A class of pantothenic acid analogs inhibits Plasmodium falciparum pantothenate kinase and represses the proliferation of malaria parasites

Antimicrobial Agents and Chemotherapy

Volumn 49, Issue 11, 2005, Pages 4649-4657

  Spry, Christina ^a   Chai, Christina L L ^c,d   Kirk, Kiaran ^a   Saliba, Kevin J ^a,b  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^b The Australian National University   (Australia)

^c AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^d INSTITUTE OF CHEMICAL AND ENGINEERING SCIENCES   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

COENZYME A; DEXPANTHENOL; ETHYL PANTOTHENOL; PANTOTHENATE KINASE; PANTOTHENIC ACID; PANTOTHENIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; DRUG ACCUMULATION; DRUG EFFICACY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HOST PARASITE INTERACTION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MALARIA FALCIPARUM; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHOSPHORYLATION; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ANIMALS; ANTIMALARIALS; ENZYME INHIBITORS; HUMANS; JURKAT CELLS; KINETICS; PANTOTHENIC ACID; PARASITIC SENSITIVITY TESTS; PHOSPHORYLATION; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 27644471425     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.49.11.4649-4657.2005     Document Type: Article

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