Genistein chemoprevention: Timing and mechanisms of action in murine mammary and prostate

Journal of Nutrition

Volumn 132, Issue 3, 2002, Pages

  Lamartiniere, Coral A ^a,b   Cotroneo, Michelle S ^a   Fritz, Wayne A ^a   Wang, Jun ^a   Mentor Marcel, Roycelynn ^c   Elgavish, Ada ^b,c  

^a Department of Pharmacology and Toxicology ^*  (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Cancer; Chemoprevention; Genistein; Mammary; Prostate

Indexed keywords

ANDROGEN RECEPTOR; DIMETHYLBENZ[A]ANTHRACENE; EPIDERMAL GROWTH FACTOR RECEPTOR; ESTROGEN RECEPTOR ALPHA; GENISTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; NITROSOUREA DERIVATIVE; PROGESTERONE RECEPTOR; SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; BREAST CANCER; CELL DIFFERENTIATION; CHEMOPROPHYLAXIS; CONFERENCE PAPER; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; MALE; MAMMARY GLAND; NONHUMAN; PROSTATE; PROSTATE CANCER; RAT; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

ANIMALIA; MURINAE; MUS MUSCULUS;

EID: 0036195968     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/132.3.552s     Document Type: Conference Paper

References (57)

1. Breast cancer in women after repeated fluoroscopic examinations of the chest
2. Breast cancer incidence among atomic bomb survivors: Implications for radiobiologic risk at low doses
3. Breast cancer: Magnitude of the problem and descriptive epidemiology
4. N-nitroso-N-methylurea-induced mammary carcinogenesis: Effect of pregnancy on preneoplastic cells
5. Chemoprevention of N-nitroso-N-methylurea-induced mammary cancers by pretreatment with 17β-estradiol and progesterone
6. Dietary effects on breast cancer risk in Singapore
7. Migration patterns and breast cancer risk in Asian-American women
8. Urinary excretion of lignins and isoflavonoid phytoestrogens in Japanese men and women consuming a traditional diet
9. Steroid and phyto-estrogen binding to sheep uterine receptors in vitro
10. Binding of phytoestrogens and estradiol-17β by cytoplasmic receptors in the pituitary gland and hypothalamus of the ewe
11. Phytoestrogen interaction with estrogen receptors in human breast cells
12. Dietary estrogens act through estrogen receptor-mediated processes and show no antiestrogenicity in cultured breast cancer cells
13. Estrogenic activity of isoflavone derivative extracted and prepared for soybean oil meal
14. Relative potencies of several estrogen-like compounds found in forages
15. The interaction in the immature mouse of potent estrogens with coumestrol, genistein and other uterovaginotrophic compounds of low potency
16. Effect of genistein on topoisomerase activity and on the growth of [VAL12] Ha-ras-transformed NIH 3T3 cells
17. Involvement of tyrosine and protein kinase C in platelet-activating-factorinduced c-fos gene expression in A-421 cells
18. Genistein, a specific inhibitor of tyrosine-specific protein kinases
19. Effects of the tyrosine-kinase inhibitor genistein on DNA synthesis and phospholipid-induced second messenger generation in mouse 10T1/2 fibroblasts and rat liver T51B cells
20. Inhibition of in vitro microsomal lipid peroxidation by isoflavonoids
21. Genistein, a dietary-derived inhibitor of in vitro angiogenesis
22. Antioxidants isolated from fermented soybeans (tempeh)
23. Phenolic antioxidants of soy protein hydrolysates
24. Antioxidant and antipromotional effects of the soybean isoflavone genistein
25. Induction of in vitro differentiation of mouse erythroleukemia cells by genistein, an inhibitor of tyrosine protein kinases
26. Increased neurite out-growth induced by inhibition of protein tyrosine kinase activity in PC12 pheochromocytoma cells
27. Dietary genistein: Perinatal mammary cancer prevention, bioavailability and toxicity testing in the rat
28. Genistein: Mammary cancer chemoprevention, in vivo mechanisms of action, potential for toxicity, and bioavailability in rats
29. Genistein suppresses mammary cancer in rats
30. Prepubertal genistein exposure suppresses mammary cancer and enhances gland differentiation in rats
31. Prepubertal exposure to zearalenone or genistein reduces mammary tumorigenesis
32. Maternal exposure to genistein during pregnancy increases carcinogen-induced mammary tumorigenesis in female rat offspring
33. Pharmacologic, but not dietary genistein supports endometriosis in a rat model
34. Soyfood intake during adolescence and subsequent risk of breast cancer among Chinese women
35. Developmental stage of the rat mammary gland as determinant of its susceptibility to 7, 12-dimethylbenz(a)anthracene
36. Susceptibility of the mammary gland to carcinogenesis I: Differentiation of the mammary gland as determinant of tumor incidence and type of lesion
37. Prepubertal genistein treatment modulates TGF-α, EGF and EGF-receptor mRNAs and proteins in the rat mammary gland
38. The neuroendocrine regulation of sexual behavior
39. Interactions between hormones and nerve tissue
40. Organizational effects of hormones and hormonally-active xenobiotics on postnatal development
41. Phytoestrogens: Epidemiology and a possible role in cancer protection
42. Implications of stromal-epithetial interaction in human prostate cancer growth, progression and differentiation
43. Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County
44. Plasma concentrations of phytoestrogens in Japanese men
45. Diet and its preventive role in prostatic disease
46. Dietary genistein suppresses chemically-induced prostate cancer in Lobund-Wistar Rats
47. Prostate cancer in a transgenic mouse
48. A transgenic mouse prostate cancer model
49. Androgen-independent prostate cancer progression in the TRAMP model
50. Genistein in the diet reduces the incidence of prostate tumors in a transgenic mouse (TRAMP)
51. The endocrinology and developmental biology of the prostate
52. Longitudinal cohort analysis of lethal prostate cancer progression in transgenic mice
53. The insulin-like growth factor axis and prostate cancer: Lessons from transgenic adenocarcinoma of mouse prostate (TRAMP) model
54. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptor alpha and beta
55. Estrogen receptor transcription and transactivation: Basic aspects of estrogen action
56. Genistein, a component of soy, inhibits the expression of the EGF and ErbB/Neu receptors in the rat dorsolateral prostate