-
1
-
-
77956056197
-
Prognostic significance of histological grading, p53 status, YKL-40 expression, and IDH1 mutations in pediatric high-grade gliomas
-
Antonelli M., Buttarelli F.R., Arcella A., Nobusawa S., Donofrio V., Oghaki H., Giangaspero F. Prognostic significance of histological grading, p53 status, YKL-40 expression, and IDH1 mutations in pediatric high-grade gliomas. J. Neurooncol. 2010, 99:209-215.
-
(2010)
J. Neurooncol.
, vol.99
, pp. 209-215
-
-
Antonelli, M.1
Buttarelli, F.R.2
Arcella, A.3
Nobusawa, S.4
Donofrio, V.5
Oghaki, H.6
Giangaspero, F.7
-
2
-
-
56749156414
-
Analysis of the IDH1 codon 132 mutation in brain tumors
-
Balss J., Meyer J., Mueller W., Korshunov A., Hartmann C., von Deimling A. Analysis of the IDH1 codon 132 mutation in brain tumors. Acta Neuropathol. 2008, 116:597-602.
-
(2008)
Acta Neuropathol.
, vol.116
, pp. 597-602
-
-
Balss, J.1
Meyer, J.2
Mueller, W.3
Korshunov, A.4
Hartmann, C.5
von Deimling, A.6
-
3
-
-
77954240113
-
A distinct spectrum of copy number aberrations in pediatric high-grade gliomas
-
Bax D.A., Mackay A., Little S.E., Carvalho D., Viana-Pereira M., Tamber N., Grigoriadis A.E., Ashworth A., Reis R.M., Ellison D.W., et al. A distinct spectrum of copy number aberrations in pediatric high-grade gliomas. Clin. Cancer Res. 2010, 16:3368-3377.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 3368-3377
-
-
Bax, D.A.1
Mackay, A.2
Little, S.E.3
Carvalho, D.4
Viana-Pereira, M.5
Tamber, N.6
Grigoriadis, A.E.7
Ashworth, A.8
Reis, R.M.9
Ellison, D.W.10
-
4
-
-
84861883921
-
Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk
-
Brinkman A.B., Gu H., Bartels S.J., Zhang Y., Matarese F., Simmer F., Marks H., Bock C., Gnirke A., Meissner A., Stunnenberg H.G. Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk. Genome Res. 2012, 22:1128-1138.
-
(2012)
Genome Res.
, vol.22
, pp. 1128-1138
-
-
Brinkman, A.B.1
Gu, H.2
Bartels, S.J.3
Zhang, Y.4
Matarese, F.5
Simmer, F.6
Marks, H.7
Bock, C.8
Gnirke, A.9
Meissner, A.10
Stunnenberg, H.G.11
-
5
-
-
33947574174
-
Clinical and molecular characteristics of malignant transformation of low-grade glioma in children
-
Broniscer A., Baker S.J., West A.N., Fraser M.M., Proko E., Kocak M., Dalton J., Zambetti G.P., Ellison D.W., Kun L.E., et al. Clinical and molecular characteristics of malignant transformation of low-grade glioma in children. J. Clin. Oncol. 2007, 25:682-689.
-
(2007)
J. Clin. Oncol.
, vol.25
, pp. 682-689
-
-
Broniscer, A.1
Baker, S.J.2
West, A.N.3
Fraser, M.M.4
Proko, E.5
Kocak, M.6
Dalton, J.7
Zambetti, G.P.8
Ellison, D.W.9
Kun, L.E.10
-
6
-
-
71549122009
-
Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors
-
Capper D., Weissert S., Balss J., Habel A., Meyer J., Jäger D., Ackermann U., Tessmer C., Korshunov A., Zentgraf H., et al. Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors. Brain Pathol. 2010, 20:245-254.
-
(2010)
Brain Pathol.
, vol.20
, pp. 245-254
-
-
Capper, D.1
Weissert, S.2
Balss, J.3
Habel, A.4
Meyer, J.5
Jäger, D.6
Ackermann, U.7
Tessmer, C.8
Korshunov, A.9
Zentgraf, H.10
-
7
-
-
79955547561
-
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases
-
Chowdhury R., Yeoh K.K., Tian Y.M., Hillringhaus L., Bagg E.A., Rose N.R., Leung I.K., Li X.S., Woon E.C., Yang M., et al. The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. EMBO Rep. 2011, 12:463-469.
-
(2011)
EMBO Rep.
, vol.12
, pp. 463-469
-
-
Chowdhury, R.1
Yeoh, K.K.2
Tian, Y.M.3
Hillringhaus, L.4
Bagg, E.A.5
Rose, N.R.6
Leung, I.K.7
Li, X.S.8
Woon, E.C.9
Yang, M.10
-
8
-
-
79251470741
-
DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma
-
Christensen B.C., Smith A.A., Zheng S., Koestler D.C., Houseman E.A., Marsit C.J., Wiemels J.L., Nelson H.H., Karagas M.R., Wrensch M.R., et al. DNA methylation, isocitrate dehydrogenase mutation, and survival in glioma. J. Natl. Cancer Inst. 2011, 103:143-153.
-
(2011)
J. Natl. Cancer Inst.
, vol.103
, pp. 143-153
-
-
Christensen, B.C.1
Smith, A.A.2
Zheng, S.3
Koestler, D.C.4
Houseman, E.A.5
Marsit, C.J.6
Wiemels, J.L.7
Nelson, H.H.8
Karagas, M.R.9
Wrensch, M.R.10
-
9
-
-
72049125350
-
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
-
Dang L., White D.W., Gross S., Bennett B.D., Bittinger M.A., Driggers E.M., Fantin V.R., Jang H.G., Jin S., Keenan M.C., et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 2009, 462:739-744.
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
Bennett, B.D.4
Bittinger, M.A.5
Driggers, E.M.6
Fantin, V.R.7
Jang, H.G.8
Jin, S.9
Keenan, M.C.10
-
11
-
-
77953955724
-
The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3
-
Drané P., Ouararhni K., Depaux A., Shuaib M., Hamiche A. The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3. Genes Dev. 2010, 24:1253-1265.
-
(2010)
Genes Dev.
, vol.24
, pp. 1253-1265
-
-
Drané, P.1
Ouararhni, K.2
Depaux, A.3
Shuaib, M.4
Hamiche, A.5
-
12
-
-
0034069652
-
Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation
-
Gibbons R.J., McDowell T.L., Raman S., O'Rourke D.M., Garrick D., Ayyub H., Higgs D.R. Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation. Nat. Genet. 2000, 24:368-371.
-
(2000)
Nat. Genet.
, vol.24
, pp. 368-371
-
-
Gibbons, R.J.1
McDowell, T.L.2
Raman, S.3
O'Rourke, D.M.4
Garrick, D.5
Ayyub, H.6
Higgs, D.R.7
-
13
-
-
77649099092
-
Distinct factors control histone variant H3.3 localization at specific genomic regions
-
Goldberg A.D., Banaszynski L.A., Noh K.M., Lewis P.W., Elsaesser S.J., Stadler S., Dewell S., Law M., Guo X., Li X., et al. Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell 2010, 140:678-691.
-
(2010)
Cell
, vol.140
, pp. 678-691
-
-
Goldberg, A.D.1
Banaszynski, L.A.2
Noh, K.M.3
Lewis, P.W.4
Elsaesser, S.J.5
Stadler, S.6
Dewell, S.7
Law, M.8
Guo, X.9
Li, X.10
-
14
-
-
33645702660
-
DNA methyltransferases control telomere length and telomere recombination in mammalian cells
-
Gonzalo S., Jaco I., Fraga M.F., Chen T., Li E., Esteller M., Blasco M.A. DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nat. Cell Biol. 2006, 8:416-424.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 416-424
-
-
Gonzalo, S.1
Jaco, I.2
Fraga, M.F.3
Chen, T.4
Li, E.5
Esteller, M.6
Blasco, M.A.7
-
15
-
-
79960700556
-
Altered telomeres in tumors with ATRX and DAXX mutations
-
Heaphy C.M., de Wilde R.F., Jiao Y., Klein A.P., Edil B.H., Shi C., Bettegowda C., Rodriguez F.J., Eberhart C.G., Hebbar S., et al. Altered telomeres in tumors with ATRX and DAXX mutations. Science 2011, 333:425.
-
(2011)
Science
, vol.333
, pp. 425
-
-
Heaphy, C.M.1
de Wilde, R.F.2
Jiao, Y.3
Klein, A.P.4
Edil, B.H.5
Shi, C.6
Bettegowda, C.7
Rodriguez, F.J.8
Eberhart, C.G.9
Hebbar, S.10
-
16
-
-
79959667403
-
An evolutionarily 'young' lysine residue in histone H3 attenuates transcriptional output in Saccharomyces cerevisiae
-
Hyland E.M., Molina H., Poorey K., Jie C., Xie Z., Dai J., Qian J., Bekiranov S., Auble D.T., Pandey A., Boeke J.D. An evolutionarily 'young' lysine residue in histone H3 attenuates transcriptional output in Saccharomyces cerevisiae. Genes Dev. 2011, 25:1306-1319.
-
(2011)
Genes Dev.
, vol.25
, pp. 1306-1319
-
-
Hyland, E.M.1
Molina, H.2
Poorey, K.3
Jie, C.4
Xie, Z.5
Dai, J.6
Qian, J.7
Bekiranov, S.8
Auble, D.T.9
Pandey, A.10
Boeke, J.D.11
-
17
-
-
0037112529
-
Identification of silencing of nine genes in human gastric cancers
-
Kaneda A., Kaminishi M., Yanagihara K., Sugimura T., Ushijima T. Identification of silencing of nine genes in human gastric cancers. Cancer Res. 2002, 62:6645-6650.
-
(2002)
Cancer Res.
, vol.62
, pp. 6645-6650
-
-
Kaneda, A.1
Kaminishi, M.2
Yanagihara, K.3
Sugimura, T.4
Ushijima, T.5
-
18
-
-
80054993342
-
Spatio-temporal transcriptome of the human brain
-
Kang H.J., Kawasawa Y.I., Cheng F., Zhu Y., Xu X., Li M., Sousa A.M., Pletikos M., Meyer K.A., Sedmak G., et al. Spatio-temporal transcriptome of the human brain. Nature 2011, 478:483-489.
-
(2011)
Nature
, vol.478
, pp. 483-489
-
-
Kang, H.J.1
Kawasawa, Y.I.2
Cheng, F.3
Zhu, Y.4
Xu, X.5
Li, M.6
Sousa, A.M.7
Pletikos, M.8
Meyer, K.A.9
Sedmak, G.10
-
19
-
-
84865863019
-
K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
-
Khuong-Quang D.A., Buczkowicz P., Rakopoulos P., Liu X.Y., Fontebasso A.M., Bouffet E., Bartels U., Albrecht S., Schwartzentruber J., Letourneau L., et al. K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas. Acta Neuropathol. 2012, 124:439-447.
-
(2012)
Acta Neuropathol.
, vol.124
, pp. 439-447
-
-
Khuong-Quang, D.A.1
Buczkowicz, P.2
Rakopoulos, P.3
Liu, X.Y.4
Fontebasso, A.M.5
Bouffet, E.6
Bartels, U.7
Albrecht, S.8
Schwartzentruber, J.9
Letourneau, L.10
-
20
-
-
2442669017
-
The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas
-
Ligon K.L., Alberta J.A., Kho A.T., Weiss J., Kwaan M.R., Nutt C.L., Louis D.N., Stiles C.D., Rowitch D.H. The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas. J. Neuropathol. Exp. Neurol. 2004, 63:499-509.
-
(2004)
J. Neuropathol. Exp. Neurol.
, vol.63
, pp. 499-509
-
-
Ligon, K.L.1
Alberta, J.A.2
Kho, A.T.3
Weiss, J.4
Kwaan, M.R.5
Nutt, C.L.6
Louis, D.N.7
Stiles, C.D.8
Rowitch, D.H.9
-
21
-
-
34347207046
-
-
IARC, Lyon
-
Louis D.N., Ohgaki H., Wiestler O.D., Cavenee W.K. WHO Classification of Tumors of the Central Nervous System 2007, IARC, Lyon.
-
(2007)
WHO Classification of Tumors of the Central Nervous System
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
Cavenee, W.K.4
-
22
-
-
84858796262
-
IDH mutation impairs histone demethylation and results in a block to cell differentiation
-
Lu C., Ward P.S., Kapoor G.S., Rohle D., Turcan S., Abdel-Wahab O., Edwards C.R., Khanin R., Figueroa M.E., Melnick A., et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature 2012, 483:474-478.
-
(2012)
Nature
, vol.483
, pp. 474-478
-
-
Lu, C.1
Ward, P.S.2
Kapoor, G.S.3
Rohle, D.4
Turcan, S.5
Abdel-Wahab, O.6
Edwards, C.R.7
Khanin, R.8
Figueroa, M.E.9
Melnick, A.10
-
23
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer Genome Atlas Research Network
-
McLendon R., Friedman A., Bigner D., Van Meir E.G., Brat D.J., Mastrogianakis M., Olson J.J., Mikkelsen T., Lehman N., Aldape K., et al. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008, 455:1061-1068. Cancer Genome Atlas Research Network.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
McLendon, R.1
Friedman, A.2
Bigner, D.3
Van Meir, E.G.4
Brat, D.J.5
Mastrogianakis, M.6
Olson, J.J.7
Mikkelsen, T.8
Lehman, N.9
Aldape, K.10
-
24
-
-
79952217981
-
The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma
-
Mehta S., Huillard E., Kesari S., Maire C.L., Golebiowski D., Harrington E.P., Alberta J.A., Kane M.F., Theisen M., Ligon K.L., et al. The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma. Cancer Cell 2011, 19:359-371.
-
(2011)
Cancer Cell
, vol.19
, pp. 359-371
-
-
Mehta, S.1
Huillard, E.2
Kesari, S.3
Maire, C.L.4
Golebiowski, D.5
Harrington, E.P.6
Alberta, J.A.7
Kane, M.F.8
Theisen, M.9
Ligon, K.L.10
-
25
-
-
49649125042
-
Genome-scale DNA methylation maps of pluripotent and differentiated cells
-
Meissner A., Mikkelsen T.S., Gu H., Wernig M., Hanna J., Sivachenko A., Zhang X., Bernstein B.E., Nusbaum C., Jaffe D.B., et al. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 2008, 454:766-770.
-
(2008)
Nature
, vol.454
, pp. 766-770
-
-
Meissner, A.1
Mikkelsen, T.S.2
Gu, H.3
Wernig, M.4
Hanna, J.5
Sivachenko, A.6
Zhang, X.7
Bernstein, B.E.8
Nusbaum, C.9
Jaffe, D.B.10
-
26
-
-
0038724494
-
Consensus clustering: A resampling-based method for class discovery and visualization of gene expression microarray data
-
Monti S., Tamayo P., Mesirov J., Golub T. Consensus clustering: A resampling-based method for class discovery and visualization of gene expression microarray data. Mach. Learn. 2003, 52:91-118.
-
(2003)
Mach. Learn.
, vol.52
, pp. 91-118
-
-
Monti, S.1
Tamayo, P.2
Mesirov, J.3
Golub, T.4
-
27
-
-
77952108366
-
Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
-
Cancer Genome Atlas Research Network
-
Noushmehr H., Weisenberger D.J., Diefes K., Phillips H.S., Pujara K., Berman B.P., Pan F., Pelloski C.E., Sulman E.P., Bhat K.P., et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 2010, 17:510-522. Cancer Genome Atlas Research Network.
-
(2010)
Cancer Cell
, vol.17
, pp. 510-522
-
-
Noushmehr, H.1
Weisenberger, D.J.2
Diefes, K.3
Phillips, H.S.4
Pujara, K.5
Berman, B.P.6
Pan, F.7
Pelloski, C.E.8
Sulman, E.P.9
Bhat, K.P.10
-
28
-
-
78449275473
-
KIAA0495/PDAM is frequently downregulated in oligodendroglial tumors and its knockdown by siRNA induces cisplatin resistance in glioma cells
-
Pang J.C., Li K.K., Lau K.M., Ng Y.L., Wong J., Chung N.Y., Li H.M., Chui Y.L., Lui V.W., Chen Z.P., et al. KIAA0495/PDAM is frequently downregulated in oligodendroglial tumors and its knockdown by siRNA induces cisplatin resistance in glioma cells. Brain Pathol. 2010, 20:1021-1032.
-
(2010)
Brain Pathol.
, vol.20
, pp. 1021-1032
-
-
Pang, J.C.1
Li, K.K.2
Lau, K.M.3
Ng, Y.L.4
Wong, J.5
Chung, N.Y.6
Li, H.M.7
Chui, Y.L.8
Lui, V.W.9
Chen, Z.P.10
-
29
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma multiforme
-
Parsons D.W., Jones S., Zhang X., Lin J.C., Leary R.J., Angenendt P., Mankoo P., Carter H., Siu I.M., Gallia G.L., et al. An integrated genomic analysis of human glioblastoma multiforme. Science 2008, 321:1807-1812.
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
Mankoo, P.7
Carter, H.8
Siu, I.M.9
Gallia, G.L.10
-
30
-
-
77954596239
-
Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease
-
Paugh B.S., Qu C., Jones C., Liu Z., Adamowicz-Brice M., Zhang J., Bax D.A., Coyle B., Barrow J., Hargrave D., et al. Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease. J. Clin. Oncol. 2010, 28:3061-3068.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 3061-3068
-
-
Paugh, B.S.1
Qu, C.2
Jones, C.3
Liu, Z.4
Adamowicz-Brice, M.5
Zhang, J.6
Bax, D.A.7
Coyle, B.8
Barrow, J.9
Hargrave, D.10
-
31
-
-
80054771090
-
Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma
-
Paugh B.S., Broniscer A., Qu C., Miller C.P., Zhang J., Tatevossian R.G., Olson J.M., Geyer J.R., Chi S.N., da Silva N.S., et al. Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma. J. Clin. Oncol. 2011, 29:3999-4006.
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 3999-4006
-
-
Paugh, B.S.1
Broniscer, A.2
Qu, C.3
Miller, C.P.4
Zhang, J.5
Tatevossian, R.G.6
Olson, J.M.7
Geyer, J.R.8
Chi, S.N.9
da Silva, N.S.10
-
32
-
-
79951934386
-
TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma
-
Pfaff E., Remke M., Sturm D., Benner A., Witt H., Milde T., von Bueren A.O., Wittmann A., Schöttler A., Jorch N., et al. TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma. J. Clin. Oncol. 2010, 28:5188-5196.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 5188-5196
-
-
Pfaff, E.1
Remke, M.2
Sturm, D.3
Benner, A.4
Witt, H.5
Milde, T.6
von Bueren, A.O.7
Wittmann, A.8
Schöttler, A.9
Jorch, N.10
-
33
-
-
63749118521
-
Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci
-
Pfister S., Remke M., Benner A., Mendrzyk F., Toedt G., Felsberg J., Wittmann A., Devens F., Gerber N.U., Joos S., et al. Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci. J. Clin. Oncol. 2009, 27:1627-1636.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 1627-1636
-
-
Pfister, S.1
Remke, M.2
Benner, A.3
Mendrzyk, F.4
Toedt, G.5
Felsberg, J.6
Wittmann, A.7
Devens, F.8
Gerber, N.U.9
Joos, S.10
-
34
-
-
78951489314
-
IDH1 mutations are common in malignant gliomas arising in adolescents: A report from the Children's Oncology Group
-
Published online August 20, 2010
-
Pollack I.F., Hamilton R.L., Sobol R.W., Nikiforova M.N., Lyons-Weiler M.A., Laframboise W.A., Burger P.C., Brat D.J., Rosenblum M.K., Holmes E.J., et al. IDH1 mutations are common in malignant gliomas arising in adolescents: A report from the Children's Oncology Group. Childs Nerv. Syst. 2011, 27:87-94. Published online August 20, 2010. 10.1007/s00381-010-1264-1.
-
(2011)
Childs Nerv. Syst.
, vol.27
, pp. 87-94
-
-
Pollack, I.F.1
Hamilton, R.L.2
Sobol, R.W.3
Nikiforova, M.N.4
Lyons-Weiler, M.A.5
Laframboise, W.A.6
Burger, P.C.7
Brat, D.J.8
Rosenblum, M.K.9
Holmes, E.J.10
-
35
-
-
84857527038
-
Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas
-
Puget S., Philippe C., Bax D.A., Job B., Varlet P., Junier M.P., Andreiuolo F., Carvalho D., Reis R., Guerrini-Rousseau L., et al. Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas. PLoS ONE 2012, 7:e30313.
-
(2012)
PLoS ONE
, vol.7
-
-
Puget, S.1
Philippe, C.2
Bax, D.A.3
Job, B.4
Varlet, P.5
Junier, M.P.6
Andreiuolo, F.7
Carvalho, D.8
Reis, R.9
Guerrini-Rousseau, L.10
-
36
-
-
75849131906
-
Genome-wide profiling using single-nucleotide polymorphism arrays identifies novel chromosomal imbalances in pediatric glioblastomas
-
Qu H.Q., Jacob K., Fatet S., Ge B., Barnett D., Delattre O., Faury D., Montpetit A., Solomon L., Hauser P., et al. Genome-wide profiling using single-nucleotide polymorphism arrays identifies novel chromosomal imbalances in pediatric glioblastomas. Neuro-oncol. 2010, 12:153-163.
-
(2010)
Neuro-oncol.
, vol.12
, pp. 153-163
-
-
Qu, H.Q.1
Jacob, K.2
Fatet, S.3
Ge, B.4
Barnett, D.5
Delattre, O.6
Faury, D.7
Montpetit, A.8
Solomon, L.9
Hauser, P.10
-
37
-
-
76549137130
-
Oncogenic BRAF mutation with CDKN2A inactivation is characteristic of a subset of pediatric malignant astrocytomas
-
Schiffman J.D., Hodgson J.G., VandenBerg S.R., Flaherty P., Polley M.Y., Yu M., Fisher P.G., Rowitch D.H., Ford J.M., Berger M.S., et al. Oncogenic BRAF mutation with CDKN2A inactivation is characteristic of a subset of pediatric malignant astrocytomas. Cancer Res. 2010, 70:512-519.
-
(2010)
Cancer Res.
, vol.70
, pp. 512-519
-
-
Schiffman, J.D.1
Hodgson, J.G.2
VandenBerg, S.R.3
Flaherty, P.4
Polley, M.Y.5
Yu, M.6
Fisher, P.G.7
Rowitch, D.H.8
Ford, J.M.9
Berger, M.S.10
-
38
-
-
84862777348
-
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
-
Schwartzentruber J., Korshunov A., Liu X.Y., Jones D.T.W., Pfaff E., Jacob K., Sturm D., Fontebasso A.M., Quang D.A., Tönjes M., et al. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 2012, 482:226-231.
-
(2012)
Nature
, vol.482
, pp. 226-231
-
-
Schwartzentruber, J.1
Korshunov, A.2
Liu, X.Y.3
Jones, D.T.W.4
Pfaff, E.5
Jacob, K.6
Sturm, D.7
Fontebasso, A.M.8
Quang, D.A.9
Tönjes, M.10
-
39
-
-
78049359978
-
A pyrosequencing-based assay for the rapid detection of IDH1 mutations in clinical samples
-
Setty P., Hammes J., Rothämel T., Vladimirova V., Kramm C.M., Pietsch T., Waha A. A pyrosequencing-based assay for the rapid detection of IDH1 mutations in clinical samples. J. Mol. Diagn. 2010, 12:750-756.
-
(2010)
J. Mol. Diagn.
, vol.12
, pp. 750-756
-
-
Setty, P.1
Hammes, J.2
Rothämel, T.3
Vladimirova, V.4
Kramm, C.M.5
Pietsch, T.6
Waha, A.7
-
40
-
-
84861916932
-
Bisulfite sequencing of chromatin immunoprecipitated DNA (BisChIP-seq) directly informs methylation status of histone-modified DNA
-
Statham A.L., Robinson M.D., Song J.Z., Coolen M.W., Stirzaker C., Clark S.J. Bisulfite sequencing of chromatin immunoprecipitated DNA (BisChIP-seq) directly informs methylation status of histone-modified DNA. Genome Res. 2012, 22:1120-1127.
-
(2012)
Genome Res.
, vol.22
, pp. 1120-1127
-
-
Statham, A.L.1
Robinson, M.D.2
Song, J.Z.3
Coolen, M.W.4
Stirzaker, C.5
Clark, S.J.6
-
41
-
-
84858796263
-
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
-
Turcan S., Rohle D., Goenka A., Walsh L.A., Fang F., Yilmaz E., Campos C., Fabius A.W., Lu C., Ward P.S., et al. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature 2012, 483:479-483.
-
(2012)
Nature
, vol.483
, pp. 479-483
-
-
Turcan, S.1
Rohle, D.2
Goenka, A.3
Walsh, L.A.4
Fang, F.5
Yilmaz, E.6
Campos, C.7
Fabius, A.W.8
Lu, C.9
Ward, P.S.10
-
42
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Cancer Genome Atlas Research Network
-
Verhaak R.G., Hoadley K.A., Purdom E., Wang V., Qi Y., Wilkerson M.D., Miller C.R., Ding L., Golub T., Mesirov J.P., et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 2010, 17:98-110. Cancer Genome Atlas Research Network.
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
Wang, V.4
Qi, Y.5
Wilkerson, M.D.6
Miller, C.R.7
Ding, L.8
Golub, T.9
Mesirov, J.P.10
-
43
-
-
65649142176
-
Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model
-
Wang Y., Yang J., Zheng H., Tomasek G.J., Zhang P., McKeever P.E., Lee E.Y., Zhu Y. Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model. Cancer Cell 2009, 15:514-526.
-
(2009)
Cancer Cell
, vol.15
, pp. 514-526
-
-
Wang, Y.1
Yang, J.2
Zheng, H.3
Tomasek, G.J.4
Zhang, P.5
McKeever, P.E.6
Lee, E.Y.7
Zhu, Y.8
-
44
-
-
77954182362
-
ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking
-
Wilkerson M.D., Hayes D.N. ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking. Bioinformatics 2010, 26:1572-1573.
-
(2010)
Bioinformatics
, vol.26
, pp. 1572-1573
-
-
Wilkerson, M.D.1
Hayes, D.N.2
-
45
-
-
84862777410
-
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
-
St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project
-
Wu G., Broniscer A., McEachron T.A., Lu C., Paugh B.S., Becksfort J., Qu C., Ding L., Huether R., Parker M., et al. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nat. Genet. 2012, 44:251-253. St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project.
-
(2012)
Nat. Genet.
, vol.44
, pp. 251-253
-
-
Wu, G.1
Broniscer, A.2
McEachron, T.A.3
Lu, C.4
Paugh, B.S.5
Becksfort, J.6
Qu, C.7
Ding, L.8
Huether, R.9
Parker, M.10
-
46
-
-
78651463452
-
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases
-
Xu W., Yang H., Liu Y., Yang Y., Wang P., Kim S.H., Ito S., Yang C., Wang P., Xiao M.T., et al. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell 2011, 19:17-30.
-
(2011)
Cancer Cell
, vol.19
, pp. 17-30
-
-
Xu, W.1
Yang, H.2
Liu, Y.3
Yang, Y.4
Wang, P.5
Kim, S.H.6
Ito, S.7
Yang, C.8
Wang, P.9
Xiao, M.T.10
-
47
-
-
60849115270
-
IDH1 and IDH2 mutations in gliomas
-
Yan H., Parsons D.W., Jin G., McLendon R., Rasheed B.A., Yuan W., Kos I., Batinic-Haberle I., Jones S., Riggins G.J., et al. IDH1 and IDH2 mutations in gliomas. N. Engl. J. Med. 2009, 360:765-773.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 765-773
-
-
Yan, H.1
Parsons, D.W.2
Jin, G.3
McLendon, R.4
Rasheed, B.A.5
Yuan, W.6
Kos, I.7
Batinic-Haberle, I.8
Jones, S.9
Riggins, G.J.10
-
48
-
-
77950487385
-
Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets
-
Zarghooni M., Bartels U., Lee E., Buczkowicz P., Morrison A., Huang A., Bouffet E., Hawkins C. Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets. J. Clin. Oncol. 2010, 28:1337-1344.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 1337-1344
-
-
Zarghooni, M.1
Bartels, U.2
Lee, E.3
Buczkowicz, P.4
Morrison, A.5
Huang, A.6
Bouffet, E.7
Hawkins, C.8
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