Synthesis and evaluation of substituted pyrazoles: Potential antimalarials targeting the enoyl-ACP reductase of Plasmodium Falciparum

Synthetic Communications

Volumn 36, Issue 2, 2006, Pages 215-226

  Kumar, Sanjay ^a   Kumar, Gyanendra ^a   Kapoor, Mili ^a   Surolia, Avadhesha ^a   Surolia, Namita ^b  

^a INDIAN INSTITUTE OF SCIENCE   (India)

^b JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH   (India)

Author keywords

Antimalarials; Fatty acid synthesis; Inhibitor; Substituted pyrazole

Indexed keywords

4 [5 (4 NITROPHENYL) 3 (TRIFLUOROMETHYL) 1H PYRAZOLE 1YL]BENZENSULFONAMIDE; 5 (4 NITROPHENYL) 3 (TRIFLUOROMETHYL) 1 (3 CHLOR 4 FLUOROPHENYL)PYRAZOLE; 5 (4 NITROPHENYL) 3 (TRIFLUOROMETHYL) 1 (4 CHLOROPHENYL)PYRAZOLE; 5 (4 NITROPHENYL) 3 (TRIFLUOROMETHYL) 1 [4 TRIFLUOROMETHYL (2 PYRIMIDYL)]PYRAZOLE; 5 (4 NITROPHENYL) 3 (TRIFLUOROMETHYL) 1 PHENYLPYRAZOLE; PYRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG MECHANISM; DRUG SYNTHESIS; ENZYME INHIBITION; EVALUATION; NONHUMAN; PLASMODIUM FALCIPARUM; SPECTROPHOTOMETRY; SUBSTITUTION REACTION;

EID: 31144454663     PISSN: 00397911     EISSN: 15322432     Source Type: Journal    
DOI: 10.1080/00397910500334561     Document Type: Article

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