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Volumn 8, Issue 1, 2013, Pages 34-43

Exploring genome-wide DNA methylation profiles altered in hepatocellular carcinoma using Infinium HumanMethylation 450 BeadChips

Author keywords

450K BeadChips; Alterations; DNA methylation; Genome wide; Hepatocellular carcinoma

Indexed keywords

ADULT; AGED; ARTICLE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; FEMALE; GENDER; GENETIC ASSOCIATION; HEPATITIS C; HUMAN; HUMAN TISSUE; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; RISK FACTOR;

EID: 84872016931     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.23062     Document Type: Article
Times cited : (128)

References (38)
  • 1
    • 78049485263 scopus 로고    scopus 로고
    • Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
    • PMID:21351269
    • Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010; 127:2893-917; PMID:21351269; http://dx.doi. org/10.1002/ijc.25516.
    • (2010) Int J Cancer , vol.127 , pp. 2893-2917
    • Ferlay, J.1    Shin, H.R.2    Bray, F.3    Forman, D.4    Mathers, C.5    Parkin, D.M.6
  • 2
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
    • PMID:17570226
    • El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007; 132:2557-76; PMID:17570226; http://dx.doi.org/10.1053/j.gastro.2007.04.061.
    • (2007) Gastroenterology , vol.132 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 3
    • 84855792427 scopus 로고    scopus 로고
    • Cancer statistics, 2012
    • PMID:22237781
    • Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J Clin 2012; 62:10-29; PMID:22237781; http://dx.doi.org/10.3322/ caac.20138.
    • (2012) CA Cancer J Clin , vol.62 , pp. 10-29
    • Siegel, R.1    Naishadham, D.2    Jemal, A.3
  • 4
    • 0242584454 scopus 로고    scopus 로고
    • Chromosomal instability and tumors promoted by DNA hypomethylation
    • PMID:12702868
    • Eden A, Gaudet F, Waghmare A, Jaenisch R. Chromosomal instability and tumors promoted by DNA hypomethylation. Science 2003; 300:455; PMID:12702868; http://dx.doi.org/10.1126/science.1083557.
    • (2003) Science , vol.300 , pp. 455
    • Eden, A.1    Gaudet, F.2    Waghmare, A.3    Jaenisch, R.4
  • 5
    • 41849111637 scopus 로고    scopus 로고
    • DNA methylation in hepatocellular carcinoma
    • PMID:18350605
    • Tischoff I, Tannapfe A. DNA methylation in hepatocellular carcinoma. World J Gastroenterol 2008; 14:1741-8; PMID:18350605; http://dx.doi.org/10.3748/ wjg.14.1741.
    • (2008) World J Gastroenterol , vol.14 , pp. 1741-1748
    • Tischoff, I.1    Tannapfe, A.2
  • 6
    • 80053304450 scopus 로고    scopus 로고
    • High density DNA methylation array with single CpG site resolution
    • PMID:21839163
    • Bibikova M, Barnes B, Tsan C, Ho V, Klotzle B, Le JM, et al. High density DNA methylation array with single CpG site resolution. Genomics 2011; 98:288-95; PMID:21839163; http://dx.doi.org/10.1016/j. ygeno.2011.07.007.
    • (2011) Genomics , vol.98 , pp. 288-295
    • Bibikova, M.1    Barnes, B.2    Tsan, C.3    Ho, V.4    Klotzle, B.5    Le, J.M.6
  • 7
    • 70649095120 scopus 로고    scopus 로고
    • Differential methylation of tissueand cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts
    • PMID:19881528
    • Doi A, Park IH, Wen B, Murakami P, Aryee MJ, Irizarry R, et al. Differential methylation of tissueand cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts. Nat Genet 2009; 41:1350-3; PMID:19881528; http://dx.doi.org/10.1038/ng.471.
    • (2009) Nat Genet , vol.41 , pp. 1350-1353
    • Doi, A.1    Park, I.H.2    Wen, B.3    Murakami, P.4    Aryee, M.J.5    Irizarry, R.6
  • 8
    • 59149084538 scopus 로고    scopus 로고
    • The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissue-specific CpG island shores
    • PMID:19151715
    • Irizarry RA, Ladd-Acosta C, Wen B, Wu Z, Montano C, Onyango P, et al. The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissue-specific CpG island shores. Nat Genet 2009; 41:178-86; PMID:19151715; http://dx.doi. org/10.1038/ng.298.
    • (2009) Nat Genet , vol.41 , pp. 178-186
    • Irizarry, R.A.1    Ladd-Acosta, C.2    Wen, B.3    Wu, Z.4    Montano, C.5    Onyango, P.6
  • 9
    • 84860389965 scopus 로고    scopus 로고
    • Genome-wide profiling of DNA methylation in human cancer cells
    • PMID:21821115
    • Ogoshi K, Hashimoto S, Nakatani Y, Qu W, Oshima K, Tokunaga K, et al. Genome-wide profiling of DNA methylation in human cancer cells. Genomics 2011; 98:280-7; PMID:21821115; http://dx.doi. org/10.1016/j.ygeno.2011.07.003.
    • (2011) Genomics , vol.98 , pp. 280-287
    • Ogoshi, K.1    Hashimoto, S.2    Nakatani, Y.3    Qu, W.4    Oshima, K.5    Tokunaga, K.6
  • 10
    • 53349171172 scopus 로고    scopus 로고
    • Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas
    • PMID:18632756
    • Gao W, Kondo Y, Shen L, Shimizu Y, Sano T, Yamao K, et al. Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas. Carcinogenesis 2008; 29:1901-10; PMID:18632756; http://dx.doi.org/10.1093/carcin/ bgn170.
    • (2008) Carcinogenesis , vol.29 , pp. 1901-1910
    • Gao, W.1    Kondo, Y.2    Shen, L.3    Shimizu, Y.4    Sano, T.5    Yamao, K.6
  • 11
    • 84868100147 scopus 로고    scopus 로고
    • Genome-wide analysis of DNA methylation identifies novel cancer-related genes in hepatocellular carcinoma. [Epub ahead of print]
    • PMID:21931992
    • Shitani M, Sasaki S, Akutsu N, Takagi H, Suzuki H, Nojima M, et al. Genome-wide analysis of DNA methylation identifies novel cancer-related genes in hepatocellular carcinoma. [Epub ahead of print]. Tumour Biol 2012; 33:33-40; PMID:21931992.
    • (2012) Tumour Biol , vol.33 , pp. 33-40
    • Shitani, M.1    Sasaki, S.2    Akutsu, N.3    Takagi, H.4    Suzuki, H.5    Nojima, M.6
  • 12
    • 77956607702 scopus 로고    scopus 로고
    • Identification of novel methylation markers in hepatocellular carcinoma using a methylation array
    • PMID:20676325
    • Shin SH, Kim BH, Jang JJ, Suh KS, Kang GH. Identification of novel methylation markers in hepatocellular carcinoma using a methylation array. J Korean Med Sci 2010; 25:1152-9; PMID:20676325; http:// dx.doi.org/10.3346/jkms.2010.25.8.1152.
    • (2010) J Korean Med Sci , vol.25 , pp. 1152-1159
    • Shin, S.H.1    Kim, B.H.2    Jang, J.J.3    Suh, K.S.4    Kang, G.H.5
  • 13
    • 77957361278 scopus 로고    scopus 로고
    • Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors
    • PMID:20305825
    • Hernandez-Vargas H, Lambert MP, Le Calvez-Kelm F, Gouysse G, McKay-Chopin S, Tavtigian SV, et al. Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors. PLoS One 2010; 5:e9749; PMID:20305825; http:// dx.doi.org/10.1371/journal.pone.0009749.
    • (2010) PLoS One , vol.5
    • Hernandez-Vargas, H.1    Lambert, M.P.2    Le Calvez-Kelm, F.3    Gouysse, G.4    McKay-Chopin, S.5    Tavtigian, S.V.6
  • 14
    • 84856100724 scopus 로고    scopus 로고
    • Distinct DNA methylation patterns in cirrhotic liver and hepatocellular carcinoma
    • PMID:21500188
    • Ammerpohl O, Pratschke J, Schafmayer C, Haake A, Faber W, von Kampen O, et al. Distinct DNA methylation patterns in cirrhotic liver and hepatocellular carcinoma. Int J Cancer 2012; 130:1319-28; PMID:21500188; http://dx.doi.org/10.1002/ ijc.26136.
    • (2012) Int J Cancer , vol.130 , pp. 1319-1328
    • Ammerpohl, O.1    Pratschke, J.2    Schafmayer, C.3    Haake, A.4    Faber, W.5    von Kampen, O.6
  • 15
    • 77949877704 scopus 로고    scopus 로고
    • Highthroughput assessment of CpG site methylation for distinguishing between HCV-cirrhosis and HCVassociated hepatocellular carcinoma
    • PMID:20165882
    • Archer KJ, Mas VR, Maluf DG, Fisher RA. Highthroughput assessment of CpG site methylation for distinguishing between HCV-cirrhosis and HCVassociated hepatocellular carcinoma. Mol Genet Genomics 2010; 283:341-9; PMID:20165882; http:// dx.doi.org/10.1007/s00438-010-0522-y.
    • (2010) Mol Genet Genomics , vol.283 , pp. 341-349
    • Archer, K.J.1    Mas, V.R.2    Maluf, D.G.3    Fisher, R.A.4
  • 16
    • 84861572881 scopus 로고    scopus 로고
    • Genome-wide DNA methylation profiles in hepatocellular carcinoma
    • PMID:22234943
    • Shen J, Wang S, Zhang YJ, Kappil M, Wu HC, Kibriya MG, et al. Genome-wide DNA methylation profiles in hepatocellular carcinoma. Hepatology 2012; 55:1799-808; PMID:22234943; http://dx.doi.org/10.1002/ hep.25569.
    • (2012) Hepatology , vol.55 , pp. 1799-1808
    • Shen, J.1    Wang, S.2    Zhang, Y.J.3    Kappil, M.4    Wu, H.C.5    Kibriya, M.G.6
  • 17
    • 35948981875 scopus 로고    scopus 로고
    • Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters
    • PMID:17967063
    • Shen L, Kondo Y, Guo Y, Zhang J, Zhang L, Ahmed S, et al. Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters. PLoS Genet 2007; 3:2023-36; PMID:17967063; http://dx.doi.org/10.1371/journal. pgen.0030181.
    • (2007) PLoS Genet , vol.3 , pp. 2023-2036
    • Shen, L.1    Kondo, Y.2    Guo, Y.3    Zhang, J.4    Zhang, L.5    Ahmed, S.6
  • 18
    • 79958754527 scopus 로고    scopus 로고
    • Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome
    • PMID:21593595
    • Sandoval J, Heyn HA, Moran S, Serra-Musach J, Pujana MA, Bibikova M, et al. Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome. Epigenetics 2011; 6:692-702; PMID:21593595; http://dx.doi.org/10.4161/ epi.6.6.16196.
    • (2011) Epigenetics , vol.6 , pp. 692-702
    • Sandoval, J.1    Heyn, H.A.2    Moran, S.3    Serra-Musach, J.4    Pujana, M.A.5    Bibikova, M.6
  • 19
    • 82455206314 scopus 로고    scopus 로고
    • Evaluation of the Infinium Methylation 450K technology
    • PMID:22126295
    • Dedeurwaerder S, Defrance M, Calonne E, Denis H, Sotiriou C, Fuks F. Evaluation of the Infinium Methylation 450K technology. Epigenomics 2011; 3:771-84; PMID:22126295; http://dx.doi. org/10.2217/epi.11.105.
    • (2011) Epigenomics , vol.3 , pp. 771-784
    • Dedeurwaerder, S.1    Defrance, M.2    Calonne, E.3    Denis, H.4    Sotiriou, C.5    Fuks, F.6
  • 20
    • 84862157386 scopus 로고    scopus 로고
    • Quantitative crossvalidation and content analysis of the 450k DNA methylation array from Illumina, Inc
    • PMID:22546179
    • Roessler J, Ammerpohl O, Gutwein J, Hasemeier B, Anwar SL, Kreipe HH, et al. Quantitative crossvalidation and content analysis of the 450k DNA methylation array from Illumina, Inc. BMC Res Notes 2012; 5:210; PMID:22546179; http://dx.doi. org/10.1186/1756-0500-5-210.
    • (2012) BMC Res Notes , vol.5 , pp. 210
    • Roessler, J.1    Ammerpohl, O.2    Gutwein, J.3    Hasemeier, B.4    Anwar, S.L.5    Kreipe, H.H.6
  • 21
    • 84868103364 scopus 로고    scopus 로고
    • Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans
    • PMID:22919074
    • Beyan H, Down TA, Ramagopalan SV, Uvebrant K, Nilsson A, Holland ML, et al. Guthrie card methylomics identifies temporally stable epialleles that are present at birth in humans. Genome Res 2012; 22:2138-45; PMID:22919074; http://dx.doi.org/10.1101/ gr.134304.111.
    • (2012) Genome Res , vol.22 , pp. 2138-2145
    • Beyan, H.1    Down, T.A.2    Ramagopalan, S.V.3    Uvebrant, K.4    Nilsson, A.5    Holland, M.L.6
  • 22
    • 78650058320 scopus 로고    scopus 로고
    • Evaluation of affinity-based genome-wide DNA methylation data: Effects of CpG density, amplification bias, and copy number variation
    • PMID:21045081
    • Robinson MD, Stirzaker C, Statham AL, Coolen MW, Song JZ, Nair SS, et al. Evaluation of affinity-based genome-wide DNA methylation data: effects of CpG density, amplification bias, and copy number variation. Genome Res 2010; 20:1719-29; PMID:21045081; http://dx.doi.org/10.1101/gr.110601.110.
    • (2010) Genome Res , vol.20 , pp. 1719-1729
    • Robinson, M.D.1    Stirzaker, C.2    Statham, A.L.3    Coolen, M.W.4    Song, J.Z.5    Nair, S.S.6
  • 23
    • 84859942963 scopus 로고    scopus 로고
    • Impact of the location of CpG methylation within the GSTP1 gene on its specificity as a DNA marker for hepatocellular carcinoma
    • PMID:22536438
    • Jain S, Chen S, Chang KC, Lin YJ, Hu CT, Boldbaatar B, et al. Impact of the location of CpG methylation within the GSTP1 gene on its specificity as a DNA marker for hepatocellular carcinoma. PLoS One 2012; 7:e35789; PMID:22536438; http://dx.doi. org/10.1371/journal.pone.0035789.
    • (2012) PLoS One , vol.7
    • Jain, S.1    Chen, S.2    Chang, K.C.3    Lin, Y.J.4    Hu, C.T.5    Boldbaatar, B.6
  • 24
    • 79957485296 scopus 로고    scopus 로고
    • Epigenetic mechanisms in hepatocellular carcinoma: How environmental factors influence the epigenome
    • PMID:21514401
    • Herceg Z, Paliwal A. Epigenetic mechanisms in hepatocellular carcinoma: how environmental factors influence the epigenome. Mutat Res 2011; 727:55-61; PMID:21514401; http://dx.doi.org/10.1016/j. mrrev.2011.04.001.
    • (2011) Mutat Res , vol.727 , pp. 55-61
    • Herceg, Z.1    Paliwal, A.2
  • 25
    • 77953790550 scopus 로고    scopus 로고
    • Downregulation of Gadd45beta expression by hepatitis C virus leads to defective cell cycle arrest
    • PMID:20530689
    • Higgs MR, Lerat H, Pawlotsky JM. Downregulation of Gadd45beta expression by hepatitis C virus leads to defective cell cycle arrest. Cancer Res 2010; 70:4901-11; PMID:20530689; http://dx.doi.org/10.1158/0008-5472.CAN-09-4554.
    • (2010) Cancer Res , vol.70 , pp. 4901-4911
    • Higgs, M.R.1    Lerat, H.2    Pawlotsky, J.M.3
  • 26
    • 77956978819 scopus 로고    scopus 로고
    • Detection of aberrant p16INK4A methylation in sera of patients with HCV-related liver diseases: An Egyptian study
    • PMID:20802412
    • Ahmed R, Salama H, Fouad A, Sabry D, AbdAlah S, Kamal M. Detection of aberrant p16INK4A methylation in sera of patients with HCV-related liver diseases: An Egyptian study. Med Sci Monit 2010; 16:CR410-5; PMID:20802412.
    • (2010) Med Sci Monit , vol.16
    • Ahmed, R.1    Salama, H.2    Fouad, A.3    Sabry, D.4    AbdAlah, S.5    Kamal, M.6
  • 27
    • 79955431726 scopus 로고    scopus 로고
    • Hepatitis C virus core upregulates the methylation status of the RASSF1A promoter through regulation of SMYD3 in hilar cholangiocarcinoma cells
    • PMID:21450690
    • Guo N, Chen R, Li Z, Liu Y, Cheng D, Zhou Q, et al. Hepatitis C virus core upregulates the methylation status of the RASSF1A promoter through regulation of SMYD3 in hilar cholangiocarcinoma cells. Acta Biochim Biophys Sin (Shanghai) 2011; 43:354-61; PMID:21450690; http://dx.doi.org/10.1093/abbs/ gmr021.
    • (2011) Acta Biochim Biophys Sin (Shanghai) , vol.43 , pp. 354-361
    • Guo, N.1    Chen, R.2    Li, Z.3    Liu, Y.4    Cheng, D.5    Zhou, Q.6
  • 28
    • 84862799636 scopus 로고    scopus 로고
    • Hepatitis C virus Core protein overcomes stress-induced premature senescence by down-regulating p16 expression via DNA methylation
    • PMID:22326283
    • Lim JS, Park SH, Jang KL. Hepatitis C virus Core protein overcomes stress-induced premature senescence by down-regulating p16 expression via DNA methylation. Cancer Lett 2012; 321:154-61; PMID:22326283; http://dx.doi.org/10.1016/j.canlet.2012.01.044.
    • (2012) Cancer Lett , vol.321 , pp. 154-161
    • Lim, J.S.1    Park, S.H.2    Jang, K.L.3
  • 29
    • 80052145029 scopus 로고    scopus 로고
    • Hypermethylated levels of E-cadherin promoter in Huh-7 cells expressing the HCV core protein
    • PMID:21640770
    • Ripoli M, Barbano R, Balsamo T, Piccoli C, Brunetti V, Coco M, et al. Hypermethylated levels of E-cadherin promoter in Huh-7 cells expressing the HCV core protein. Virus Res 2011; 160:74-81; PMID:21640770; http://dx.doi.org/10.1016/j.virusres.2011.05.014.
    • (2011) Virus Res , vol.160 , pp. 74-81
    • Ripoli, M.1    Barbano, R.2    Balsamo, T.3    Piccoli, C.4    Brunetti, V.5    Coco, M.6
  • 30
    • 84856204784 scopus 로고    scopus 로고
    • Global analysis of DNA methylation in early-stage liver fibrosis
    • PMID:22281153
    • Komatsu Y, Waku T, Iwasaki N, Ono W, Yamaguchi C, Yanagisawa J. Global analysis of DNA methylation in early-stage liver fibrosis. BMC Med Genomics 2012; 5:5; PMID:22281153; http://dx.doi. org/10.1186/1755-8794-5-5.
    • (2012) BMC Med Genomics , vol.5 , pp. 5
    • Komatsu, Y.1    Waku, T.2    Iwasaki, N.3    Ono, W.4    Yamaguchi, C.5    Yanagisawa, J.6
  • 31
    • 64549087538 scopus 로고    scopus 로고
    • Genes involved in viral carcinogenesis and tumor initiation in hepatitis C virus-induced hepatocellular carcinoma
    • PMID:19098997
    • Mas VR, Maluf DG, Archer KJ, Yanek K, Kong X, Kulik L, et al. Genes involved in viral carcinogenesis and tumor initiation in hepatitis C virus-induced hepatocellular carcinoma. Mol Med 2009; 15:85-94; PMID:19098997; http://dx.doi.org/10.2119/molmed.2008.00110.
    • (2009) Mol Med , vol.15 , pp. 85-94
    • Mas, V.R.1    Maluf, D.G.2    Archer, K.J.3    Yanek, K.4    Kong, X.5    Kulik, L.6
  • 32
    • 0035985214 scopus 로고    scopus 로고
    • Gene expression patterns in human liver cancers
    • PMID:12058060
    • Chen X, Cheung ST, So S, Fan ST, Barry C, Higgins J, et al. Gene expression patterns in human liver cancers. Mol Biol Cell 2002; 13:1929-39; PMID:12058060; http://dx.doi.org/10.1091/mbc.02-02-0023.
    • (2002) Mol Biol Cell , vol.13 , pp. 1929-1939
    • Chen, X.1    Cheung, S.T.2    So, S.3    Fan, S.T.4    Barry, C.5    Higgins, J.6
  • 33
    • 34247549347 scopus 로고    scopus 로고
    • Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma
    • PMID:17393520
    • Wurmbach E, Chen YB, Khitrov G, Zhang W, Roayaie S, Schwartz M, et al. Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinoma. Hepatology 2007; 45:938-47; PMID:17393520; http://dx.doi.org/10.1002/hep.21622.
    • (2007) Hepatology , vol.45 , pp. 938-947
    • Wurmbach, E.1    Chen, Y.B.2    Khitrov, G.3    Zhang, W.4    Roayaie, S.5    Schwartz, M.6
  • 34
    • 71849113808 scopus 로고    scopus 로고
    • Genome-wide DNA methylation profiles in precancerous conditions and cancers
    • PMID:19891661
    • Kanai Y. Genome-wide DNA methylation profiles in precancerous conditions and cancers. Cancer Sci 2010; 101:36-45; PMID:19891661; http://dx.doi. org/10.1111/j.1349-7006.2009.01383.x.
    • (2010) Cancer Sci , vol.101 , pp. 36-45
    • Kanai, Y.1
  • 35
    • 84865543987 scopus 로고    scopus 로고
    • Characteristic pattern of DNA methylation alterations predict emergence of human hepatocellular carcinoma
    • Nishida N, Kudo M, Nagasaka T, Ikai I, Goel A. Characteristic pattern of DNA methylation alterations predict emergence of human hepatocellular carcinoma. Hepatology 2012; 55; http://dx.doi.org/10.1002/ hep.25706.
    • (2012) Hepatology , vol.55
    • Nishida, N.1    Kudo, M.2    Nagasaka, T.3    Ikai, I.4    Goel, A.5
  • 36
    • 79959848106 scopus 로고    scopus 로고
    • Targeting insulin-like growth factor axis in hepatocellular carcinoma
    • PMID:21729319
    • Wu J, Zhu AX. Targeting insulin-like growth factor axis in hepatocellular carcinoma. J Hematol Oncol 2011; 4:30; PMID:21729319; http://dx.doi. org/10.1186/1756-8722-4-30.
    • (2011) J Hematol Oncol , vol.4 , pp. 30
    • Wu, J.1    Zhu, A.X.2
  • 37
    • 36448973787 scopus 로고    scopus 로고
    • Idiographica: A general-purpose web application to build idiograms on-demand for human, mouse and rat
    • PMID:17893084
    • Kin T, Ono Y. Idiographica: a general-purpose web application to build idiograms on-demand for human, mouse and rat. Bioinformatics 2007; 23:2945-6; PMID:17893084; http://dx.doi.org/10.1093/bioinformatics/ btm455.
    • (2007) Bioinformatics , vol.23 , pp. 2945-2946
    • Kin, T.1    Ono, Y.2
  • 38
    • 0037133565 scopus 로고    scopus 로고
    • Comprehensive analysis of CpG islands in human chromosomes 21 and 22
    • PMID:11891299
    • Takai D, Jones PA. Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc Natl Acad Sci U S A 2002; 99:3740-5; PMID:11891299; http://dx.doi.org/10.1073/pnas.052410099.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 3740-3745
    • Takai, D.1    Jones, P.A.2


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