SAR and pharmacophore models for the rhodanine inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase

IUBMB Life

Volumn 62, Issue 3, 2010, Pages 204-213

  Kumar, Gyanendra ^a   Banerjee, Tanushree ^a   Kapoor, Neha ^a   Surolia, Namita ^b   Surolia, Avadhesha ^a  

^a NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

^b JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

Author keywords

Drug design; Inhibitors; Pharmacophores; Rhodanines; Structure activity relationships

Indexed keywords

BENZENE DERIVATIVE; ENOYL ACYL CARRIER PROTEIN REDUCTASE (NADH); FURAN; RHODANINE;

ARTICLE; COMPUTER MODEL; HYDROGEN BOND; HYDROPHOBICITY; IC 50; NONHUMAN; PHARMACOPHORE; PLASMODIUM FALCIPARUM; STRUCTURE ACTIVITY RELATION;

ANTIMALARIALS; DRUG DESIGN; ENOYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (NADH); HYDROGEN BONDING; INHIBITORY CONCENTRATION 50; PLASMODIUM FALCIPARUM; RHODANINE; STRUCTURE-ACTIVITY RELATIONSHIP;

PLASMODIUM FALCIPARUM;

EID: 77951112326     PISSN: 15216543     EISSN: 15216551     Source Type: Journal    
DOI: 10.1002/iub.306     Document Type: Article

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