Nutrient and nonnutrient components of legumes, and its chemopreventive activity: A review

Nutrition and Cancer

Volumn 67, Issue 3, 2015, Pages 401-410

  Sánchez Chino, Xariss ^a   Jiménez Martínez, Cristian ^a   Dávila Ortiz, Gloria ^a   Álvarez González, Isela ^a   Madrigal Bujaidar, Eduardo ^a  

^a INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLASE; CARBOHYDRATE; ESSENTIAL AMINO ACID; ISOFLAVONE DERIVATIVE; LECTIN; PHENOL DERIVATIVE; PHYTATE; PROTEIN INHIBITOR; SAPONIN; ANTINEOPLASTIC AGENT; PHYTIC ACID; PLANT LECTIN; VEGETABLE PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BEAN; CANCER INCIDENCE; CHEMOPROPHYLAXIS; COLON CANCER; COLORECTAL CANCER; COTYLEDON; FAT CONTENT; HEREDITY; HUMAN; LEGUME; LENTIL; NONHUMAN; NUTRIENT CONTENT; NUTRITIONAL REQUIREMENT; SOYBEAN; CHEMISTRY; FABACEAE; PHYTOTHERAPY;

ANIMALIA; GLYCINE MAX; LENS CULINARIS;

ALPHA-AMYLASES; ANTICARCINOGENIC AGENTS; FABACEAE; ISOFLAVONES; PHENOLS; PHYTIC ACID; PHYTOTHERAPY; PLANT LECTINS; PLANT PROTEINS;

EID: 84926516244     PISSN: 01635581     EISSN: 15327914     Source Type: Journal    
DOI: 10.1080/01635581.2015.1004729     Document Type: Article

References (97)

1. McPhee K and Muehlbauer F: Improving the nutritional value of cool season food legumes. J Crop Prod 5, 191-211, 2002.
2. Jenkins DJA, Kendall CWC, Augustin LSA, Mitchell S, Sahye-Pudaruth S, et al.: Effect of legumes as part of a low glycemic index diet on glycemic control and cardiovascular risk factors in type 2 diabetes mellitus: a randomized controlled trial. Arch Intern Med 172, 1653-1660, 2012.
3. Tharanathan R and Mahadevamma S: Grain legumes-A boon to human nutrition. Trends Food Sci Tech 14, 507-518, 2003.
4. Guillon F and Champ M-J: Carbohydrate fractions of legumes: uses in human nutrition and potential for health. Brit J Nut 88, 293-306, 2002.
5. Alajaji SA and El-Adawy TA: Nutritional composition of chickpea (Cicer arietinum L.) as affected by microwave cooking and other traditional cooking methods. J Food Compos Anal 19, 806-812, 2006.
6. Friedman M and Brandon DL: Nutritional and health benefits of soy proteins. J Agric Food Chem 49, 1069-1086, 2001.
7. Edwards C: Interactions between nutrition and the intestinal microflora. Proceedings of the Nutrition Society 52, 375-382, 1993.
8. Muzquiz M and Wood J: 6 antinutritional factors. In: Chickpea Breeding and Management, Yadav SS, Redden RJ, Chen W, and Cabi SB (eds). UK: CABI, 2007, 143-166.
9. Muzquiz M, Varela A, Burbano C, Cuadrado C, Guillam-on E, et al.: Bioactive compounds in legumes: Pronutritive and antinutritive actions. implications for nutrition and health. Phytochem Rev 11, 227-244, 2012.
10. Sangronis E, Torres A, and Sanabria N: a-galact-osidos y fitatos en semilla germinadas de Phaseolus vulgaris y de Vigna sinensis. Agronom-?a Trop 56, 523-529, 2006.
11. Reza A, Abdolmajid H, Abbas M, and Abdolmohammad AK: Effect of dietary prebiotic inulin on growth performance, intestinal microflora, body composition and hematological parameters of juvenile beluga, Huso huso (Linnaeus, 1758). J World Aquac Soc 40, 771-779, 2009.
12. Duranti M: Grain legume proteins and nutraceutical properties. Fitoterapia 77, 67-82, 2006.
13. Segura-Nieto M and Jim-enez-Flores R: Genetic modifications of plant seed storage proteins for food production. In: Molecular Biotechnology for Plant Food Production, Paredes-Lopez O (ed). Lancaster, PA: Technomic Publishing, 1999, 411-492.
14. Hood-Niefer SD, Warkentin TD, Chibbar RN, Vandenberg A, and Tyler RT: Effect of genotype and environment on the concentrations of starch and protein in, and the physicochemical properties of starch from, field pea and fababean. J Sci Food Agric 92, 141-150, 2012.
15. Aguilar OL, Vega ES, Lugo IB, and Rebolledo H: Pinole de alto valor nutricional obtenido a partir de cereales y leguminosas. Ra Ximhai 4, 283-294, 2008.
16. Brillouet JM and Riochet D: Cell wall polysaccharides and lignin in cotyledons and hulls of seeds from various lupin (Lupinus L.) species. J Sci Food Agric 34, 861-868, 1983.
17. Thumad Al-Kaisey M and Wilkie KC: The polysaccharides of agricultural lupin seeds. Carbohyd Res 227, 147-161, 1992.
18. Petterson D, Gladstones J, Atkins C, and Hamblin J: Composition and food uses of lupins. In: Lupins as Crop Plants: biology, production and utilization, Gladstones JS, Atkins CA, and Hamblin J (eds). CAB International Pub, 1998, 353-384.
19. Kaur M, Singh N, and Sodhi NS: Physicochemical, cooking, textural and roasting characteristics of chickpea (Cicer arietinum L.) cultivars. J Food Eng 69, 511-517, 2005.
20. Kummerow FA, Mahfouz M, Zhou Q, and Masterjohn C: Effects of trans fats on prostacyclin production. Scand Cardiovasc J 47, 377-382, 2013.
21. FAO: Human vitamin and mineral requirement. Report of a joint FAO/WHO expert consultation, Bangkok, Thailand. Retrieved from http://www.fao.org/DOCREP/004/Y2809E/y2809e00.html
22. Quinteros A, Farr-e R, and Lagarda MJ: Optimization of iron speciation (soluble, ferrous and ferric) in beans, chickpeas and lentils. Food Chem 75, 365-370, 2001.
23. U.S. Department of Agriculture: USDA National Nutrient Database for Standard Reference, Release Retrieved from http://wwwnalusdagov/fnic/foodcomp/search/
24. Wink M: Evolution of secondary metabolites in legumes (Fabaceae). S Afr J Bot, 89, 164-175, 2013.
25. Dixon RA and Paiva NL: Stress-induced phenylpropanoid metabolism. Plant Cell 7, 1085-1097, 1995.
26. Griffiths DW: The polyphenolic content and enzyme inhibitory activity of testas from bean (Vicia faba) and pea (Pisum spp.) varieties. J Sci Food Agric 32, 797-804, 1981.
27. Heiras-Palazuelos MJ, Ochoa-Lugo MI, Guti-errez-Dorado R, L-opez-Valenzuela JA, Mora-Roch-?n S, et al.: Technological properties, antioxidant activity and total phenolic and flavonoid content of pigmented chickpea (Cicer arietinum L.) cultivars. International. J Food Sci Nutr 64, 69-76, 2013.
28. Cardador-Mart-?nez A, Loarca-Piña G, and Oomah BD: Antioxidant activity in common beans (Phaseolus vulgaris L.). J Agric Food Chem 50, 6975-6980, 2002.
29. Beninger CW and Hosfield GL: Antioxidant activity of extracts, condensed tannin fractions, and pure flavonoids from Phaseolus vulgaris L. seed coat color genotypes. J Agric Food Chem 51, 7879-7883, 2003. doi:10.1021/jf0304324
30. Luthria DL and Pastor-Corrales MA: Phenolic acids content of fifteen dry edible bean (Phaseolus vulgaris L.) varieties. J Food Compos Anal 19, 205-211, 2006.
31. Oomah BD, Corb-e Al, and Balasubramanian P: Antioxidant and antiinflammatory activities of bean (Phaseolus vulgaris L.) hulls. J Agric Food Chem 58, 8225-8230, 2010.
32. Ross K, Beta T, and Arntfield S: A comparative study on the phenolic acids identified and quantified in dry beans using HPLC as affected by different extraction and hydrolysis methods. Food Chemistry113, 336-344, 2009.
33. Nithiyanantham S, Selvakumar S, and Siddhuraju P: Total phenolic content and antioxidant activity of two different solvent extracts from raw and processed legumes, Cicer arietinum L. and Pisum sativum L. J Food Compos Anal 27, 52-60, 2012.
34. McDougall GJ and Stewart D: The inhibitory effects of berry polyphenols on digestive enzymes. Biofactors 23, 189-195, 2005.
35. Ranilla LG, Kwon YI, Genovese MI, Lajolo F, and Shetty K: Effect of thermal treatment on phenolic compounds and functionality linked to type 2 diabetes and hypertension management of Peruvian and Brazilian bean cultivars (Phaseolus vulgaris L.) using in vitro methods. J Food Biochem 34, 329-355, 2010.
36. Halina L and Sharon N: Biological properties of lectins. In: The Lectins: Properties, Functions, and Applications in Biology and Medicine (Molecular Biology), Lienes I, Sharon N, and Golstein I (eds). Orlando, FL: Academic Press, 1986, 266-285.
37. Liener IE: Implications of antinutritional components in soybean foods. Crit Rev Food Sci Nutr 34, 31-67, 1994.
38. Barrueto-Gonzalez NB: Biodisponibilidade de minerais das fontes leguminosas. Rev Simbio-Logias 1, 174-183, 2008.
39. Sparg S, Light M, and Van Staden J: Biological activities and distribution of plant saponins. J Ethnopharmacol 94, 219-243, 2004.
40. Johnson IT, Gee JM, Price K, Curl C, and Fenwick GR: Influence of saponins on gut permeability and active nutrient transport in vitro. J Nutr 116, 2270-2277, 1986.
41. Rimbach G and Pallauf J: Cadmium accumulation, zinc status, and mineral bioavailability of growing rats fed diets high in zinc with increasing amounts of phytic acid. Biol Trace Elem Res 57, 59-70, 1997.
42. Wati RK, Theppakorn T, Benjakul S, and Rawdkuen S: Trypsin inhibitor from 3 legume seeds: Fractionation and proteolytic inhibition study. J Food Sci 75, C223-C228, 2010.
43. Ryan CA: Protease inhibitors in plants: genes for improving defenses against insects and pathogens. Annu Rev Phytopathol 28, 425-449, 1990.
44. Hathcock JN: Residue trypsin inhibitor: data needs for risk assessment. Adv Exp Med Biol 289, 273-279, 1990.
45. Lajolo FM and Genovese MI: Nutritional significance of lectins and enzyme inhibitors from legumes. J Agric Food Chem 50, 6592-6598, 2002.
46. Malkowicz SB, McKenna WG, Vaughn DJ, Wan XS, Propert KJ, et al.: Effects of Bowman-Birk inhibitor concentrate (BBIC) in patients with benign prostatic hyperplasia. Prostate 48, 16-28, 2001.
47. DeClerck YA and Imren S: Protease inhibitors: Role and potential therapeutic use in human cancer. Europ J Cancer 30, 2170-2180, 1994.
48. Hocman G: Chemoprevention of cancer: protease inhibitors. Inter J Biochem 24, 1365-1375, 1992. http://dx.doi.org/10.1016/0020-711X(92) 90061-5
49. Dong J-Y and Qin L-Q: Soy isoflavones consumption and risk of breast cancer incidence or recurrence: a meta-Analysis of prospective studies. Breast Cancer Res Tr 125, 315-323, 2011.
50. Gee JM, Price KR, Ridout CL, Johnson IT, and Fenwick GR: Effects of some purified saponins on transmural potential difference in mammalian small intestine. Toxicol in Vitro 3, 85-90, 1989.
51. Gurfinkel DM and Rao AV: Soyasaponins: the relationship between chemical structure and colon anticarcinogenic activity. Nutr Cancer 47, 24-33, 2003. doi:10.1207/s15327914nc4701-3
52. Arellano Ortiz A, Rodrigo Garc-?a J, and L-opez D-?az J: Evaluaci-on del efecto hipocolesterolemiante de productos de soya. Ciencia en la Frontera 165, 165-172, 2008.
53. Sidhu GS and Oakenfull DG: A mechanism for the hypocholesterolaemic activity of saponins. British J Nutr 55, 643-649, 1986.
54. Rao AV and Sung MK: Saponins as anticarcinogens. J Nutr 125, 717S-724S, 1995.
55. Ludueña B, Mastandrea C, Chichizola C, and Franconi MC: Isoflavonas en soja, contenido de daidze-?na y geniste-?na y su importancia biol-ogica. Bioqu-?mica y Patolog-?a Cl-?nica 71, 54-66, 2007.
56. Li F, Fernandez PP, Rajendran P, Hui KM, and Sethi G: Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells. Cancer Lett 292, 197-207, 2010.
57. Cho KM, Ha TJ, Lee YB, Seo WD, Kim JY, et al.: Soluble phenolics and antioxidant properties of soybean (Glycine max L.) cultivars with varying seed coat colours. J Funct Foods 5, 1065-1076, 2013.
58. Corbiere C, Liagre B, Terro F, and Beneytout JL: Induction of antiproliferative effect by diosgenin through activation of p53, release of apoptosis-inducing factor (AIF) and modulation of caspase-3 activity in different human cancer cells. Cell Res 14, 188-196, 2004.
59. Liagre B, Vergne-Salle P, Corbiere C, Charissoux JL, and Beneytout JL: Diosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpression. Arthritis Res Ther 6, R373-R383, 2004.
60. Hermsdorff HHM, Zulet M-A, Abete I, and Mart-?nez JA: A legumebased hypocaloric diet reduces proinflammatory status and improves metabolic features in overweight/obese subjects. Europ J Nutr 50, 61-69, 2011.
61. Zhu Z, Jiang W, and Thompson HJ: Edible dry bean consumption (Phaseolus vulgaris L.) modulates cardiovascular risk factors and diet-induced obesity in rats and mice. Brit J Nutr 108, S66-S73, 2012.
62. Crujeiras AB, Goyenechea E, and Martinez JA: Fruit, vegetables and legumes consumption: Role in preventing and treating obesity. In: Bioactive Foods in Promoting Health: Fruits and Vegetables, Watson RR and Preedy VR (eds). Amsterdam, The Netherlands: Academic Press, 2010, 359-380.
63. Macarulla MT, Medina C, De Diego MA, Ch-Avarri M, Zulet MA, et al.: Effects of the whole seed and a protein isolate of faba bean (Vicia faba) on the cholesterol metabolism of hypercholesterolaemic rats. British J Nutr 85, 607-614, 2001.
64. Garrido G A, De La Maza C MP, and Valladares BL: Potential health benefits of phytoestrogens. Fitoestr-ogenos dietarios y sus potenciales beneficios en la salud del adulto humano. Rev Med Chile 131, 1321-1328, 2003.
65. Boualga A, Prost J, Taleb-Senouci D, Krouf D, Kharoubi O, et al.: Purified chickpea or lentil proteins impair VLDL metabolism and lipoprotein lipase activity in epididymal fat, but not in muscle, compared to casein, in growing rats. Europ J Nutr 48, 162-169, 2009.
66. Hutchins AM, Winham DM, and Thompson SV: Phaseolus beans: Impact on glycaemic response and chronic disease risk in human subjects. Brit J Nutr 108, S52-S65, 2012.
67. Esmaillzadeh A and Azadbakht L: Legume consumption is inversely associated with serum concentrations of adhesion molecules and inflammatory biomarkers among Iranian women. J Nutr 142, 334-339, 2012.
68. Hughes JS, Ganthavorn C, and Wilson-Sanders S: Dry beans inhibit azoxymethane-induced colon carcinogenesis in F344 rats. J Nutr 127, 2328-2333, 1997.
69. Hangen L and Bennink MR: Consumption of black beans and navy beans (Phaseolus vulgaris) reduced azoxymethane-induced colon cancer in rats. Nutr Cancer 44, 60-65, 2002.
70. Murillo G, Choi JK, Pan O, Constantinou AI, and Mehta RG: Efficacy of garbanzo and soybean flour in suppression of aberrant crypt foci in the colons of CF-1 mice. Anticancer Res 24, 3049-3055, 2004.
71. Faris MAIE, Takruri HR, Shomaf MS, and Bustanji YK: Chemopreventive effect of raw and cooked lentils (Lens culinaris L) and soybeans (Glycine max) against azoxymethane-induced aberrant crypt foci. Nutr Res 29, 355-362, 2009.
72. Mathers JC: Pulses and carcinogenesis: Potential for the prevention of colon, breast and other cancers. Brit J Nutr 88, S273-S279, 2002.
73. Valko M, Rhodes C, Moncol J, Izakovic M, and Mazur M: Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem Biol Interac 160, 1-40, 2006.
74. Trueba GP, S-Anchez GM, and Giuliani A: Oxygen free radical and antioxidant defense mechanism in cancer. Front Biosci 9, 2029-2044, 2004.
75. Krzystyniak KL: Current strategies for anticancer chemoprevention and chemoprotection. Acta Pol Pharm 59, 473-478, 2002.
76. Ricci-Vitiani L, Lombardi DG, Pilozzi E, Biffoni M, Todaro M, et al.: Identification and expansion of human colon-cancer-initiating cells. Nature 445, 111-115, 2007.
77. Rajamanickam S and Agarwal R: Natural products and colon cancer: Current status and future prospects. Drug Develop Res 69, 460-471, 2008.
78. Bird RP: Role of aberrant crypt foci in understanding the pathogenesis of colon cancer. Cancer Lett 93, 55-71, 1995. http://dx.doi.org/10.1016/0304-3835(95)03788-X
79. Raju J: Azoxymethane-induced rat aberrant crypt foci: Relevance in studying chemoprevention of colon cancer. World J Gastroentero 14, 6632-6635, 2008.
80. Torruco-Uco J, Chel-Guerrero L, Mart-?nez-Ayala A, D-Avila-Ort-?z G, and Betancur-Ancona D: Angiotensin-I converting enzyme inhibitory and antioxidant activities of protein hydrolysates from Phaseolus lunatus and Phaseolus vulgaris seeds. LWT Food Sci Tech 42, 1597-1604, 2009.
81. Bobe G, Barrett KG, Mentor-Marcel RA, Saffiotti U, Young MR, et al.: Dietary cooked navy beans and their fractions attenuate colon carcinogenesis in azoxymethane-induced ob/ob mice. Nutr Cancer 60, 373-381, 2008.
82. Hayd-e VC, Ram-on G-G, Lorenzo GO, Dave OB, Rosal-?a RC, et al.: Nondigestible fraction of beans (Phaseolus vulgaris L.) modulates signalling pathway genes at an early stage of colon cancer in Sprague-Dawley rats. Brit J Nutr 108, S145-S154, 2012.
83. Murillo G, Choi UK, Pan O, Constantinou AI, and Mehta RG: Efficacy of garbanzo and soybean flour in suppression of aberrant crypt foci in the colons of CF-1 mice. Anticancer Res 24, 3049-3056, 2004.
84. Rao AV and Koratkar R: Anticarcinogenic Effects of saponins and phytosterols. In: Antinutrients and Phytochemicals in Food, Shahidi F (eds), ACS Symposium Series. Wageningen, Netherlands: Wageningen Academic Publishers, 1997, 313-324.
85. Faris MeA-IE, Takruri HR, Shomaf MS, and Bustanji YK: Chemopreventive effect of raw and cooked lentils (Lens culinaris L) and soybeans (Glycine max) against azoxymethane-induced aberrant crypt foci. Nutr Res 29, 355-362, 2009.
86. Jordinson M, El-Hariry I, Calnan D, Calam J, and Pignatelli M: Vicia faba agglutinin, the lectin present in broad beans, stimulates differentiation of undifferentiated colon cancer cells. Gut 44, 709-714, 1999.
87. Madar Z and Stark AH: New legume sources as therapeutic agents. Brit J Nutr 88, S287-S292, 2002.
88. Thompson MD, Thompson HJ, Brick MA, McGinley JN, Jiang W, et al.: Mechanisms associated with dose-dependent inhibition of rat mammary carcinogenesis by dry bean (Phaseolus vulgaris, L.). J Nutr 138, 2091-2097, 2008.
89. Thompson MD and Thompson HJ: Physiological effects of bean (Phaseolus vulgaris L.) consumption on cellular signaling in cancer. Cell Cycle 11, 835-836, 2012.
90. Messina MJ: Legumes and soybeans: Overview of their nutritional profiles and health effects. Am J Clin Nutr 70, 439S-450S, 1999.
91. Nagaraju GP, Zafar SF, and El-Rayes BF: Pleiotropic effects of genistein in metabolic, inflammatory, and malignant diseases. Nutr Rev 71, 562-572, 2013.
92. Lamartiniere CA, Cotroneo MS, Fritz WA, Wang J, Mentor-Marcel R, et al.: Genistein chemoprevention: timing and mechanisms of action in murine mammary and prostate. J Nutr 132, 552S-558S, 2002.
93. Hasler CM: Functional foods: their role in disease prevention and health promotion. Food Tech 52, 63-147, 1998.
94. Robles-Ram-?rez MDC, Ram-on-Gallegos E, Reyes-Duarte FJ, and Mora-Escobedo R: Effect of germinated soy protein on the growth of HeLa cervical cancer cells in female athymic mice. Nutr Cancer 64, 1261-1268, 2012.
95. Wang Y, Wang Z, Fu L, Chen Y, and Fang J: Legume consumption and colorectal adenoma risk: a meta-Analysis of observational studies. PLoS ONE 8, e67335, 2013.
96. Hamilton-Reeves JM, Banerjee S, Banerjee SK, Holzbeierlein JM, Thrasher JB, et al.: Short-term soy isoflavone intervention in patients with localized prostate cancer: a randomized, double-blind, placebo-controlled trial. PLoS One 8, e68331, 2013.
97. Fechner A, Fenske K, and Jahreis G: Effects of legume kernel fibres and citrus fibre on putative risk factors for colorectal cancer: a randomised, double-blind, crossover human intervention trial. Nutr J 12, 101, 2013. doi:10.1186/1475-2891-12-101