Induction of antiproliferative effect by diosgenin through activation of p53, release of apoptosis-inducing factor (AIF) and modulation of caspase-3 activity in different human cancer cells

Cell Research

Volumn 14, Issue 3, 2004, Pages 188-196

  Corbiere, Cecile ^a   Liagre, Bertrand ^a   Terro, Faraj ^a   Beneytout, Jean Louis ^a  

^a UNIVERSITY OF LIMOGES   (France)

Author keywords

AIF; Apoptosis; Cancer cells; Caspase; Diosgenin; p53

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASP3 PROTEIN, HUMAN; CASPASE; CASPASE 3; DIOSGENIN; DNA FRAGMENT; FLAVOPROTEIN; MEMBRANE PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PDCD8 PROTEIN, HUMAN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

ARTICLE; CELL CYCLE; CELL DIVISION; DRUG EFFECT; HUMAN; INTRACELLULAR MEMBRANE; LARYNX TUMOR; MELANOMA; METABOLISM; MITOCHONDRION; PHYSIOLOGY; TUMOR CELL LINE;

APOPTOSIS INDUCING FACTOR; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASES; CELL CYCLE; CELL DIVISION; CELL LINE, TUMOR; DIOSGENIN; DNA FRAGMENTATION; FLAVOPROTEINS; HUMANS; INTRACELLULAR MEMBRANES; LARYNGEAL NEOPLASMS; MELANOMA; MEMBRANE PROTEINS; MITOCHONDRIA; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 8844280276     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/sj.cr.7290219     Document Type: Article

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