Global DNA methylation level in whole blood as a biomarker in head and neck squamous cell carcinoma

Cancer Epidemiology Biomarkers and Prevention

Volumn 16, Issue 1, 2007, Pages 108-114

  Hsiung, Debra Ting ^a   Marsit, Carmen J ^a   Houseman, E Andres ^a   Eddy, Karen ^a   Furniss, C Sloane ^a   McClean, Michael D ^b   Kelsey, Karl T ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; BISULFITE; DNA; FOLIC ACID; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2);

ADULT; ANTIBODY RESPONSE; ARTICLE; BLOOD ANALYSIS; CANCER RISK; CIGARETTE SMOKING; CONTROLLED STUDY; DNA METHYLATION; FEMALE; GENE SEQUENCE; GENETIC ASSOCIATION; GENOTYPE; HEAD AND NECK CARCINOMA; HUMAN; HUMAN PAPILLOMAVIRUS TYPE 16; MAJOR CLINICAL STUDY; MALE; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; RACE DIFFERENCE; SQUAMOUS CELL CARCINOMA; UNITED STATES;

ALCOHOL DRINKING; BIOLOGICAL MARKERS; BOSTON; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; DNA METHYLATION; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MIDDLE AGED; SMOKING;

EID: 33846619807     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-06-0636     Document Type: Article

References (54)

1. Döbróssy L. Epidemiology of head and neck cancer: magnitude of the problem. Cancer Metastasis Rev 2005;24:9-17.
2. Jemal A, Murray T, Ward E, et al. Cancer statistics, 2005. CA Cancer J Clin 2005;55:10-30.
3. Thomas GR, Nadiminti H, Regalado J. Molecular predictors of clinical outcome in patients with head and neck squamous cell carcinoma. Int J Exp Pathol 2005;86:347-63.
4. Chin D, Boyle GM, Williams RM, et al. Novel markers for poor prognosis in head and neck cancer. Int J Cancer 2005;113:789-97.
5. Blot WJ, McLaughlin JK, Winn DM, et al. Smoking and drinking in relation to oral and pharyngeal cancer. Cancer Res 1988;48:3282-7.
6. Elwood JM, Pearson JC, Skippen DH, Jackson SM. Alcohol, smoking, social and occupational factors in the aetiology of cancer of the oral cavity, pharynx, and larynx. Int J Cancer 1984;34:603-12.
7. Olsen J, Sabreo S, Fasting U. Interaction of alcohol and tobacco as risk factors in cancer of the laryngeal region. J Epidemiol Community Health 1985;39: 165-8.
8. Olsen J, Sabroe S, Ipsen J. Effect of combined alcohol and tobacco exposure on risk of cancer of the hypopharynx. J Epidemiol Community Health 1985; 39:304-7.
9. Zeka A, Gore R, Kriebel D. Effects of alcohol and tobacco on aerodigestive cancer risks: a meta-regression analysis. Cancer Causes Control 2003;14: 897-906.
10. Rothman K, Keller A. The effect of joint exposure to alcohol and tobacco on risk of cancer of the mouth and pharynx. J Chronic Dis 1972;25:711-6.
11. McKaig RG, Baric RS, Olshan AF. Human papillomavirus and head and neck cancer: epidemiology and molecular biology. Head Neck 1998;20: 250-65.
12. Herrero R, Castellsague X, Pawlita M, et al. Human papillomavirus and oral cancer: The International Agency for Research on Cancer Multicenter Study. J Natl Cancer Inst 2003;95:1772-83.
13. Franceschi S, Munoz N, Bosch X, Snijders P, Walboomers J. Human papillomavirus and cancers of the upper aerodigestive tract: a review of epidemiological and experimental evidence. Cancer Epidemiol Biomarkers Prev 1996;5:567-75.
14. Chen R, Aaltonen L-M, Vaheri A. Human papillomavirus type 16 in head and neck carcinogenesis. Rev Med Virol 2005;15:351-63.
15. Gillison ML, Shah KV. Human papillomavirus-associated head and neck squamous cell carcinoma: mounting evidence for an etiologic role for human papillomavirus in a subset of head and neck cancers. Curr Opin Oncol 2001; 13:183-8.
16. Ringstrom E, Peters E, Hasegawa M, Posner M, Liu M, Kelsey KT. Human papillomavirus type 16 and squamous cell carcinoma of the head and neck. Clin Cancer Res 2002;8:3187-92.
17. Valentine JA, Scott J, West CR, St Hill CA. A histological analysis of the early effects of alcohol and tobacco usage on human lingual epithelium. J Oral Pathol 1985;14:654-65.
18. Molina P, Hoek J, Nelson S, et al. Mechanisms of alcohol-induced tissue injury. Alcohol Clin Exp Res 2003;27:563-75.
19. Issa JP. Aging, DNA methylation, and cancer. Crit Rev Oncol Hematol 1999; 32:31-43.
20. Feinberg AP, Tycko B. The history of cancer epigenetics. Nat Rev Cancer 2004;4:143-53.
21. Ha PK, Califano JA. Promoter methylation and inactivation of tumour-suppressor genes in oral squamous-cell carcinoma. Lancet Oncol 2006;7: 77-82.
22. Baylin SB, Herman JG. DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet 2000;16:168-74.
23. Eng C, Herman JG, Baylin SB. A bird's eye view of global methylation. Nat Genet 2000;24:101-2.
24. Pogribny IP, James SJ. De novo methylation of the p!6INK4A gene in early preneoplastic liver and tumors induced by folate/methyl deficiency in rats. Cancer Lett 2002;187:69-75.
25. Ehrlich M. DNA methylation in cancer: too much, but also too little. Oncogene 2002;21:5400-13.
26. Feinberg AP, Gehrke CW, Kuo KC, Ehrlich M. Reduced genomic 5-methylcytosine content in human colonic neoplasia. Cancer Res 1988;48: 1159-61.
27. Feinberg AP, Vogelstein B. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 1983;301:89-92.
28. Hoffmann M, Schulz W. Causes and consequences of DNA hypomethylation in human cancer. Biochem Cell Biol 2005;83:296-321.
29. Roman-Gomez J, Jimenez-Velasco A, Agirre X, et al. Promoter hypomethylation of the LINE-1 retrorransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia. Oncogene 2005;24:7213-23.
30. Eden A, Gaudet F, Waghmare A, Jaenisch R. Chromosomal instability and tumors promoted by DNA hypomethylation. Science 2003;300:455.
31. Gaudet F, Hodgson JG, Eden A, et al. Induction of tumors in mice by genomic hypomethylation. Science 2003;300:489-92.
32. Ehrlich M. DNA hypomethylation, cancer, the immunodeficiency, centromeric region instability, facial anomalies syndrome, and chromosomal rearrangements. J Nutr 2002;132:2424-98.
33. Muiznieks I, Doerfler W. The impact of 5′-CG-3′ methylation on the activity of different eukaryotic promoters: a comparative study. FEBS Lett 1994;344: 251-4.
34. Kaneda A, Tsukamoto T, Takamura-Enya T, et al. Frequent hypomethylation in multiple promoter CpG islands is associated with global hypomethylation, but not with frequent promoter hypermethylation. Cancer Sci 2004;95:58-64.
35. Balaghi M, Wagner C. DNA methylation in folate deficiency: use of CpG methylase. Biochem Biophys Res Commun 1993;193:1184-90.
36. Piyathilake C, Johanning G, Macalusom M, et al. Localized folate and vitamin B-12 deficiency in squamous cell lung cancer is associated with global DNA hypomethylation. Nutr Cancer 2000;37:99-107.
37. Ostertag EM, Kazazian HH, Jr. Biology of mammalian L1 retrotransposons. Ann Rev Genet 2001;35:501-38.
38. Chalitchagorn K, Shuangshoti S, Hourpai N, et al. Distinctive pattern of LINE-1 methylation level in normal tissues and the association with carcinogenesis. Oncogene 2004;23:8841-6.
39. Peters ES, McClean MD, Liu M, Eisen EA, Mueller N, Kelsey KT. The ADH1C polymorphism modifies the risk of squamous cell carcinoma of the head and neck associated with alcohol and tobacco use. Cancer Epidemiol Biomarkers Prev 2005;14:476-82.
40. Willett WC, Sampson L, Stampfer MJ, et al. Reproducibility and validity of a semiquantitative food frequency questionnaire. Am J Epidemiol 1985;122: 51-65.
41. Willett WC, Sampson L, Browne ML, et al. The use of a self-administered questionnaire to assess diet four years in the past. Am J Epidemiol 1988;127: 188-99.
42. Lin DY, Wei LJ, Ying Z. Model-checking techniques based on cumulative residuals. Biometrics 2002;58:1-12.
43. James SJ, Pogribny IP, Pogribna M, Miller BJ, Jernigan S, Melnyk S. Mechanisms of DNA damage, DNA hypomethylation, and tumor progression in the folate/methyl-deficient rat model of hepatocarcinogenesis. J Nutr 2003;133:3740-7S.
44. Badal S, Badal V, Calleja-Macias IE, et al. The human papillomavirus-18 genome is efficiently targeted by cellular DNA methylation. Virology 2004; 324:483-92.
45. Kim K, Garner-Hamrick PA, Fisher C, Lee D, Lambert PF. Methylation patterns of papillomavirus DNA, its influence on E2 function, and implications in viral infection. J Virol 2003;77:12450-9.
46. Badal V, Chuang LS, Tan EH, et al. CpG methylation of human papillomavirus type 16 DNA in cervical cancer cell lines and in clinical specimens: genomic hypomethylation correlates with carcinogenic progression. J Virol 2003;77:6227-34.
47. Liu L, Zhang J, Bates S, et al. A methylation profile of in vitro immortalized human cell lines. Int J Oncol 2005;26:275-85.
48. Duensing S, Lee LY, Duensing A, et al. The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle. Proc Natl Acad Sci U S A 2000;97:10002-7.
49. Neumann A, Lyons H, Shen H, et al. Methylenetetrahydrofolate reductase polymorphisms and risk of squamous cell carcinoma of the head and neck: a case-control analysis. Int J Cancer 2005;115:131-6.
50. Paludetti G, Almadori G, Bussu F, Galli J, Cadoni G, Maurizi M. Hypofolatemia as a risk factor for head and neck cancer. Otorhinolaryngol 2005;62:12-24.
51. Almadori G, Bussu F, Galli J, et al. Serum levels of folate, homocysteine, and vitamin B12 in head and neck squamous cell carcinoma and in laryngeal leukoplakia. Cancer 2005;103:284-92.
52. Song J, Medline A, Mason JB, Gallinger S, Kim Y-I. Effects of dietary folate on intestinal tumorigenesis in the ApcMin mouse. Cancer Res 2000;60:5434-40.
53. Baggott J, Vaughn W, Juliana M, Eto I, Krumdieck C, Grubbs C. Effects of folate deficiency and supplementation on methylnitrosourea-induced rat mammary tumors. J Natl Cancer Inst 1992;84:1740-4.
54. Feinberg AP, Ohlsson R, Henikoff S. The epigenetic progenitor origin of human cancer. Nat Rev Genet 2006;7:21-33.