus irinotecan in the treatment patients with progressive recurrent malignant brain tumours. Acta Oncol. 2009;48:52-58.
-
(2009)
Acta Oncol
, vol.48
, pp. 52-58
-
-
Poulsen, H.S.1
Grunnet, K.2
Sorensen, M.3
-
64
-
-
58149456505
-
Efficacy, safety and patterns of response and recurrence in patients with recurrent high-grade gliomas treated with bevacizumabplusirinotecan
-
Zuniga RM, Torcuator R, Jain R, et al. Efficacy, safety and patterns of response and recurrence in patients with recurrent high-grade gliomas treated with bevacizumabplusirinotecan. JNeurooncol.2009; 91:329-336.
-
(2009)
JNeurooncol
, vol.91
, pp. 329-336
-
-
Zuniga, R.M.1
Torcuator, R.2
Jain, R.3
-
65
-
-
46149123043
-
Chinot O, et al. [Bevacizumab/irinotecan. An active treatment for recurrent high grade gliomas: Preliminary results of an ANOCEF multicenter study]
-
Guiu S, Taillibert S, Chinot O, et al. [Bevacizumab/irinotecan. An active treatment for recurrent high grade gliomas: preliminary results of an ANOCEF multicenter study]. Rev Neurol (Paris). 2008; 164:588-594.
-
(2008)
Rev Neurol (Paris)
, vol.164
, pp. 588-594
-
-
Guiu, S.1
Taillibert, S.2
-
66
-
-
33646675851
-
MRI in patients with highgrade gliomas treated with bevacizumab and chemotherapy
-
Pope WB, Lai A, Nghiemphu P, Mischel P, Cloughesy TF. MRI in patients with highgrade gliomas treated with bevacizumab and chemotherapy. Neurology. 2006;66: 1258-1260.
-
(2006)
Neurology
, vol.66
, pp. 1258-1260
-
-
Pope, W.B.1
Lai, A.2
Nghiemphu, P.3
Mischel, P.4
Cloughesy, T.F.5
-
67
-
-
0033897173
-
AphaseII study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse
-
Yung W, Albright R, Olson J, etal. AphaseII study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse. Br J Cancer. 2000;83:588-593.
-
(2000)
Br J Cancer
, vol.83
, pp. 588-593
-
-
Yung, W.1
Albright, R.2
Olson, J.3
-
69
-
-
0032855728
-
Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor Group
-
Yung WK, Prados MD, Yaya-Tur R, et al. Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor Group. J Clin Oncol. 1999;17:2762-2771.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2762-2771
-
-
Yung, W.K.1
Prados, M.D.2
Yaya-Tur, R.3
-
70
-
-
70350461699
-
Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
-
Friedman HS, Prados MD, Wen PY, et al. Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J Clin Oncol. 2009;27:4733-4740.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4733-4740
-
-
Friedman, H.S.1
Prados, M.D.2
Wen, P.Y.3
-
72
-
-
59949083263
-
Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma
-
Kreisl TN, Kim L, Moore K, et al. Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma. J Clin Oncol. 2009;27:740-745.
-
(2009)
J Clin Oncol
, vol.27
, pp. 740-745
-
-
Kreisl, T.N.1
Kim, L.2
Moore, K.3
-
73
-
-
33846149645
-
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
-
Batchelor TT, Sorensen AG, di Tomaso E, et al. AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell. 2007; 11:83-95.
-
(2007)
Cancer Cell
, vol.11
, pp. 83-95
-
-
Batchelor, T.T.1
Sorensen, A.G.2
di Tomaso, E.3
-
74
-
-
67650463119
-
A vascular normalization index as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients
-
Sorensen AG, Batchelor TT, Zhang WT, et al. A vascular normalization index as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients. Cancer Res. 2009;69:5296-5300.
-
(2009)
Cancer Res
, vol.69
, pp. 5296-5300
-
-
Sorensen, A.G.1
Batchelor, T.T.2
Zhang, W.T.3
-
75
-
-
0344837389
-
Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment
-
Guo P, Hu B, Gu W, et al. Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment. Am J Pathol. 2003;162:1083-1093.
-
(2003)
Am J Pathol
, vol.162
, pp. 1083-1093
-
-
Guo, P.1
Hu, B.2
Gu, W.3
-
77
-
-
52949140417
-
Mature results of a phase I/IIa trial of the integrininhibitorcilengitide(EMD121974) added to standard concomitant and adjuvant temozolomide and radiotherapy for newly diagnosed glioblastoma
-
Stupp R, Goldbrunner R, Neyns B, et al. Mature results of a phase I/IIa trial of the integrininhibitorcilengitide(EMD121974) added to standard concomitant and adjuvant temozolomide and radiotherapy for newly diagnosed glioblastoma. Neurooncol. 2007;9:517.
-
(2007)
Neurooncol
, vol.9
, pp. 517
-
-
Stupp, R.1
Goldbrunner, R.2
Neyns, B.3
-
79
-
-
1442290142
-
Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms
-
Erber R, Thurnher A, Katsen A, et al. Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms. FASEB J. 2004;18:338-340.
-
(2004)
FASEB J
, vol.18
, pp. 338-340
-
-
Erber, R.1
Thurnher, A.2
Katsen, A.3
-
80
-
-
13444275480
-
Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion
-
Bellail AC, Hunter SB, Brat DJ, Tan C, Van Meir EG. Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion. Int J Biochem Cell Biol. 2004;36:1046-1069.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 1046-1069
-
-
Bellail, A.C.1
Hunter, S.B.2
Brat, D.J.3
Tan, C.4
van Meir, E.G.5
-
81
-
-
79952732293
-
Glioma invasion: Mechanisms and targeting opportunities
-
In: Van Meir EG, ed.
-
Viapiano MS, Lawler SE. Glioma invasion: mechanisms and targeting opportunities. In: Van Meir EG, ed. CNS Cancer: Models, Markers, Prognostic Factors, Targets and TherapeuticApproaches.1sted.NewYork: Humana Press (Springer); 2009:1219-1252.
-
(2009)
CNS Cancer: Models, Markers, Prognostic Factors, Targets and TherapeuticApproaches.1sted.NewYork: Humana Press (Springer)
, pp. 1219-1252
-
-
Viapiano, M.S.1
Lawler, S.E.2
-
82
-
-
77953667395
-
Harnessing T-cell immunity to target brain tumors
-
In: Van Meir EG, ed., New York: Humana Press (Springer)
-
Walker PR, Prins RM, Dietrich P-Y, Liau LM. Harnessing T-cell immunity to target brain tumors. In: Van Meir EG, ed. CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st ed. New York: Humana Press (Springer); 2009:1165-1217.
-
(2009)
CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st Ed
, pp. 1165-1217
-
-
Walker, P.R.1
Prins, R.M.2
Dietrich, P.-Y.3
Liau, L.M.4
-
83
-
-
0030856117
-
Upregulation of interleukin 8 by oxygen-deprived cells in glioblastoma suggests a role in leukocyte activation, chemotaxis, and angiogenesis
-
Desbaillets I, Diserens AC, Tribolet N, Hamou MF, Van Meir EG. Upregulation of interleukin 8 by oxygen-deprived cells in glioblastoma suggests a role in leukocyte activation, chemotaxis, and angiogenesis. J Exp Med. 1997;186:1201-1212.
-
(1997)
J Exp Med
, vol.186
, pp. 1201-1212
-
-
Desbaillets, I.1
Diserens, A.C.2
Tribolet, N.3
Hamou, M.F.4
van Meir, E.G.5
-
84
-
-
77953676877
-
Molecular targets for antibody-mediated immunotherapy of malignant glioma
-
In: Van Meir EG, ed., New York: Humana Press (Springer)
-
Ayriss JE, Kuan C-T, Boulton ST, Reardon DA, Bigner DD. Molecular targets for antibody-mediated immunotherapy of malignant glioma. In: Van Meir EG, ed. CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st ed. New York: Humana Press (Springer); 2009:865-898.
-
(2009)
CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st Ed
, pp. 865-898
-
-
Ayriss, J.E.1
Kuan, C.-T.2
Boulton, S.T.3
Reardon, D.A.4
Bigner, D.D.5
-
85
-
-
0037161024
-
Chemotherapy in adult highgrade glioma: A systematic review and meta-analysis of individual patient data from 12 randomised trials
-
Stewart LA. Chemotherapy in adult highgrade glioma: a systematic review and meta-analysis of individual patient data from 12 randomised trials. Lancet. 2002; 359:1011-1018.
-
(2002)
Lancet
, vol.359
, pp. 1011-1018
-
-
Stewart, L.A.1
-
86
-
-
75849146316
-
MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma
-
Rivera AL, Pelloski CE, Gilbert MR, Colman H, De La Cruz C, Sulman EP, Bekele BN, Aldape KD. MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma. Neuro Oncol. 2010;12:116-121.
-
(2010)
Neuro Oncol
, vol.12
, pp. 116-121
-
-
Rivera, A.L.1
Pelloski, C.E.2
Gilbert, M.R.3
Colman, H.4
de la Cruz, C.5
Sulman, E.P.6
Bekele, B.N.7
Aldape, K.D.8
-
87
-
-
0037692954
-
Marked inactivation of O6-alkylguanine- DNA alkyltransferase activity with protracted temozolomide schedules
-
Tolcher AW, Gerson SL, Denis L, et al. Marked inactivation of O6-alkylguanine- DNA alkyltransferase activity with protracted temozolomide schedules. Br J Cancer. 2003;88:1004-1011.
-
(2003)
Br J Cancer
, vol.88
, pp. 1004-1011
-
-
Tolcher, A.W.1
Gerson, S.L.2
Denis, L.3
-
88
-
-
36749020617
-
Phase I trial of single-dose temozolomide and continuous administration of O6-benzylguanine in children with brain tumors: A pediatric brain tumor consortium report
-
Broniscer A, Gururangan S, MacDonald TJ, et al. Phase I trial of single-dose temozolomide and continuous administration of O6-benzylguanine in children with brain tumors: a pediatric brain tumor consortium report. Clin Cancer Res. 2007; 13:6712-6718.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6712-6718
-
-
Broniscer, A.1
Gururangan, S.2
Macdonald, T.J.3
-
89
-
-
34249006299
-
ABT-888, an orally active poly(ADPribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models
-
Donawho CK, Luo Y, Penning TD, et al. ABT-888, an orally active poly(ADPribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models. Clin Cancer Res. 2007;13: 2728-2737.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2728-2737
-
-
Donawho, C.K.1
Luo, Y.2
Penning, T.D.3
-
90
-
-
77953668780
-
Proteomic discovery of biomarkers in the cerebrospinal fluid of brain tumor patients
-
In: Van Meir EG, ed., New York: Humana Press (Springer)
-
Khwaja FW, Van Meir EG. Proteomic discovery of biomarkers in the cerebrospinal fluid of brain tumor patients. In: Van Meir EG, ed. CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st ed. New York: Humana Press (Springer); 2009:577-614.
-
(2009)
CNS Cancer: Models, Markers, Prognostic Factors, Targets and Therapeutic Approaches. 1st Ed
, pp. 577-614
-
-
Khwaja, F.W.1
van Meir, E.G.2
-
91
-
-
33847343860
-
Proteomic identification of biomarkers in the cerebrospinal fluid (CSF) of astrocytoma patients
-
Khwaja FW, Reed MS, Olson JJ, et al. Proteomic identification of biomarkers in the cerebrospinal fluid (CSF) of astrocytoma patients. J Proteome Res. 2007;6:559-570.
-
(2007)
J Proteome Res
, vol.6
, pp. 559-570
-
-
Khwaja, F.W.1
Reed, M.S.2
Olson, J.J.3
-
92
-
-
0025027767
-
Human glioblastoma cells release interleukin 6 in vivo and in vitro
-
Van Meir EG, Sawamura Y, Diserens A-C, Hamou M-F, de Tribolet N. Human glioblastoma cells release interleukin 6 in vivo and in vitro. Cancer Res. 1990;50:6683-6688.
-
(1990)
Cancer Res
, vol.50
, pp. 6683-6688
-
-
van Meir, E.G.1
Sawamura, Y.2
Diserens, A.-C.3
Hamou, M.-F.4
de Tribolet, N.5
-
93
-
-
0026806805
-
Interleukin-8 is produced in neoplastic and infectious diseases of the human central nervous system
-
Van Meir E, Ceska M, Effenberger F, et al. Interleukin-8 is produced in neoplastic and infectious diseases of the human central nervous system. Cancer Res. 1992; 52:4297-4305.
-
(1992)
Cancer Res
, vol.52
, pp. 4297-4305
-
-
van Meir, E.1
Ceska, M.2
Effenberger, F.3
-
94
-
-
0027443077
-
Quantitative study of monocyte chemoattractant protein-1 (MCP-1) in cerebrospinal fluid and cyst fluid from patients with malignant glioma
-
Kuratsu J, Yoshizato K, Yoshimura T, Leonard EJ, Takeshima H, Ushio Y. Quantitative study of monocyte chemoattractant protein-1 (MCP-1) in cerebrospinal fluid and cyst fluid from patients with malignant glioma. J Natl Cancer Inst. 1993;85:1836-1839.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1836-1839
-
-
Kuratsu, J.1
Yoshizato, K.2
Yoshimura, T.3
Leonard, E.J.4
Takeshima, H.5
Ushio, Y.6
-
95
-
-
0026506708
-
Granulocyte-macrophage colony-stimulating factor (GM-CSF) production by glioblastoma cells: Despite the presence of inducing signals GM-CSF is not expressed in vivo
-
Frei K, Piani D, Malipiero UV, Van Meir EG, de Tribolet N, Fontana A. Granulocyte-macrophage colony-stimulating factor (GM-CSF) production by glioblastoma cells: despite the presence of inducing signals GM-CSF is not expressed in vivo. J Immunol. 1992;148:3140-3146.
-
(1992)
J Immunol
, vol.148
, pp. 3140-3146
-
-
Frei, K.1
Piani, D.2
Malipiero, U.V.3
van Meir, E.G.4
de Tribolet, N.5
Fontana, A.6
-
96
-
-
0027959172
-
Human astrocytomas and glioblastomas express monocyte chemoattractant protein-1 (MCP-1) in vivo and in vitro
-
Desbaillets I, Tada M, de Tribolet N, Diserens AC, Hamou MF, Van Meir EG. Human astrocytomas and glioblastomas express monocyte chemoattractant protein-1 (MCP-1) in vivo and in vitro. Int J Cancer. 1994;58:240-247.
-
(1994)
Int J Cancer
, vol.58
, pp. 240-247
-
-
Desbaillets, I.1
Tada, M.2
de Tribolet, N.3
Diserens, A.C.4
Hamou, M.F.5
van Meir, E.G.6
-
97
-
-
33751293920
-
Attractin is elevated in the cerebrospinal fluid (CSF) of patients with malignant astrocytoma and mediates glioma cell migration
-
Khwaja F, Duke-Cohan JS, Brat DJ, Van Meir EG. Attractin is elevated in the cerebrospinal fluid (CSF) of patients with malignant astrocytoma and mediates glioma cell migration. Clin Cancer Res. 2006;12:6331-6336.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6331-6336
-
-
Khwaja, F.1
Duke-Cohan, J.S.2
Brat, D.J.3
van Meir, E.G.4
-
98
-
-
41849136479
-
Application of neuroendoscopy to intraventricular lesions
-
Cappabianca P, Cinalli G, Gangemi M, et al. Application of neuroendoscopy to intraventricular lesions. Neurosurgery. 2008; 62(suppl 2):575-597.
-
(2008)
Neurosurgery
, vol.62
, Issue.SUPPL. 2
, pp. 575-597
-
-
Cappabianca, P.1
Cinalli, G.2
Gangemi, M.3
-
99
-
-
33747257716
-
Endoscopic resection of solid intraventricular brain tumors
-
Souweidane MM, Luther N. Endoscopic resection of solid intraventricular brain tumors. J Neurosurg. 2006;105:271-278.
-
(2006)
J Neurosurg
, vol.105
, pp. 271-278
-
-
Souweidane, M.M.1
Luther, N.2
-
101
-
-
0033038020
-
PerneczkyA.Endoscopicthirdventriculostomy: Outcome analysis of 100 consecutive procedures
-
Hopf NJ, Grunert P, Fries G, Resch KD, PerneczkyA.Endoscopicthirdventriculostomy: outcome analysis of 100 consecutive procedures. Neurosurgery. 1999;44: 795-804.
-
(1999)
Neurosurgery
, vol.44
, pp. 795-804
-
-
Hopf, N.J.1
Grunert, P.2
Fries, G.3
Resch, K.D.4
-
102
-
-
33644626927
-
Endoscopic resection of hypothalamic hamartoma using a novel variable aspiration tissue resector
-
ONS166-ONS169
-
Lekovic GP, Gonzalez LF, Feiz-Erfan I, Rekate HL. Endoscopic resection of hypothalamic hamartoma using a novel variable aspiration tissue resector. Neurosurgery. 2006; 58:ONS166-ONS169.
-
(2006)
Neurosurgery
, pp. 58
-
-
Lekovic, G.P.1
Gonzalez, L.F.2
Feiz-Erfan, I.3
Rekate, H.L.4
-
103
-
-
48949107730
-
Glioma extent of resection and its impact on patient outcome
-
Sanai N, Berger MS. Glioma extent of resection and its impact on patient outcome. Neurosurgery. 2008;62:753-764.
-
(2008)
Neurosurgery
, vol.62
, pp. 753-764
-
-
Sanai, N.1
Berger, M.S.2
-
105
-
-
65349096845
-
Fluorescenceguided resection of malignant gliomas using 5-aminolevulinic acid: Practical use, risks,andpitfalls
-
Tonn JC, Stummer W. Fluorescenceguided resection of malignant gliomas using 5-aminolevulinic acid: practical use, risks,andpitfalls. ClinNeurosurg.2008;55: 20-26.
-
(2008)
ClinNeurosurg
, vol.55
, pp. 20-26
-
-
Tonn, J.C.1
Stummer, W.2
-
106
-
-
33645986455
-
Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: A randomised controlled multicentre phase III trial
-
Stummer W, Pichlmeier U, Meinel T, Wiestler OD, Zanella F, Reulen HJ. Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol. 2006;7: 392-401.
-
(2006)
Lancet Oncol
, vol.7
, pp. 392-401
-
-
Stummer, W.1
Pichlmeier, U.2
Meinel, T.3
Wiestler, O.D.4
Zanella, F.5
Reulen, H.J.6
-
107
-
-
55849097685
-
Metallic iron nanoparticles for MRI contrast enhancement and local hyperthermia
-
Hadjipanayis CG, Bonder MJ, Balakrishnan S, Wang X, Mao H, Hadjipanayis GC. Metallic iron nanoparticles for MRI contrast enhancement and local hyperthermia. Small. 2008;4:1925-1929.
-
(2008)
Small
, vol.4
, pp. 1925-1929
-
-
Hadjipanayis, C.G.1
Bonder, M.J.2
Balakrishnan, S.3
Wang, X.4
Mao, H.5
Hadjipanayis, G.C.6
-
108
-
-
0018568970
-
An analysis of dose-effect relationship in the radiotherapy of malignant gliomas
-
Walker MD, Strike TA, Sheline GE. An analysis of dose-effect relationship in the radiotherapy of malignant gliomas. Int J Radiat Oncol Biol Phys. 1979;5:1725-1731.
-
(1979)
Int J Radiat Oncol Biol Phys
, vol.5
, pp. 1725-1731
-
-
Walker, M.D.1
Strike, T.A.2
Sheline, G.E.3
-
109
-
-
0348109480
-
Comparison of intensity-modulated radiotherapy with three-dimensional conformal radiation therapy planning for glioblastoma multiforme
-
Chan MF, Schupak K, Burman C, Chui CS, Ling CC. Comparison of intensity-modulated radiotherapy with three-dimensional conformal radiation therapy planning for glioblastoma multiforme. Med Dosim. 2003;28:261-265.
-
(2003)
Med Dosim
, vol.28
, pp. 261-265
-
-
Chan, M.F.1
Schupak, K.2
Burman, C.3
Chui, C.S.4
Ling, C.C.5
-
112
-
-
26944460870
-
The American Society for Therapeutic Radiology and Oncology (ASTRO) evidencebased review of the role of radiosurgery for malignant glioma
-
Tsao MN, Mehta MP, Whelan TJ, et al. The American Society for Therapeutic Radiology and Oncology (ASTRO) evidencebased review of the role of radiosurgery for malignant glioma. Int J Radiat Oncol Biol Phys. 2005;63:47-55.
-
(2005)
Int J Radiat Oncol Biol Phys
, vol.63
, pp. 47-55
-
-
Tsao, M.N.1
Mehta, M.P.2
Whelan, T.J.3
-
113
-
-
4744345914
-
Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme: Report of Radiation Therapy Oncology Group 93-05 protocol
-
Souhami L, Seiferheld W, Brachman D, et al. Randomized comparison of stereotactic radiosurgery followed by conventional radiotherapy with carmustine to conventional radiotherapy with carmustine for patients with glioblastoma multiforme: report of Radiation Therapy Oncology Group 93-05 protocol. Int J Radiat Oncol Biol Phys. 2004;60:853-860.
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.60
, pp. 853-860
-
-
Souhami, L.1
Seiferheld, W.2
Brachman, D.3
-
114
-
-
2242458568
-
Phase II study of high central dose Gamma Knife radiosurgery and marimastat in patients with recurrent malignant glioma
-
Larson DA, Prados M, Lamborn KR, et al. Phase II study of high central dose Gamma Knife radiosurgery and marimastat in patients with recurrent malignant glioma. Int J Radiat Oncol Biol Phys. 2002;54:1397-1404.
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.54
, pp. 1397-1404
-
-
Larson, D.A.1
Prados, M.2
Lamborn, K.R.3
-
115
-
-
27644459039
-
Stereotactic radiosurgery (SRS): Treatment option for recurrent glioblastoma multiforme (GBM)
-
Combs SE, Widmer V, Thilmann C, Hof H, Debus J, Schulz-Ertner D. Stereotactic radiosurgery (SRS): treatment option for recurrent glioblastoma multiforme (GBM). Cancer. 2005;104:2168-2173.
-
(2005)
Cancer
, vol.104
, pp. 2168-2173
-
-
Combs, S.E.1
Widmer, V.2
Thilmann, C.3
Hof, H.4
Debus, J.5
Schulz-Ertner, D.6
-
116
-
-
0031392473
-
The Cyberknife: A frameless robotic system for radiosurgery
-
Adler JR Jr, Chang SD, Murphy MJ, Doty J, Geis P, Hancock SL. The Cyberknife: a frameless robotic system for radiosurgery. Stereotact Funct Neurosurg. 1997; 69:124-128.
-
(1997)
Stereotact Funct Neurosurg
, vol.69
, pp. 124-128
-
-
Adler Jr., J.R.1
Chang, S.D.2
Murphy, M.J.3
Doty, J.4
Geis, P.5
Hancock, S.L.6
-
118
-
-
58149202436
-
Novalis frameless image-guided noninvasive radiosurgery: Initial experience
-
Wurm RE, Erbel S, Schwenkert I, et al. Novalis frameless image-guided noninvasive radiosurgery: initial experience. Neurosurgery. 2008;62(suppl 5):A11-A17.
-
(2008)
Neurosurgery
, vol.62
, Issue.SUPPL. 5
-
-
Wurm, R.E.1
Erbel, S.2
Schwenkert, I.3
-
119
-
-
0032719514
-
Accelerated fractionated proton/photon irradiation to 90 cobalt gray equivalent for glioblastoma multiforme: Results of a phase II prospective trial
-
Fitzek MM, Thornton AF, Rabinov JD, et al. Accelerated fractionated proton/photon irradiation to 90 cobalt gray equivalent for glioblastoma multiforme: results of a phase II prospective trial. J Neurosurg. 1999;91:251-260.
-
(1999)
J Neurosurg
, vol.91
, pp. 251-260
-
-
Fitzek, M.M.1
Thornton, A.F.2
Rabinov, J.D.3
-
120
-
-
0037087538
-
Survival and failure patterns of high-grade gliomas after three-dimensional conformal radiotherapy
-
Chan JL, Lee SW, Fraass BA, et al. Survival and failure patterns of high-grade gliomas after three-dimensional conformal radiotherapy. J Clin Oncol. 2002;20:1635-1642.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1635-1642
-
-
Chan, J.L.1
Lee, S.W.2
Fraass, B.A.3
-
121
-
-
0022997570
-
A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery: Final report of an RTOG study
-
Nelson DF, Diener-West M, Weinstein AS, et al. A randomized comparison of misonidazole sensitized radiotherapy plus BCNU and radiotherapy plus BCNU for treatment of malignant glioma after surgery: final report of an RTOG study. Int J Radiat Oncol Biol Phys. 1986;12:1793-1800.
-
(1986)
Int J Radiat Oncol Biol Phys
, vol.12
, pp. 1793-1800
-
-
Nelson, D.F.1
Diener-West, M.2
Weinstein, A.S.3
-
122
-
-
12144286887
-
Phase III randomized study of radiotherapy plus procarbazine, lomustine, and vincristine with or without BUdR for treatment of anaplastic astrocytoma: Final report of RTOG 9404
-
Prados MD, Seiferheld W, Sandler HM, et al. Phase III randomized study of radiotherapy plus procarbazine, lomustine, and vincristine with or without BUdR for treatment of anaplastic astrocytoma: final report of RTOG 9404. Int J Radiat Oncol Biol Phys. 2004;58:1147-1152.
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.58
, pp. 1147-1152
-
-
Prados, M.D.1
Seiferheld, W.2
Sandler, H.M.3
-
123
-
-
35448929133
-
Differential radiosensitizing potential of temozolomide in MGMT promoter methylated glioblastoma multiforme cell lines
-
van Nifterik KA, van den Berg J, Stalpers LJ, et al. Differential radiosensitizing potential of temozolomide in MGMT promoter methylated glioblastoma multiforme cell lines. Int J Radiat Oncol Biol Phys. 2007;69:1246-1253.
-
(2007)
Int J Radiat Oncol Biol Phys
, vol.69
, pp. 1246-1253
-
-
van Nifterik, K.A.1
van den Berg, J.2
Stalpers, L.J.3
-
124
-
-
0032168534
-
Conversion of a radioresistant phenotype to a more sensitive one by disabling erbB receptor signaling in human cancer cells
-
O'Rourke DM, Kao GD, Singh N, et al. Conversion of a radioresistant phenotype to a more sensitive one by disabling erbB receptor signaling in human cancer cells. Proc Natl Acad Sc i U S A. 1998;95:10842-10847.
-
(1998)
Proc Natl Acad Sc I U S A
, vol.95
, pp. 10842-10847
-
-
O'Rourke, D.M.1
Kao, G.D.2
Singh, N.3
-
125
-
-
3042581834
-
Mutantepidermalgrowth factor receptor displays increased signaling through the phosphatidylinositol-3 kinase/AKT pathway and promotes radioresistance in cells of astrocytic origin
-
Li B, Yuan M, Kim IA, Chang CM, Bernhard EJ, Shu HK. Mutantepidermalgrowth factor receptor displays increased signaling through the phosphatidylinositol-3 kinase/AKT pathway and promotes radioresistance in cells of astrocytic origin. Oncogene. 2004;23:4594-4602.
-
(2004)
Oncogene
, vol.23
, pp. 4594-4602
-
-
Li, B.1
Yuan, M.2
Kim, I.A.3
Chang, C.M.4
Bernhard, E.J.5
Shu, H.K.6
-
126
-
-
56749142790
-
Advances in neuroimaging techniques for the evaluation of tumor growth, vascular permeability, and angiogenesis in gliomas
-
Gerstner ER, Sorensen AG, Jain RK, Batchelor TT. Advances in neuroimaging techniques for the evaluation of tumor growth, vascular permeability, and angiogenesis in gliomas. Curr Opin Neurol. 2008;21:728-735.
-
(2008)
Curr Opin Neurol
, vol.21
, pp. 728-735
-
-
Gerstner, E.R.1
Sorensen, A.G.2
Jain, R.K.3
Batchelor, T.T.4
-
127
-
-
0027389952
-
Cerebral glioma: Evaluation with methionine PET
-
Ogawa T, Shishido F, Kanno I, et al. Cerebral glioma: evaluation with methionine PET. Radiology. 1993;186:45-53.
-
(1993)
Radiology
, vol.186
, pp. 45-53
-
-
Ogawa, T.1
Shishido, F.2
Kanno, I.3
-
128
-
-
0032588608
-
Synthesis and evaluation of [18F]1-amino- 3-fluorocyclobutane-1-carboxylic acid to image brain tumors
-
Shoup TM, Olson J, Hoffman JM, et al. Synthesis and evaluation of [18F]1-amino- 3-fluorocyclobutane-1-carboxylic acid to image brain tumors. J Nucl Med. 1999;40: 331-338.
-
(1999)
J Nucl Med
, vol.40
, pp. 331-338
-
-
Shoup, T.M.1
Olson, J.2
Hoffman, J.M.3
-
129
-
-
23044460494
-
Imaging proliferation in brain tumors with 18F-FLT PET: Comparison with 18F- FDG
-
Chen W, Cloughesy T, Kamdar N, et al. Imaging proliferation in brain tumors with 18F-FLT PET: comparison with 18F- FDG. J Nucl Med. 2005;46:945-952.
-
(2005)
J Nucl Med
, vol.46
, pp. 945-952
-
-
Chen, W.1
Cloughesy, T.2
Kamdar, N.3
-
130
-
-
33645969631
-
Correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in gliomas using 18F-fluoromisonidazole, 18F-FDG PET, and immunohistochemical studies
-
Cher LM, Murone C, Lawrentschuk N, et al. Correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in gliomas using 18F-fluoromisonidazole, 18F-FDG PET, and immunohistochemical studies. J Nucl Med. 2006;47:410-418.
-
(2006)
J Nucl Med
, vol.47
, pp. 410-418
-
-
Cher, L.M.1
Murone, C.2
Lawrentschuk, N.3
-
131
-
-
63649116770
-
Laser accelerated radiotherapy: Is it on its way to the clinic?
-
Martin M. Laser accelerated radiotherapy: is it on its way to the clinic? J Natl Cancer Inst. 2009;101:450-451.
-
(2009)
J Natl Cancer Inst
, vol.101
, pp. 450-451
-
-
Martin, M.1
-
132
-
-
77953669725
-
Real-time polymerase chain reaction technique determines absolute copy number of plasma methylated MGMT gene promoter copies in newly diagnosed malignant glioma patients
-
Abstract 22073
-
Weaver KD, Pierce L, Herman JG, Grossman SA. Real-time polymerase chain reaction technique determines absolute copy number of plasma methylated MGMT gene promoter copies in newly diagnosed malignant glioma patients. J Clin Oncol. 2008;26: Abstract 22073.
-
(2008)
J Clin Oncol
, vol.26
-
-
Weaver, K.D.1
Pierce, L.2
Herman, J.G.3
Grossman, S.A.4
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