Identification and functional analysis of the primary pantothenate transporter, PfPAT, of the human malaria parasite Plasmodium falciparum

Journal of Biological Chemistry

Volumn 288, Issue 28, 2013, Pages 20558-20567

  Augagneur, Yoann ^a   Jaubert, Lise ^a   Schiavoni, Matthieu ^a   Pachikara, Niseema ^a   Garg, Aprajita ^a   Usmani Brown, Sahar ^a   Wesolowski, Donna ^b   Zeller, Skye ^a   Ghosal, Abhisek ^c   Cornillot, Emmanuel ^d   Said, Hamid M ^c   Kumar, Priti ^a   Altman, Sidney ^b   Ben Mamoun, Choukri ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIV MONTPELLIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL DRUG; BIOCHEMICAL PROPERTIES; FUNCTIONAL CHARACTERIZATION; GENETIC ANALYSIS; HUMAN ERYTHROCYTES; HUMAN MALARIA PARASITE; MOLECULAR IDENTITIES; PLASMODIUM FALCIPARUM;

CELL MEMBRANES; YEAST;

DISEASES;

ANTIMALARIAL AGENT; CARRIER PROTEIN; CHLOROQUINE; FENPROPIMORPH; PANTOTHENATE TRANSPORTER; PANTOTHENIC ACID; PANTOTHENIC ACID DERIVATIVE; PYRIMETHAMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIMALARIAL DRUG RESISTANCE; ARTICLE; CELL MEMBRANE; CHEMICAL ANALYSIS; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; DRUG TARGETING; DRUG TRANSPORT; FUNGUS MUTANT; GENETIC ANALYSIS; GENETIC STRAIN; GROWTH INHIBITION; HOST; HUMAN; HUMAN CELL; NONHUMAN; PARASITE DEVELOPMENT; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTEIN TARGETING; YEAST;

DRUG DELIVERY; MALARIA; PLASMODIUM; TRANSPORT; YEAST;

AMINO ACID SEQUENCE; ANIMALS; ANTIMALARIALS; CELL MEMBRANE; CHLOROQUINE; DRUG RESISTANCE; ERYTHROCYTES; GENETIC COMPLEMENTATION TEST; HEK293 CELLS; HOST-PARASITE INTERACTIONS; HUMANS; MALARIA, FALCIPARUM; MICROSCOPY, FLUORESCENCE; MICROSCOPY, IMMUNOELECTRON; MOLECULAR SEQUENCE DATA; MORPHOLINES; MUTATION; PANTOTHENIC ACID; PHYLOGENY; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; PYRIMETHAMINE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SYMPORTERS;

EID: 84880061742     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.482992     Document Type: Article

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