Structural insights into the acyl intermediates of the Plasmodium falciparum fatty acid synthesis pathway. The mechanism of expansion of the acyl carrier protein core

Journal of Biological Chemistry

Volumn 284, Issue 33, 2009, Pages 22390-22400

  Upadhyay, Santosh Kumar ^a   Misra, Ashish ^b   Srivastava, Richa ^b   Surolia, Namita ^c   Surolia, Avadhesha ^a,b   Sundd, Monica ^a  

^a JAWAHARLAL NEHRU UNIVERSITY   (India)

^b INDIAN INSTITUTE OF SCIENCE   (India)

^c JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CARRIER PROTEINS; ACYL CHAIN; ACYL-ACP; CHARGE-CHARGE REPULSION; CHEMICAL SHIFT PERTURBATIONS; CONFORMATIONAL CHANGE; CONSERVED RESIDUES; ELECTROSTATIC REPULSION; FATTY ACID BIOSYNTHESIS; FATTY ACID SYNTHESIS; HYDROPHOBIC CAVITIES; HYDROPHOBIC CORE; LONG RANGE; MODEL COMPOUND; MOLECULAR MACHINERY; MOLECULAR MECHANISM; NUCLEAR OVERHAUSER EFFECTS; PLASMODIUM FALCIPARUM; PROSTHETIC GROUPS; SIDE CHAINS; SPECTROSCOPIC PROBES; STRUCTURAL INSIGHTS; STRUCTURAL RESTRAINTS; STRUCTURAL STUDIES;

ACIDS; AMIDES; BIOCHEMISTRY; CARBOXYLATION; CHEMICAL SHIFT; COMPLEXATION; CONFORMATIONS; FATTY ACIDS; HYDROGEN; HYDROGEN BONDS; HYDROPHOBICITY; MECHANISMS; NUCLEAR MAGNETIC RESONANCE; PROTEINS;

CLUSTERING ALGORITHMS;

ACYL CARRIER PROTEIN; CARBOXYLIC ACID;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL MODIFICATION; CONFORMATIONAL TRANSITION; FATTY ACID SYNTHESIS; HYDROGEN BOND; MOLECULAR MECHANICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN STRUCTURE;

ACYL CARRIER PROTEIN; ANIMALS; CLONING, MOLECULAR; FATTY ACIDS; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PLASMODIUM FALCIPARUM; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; STATIC ELECTRICITY;

PLASMODIUM FALCIPARUM;

EID: 69249111810     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.014829     Document Type: Article

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