Inhibiting enoyl-ACP reductase (FabI) across pathogenic microorganisms by linear sesquiterpene lactones from Anthemis auriculata

Phytomedicine

Volumn 15, Issue 12, 2008, Pages 1125-1129

  Karioti, Anastasia ^a   Skaltsa, Helen ^a   Zhang, Xujie ^b   Tonge, Peter J ^b   Perozzo, Remo ^c   Kaiser, Marcel ^d   Franzblau, Scott G ^e   Tasdemir, Deniz ^f  

^a UNIVERSITY OF ATHENS   (Greece)

^b STONY BROOK UNIVERSITY   (United States)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^e UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^f UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Anthecotulide; Anthemis auriculata; Escherichia coli; FabI; Fatty acid biosynthesis; Mycobacterium tuberculosis; Plasmodium falciparum; Sesquiterpene lactone

Indexed keywords

3 OXOACYL ACYL CARRIER PROTEIN REDUCTASE; 4 ACETOXYANTHECOTULIDE; 4 HYDROXYANTHECOTULIDE; ANTHECOTULIDE; BETA HYDROXYACYL ACYL CARRIER PROTEIN DEYDRATASE; ENOYL ACYL CARRIER PROTEIN REDUCTASE (NADPH); ENZYME; SESQUITERPENE LACTONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTHEMIS; ANTHEMIS AURICULATA; ANTIBACTERIAL ACTIVITY; ANTIMALARIAL ACTIVITY; ARTICLE; CELL ASSAY; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; ENZYME INHIBITION; ESCHERICHIA COLI; IC 50; MICROORGANISM; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; WHOLE CELL;

ANIMALS; ANTHEMIS; ANTI-BACTERIAL AGENTS; ANTIMALARIALS; BACTERIAL PROTEINS; ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (NADH); ENZYME INHIBITORS; ESCHERICHIA COLI; LACTONES; MYCOBACTERIUM TUBERCULOSIS; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; SESQUITERPENES;

ANTHEMIS; ESCHERICHIA COLI; MYCOBACTERIUM TUBERCULOSIS; PLASMODIUM FALCIPARUM;

EID: 56249091778     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2008.02.018     Document Type: Article

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