-
1
-
-
23344454612
-
Experimental and in silico analyses of glycolytic flux control in bloodstream form Trypanosoma brucei
-
Albert M.A., Haanstra J.R., Hannaert V., Van Roy J., Opperdoes F.R., Bakker B.M., Michels P.A. Experimental and in silico analyses of glycolytic flux control in bloodstream form Trypanosoma brucei. J. Biol. Chem. 2005, 280:28306-28315.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 28306-28315
-
-
Albert, M.A.1
Haanstra, J.R.2
Hannaert, V.3
Van Roy, J.4
Opperdoes, F.R.5
Bakker, B.M.6
Michels, P.A.7
-
2
-
-
0242298279
-
The trypanosomiases
-
Barrett M.P., Burchmore R.J., Stich A., Lazzari J.O., Frasch A.C., Cazzulo J.J., Krishna S. The trypanosomiases. Lancet. 2003, 362:1469-1480.
-
(2003)
Lancet.
, vol.362
, pp. 1469-1480
-
-
Barrett, M.P.1
Burchmore, R.J.2
Stich, A.3
Lazzari, J.O.4
Frasch, A.C.5
Cazzulo, J.J.6
Krishna, S.7
-
3
-
-
0028929650
-
Function of N-terminal import signals in trypanosome microbodies
-
Blattner J., Dorsam H., Clatyon C.E. Function of N-terminal import signals in trypanosome microbodies. FEBS Lett. 1995, 360:310-314.
-
(1995)
FEBS Lett.
, vol.360
, pp. 310-314
-
-
Blattner, J.1
Dorsam, H.2
Clatyon, C.E.3
-
4
-
-
0030031184
-
Selected novel flavones inhibit the DNA binding or the DNA religation step of eukaryotic topoisomerase I
-
Boege F., Straub T., Kehr A., Boesenberg C., Christiansen K., Andersen A., Jakob F., Kohrle J. Selected novel flavones inhibit the DNA binding or the DNA religation step of eukaryotic topoisomerase I. J. Biol. Chem. 1996, 271:2262-2270.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2262-2270
-
-
Boege, F.1
Straub, T.2
Kehr, A.3
Boesenberg, C.4
Christiansen, K.5
Andersen, A.6
Jakob, F.7
Kohrle, J.8
-
5
-
-
0037192787
-
Increased hexokinase activity, of either ectopic or endogenous origin, protects renal epithelial cells against acute oxidant-induced cell death
-
Bryson J.M., Coy P.E., Gottlob K., Hay N., Robey R.B. Increased hexokinase activity, of either ectopic or endogenous origin, protects renal epithelial cells against acute oxidant-induced cell death. J. Biol. Chem. 2002, 277:11392-11400.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11392-11400
-
-
Bryson, J.M.1
Coy, P.E.2
Gottlob, K.3
Hay, N.4
Robey, R.B.5
-
6
-
-
39049107429
-
The anti-trypanosomal agent lonidamine inhibits Trypanosoma brucei hexokinase 1
-
Chambers J.W., Fowler M.L., Morris M.T., Morris J.C. The anti-trypanosomal agent lonidamine inhibits Trypanosoma brucei hexokinase 1. Mol. Biochem. Parasitol. 2008, 158:202-207.
-
(2008)
Mol. Biochem. Parasitol.
, vol.158
, pp. 202-207
-
-
Chambers, J.W.1
Fowler, M.L.2
Morris, M.T.3
Morris, J.C.4
-
7
-
-
47249126343
-
Assembly of heterohexameric trypanosome hexokinases reveals that hexokinase 2 is a regulable enzyme
-
Chambers J.W., Kearns M.T., Morris M.T., Morris J.C. Assembly of heterohexameric trypanosome hexokinases reveals that hexokinase 2 is a regulable enzyme. J. Biol. Chem. 2008, 283:14963-14970.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 14963-14970
-
-
Chambers, J.W.1
Kearns, M.T.2
Morris, M.T.3
Morris, J.C.4
-
8
-
-
33745060757
-
Comparative proteomics of glycosomes from bloodstream form and procyclic culture form Trypanosoma brucei brucei
-
Colasante C., Ellis M., Ruppert T., Voncken F. Comparative proteomics of glycosomes from bloodstream form and procyclic culture form Trypanosoma brucei brucei. Proteomics 2006, 6:3275-3293.
-
(2006)
Proteomics
, vol.6
, pp. 3275-3293
-
-
Colasante, C.1
Ellis, M.2
Ruppert, T.3
Voncken, F.4
-
9
-
-
0020519825
-
Action of the antitumor and antispermatogenic agent lonidamine on electron transport in Ehrlich ascites tumor mitochondria
-
Floridi A., Lehninger A.L. Action of the antitumor and antispermatogenic agent lonidamine on electron transport in Ehrlich ascites tumor mitochondria. Arch. Biochem. Biophy. 1983, 226:73-83.
-
(1983)
Arch. Biochem. Biophy.
, vol.226
, pp. 73-83
-
-
Floridi, A.1
Lehninger, A.L.2
-
10
-
-
0034983918
-
Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase
-
Gottlob K., Majewski N., Kennedy S., Kandel E., Robey R.B., Hay N. Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. Genes Dev. 2001, 15:1406-1418.
-
(2001)
Genes Dev.
, vol.15
, pp. 1406-1418
-
-
Gottlob, K.1
Majewski, N.2
Kennedy, S.3
Kandel, E.4
Robey, R.B.5
Hay, N.6
-
11
-
-
0036339229
-
The ATP site of protein kinases as target for drug development: from natural compounds to gleevec
-
Granot Y. The ATP site of protein kinases as target for drug development: from natural compounds to gleevec. Isr. Med. Assoc. J. 2002, 4:633-635.
-
(2002)
Isr. Med. Assoc. J.
, vol.4
, pp. 633-635
-
-
Granot, Y.1
-
12
-
-
0017359666
-
Bioflavonoid regulation of ATPase and hexokinase activity in Ehrlich ascites cell mitochondria
-
Graziani Y. Bioflavonoid regulation of ATPase and hexokinase activity in Ehrlich ascites cell mitochondria. Biochim. Biophy. Acta 1977, 460:364-373.
-
(1977)
Biochim. Biophy. Acta
, vol.460
, pp. 364-373
-
-
Graziani, Y.1
-
13
-
-
0020635362
-
The effect of quercetin on the phosphorylation activity of the Rous sarcoma virus transforming gene product in vitro and in vivo
-
Graziani Y., Erikson E., Erikson R.L. The effect of quercetin on the phosphorylation activity of the Rous sarcoma virus transforming gene product in vitro and in vivo. Eur. J. Biochem. 1983, 135:583-589.
-
(1983)
Eur. J. Biochem.
, vol.135
, pp. 583-589
-
-
Graziani, Y.1
Erikson, E.2
Erikson, R.L.3
-
14
-
-
0035342444
-
Protein-flavonol interaction: fluorescence spectroscopic study
-
Guharay J., Sengupta B., Sengupta P.K. Protein-flavonol interaction: fluorescence spectroscopic study. Proteins 2001, 43:75-81.
-
(2001)
Proteins
, vol.43
, pp. 75-81
-
-
Guharay, J.1
Sengupta, B.2
Sengupta, P.K.3
-
15
-
-
0035922187
-
Synergistic effect of cadmium chloride and acetaldehyde on cytotoxicity and its prevention by quercetin and glycyrrhizin
-
Hu C.C., Chen W.K., Liao P.H., Yu W.C., Lee Y.J. Synergistic effect of cadmium chloride and acetaldehyde on cytotoxicity and its prevention by quercetin and glycyrrhizin. Mutat. Res. 2001, 496:117-127.
-
(2001)
Mutat. Res.
, vol.496
, pp. 117-127
-
-
Hu, C.C.1
Chen, W.K.2
Liao, P.H.3
Yu, W.C.4
Lee, Y.J.5
-
16
-
-
0034617194
-
The high resolution crystal structure of yeast hexokinase PII with the correct primary sequence provides new insights into its mechanism of action
-
Kuser P.R., Krauchenco S., Antunes O.A., Polikarpov I. The high resolution crystal structure of yeast hexokinase PII with the correct primary sequence provides new insights into its mechanism of action. J. Biol. Chem. 2000, 275:20814-20821.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 20814-20821
-
-
Kuser, P.R.1
Krauchenco, S.2
Antunes, O.A.3
Polikarpov, I.4
-
17
-
-
10744224663
-
Quercetin induces apoptosis of Trypanosoma brucei gambiense and decreases the proinflammatory response of human macrophages
-
Mamani-Matsuda M., Rambert J., Malvy D., Lejoly-Boisseau H., Daulouede S., Thiolat D., Coves S., Courtois P., Vincendeau P., Mossalayi M.D. Quercetin induces apoptosis of Trypanosoma brucei gambiense and decreases the proinflammatory response of human macrophages. Antimicrob. Agents Chemother. 2004, 48:924-929.
-
(2004)
Antimicrob. Agents Chemother.
, vol.48
, pp. 924-929
-
-
Mamani-Matsuda, M.1
Rambert, J.2
Malvy, D.3
Lejoly-Boisseau, H.4
Daulouede, S.5
Thiolat, D.6
Coves, S.7
Courtois, P.8
Vincendeau, P.9
Mossalayi, M.D.10
-
18
-
-
0034065043
-
Import of proteins into the trypanosome nucleus and their distribution at karyokinesis
-
Marchetti M.A., Tschudi C., Kwon H., Wolin S.L., Ullu E. Import of proteins into the trypanosome nucleus and their distribution at karyokinesis. J. Cell Sci. 2000, 113(Pt 5):899-906.
-
(2000)
J. Cell Sci.
, vol.113
, Issue.PART 5
, pp. 899-906
-
-
Marchetti, M.A.1
Tschudi, C.2
Kwon, H.3
Wolin, S.L.4
Ullu, E.5
-
19
-
-
0026726483
-
The inhibition of phosphatidylinositol 3-kinase by quercetin and analogs
-
Matter W.F., Brown R.F., Vlahos C.J. The inhibition of phosphatidylinositol 3-kinase by quercetin and analogs. Biochem. Biophy. Res. Commun. 1992, 186:624-631.
-
(1992)
Biochem. Biophy. Res. Commun.
, vol.186
, pp. 624-631
-
-
Matter, W.F.1
Brown, R.F.2
Vlahos, C.J.3
-
20
-
-
0021753882
-
Simultaneous purification of hexokinase, class-I fructose-bisphosphate aldolase, triosephosphate isomerase and phosphoglycerate kinase from Trypanosoma brucei
-
Misset O., Opperdoes F.R. Simultaneous purification of hexokinase, class-I fructose-bisphosphate aldolase, triosephosphate isomerase and phosphoglycerate kinase from Trypanosoma brucei. Eur. J. Biochem. 1984, 144:475-483.
-
(1984)
Eur. J. Biochem.
, vol.144
, pp. 475-483
-
-
Misset, O.1
Opperdoes, F.R.2
-
21
-
-
0034199017
-
Luteolin, an abundant dietary component is a potent anti-leishmanial agent that acts by inducing topoisomerase II-mediated kinetoplast DNA cleavage leading to apoptosis
-
Mittra B., Saha A., Chowdhury A.R., Pal C., Mandal S., Mukhopadhyay S., Bandyopadhyay S., Majumder H.K. Luteolin, an abundant dietary component is a potent anti-leishmanial agent that acts by inducing topoisomerase II-mediated kinetoplast DNA cleavage leading to apoptosis. Mol. Med. 2000, 6:527-541.
-
(2000)
Mol. Med.
, vol.6
, pp. 527-541
-
-
Mittra, B.1
Saha, A.2
Chowdhury, A.R.3
Pal, C.4
Mandal, S.5
Mukhopadhyay, S.6
Bandyopadhyay, S.7
Majumder, H.K.8
-
22
-
-
0019444723
-
Antitumor activity of flavonoids on NK/Ly ascites tumor cells
-
Molnar J., Beladi I., Domonkos K., Foldeak S., Boda K., Veckenstedt A. Antitumor activity of flavonoids on NK/Ly ascites tumor cells. Neoplasma 1981, 28:11-18.
-
(1981)
Neoplasma
, vol.28
, pp. 11-18
-
-
Molnar, J.1
Beladi, I.2
Domonkos, K.3
Foldeak, S.4
Boda, K.5
Veckenstedt, A.6
-
23
-
-
0037009442
-
Glycolysis modulates trypanosome glycoprotein expression as revealed by an RNAi library
-
Morris J.C., Wang Z., Drew M.E., Englund P.T. Glycolysis modulates trypanosome glycoprotein expression as revealed by an RNAi library. EMBO J. 2002, 21:4429-4438.
-
(2002)
EMBO J.
, vol.21
, pp. 4429-4438
-
-
Morris, J.C.1
Wang, Z.2
Drew, M.E.3
Englund, P.T.4
-
24
-
-
33845604555
-
Activity of a second Trypanosoma brucei hexokinase is controlled by an 18-amino-acid C-terminal tail
-
Morris M.T., DeBruin C., Yang Z., Chambers J.W., Smith K.S., Morris J.C. Activity of a second Trypanosoma brucei hexokinase is controlled by an 18-amino-acid C-terminal tail. Eukaryot. Cell 2006, 5:2014-2023.
-
(2006)
Eukaryot. Cell
, vol.5
, pp. 2014-2023
-
-
Morris, M.T.1
DeBruin, C.2
Yang, Z.3
Chambers, J.W.4
Smith, K.S.5
Morris, J.C.6
-
25
-
-
33745851827
-
Overexpression of a cytochrome b5 reductase-like protein causes kinetoplast DNA loss in Trypanosoma brucei
-
Motyka S.A., Drew M.E., Yildirir G., Englund P.T. Overexpression of a cytochrome b5 reductase-like protein causes kinetoplast DNA loss in Trypanosoma brucei. J. Biol. Chem. 2006, 281:18499-18506.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 18499-18506
-
-
Motyka, S.A.1
Drew, M.E.2
Yildirir, G.3
Englund, P.T.4
-
26
-
-
0024195898
-
-
The role of mitochondrial hexokinase in neoplastic phenotype and its sensitivity to lonidamine. Ann. N Y Acad. Sci.
-
Paggi, M.G., Fanciulli, M., Perrotti, N., Floridi, A., Zeuli, M., Silvestrini, B., Caputo, A., 1988. The role of mitochondrial hexokinase in neoplastic phenotype and its sensitivity to lonidamine. Ann. N Y Acad. Sci. 551, 358-360.
-
(1988)
, vol.551
, pp. 358-360
-
-
Paggi, M.G.1
Fanciulli, M.2
Perrotti, N.3
Floridi, A.4
Zeuli, M.5
Silvestrini, B.6
Caputo, A.7
-
27
-
-
0036434544
-
The interaction of quercetin with human serum albumin: a fluorescence spectroscopic study
-
Sengupta B., Sengupta P.K. The interaction of quercetin with human serum albumin: a fluorescence spectroscopic study. Biochem. Biophy.Res. Commun. 2002, 299:400-403.
-
(2002)
Biochem. Biophy.Res. Commun.
, vol.299
, pp. 400-403
-
-
Sengupta, B.1
Sengupta, P.K.2
-
28
-
-
77952409132
-
A target-based high throughput screen yields Trypanosoma brucei hexokinase small molecule inhibitors with antiparasitic activity
-
Sharlow E.R., Lyda T.A., Dodson H.C., Mustata G., Morris M.T., Leimgruber S.S., Lee K.H., Kashiwada Y., Close D., Lazo J.S., Morris J.C. A target-based high throughput screen yields Trypanosoma brucei hexokinase small molecule inhibitors with antiparasitic activity. PLoS Neglected Tropical Diseases 2010, 4:e659.
-
(2010)
PLoS Neglected Tropical Diseases
, vol.4
-
-
Sharlow, E.R.1
Lyda, T.A.2
Dodson, H.C.3
Mustata, G.4
Morris, M.T.5
Leimgruber, S.S.6
Lee, K.H.7
Kashiwada, Y.8
Close, D.9
Lazo, J.S.10
Morris, J.C.11
-
29
-
-
0022249093
-
Inhibition of phosphorylase kinase, and tyrosine protein kinase activities by quercetin
-
Srivastava A.K. Inhibition of phosphorylase kinase, and tyrosine protein kinase activities by quercetin. Biochem. Biophy. Res. Commun. 1985, 131:1-5.
-
(1985)
Biochem. Biophy. Res. Commun.
, vol.131
, pp. 1-5
-
-
Srivastava, A.K.1
-
30
-
-
0016821736
-
The effect of flavonoids on aerobic glycolysis and growth of tumor cells
-
Suolinna E.M., Buchsbaum R.N., Racker E. The effect of flavonoids on aerobic glycolysis and growth of tumor cells. Cancer Res. 1975, 35:1865-1872.
-
(1975)
Cancer Res.
, vol.35
, pp. 1865-1872
-
-
Suolinna, E.M.1
Buchsbaum, R.N.2
Racker, E.3
-
31
-
-
0034704084
-
Inhibition of Trypanosoma brucei gene expression by RNA interference using an integratable vector with opposing T7 promoters
-
Wang Z., Morris J.C., Drew M.E., Englund P.T. Inhibition of Trypanosoma brucei gene expression by RNA interference using an integratable vector with opposing T7 promoters. J. Biol. Chem. 2000, 275:40174-40179.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 40174-40179
-
-
Wang, Z.1
Morris, J.C.2
Drew, M.E.3
Englund, P.T.4
-
32
-
-
0035990006
-
Sequencing, modeling, and selective inhibition of Trypanosoma brucei hexokinase
-
Willson M., Sanejouand Y.H., Perie J., Hannaert V., Opperdoes F. Sequencing, modeling, and selective inhibition of Trypanosoma brucei hexokinase. Chem. Biol. 2002, 9:839-847.
-
(2002)
Chem. Biol.
, vol.9
, pp. 839-847
-
-
Willson, M.1
Sanejouand, Y.H.2
Perie, J.3
Hannaert, V.4
Opperdoes, F.5
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