Fatty acid metabolism in the Plasmodium apicoplast: Drugs, doubts and knockouts

Molecular and Biochemical Parasitology

Volumn 199, Issue 1-2, 2015, Pages 34-50

  Shears, Melanie J ^a,b   Botté, Cyrille Y ^a,b   McFadden, Geoffrey I ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b CNRS   (France)

Author keywords

Apicoplast; FASII; Fatty acid; Lipid; Plasmodium; Toxoplasma

Indexed keywords

3 OXOACYL ACYL CARRIER PROTEIN REDUCTASE; 3 OXOACYL ACYL CARRIER PROTEIN SYNTHASE; ACETYL COENZYME A CARBOXYLASE; ACYL CARRIER PROTEIN; FATTY ACID; GLYCEROL 3 PHOSPHATE ACYLTRANSFERASE; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; LONG CHAIN FATTY ACID COENZYME A LIGASE; MALONYL COENZYME A; PHOSPHATE TRANSPORTER; PLASTIDIC PHOSPHATE TRANSPORTER; PYRUVATE DEHYDROGENASE COMPLEX; PYRUVATE KINASE; THIOCTIC ACID; UNCLASSIFIED DRUG; ANTIMALARIAL AGENT; MALARIA VACCINE;

APICOPLAST; ARTICLE; FATTY ACID SYNTHESIS; HUMAN; MALARIA CONTROL; MALARIA FALCIPARUM; METABOLISM; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; RODENT MALARIA; SIGNAL TRANSDUCTION; SYNTHESIS; DRUG DEVELOPMENT; IMMUNOLOGY; ISOLATION AND PURIFICATION; MEDICAL RESEARCH; PLASMODIUM; TRENDS;

PLASMODIUM FALCIPARUM; RODENTIA; TOXOPLASMA;

ANTIMALARIALS; APICOPLASTS; BIOMEDICAL RESEARCH; DRUG DISCOVERY; FATTY ACIDS; MALARIA VACCINES; PLASMODIUM;

EID: 84927657225     PISSN: 01666851     EISSN: 18729428     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2015.03.004     Document Type: Review

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