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Volumn 22, Issue 4, 2012, Pages 425-437

Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

(78)  Sturm, Dominik a   Witt, Hendrik a,b   Hovestadt, Volker a   Khuong Quang, Dong Anh c   Jones, David T W a   Konermann, Carolin a   Pfaff, Elke a   Tönjes, Martje a   Sill, Martin a   Bender, Sebastian a   Kool, Marcel a   Zapatka, Marc a   Becker, Natalia a   Zucknick, Manuela a   Hielscher, Thomas a   Liu, Xiao Yang c   Fontebasso, Adam M d   Ryzhova, Marina e   Albrecht, Steffen d   Jacob, Karine c   more..


Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; HISTONE H3; ISOCITRATE DEHYDROGENASE 1; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2;

EID: 84867606428     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccr.2012.08.024     Document Type: Article
Times cited : (1449)

References (48)
  • 1
    • 77956056197 scopus 로고    scopus 로고
    • Prognostic significance of histological grading, p53 status, YKL-40 expression, and IDH1 mutations in pediatric high-grade gliomas
    • Antonelli M., Buttarelli F.R., Arcella A., Nobusawa S., Donofrio V., Oghaki H., Giangaspero F. Prognostic significance of histological grading, p53 status, YKL-40 expression, and IDH1 mutations in pediatric high-grade gliomas. J. Neurooncol. 2010, 99:209-215.
    • (2010) J. Neurooncol. , vol.99 , pp. 209-215
    • Antonelli, M.1    Buttarelli, F.R.2    Arcella, A.3    Nobusawa, S.4    Donofrio, V.5    Oghaki, H.6    Giangaspero, F.7
  • 11
    • 77953955724 scopus 로고    scopus 로고
    • The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3
    • Drané P., Ouararhni K., Depaux A., Shuaib M., Hamiche A. The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3. Genes Dev. 2010, 24:1253-1265.
    • (2010) Genes Dev. , vol.24 , pp. 1253-1265
    • Drané, P.1    Ouararhni, K.2    Depaux, A.3    Shuaib, M.4    Hamiche, A.5
  • 12
    • 0034069652 scopus 로고    scopus 로고
    • Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation
    • Gibbons R.J., McDowell T.L., Raman S., O'Rourke D.M., Garrick D., Ayyub H., Higgs D.R. Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation. Nat. Genet. 2000, 24:368-371.
    • (2000) Nat. Genet. , vol.24 , pp. 368-371
    • Gibbons, R.J.1    McDowell, T.L.2    Raman, S.3    O'Rourke, D.M.4    Garrick, D.5    Ayyub, H.6    Higgs, D.R.7
  • 14
    • 33645702660 scopus 로고    scopus 로고
    • DNA methyltransferases control telomere length and telomere recombination in mammalian cells
    • Gonzalo S., Jaco I., Fraga M.F., Chen T., Li E., Esteller M., Blasco M.A. DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nat. Cell Biol. 2006, 8:416-424.
    • (2006) Nat. Cell Biol. , vol.8 , pp. 416-424
    • Gonzalo, S.1    Jaco, I.2    Fraga, M.F.3    Chen, T.4    Li, E.5    Esteller, M.6    Blasco, M.A.7
  • 24
    • 79952217981 scopus 로고    scopus 로고
    • The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma
    • Mehta S., Huillard E., Kesari S., Maire C.L., Golebiowski D., Harrington E.P., Alberta J.A., Kane M.F., Theisen M., Ligon K.L., et al. The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma. Cancer Cell 2011, 19:359-371.
    • (2011) Cancer Cell , vol.19 , pp. 359-371
    • Mehta, S.1    Huillard, E.2    Kesari, S.3    Maire, C.L.4    Golebiowski, D.5    Harrington, E.P.6    Alberta, J.A.7    Kane, M.F.8    Theisen, M.9    Ligon, K.L.10
  • 26
    • 0038724494 scopus 로고    scopus 로고
    • Consensus clustering: A resampling-based method for class discovery and visualization of gene expression microarray data
    • Monti S., Tamayo P., Mesirov J., Golub T. Consensus clustering: A resampling-based method for class discovery and visualization of gene expression microarray data. Mach. Learn. 2003, 52:91-118.
    • (2003) Mach. Learn. , vol.52 , pp. 91-118
    • Monti, S.1    Tamayo, P.2    Mesirov, J.3    Golub, T.4
  • 28
    • 78449275473 scopus 로고    scopus 로고
    • KIAA0495/PDAM is frequently downregulated in oligodendroglial tumors and its knockdown by siRNA induces cisplatin resistance in glioma cells
    • Pang J.C., Li K.K., Lau K.M., Ng Y.L., Wong J., Chung N.Y., Li H.M., Chui Y.L., Lui V.W., Chen Z.P., et al. KIAA0495/PDAM is frequently downregulated in oligodendroglial tumors and its knockdown by siRNA induces cisplatin resistance in glioma cells. Brain Pathol. 2010, 20:1021-1032.
    • (2010) Brain Pathol. , vol.20 , pp. 1021-1032
    • Pang, J.C.1    Li, K.K.2    Lau, K.M.3    Ng, Y.L.4    Wong, J.5    Chung, N.Y.6    Li, H.M.7    Chui, Y.L.8    Lui, V.W.9    Chen, Z.P.10
  • 31
    • 80054771090 scopus 로고    scopus 로고
    • Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma
    • Paugh B.S., Broniscer A., Qu C., Miller C.P., Zhang J., Tatevossian R.G., Olson J.M., Geyer J.R., Chi S.N., da Silva N.S., et al. Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma. J. Clin. Oncol. 2011, 29:3999-4006.
    • (2011) J. Clin. Oncol. , vol.29 , pp. 3999-4006
    • Paugh, B.S.1    Broniscer, A.2    Qu, C.3    Miller, C.P.4    Zhang, J.5    Tatevossian, R.G.6    Olson, J.M.7    Geyer, J.R.8    Chi, S.N.9    da Silva, N.S.10
  • 32
    • 79951934386 scopus 로고    scopus 로고
    • TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma
    • Pfaff E., Remke M., Sturm D., Benner A., Witt H., Milde T., von Bueren A.O., Wittmann A., Schöttler A., Jorch N., et al. TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma. J. Clin. Oncol. 2010, 28:5188-5196.
    • (2010) J. Clin. Oncol. , vol.28 , pp. 5188-5196
    • Pfaff, E.1    Remke, M.2    Sturm, D.3    Benner, A.4    Witt, H.5    Milde, T.6    von Bueren, A.O.7    Wittmann, A.8    Schöttler, A.9    Jorch, N.10
  • 33
    • 63749118521 scopus 로고    scopus 로고
    • Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci
    • Pfister S., Remke M., Benner A., Mendrzyk F., Toedt G., Felsberg J., Wittmann A., Devens F., Gerber N.U., Joos S., et al. Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci. J. Clin. Oncol. 2009, 27:1627-1636.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 1627-1636
    • Pfister, S.1    Remke, M.2    Benner, A.3    Mendrzyk, F.4    Toedt, G.5    Felsberg, J.6    Wittmann, A.7    Devens, F.8    Gerber, N.U.9    Joos, S.10
  • 36
    • 75849131906 scopus 로고    scopus 로고
    • Genome-wide profiling using single-nucleotide polymorphism arrays identifies novel chromosomal imbalances in pediatric glioblastomas
    • Qu H.Q., Jacob K., Fatet S., Ge B., Barnett D., Delattre O., Faury D., Montpetit A., Solomon L., Hauser P., et al. Genome-wide profiling using single-nucleotide polymorphism arrays identifies novel chromosomal imbalances in pediatric glioblastomas. Neuro-oncol. 2010, 12:153-163.
    • (2010) Neuro-oncol. , vol.12 , pp. 153-163
    • Qu, H.Q.1    Jacob, K.2    Fatet, S.3    Ge, B.4    Barnett, D.5    Delattre, O.6    Faury, D.7    Montpetit, A.8    Solomon, L.9    Hauser, P.10
  • 40
    • 84861916932 scopus 로고    scopus 로고
    • Bisulfite sequencing of chromatin immunoprecipitated DNA (BisChIP-seq) directly informs methylation status of histone-modified DNA
    • Statham A.L., Robinson M.D., Song J.Z., Coolen M.W., Stirzaker C., Clark S.J. Bisulfite sequencing of chromatin immunoprecipitated DNA (BisChIP-seq) directly informs methylation status of histone-modified DNA. Genome Res. 2012, 22:1120-1127.
    • (2012) Genome Res. , vol.22 , pp. 1120-1127
    • Statham, A.L.1    Robinson, M.D.2    Song, J.Z.3    Coolen, M.W.4    Stirzaker, C.5    Clark, S.J.6
  • 42
    • 73649123907 scopus 로고    scopus 로고
    • Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
    • Cancer Genome Atlas Research Network
    • Verhaak R.G., Hoadley K.A., Purdom E., Wang V., Qi Y., Wilkerson M.D., Miller C.R., Ding L., Golub T., Mesirov J.P., et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 2010, 17:98-110. Cancer Genome Atlas Research Network.
    • (2010) Cancer Cell , vol.17 , pp. 98-110
    • Verhaak, R.G.1    Hoadley, K.A.2    Purdom, E.3    Wang, V.4    Qi, Y.5    Wilkerson, M.D.6    Miller, C.R.7    Ding, L.8    Golub, T.9    Mesirov, J.P.10
  • 43
    • 65649142176 scopus 로고    scopus 로고
    • Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model
    • Wang Y., Yang J., Zheng H., Tomasek G.J., Zhang P., McKeever P.E., Lee E.Y., Zhu Y. Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model. Cancer Cell 2009, 15:514-526.
    • (2009) Cancer Cell , vol.15 , pp. 514-526
    • Wang, Y.1    Yang, J.2    Zheng, H.3    Tomasek, G.J.4    Zhang, P.5    McKeever, P.E.6    Lee, E.Y.7    Zhu, Y.8
  • 44
    • 77954182362 scopus 로고    scopus 로고
    • ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking
    • Wilkerson M.D., Hayes D.N. ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking. Bioinformatics 2010, 26:1572-1573.
    • (2010) Bioinformatics , vol.26 , pp. 1572-1573
    • Wilkerson, M.D.1    Hayes, D.N.2
  • 45
    • 84862777410 scopus 로고    scopus 로고
    • Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
    • St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project
    • Wu G., Broniscer A., McEachron T.A., Lu C., Paugh B.S., Becksfort J., Qu C., Ding L., Huether R., Parker M., et al. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nat. Genet. 2012, 44:251-253. St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project.
    • (2012) Nat. Genet. , vol.44 , pp. 251-253
    • Wu, G.1    Broniscer, A.2    McEachron, T.A.3    Lu, C.4    Paugh, B.S.5    Becksfort, J.6    Qu, C.7    Ding, L.8    Huether, R.9    Parker, M.10
  • 46
    • 78651463452 scopus 로고    scopus 로고
    • Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases
    • Xu W., Yang H., Liu Y., Yang Y., Wang P., Kim S.H., Ito S., Yang C., Wang P., Xiao M.T., et al. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell 2011, 19:17-30.
    • (2011) Cancer Cell , vol.19 , pp. 17-30
    • Xu, W.1    Yang, H.2    Liu, Y.3    Yang, Y.4    Wang, P.5    Kim, S.H.6    Ito, S.7    Yang, C.8    Wang, P.9    Xiao, M.T.10
  • 48
    • 77950487385 scopus 로고    scopus 로고
    • Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets
    • Zarghooni M., Bartels U., Lee E., Buczkowicz P., Morrison A., Huang A., Bouffet E., Hawkins C. Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets. J. Clin. Oncol. 2010, 28:1337-1344.
    • (2010) J. Clin. Oncol. , vol.28 , pp. 1337-1344
    • Zarghooni, M.1    Bartels, U.2    Lee, E.3    Buczkowicz, P.4    Morrison, A.5    Huang, A.6    Bouffet, E.7    Hawkins, C.8


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