-
1
-
-
84884934084
-
Brain regional cannabinoid CB(1) receptor signalling and alternative enzymatic pathways for 2-arachidonoylglycerol generation in brain sections of diacylglycerol lipase deficient mice
-
Aaltonen, N., Riera Ribas, C., Lehtonen, M., Savinainen, J. R., and Laitinen, J. T. (2014). Brain regional cannabinoid CB(1) receptor signalling and alternative enzymatic pathways for 2-arachidonoylglycerol generation in brain sections of diacylglycerol lipase deficient mice. Eur. J. Pharm. Sci. 51, 87-95. doi: 10.1016/j.ejps.2013.08.035
-
(2014)
Eur. J. Pharm. Sci.
, vol.51
, pp. 87-95
-
-
Aaltonen, N.1
Riera Ribas, C.2
Lehtonen, M.3
Savinainen, J.R.4
Laitinen, J.T.5
-
2
-
-
34347342722
-
Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors
-
Agarwal, N., Pacher, P., Tegeder, I., Amaya, F., Constantin, C. E., Brenner, G. J.,et al. (2007). Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors. Nat. Neurosci. 10, 870-879. doi: 10.1038/nn1916
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 870-879
-
-
Agarwal, N.1
Pacher, P.2
Tegeder, I.3
Amaya, F.4
Constantin, C.E.5
Brenner, G.J.6
-
3
-
-
44849141696
-
Enzymatic pathways that regulate endocannabinoid signaling in the nervous system
-
Ahn, K., Mckinney, M. K., and Cravatt, B. F. (2008). Enzymatic pathways that regulate endocannabinoid signaling in the nervous system. Chem. Rev. 108, 1687-1707. doi: 10.1021/cr0782067
-
(2008)
Chem. Rev.
, vol.108
, pp. 1687-1707
-
-
Ahn, K.1
Mckinney, M.K.2
Cravatt, B.F.3
-
4
-
-
33745960208
-
Antinociceptive and hypothermic effects of salvinorin a are abolished in a novel strain of kappa-opioid receptor-1 knockout mice
-
Ansonoff, M. A., Zhang, J., Czyzyk, T., Rothman, R. B., Stewart, J., Xu, H.,et al. (2006). Antinociceptive and hypothermic effects of salvinorin a are abolished in a novel strain of kappa-opioid receptor-1 knockout mice. J. Pharmacol. Exp. Ther. 318, 641-648. doi: 10.1124/jpet.106.101998
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.318
, pp. 641-648
-
-
Ansonoff, M.A.1
Zhang, J.2
Czyzyk, T.3
Rothman, R.B.4
Stewart, J.5
Xu, H.6
-
5
-
-
84886668594
-
Responses to novelty and vulnerability to cocaine addiction: contribution of a multi-symptomatic animal model
-
Belin, D., and Deroche-Gamonet, V. (2012). Responses to novelty and vulnerability to cocaine addiction: contribution of a multi-symptomatic animal model. Cold Spring Harb. Perspect. Med. 2:a011940. doi: 10.1101/cshperspect.a011940.
-
(2012)
Cold Spring Harb. Perspect. Med
, vol.2
-
-
Belin, D.1
Deroche-Gamonet, V.2
-
6
-
-
77649185404
-
Bimodal control of stimulated food intake by the endocannabinoid system
-
Bellocchio, L., Lafenetre, P., Cannich, A., Cota, D., Puente, N., Grandes, P.,et al. (2010). Bimodal control of stimulated food intake by the endocannabinoid system. Nat. Neurosci. 13, 281-283. doi: 10.1038/nn.2494
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 281-283
-
-
Bellocchio, L.1
Lafenetre, P.2
Cannich, A.3
Cota, D.4
Puente, N.5
Grandes, P.6
-
7
-
-
84875247295
-
Activation of the sympathetic nervous system mediates hypophagic and anxiety-like effects of CB(1) receptor blockade
-
Bellocchio, L., Soria-Gomez, E., Quarta, C., Metna-Laurent, M., Cardinal, P., Binder, E.,et al. (2013). Activation of the sympathetic nervous system mediates hypophagic and anxiety-like effects of CB(1) receptor blockade. Proc. Natl. Acad. Sci. U.S.A. 110, 4786-4791. doi: 10.1073/pnas.1218573110
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 4786-4791
-
-
Bellocchio, L.1
Soria-Gomez, E.2
Quarta, C.3
Metna-Laurent, M.4
Cardinal, P.5
Binder, E.6
-
8
-
-
1642422411
-
Cannabinoid receptor and WIN 55 212-2-stimulated [35S]-GTPgammaS binding in the brain of mu-, delta-, and kappa-opioid receptor knockout mice
-
Berrendero, F., Mendizabal, V., Murtra, P., Kieffer, B. L., and Maldonado, R. (2003). Cannabinoid receptor and WIN 55 212-2-stimulated [35S]-GTPgammaS binding in the brain of mu-, delta-, and kappa-opioid receptor knockout mice. Eur. J. Neurosci. 18, 2197-2202. doi: 10.1046/j.1460-9568.2003.02951.x
-
(2003)
Eur. J. Neurosci.
, vol.18
, pp. 2197-2202
-
-
Berrendero, F.1
Mendizabal, V.2
Murtra, P.3
Kieffer, B.L.4
Maldonado, R.5
-
9
-
-
84908519175
-
Endogenous opiates and behavior: 2013
-
Bodnar, R. J. (2014). Endogenous opiates and behavior: 2013. Peptides 62C, 67-136. doi: 10.1016/j.peptides.2014.09.013
-
(2014)
Peptides
, vol.62 C
, pp. 67-136
-
-
Bodnar, R.J.1
-
10
-
-
0033532375
-
Region-specific up-regulation of opioid receptor binding in enkephalin knockout mice
-
Brady, L. S., Herkenham, M., Rothman, R. B., Partilla, J. S., Konig, M., Zimmer, A. M.,et al. (1999). Region-specific up-regulation of opioid receptor binding in enkephalin knockout mice. Brain Res. Mol. Brain Res. 68, 193-197. doi: 10.1016/S0169-328X(99)00090-X
-
(1999)
Brain Res. Mol. Brain Res.
, vol.68
, pp. 193-197
-
-
Brady, L.S.1
Herkenham, M.2
Rothman, R.B.3
Partilla, J.S.4
Konig, M.5
Zimmer, A.M.6
-
11
-
-
0034685707
-
Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB(2) receptor
-
Buckley, N. E., Mccoy, K. L., Mezey, E., Bonner, T., Zimmer, A., Felder, C. C.,et al. (2000). Immunomodulation by cannabinoids is absent in mice deficient for the cannabinoid CB(2) receptor. Eur. J. Pharmacol. 396, 141-149. doi: 10.1016/S0014-2999(00)00211-9
-
(2000)
Eur. J. Pharmacol.
, vol.396
, pp. 141-149
-
-
Buckley, N.E.1
Mccoy, K.L.2
Mezey, E.3
Bonner, T.4
Zimmer, A.5
Felder, C.C.6
-
12
-
-
84871343938
-
Dimerization with cannabinoid receptors allosterically modulates delta opioid receptor activity during neuropathic pain
-
Bushlin, I., Gupta, A., Stockton, S. D. Jr., Miller, L. K., and Devi, L. A. (2012). Dimerization with cannabinoid receptors allosterically modulates delta opioid receptor activity during neuropathic pain. PLoS ONE 7:e49789. doi: 10.1371/journal.pone.0049789
-
(2012)
PLoS ONE
, vol.7
-
-
Bushlin, I.1
Gupta, A.2
Stockton, S.D.3
Miller, L.K.4
Devi, L.A.5
-
13
-
-
0037232392
-
Cannabinoid withdrawal syndrome is reduced in double mu and delta opioid receptor knockout mice
-
Castane, A., Robledo, P., Matifas, A., Kieffer, B. L., and Maldonado, R. (2003). Cannabinoid withdrawal syndrome is reduced in double mu and delta opioid receptor knockout mice. Eur. J. Neurosci. 17, 155-159. doi: 10.1046/j.1460-9568.2003.02409.x
-
(2003)
Eur. J. Neurosci.
, vol.17
, pp. 155-159
-
-
Castane, A.1
Robledo, P.2
Matifas, A.3
Kieffer, B.L.4
Maldonado, R.5
-
14
-
-
78649924956
-
Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system
-
Chanda, P. K., Gao, Y., Mark, L., Btesh, J., Strassle, B. W., Lu, P.,et al. (2010). Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system. Mol. Pharmacol. 78, 996-1003. doi: 10.1124/mol.110.068304
-
(2010)
Mol. Pharmacol.
, vol.78
, pp. 996-1003
-
-
Chanda, P.K.1
Gao, Y.2
Mark, L.3
Btesh, J.4
Strassle, B.W.5
Lu, P.6
-
15
-
-
84887071742
-
15 years of genetic approaches in vivo for addiction research: opioid receptor and peptide gene knockout in mouse models of drug abuse
-
Charbogne, P., Kieffer, B. L., and Befort, K. (2014). 15 years of genetic approaches in vivo for addiction research: opioid receptor and peptide gene knockout in mouse models of drug abuse. Neuropharmacology 76(Pt B), 204-217. doi: 10.1016/j.neuropharm.2013.08.028
-
(2014)
Neuropharmacology
, vol.76
, pp. 204-217
-
-
Charbogne, P.1
Kieffer, B.L.2
Befort, K.3
-
16
-
-
84922559775
-
A novel anxiogenic role for the delta opioid receptor expressed in GABAergic forebrain neurons
-
[Epub ahead of print].
-
Chu Sin Chung, P., Keyworth, H. L., Martin-Garcia, E., Charbogne, P., Darcq, E., Bailey, A.,et al. (2014). A novel anxiogenic role for the delta opioid receptor expressed in GABAergic forebrain neurons. Biol. Psychiatry doi: 10.1016/j.biopsych.2014.07.033 [Epub ahead of print].
-
(2014)
Biol. Psychiatry
-
-
Chu Sin Chung, P.1
Keyworth, H.L.2
Martin-Garcia, E.3
Charbogne, P.4
Darcq, E.5
Bailey, A.6
-
17
-
-
18744390307
-
Autoradiography of opioid and ORL1 ligands in opioid receptor triple knockout mice
-
Clarke, S., Czyzyk, T., Ansonoff, M., Nitsche, J. F., Hsu, M. S., Nilsson, L.,et al. (2002). Autoradiography of opioid and ORL1 ligands in opioid receptor triple knockout mice. Eur. J. Neurosci. 16, 1705-1712. doi: 10.1046/j.1460-9568.2002.02239.x
-
(2002)
Eur. J. Neurosci.
, vol.16
, pp. 1705-1712
-
-
Clarke, S.1
Czyzyk, T.2
Ansonoff, M.3
Nitsche, J.F.4
Hsu, M.S.5
Nilsson, L.6
-
18
-
-
0242403121
-
Region selective up-regulation of micro-, delta- and kappa-opioid receptors but not opioid receptor-like 1 receptors in the brains of enkephalin and dynorphin knockout mice
-
Clarke, S., Zimmer, A., Zimmer, A. M., Hill, R. G., and Kitchen, I. (2003). Region selective up-regulation of micro-, delta- and kappa-opioid receptors but not opioid receptor-like 1 receptors in the brains of enkephalin and dynorphin knockout mice. Neuroscience 122, 479-489. doi: 10.1016/j.neuroscience.2003.07.011
-
(2003)
Neuroscience
, vol.122
, pp. 479-489
-
-
Clarke, S.1
Zimmer, A.2
Zimmer, A.M.3
Hill, R.G.4
Kitchen, I.5
-
19
-
-
2942577559
-
Mu opioid receptor: a gateway to drug addiction
-
Contet, C., Kieffer, B. L., and Befort, K. (2004). Mu opioid receptor: a gateway to drug addiction. Curr. Opin. Neurobiol. 14, 370-378. doi: 10.1016/j.conb.2004.05.005
-
(2004)
Curr. Opin. Neurobiol.
, vol.14
, pp. 370-378
-
-
Contet, C.1
Kieffer, B.L.2
Befort, K.3
-
20
-
-
0035824948
-
Cannabinoid CB1 receptor knockout mice fail to self-administer morphine but not other drugs of abuse
-
Cossu, G., Ledent, C., Fattore, L., Imperato, A., Bohme, G. A., Parmentier, M.,et al. (2001). Cannabinoid CB1 receptor knockout mice fail to self-administer morphine but not other drugs of abuse. Behav. Brain Res. 118, 61-65. doi: 10.1016/S0166-4328(00)00311-9
-
(2001)
Behav. Brain Res.
, vol.118
, pp. 61-65
-
-
Cossu, G.1
Ledent, C.2
Fattore, L.3
Imperato, A.4
Bohme, G.A.5
Parmentier, M.6
-
21
-
-
0035979244
-
Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase
-
Cravatt, B. F., Demarest, K., Patricelli, M. P., Bracey, M. H., Giang, D. K., Martin, B. R.,et al. (2001). Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. Proc. Natl. Acad. Sci. U.S.A. 98, 9371-9376. doi: 10.1073/pnas.161191698
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 9371-9376
-
-
Cravatt, B.F.1
Demarest, K.2
Patricelli, M.P.3
Bracey, M.H.4
Giang, D.K.5
Martin, B.R.6
-
22
-
-
0029904838
-
Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides
-
Cravatt, B. F., Giang, D. K., Mayfield, S. P., Boger, D. L., Lerner, R. A., and Gilula, N. B. (1996). Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides. Nature 384, 83-87. doi: 10.1038/384083a0
-
(1996)
Nature
, vol.384
, pp. 83-87
-
-
Cravatt, B.F.1
Giang, D.K.2
Mayfield, S.P.3
Boger, D.L.4
Lerner, R.A.5
Gilula, N.B.6
-
23
-
-
3242710172
-
Functional disassociation of the central and peripheral fatty acid amide signaling systems
-
Cravatt, B. F., Saghatelian, A., Hawkins, E. G., Clement, A. B., Bracey, M. H., and Lichtman, A. H. (2004). Functional disassociation of the central and peripheral fatty acid amide signaling systems. Proc. Natl. Acad. Sci. U.S.A. 101, 10821-10826. doi: 10.1073/pnas.0401292101
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 10821-10826
-
-
Cravatt, B.F.1
Saghatelian, A.2
Hawkins, E.G.3
Clement, A.B.4
Bracey, M.H.5
Lichtman, A.H.6
-
24
-
-
84893782140
-
Targeted expression of mu-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward
-
Cui, Y., Ostlund, S. B., James, A. S., Park, C. S., Ge, W., Roberts, K. W.,et al. (2014). Targeted expression of mu-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward. Nat. Neurosci. 17, 254-261. doi: 10.1038/nn.3622
-
(2014)
Nat. Neurosci.
, vol.17
, pp. 254-261
-
-
Cui, Y.1
Ostlund, S.B.2
James, A.S.3
Park, C.S.4
Ge, W.5
Roberts, K.W.6
-
25
-
-
84876931006
-
Epigenetic mechanisms and endocannabinoid signalling
-
D'Addario, C., Di Francesco, A., Pucci, M., Finazzi Agro, A., and Maccarrone, M. (2013). Epigenetic mechanisms and endocannabinoid signalling. FEBS J. 280, 1905-1917. doi: 10.1111/febs.12125
-
(2013)
FEBS J.
, vol.280
, pp. 1905-1917
-
-
D'Addario, C.1
Di Francesco, A.2
Pucci, M.3
Finazzi Agro, A.4
Maccarrone, M.5
-
26
-
-
84909951309
-
Endocannabinoid 2-arachidonoylglycerol self-administration by sprague-dawley rats and stimulation of in vivo dopamine transmission in the nucleus accumbens Shell
-
De Luca, M. A., Valentini, V., Bimpisidis, Z., Cacciapaglia, F., Caboni, P., and Di Chiara, G. (2014). Endocannabinoid 2-arachidonoylglycerol self-administration by sprague-dawley rats and stimulation of in vivo dopamine transmission in the nucleus accumbens Shell. Front. Psychiatry 5:140. doi: 10.3389/fpsyt.2014.00140
-
(2014)
Front. Psychiatry
, vol.5
, pp. 140
-
-
De Luca, M.A.1
Valentini, V.2
Bimpisidis, Z.3
Cacciapaglia, F.4
Caboni, P.5
Di Chiara, G.6
-
27
-
-
77249107540
-
Non-CB1, non-CB2 receptors for endocannabinoids, plant cannabinoids, and synthetic cannabimimetics: focus on G-protein-coupled receptors and transient receptor potential channels
-
De Petrocellis, L., and Di Marzo, V. (2010). Non-CB1, non-CB2 receptors for endocannabinoids, plant cannabinoids, and synthetic cannabimimetics: focus on G-protein-coupled receptors and transient receptor potential channels. J. Neuroimmune Pharmacol. 5, 103-121. doi: 10.1007/s11481-009-9177-z
-
(2010)
J. Neuroimmune Pharmacol.
, vol.5
, pp. 103-121
-
-
De Petrocellis, L.1
Di Marzo, V.2
-
28
-
-
84907466163
-
CB2 cannabinoid receptors as a therapeutic target-what does the future hold?
-
Dhopeshwarkar, A., and Mackie, K. (2014). CB2 cannabinoid receptors as a therapeutic target-what does the future hold? Mol. Pharmacol. 86, 430-437. doi: 10.1124/mol.114.094649
-
(2014)
Mol. Pharmacol.
, vol.86
, pp. 430-437
-
-
Dhopeshwarkar, A.1
Mackie, K.2
-
29
-
-
0033769188
-
Levels, metabolism, and pharmacological activity of anandamide in CB(1) cannabinoid receptor knockout mice: evidence for non-CB(1), non-CB(2) receptor-mediated actions of anandamide in mouse brain
-
Di Marzo, V., Breivogel, C. S., Tao, Q., Bridgen, D. T., Razdan, R. K., Zimmer, A. M.,et al. (2000). Levels, metabolism, and pharmacological activity of anandamide in CB(1) cannabinoid receptor knockout mice: evidence for non-CB(1), non-CB(2) receptor-mediated actions of anandamide in mouse brain. J. Neurochem. 75, 2434-2444. doi: 10.1046/j.1471-4159.2000.0752434.x
-
(2000)
J. Neurochem.
, vol.75
, pp. 2434-2444
-
-
Di Marzo, V.1
Breivogel, C.S.2
Tao, Q.3
Bridgen, D.T.4
Razdan, R.K.5
Zimmer, A.M.6
-
30
-
-
0036678094
-
Brain monoglyceride lipase participating in endocannabinoid inactivation
-
Dinh, T. P., Carpenter, D., Leslie, F. M., Freund, T. F., Katona, I., Sensi, S. L.,et al. (2002). Brain monoglyceride lipase participating in endocannabinoid inactivation. Proc. Natl. Acad. Sci. U.S.A. 99, 10819-10824. doi: 10.1073/pnas.152334899
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 10819-10824
-
-
Dinh, T.P.1
Carpenter, D.2
Leslie, F.M.3
Freund, T.F.4
Katona, I.5
Sensi, S.L.6
-
31
-
-
84857125716
-
Cannabinoid type 1 receptors located on single-minded 1-expressing neurons control emotional behaviors
-
Dubreucq, S., Kambire, S., Conforzi, M., Metna-Laurent, M., Cannich, A., Soria-Gomez, E.,et al. (2012a). Cannabinoid type 1 receptors located on single-minded 1-expressing neurons control emotional behaviors. Neuroscience 204, 230-244. doi: 10.1016/j.neuroscience.2011.08.049
-
(2012)
Neuroscience
, vol.204
, pp. 230-244
-
-
Dubreucq, S.1
Kambire, S.2
Conforzi, M.3
Metna-Laurent, M.4
Cannich, A.5
Soria-Gomez, E.6
-
32
-
-
84862323196
-
Genetic dissection of the role of cannabinoid type-1 receptors in the emotional consequences of repeated social stress in mice
-
Dubreucq, S., Matias, I., Cardinal, P., Haring, M., Lutz, B., Marsicano, G.,et al. (2012b). Genetic dissection of the role of cannabinoid type-1 receptors in the emotional consequences of repeated social stress in mice. Neuropsychopharmacology 37, 1885-1900. doi: 10.1038/npp.2012.36
-
(2012)
Neuropsychopharmacology
, vol.37
, pp. 1885-1900
-
-
Dubreucq, S.1
Matias, I.2
Cardinal, P.3
Haring, M.4
Lutz, B.5
Marsicano, G.6
-
33
-
-
84895775893
-
A mu-delta opioid receptor brain atlas reveals neuronal co-occurrence in subcortical networks
-
[Epub ahead of print].
-
Erbs, E., Faget, L., Scherrer, G., Matifas, A., Filliol, D., Vonesch, J. L.,et al. (2014). A mu-delta opioid receptor brain atlas reveals neuronal co-occurrence in subcortical networks. Brain Struct. Funct. doi: 10.1007/s00429-014-0717-9 [Epub ahead of print].
-
(2014)
Brain Struct. Funct.
-
-
Erbs, E.1
Faget, L.2
Scherrer, G.3
Matifas, A.4
Filliol, D.5
Vonesch, J.L.6
-
34
-
-
0027050144
-
Cloning of a delta opioid receptor by functional expression
-
Evans, C. J., Keith, D. E. Jr., Morrison, H., Magendzo, K., and Edwards, R. H. (1992). Cloning of a delta opioid receptor by functional expression. Science 258, 1952-1955. doi: 10.1126/science.1335167
-
(1992)
Science
, vol.258
, pp. 1952-1955
-
-
Evans, C.J.1
Keith, D.E.2
Morrison, H.3
Magendzo, K.4
Edwards, R.H.5
-
35
-
-
27644454882
-
Neural systems of reinforcement for drug addiction: from actions to habits to compulsion
-
Everitt, B. J., and Robbins, T. W. (2005). Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nat. Neurosci. 8, 1481-1489. doi: 10.1038/nn1579
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 1481-1489
-
-
Everitt, B.J.1
Robbins, T.W.2
-
36
-
-
0034941981
-
Intravenous self-administration of the cannabinoid CB1 receptor agonist WIN 55,212-2 in rats
-
Fattore, L., Cossu, G., Martellotta, C. M., and Fratta, W. (2001). Intravenous self-administration of the cannabinoid CB1 receptor agonist WIN 55,212-2 in rats. Psychopharmacology (Berl) 156, 410-416. doi: 10.1007/s002130100734
-
(2001)
Psychopharmacology (Berl)
, vol.156
, pp. 410-416
-
-
Fattore, L.1
Cossu, G.2
Martellotta, C.M.3
Fratta, W.4
-
37
-
-
19444374853
-
Endocannabinoid system and opioid addiction: behavioural aspects
-
Fattore, L., Deiana, S., Spano, S. M., Cossu, G., Fadda, P., Scherma, M.,et al. (2005). Endocannabinoid system and opioid addiction: behavioural aspects. Pharmacol. Biochem. Behav. 81, 343-359. doi: 10.1016/j.pbb.2005.01.031
-
(2005)
Pharmacol. Biochem. Behav.
, vol.81
, pp. 343-359
-
-
Fattore, L.1
Deiana, S.2
Spano, S.M.3
Cossu, G.4
Fadda, P.5
Scherma, M.6
-
38
-
-
84855507862
-
Beyond THC: the new generation of cannabinoid designer drugs
-
Fattore, L., and Fratta, W. (2011). Beyond THC: the new generation of cannabinoid designer drugs. Front. Behav. Neurosci. 5:60. doi: 10.3389/fnbeh.2011.00060
-
(2011)
Front. Behav. Neurosci
, vol.5
, pp. 60
-
-
Fattore, L.1
Fratta, W.2
-
39
-
-
77952170829
-
Cannabinoid-dopamine interaction in the pathophysiology and treatment of CNS disorders
-
Fernandez-Ruiz, J., Hernandez, M., and Ramos, J. A. (2010). Cannabinoid-dopamine interaction in the pathophysiology and treatment of CNS disorders. CNS Neurosci. Ther. 16, e72-e91. doi: 10.1111/j.1755-5949.2010.00144.x
-
(2010)
CNS Neurosci. Ther.
, vol.16
, pp. e72-e91
-
-
Fernandez-Ruiz, J.1
Hernandez, M.2
Ramos, J.A.3
-
40
-
-
77952640781
-
Adenosine-cannabinoid receptor interactions. Implications for striatal function
-
Ferre, S., Lluis, C., Justinova, Z., Quiroz, C., Orru, M., Navarro, G.,et al. (2010). Adenosine-cannabinoid receptor interactions. Implications for striatal function. Br. J. Pharmacol. 160, 443-453. doi: 10.1111/j.1476-5381.2010.00723.x
-
(2010)
Br. J. Pharmacol.
, vol.160
, pp. 443-453
-
-
Ferre, S.1
Lluis, C.2
Justinova, Z.3
Quiroz, C.4
Orru, M.5
Navarro, G.6
-
41
-
-
84871802310
-
Grand opening of structure-guided design for novel opioids
-
Filizola, M., and Devi, L. A. (2014). Grand opening of structure-guided design for novel opioids. Trends Pharmacol. Sci. 34, 6-12. doi: 10.1016/j.tips.2012.10.002
-
(2014)
Trends Pharmacol. Sci.
, vol.34
, pp. 6-12
-
-
Filizola, M.1
Devi, L.A.2
-
42
-
-
16744364787
-
Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses
-
Filliol, D., Ghozland, S., Chluba, J., Martin, M., Matthes, H. W., Simonin, F.,et al. (2000). Mice deficient for delta- and mu-opioid receptors exhibit opposing alterations of emotional responses. Nat. Genet. 25, 195-200. doi: 10.1038/76061
-
(2000)
Nat. Genet.
, vol.25
, pp. 195-200
-
-
Filliol, D.1
Ghozland, S.2
Chluba, J.3
Martin, M.4
Matthes, H.W.5
Simonin, F.6
-
43
-
-
84894411984
-
The hypocretin/orexin receptor-1 as a novel target to modulate cannabinoid reward
-
Flores, A., Maldonado, R., and Berrendero, F. (2014). The hypocretin/orexin receptor-1 as a novel target to modulate cannabinoid reward. Biol. Psychiatry 75, 499-507. doi: 10.1016/j.biopsych.2013.06.012
-
(2014)
Biol. Psychiatry
, vol.75
, pp. 499-507
-
-
Flores, A.1
Maldonado, R.2
Berrendero, F.3
-
44
-
-
84862664017
-
Utility of genetically modified mice for understanding the neurobiology of substance use disorders
-
Fowler, C. D., and Kenny, P. J. (2012). Utility of genetically modified mice for understanding the neurobiology of substance use disorders. Hum. Genet. 131, 941-957. doi: 10.1007/s00439-011-1129-z
-
(2012)
Hum. Genet.
, vol.131
, pp. 941-957
-
-
Fowler, C.D.1
Kenny, P.J.2
-
45
-
-
84881097633
-
Molecular mechanisms of cannabinoid addiction
-
Fratta, W., and Fattore, L. (2013). Molecular mechanisms of cannabinoid addiction. Curr. Opin. Neurobiol. 23, 487-492. doi: 10.1016/j.conb.2013.02.002
-
(2013)
Curr. Opin. Neurobiol.
, vol.23
, pp. 487-492
-
-
Fratta, W.1
Fattore, L.2
-
46
-
-
80054109238
-
Key questions of endocannabinoid signalling in the CNS: which, where and when?
-
Frazier, C. J. (2011). Key questions of endocannabinoid signalling in the CNS: which, where and when? J. Physiol. 589, 4807-4808. doi: 10.1113/jphysiol.2011.219493
-
(2011)
J. Physiol.
, vol.589
, pp. 4807-4808
-
-
Frazier, C.J.1
-
47
-
-
84906834240
-
Revolution in GPCR signalling: opioid receptor heteromers as novel therapeutic targets: IUPHAR review 10
-
Fujita, W., Gomes, I., and Devi, L. A. (2014). Revolution in GPCR signalling: opioid receptor heteromers as novel therapeutic targets: IUPHAR review 10. Br. J. Pharmacol. 171, 4155-4176. doi: 10.1111/bph.12798
-
(2014)
Br. J. Pharmacol.
, vol.171
, pp. 4155-4176
-
-
Fujita, W.1
Gomes, I.2
Devi, L.A.3
-
48
-
-
84877820530
-
Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation
-
Gaffal, E., Cron, M., Glodde, N., Bald, T., Kuner, R., Zimmer, A.,et al. (2013). Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation. J. Immunol. 190, 4929-4936. doi: 10.4049/jimmunol.1201777
-
(2013)
J. Immunol.
, vol.190
, pp. 4929-4936
-
-
Gaffal, E.1
Cron, M.2
Glodde, N.3
Bald, T.4
Kuner, R.5
Zimmer, A.6
-
49
-
-
76649137560
-
Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice
-
Gao, Y., Vasilyev, D. V., Goncalves, M. B., Howell, F. V., Hobbs, C., Reisenberg, M.,et al. (2010). Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice. J. Neurosci. 30, 2017-2024. doi: 10.1523/JNEUROSCI.5693-09.2010
-
(2010)
J. Neurosci.
, vol.30
, pp. 2017-2024
-
-
Gao, Y.1
Vasilyev, D.V.2
Goncalves, M.B.3
Howell, F.V.4
Hobbs, C.5
Reisenberg, M.6
-
50
-
-
20444398090
-
Endocannabinoid signaling system and brain reward: emphasis on dopamine
-
Gardner, E. L. (2005). Endocannabinoid signaling system and brain reward: emphasis on dopamine. Pharmacol. Biochem. Behav. 81, 263-284. doi: 10.1016/j.pbb.2005.01.032
-
(2005)
Pharmacol. Biochem. Behav.
, vol.81
, pp. 263-284
-
-
Gardner, E.L.1
-
51
-
-
84884187234
-
Opiate-induced analgesia: contributions from mu, delta and kappa opioid receptors mouse mutants
-
Gaveriaux-Ruff, C. (2013). Opiate-induced analgesia: contributions from mu, delta and kappa opioid receptors mouse mutants. Curr. Pharm. Des 19, 7373-7381. doi: 10.2174/138161281942140105163727
-
(2013)
Curr. Pharm. Des
, vol.19
, pp. 7373-7381
-
-
Gaveriaux-Ruff, C.1
-
52
-
-
79956153093
-
Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia
-
Gaveriaux-Ruff, C., Nozaki, C., Nadal, X., Hever, X. C., Weibel, R., Matifas, A.,et al. (2011). Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia. Pain 152, 1238-1248. doi: 10.1016/j.pain.2010.12.031
-
(2011)
Pain
, vol.152
, pp. 1238-1248
-
-
Gaveriaux-Ruff, C.1
Nozaki, C.2
Nadal, X.3
Hever, X.C.4
Weibel, R.5
Matifas, A.6
-
53
-
-
44549088448
-
Gene expression of opioid and dopamine systems in mouse striatum: effects of CB1 receptors, age and sex
-
Gerald, T. M., Howlett, A. C., Ward, G. R., Ho, C., and Franklin, S. O. (2008). Gene expression of opioid and dopamine systems in mouse striatum: effects of CB1 receptors, age and sex. Psychopharmacology (Berl.) 198, 497-508. doi: 10.1007/s00213-008-1141-1148
-
(2008)
Psychopharmacology (Berl.)
, vol.198
, pp. 497-508
-
-
Gerald, T.M.1
Howlett, A.C.2
Ward, G.R.3
Ho, C.4
Franklin, S.O.5
-
54
-
-
33745403776
-
CB1 knockout mice display significant changes in striatal opioid peptide and D4 dopamine receptor gene expression
-
Gerald, T. M., Ward, G. R., Howlett, A. C., and Franklin, S. O. (2006). CB1 knockout mice display significant changes in striatal opioid peptide and D4 dopamine receptor gene expression. Brain Res. 1093, 20-24. doi: 10.1016/j.brainres.2006.03.088
-
(2006)
Brain Res.
, vol.1093
, pp. 20-24
-
-
Gerald, T.M.1
Ward, G.R.2
Howlett, A.C.3
Franklin, S.O.4
-
55
-
-
0036470141
-
Motivational effects of cannabinoids are mediated by mu-opioid and kappa-opioid receptors
-
Ghozland, S., Matthes, H. W., Simonin, F., Filliol, D., Kieffer, B. L., and Maldonado, R. (2002). Motivational effects of cannabinoids are mediated by mu-opioid and kappa-opioid receptors. J. Neurosci. 22, 1146-1154.
-
(2002)
J. Neurosci.
, vol.22
, pp. 1146-1154
-
-
Ghozland, S.1
Matthes, H.W.2
Simonin, F.3
Filliol, D.4
Kieffer, B.L.5
Maldonado, R.6
-
56
-
-
32844465920
-
Cannabinoid CB2 receptors: immunohistochemical localization in rat brain
-
Gong, J. P., Onaivi, E. S., Ishiguro, H., Liu, Q. R., Tagliaferro, P. A., Brusco, A.,et al. (2006). Cannabinoid CB2 receptors: immunohistochemical localization in rat brain. Brain Res. 1071, 10-23. doi: 10.1016/j.brainres.2005.11.035
-
(2006)
Brain Res.
, vol.1071
, pp. 10-23
-
-
Gong, J.P.1
Onaivi, E.S.2
Ishiguro, H.3
Liu, Q.R.4
Tagliaferro, P.A.5
Brusco, A.6
-
57
-
-
0037178644
-
Quantitative autoradiographic mapping of opioid receptors in the brain of delta-opioid receptor gene knockout mice
-
Goody, R. J., Oakley, S. M., Filliol, D., Kieffer, B. L., and Kitchen, I. (2002). Quantitative autoradiographic mapping of opioid receptors in the brain of delta-opioid receptor gene knockout mice. Brain Res. 945, 9-19. doi: 10.1016/S0006-8993(02)02452-6
-
(2002)
Brain Res.
, vol.945
, pp. 9-19
-
-
Goody, R.J.1
Oakley, S.M.2
Filliol, D.3
Kieffer, B.L.4
Kitchen, I.5
-
58
-
-
80053496448
-
Cost of disorders of the brain in Europe 2010
-
Gustavsson, A., Svensson, M., Jacobi, F., Allgulander, C., Alonso, J., Beghi, E.,et al. (2011). Cost of disorders of the brain in Europe 2010. Eur. Neuropsychopharmacol. 21, 718-779. doi: 10.1016/j.euroneuro.2011.08.008
-
(2011)
Eur. Neuropsychopharmacol.
, vol.21
, pp. 718-779
-
-
Gustavsson, A.1
Svensson, M.2
Jacobi, F.3
Allgulander, C.4
Alonso, J.5
Beghi, E.6
-
59
-
-
84936142874
-
Effects of genetic deletion of endogenous opioid system components on the reinstatement of cocaine-seeking behavior in mice
-
Gutierrez-Cuesta, J., Burokas, A., Mancino, S., Kummer, S., Martin-Garcia, E., and Maldonado, R. (2014). Effects of genetic deletion of endogenous opioid system components on the reinstatement of cocaine-seeking behavior in mice. Neuropsychopharmacology. doi: 10.1038/npp.2014.149
-
(2014)
Neuropsychopharmacology.
-
-
Gutierrez-Cuesta, J.1
Burokas, A.2
Mancino, S.3
Kummer, S.4
Martin-Garcia, E.5
Maldonado, R.6
-
60
-
-
84863244650
-
Acute cannabinoids impair working memory through astroglial CB1 receptor modulation of hippocampal LTD
-
Han, J., Kesner, P., Metna-Laurent, M., Duan, T., Xu, L., Georges, F.,et al. (2012). Acute cannabinoids impair working memory through astroglial CB1 receptor modulation of hippocampal LTD. Cell 148, 1039-1050. doi: 10.1016/j.cell.2012.01.037
-
(2012)
Cell
, vol.148
, pp. 1039-1050
-
-
Han, J.1
Kesner, P.2
Metna-Laurent, M.3
Duan, T.4
Xu, L.5
Georges, F.6
-
61
-
-
0034644827
-
Improgan, a cimetidine analog, induces morphine-like antinociception in opioid receptor-knockout mice
-
Hough, L. B., Nalwalk, J. W., Chen, Y., Schuller, A., Zhu, Y., Zhang, J.,et al. (2000). Improgan, a cimetidine analog, induces morphine-like antinociception in opioid receptor-knockout mice. Brain Res. 880, 102-108. doi: 10.1016/S0006-8993(00)02776-1
-
(2000)
Brain Res.
, vol.880
, pp. 102-108
-
-
Hough, L.B.1
Nalwalk, J.W.2
Chen, Y.3
Schuller, A.4
Zhu, Y.5
Zhang, J.6
-
62
-
-
84885406191
-
The cannabinoid CB2 receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice
-
Ignatowska-Jankowska, B. M., Muldoon, P. P., Lichtman, A. H., and Damaj, M. I. (2013). The cannabinoid CB2 receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice. Psychopharmacology (Berl) 229, 591-601. doi: 10.1007/s00213-013-3117-6
-
(2013)
Psychopharmacology (Berl)
, vol.229
, pp. 591-601
-
-
Ignatowska-Jankowska, B.M.1
Muldoon, P.P.2
Lichtman, A.H.3
Damaj, M.I.4
-
63
-
-
0038845604
-
Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors
-
Jarai, Z., Wagner, J. A., Varga, K., Lake, K. D., Compton, D. R., Martin, B. R.,et al. (1999). Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proc. Natl. Acad. Sci. U.S.A. 96, 14136-14141. doi: 10.1073/pnas.96.24.14136
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 14136-14141
-
-
Jarai, Z.1
Wagner, J.A.2
Varga, K.3
Lake, K.D.4
Compton, D.R.5
Martin, B.R.6
-
64
-
-
38649114788
-
Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver
-
Jeong, W. I., Osei-Hyiaman, D., Park, O., Liu, J., Batkai, S., Mukhopadhyay, P.,et al. (2008). Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver. Cell Metab. 7, 227-235. doi: 10.1016/j.cmet.2007.12.007
-
(2008)
Cell Metab.
, vol.7
, pp. 227-235
-
-
Jeong, W.I.1
Osei-Hyiaman, D.2
Park, O.3
Liu, J.4
Batkai, S.5
Mukhopadhyay, P.6
-
65
-
-
0029417155
-
Recent advances in molecular recognition and signal transduction of active peptides: receptors for opioid peptides
-
Kieffer, B. L. (1995). Recent advances in molecular recognition and signal transduction of active peptides: receptors for opioid peptides. Cell Mol. Neurobiol. 15, 615-635. doi: 10.1007/BF02071128
-
(1995)
Cell Mol. Neurobiol.
, vol.15
, pp. 615-635
-
-
Kieffer, B.L.1
-
66
-
-
0027052952
-
The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization
-
Kieffer, B. L., Befort, K., Gaveriaux-Ruff, C., and Hirth, C. G. (1992). The delta-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization. Proc. Natl. Acad. Sci. U.S.A. 89, 12048-12052. doi: 10.1073/pnas.89.24.12048
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 12048-12052
-
-
Kieffer, B.L.1
Befort, K.2
Gaveriaux-Ruff, C.3
Hirth, C.G.4
-
67
-
-
0036095186
-
Exploring the opioid system by gene knockout
-
Kieffer, B. L., and Gaveriaux-Ruff, C. (2002). Exploring the opioid system by gene knockout. Prog. Neurobiol. 66, 285-306. doi: 10.1016/S0301-0082(02)00008-4
-
(2002)
Prog. Neurobiol.
, vol.66
, pp. 285-306
-
-
Kieffer, B.L.1
Gaveriaux-Ruff, C.2
-
68
-
-
0031555309
-
Quantitative autoradiographic mapping of mu-, delta-, and kappa-opioid receptors in knockout mice lacking the mu-opioid receptor gene
-
Kitchen, I., Slowe, S. J., Matthes, H. W., and Kieffer, B. (1997). Quantitative autoradiographic mapping of mu-, delta-, and kappa-opioid receptors in knockout mice lacking the mu-opioid receptor gene. Brain Res. 778, 73-88. doi: 10.1016/S0006-8993(97)00988-8
-
(1997)
Brain Res.
, vol.778
, pp. 73-88
-
-
Kitchen, I.1
Slowe, S.J.2
Matthes, H.W.3
Kieffer, B.4
-
69
-
-
0029957953
-
Pain responses, anxiety and aggression in mice deficient in pre-proenkephalin
-
Konig, M., Zimmer, A. M., Steiner, H., Holmes, P. V., Crawley, J. N., Brownstein, M. J.,et al. (1996). Pain responses, anxiety and aggression in mice deficient in pre-proenkephalin. Nature 383, 535-538. doi: 10.1038/383535a0
-
(1996)
Nature
, vol.383
, pp. 535-538
-
-
Konig, M.1
Zimmer, A.M.2
Steiner, H.3
Holmes, P.V.4
Crawley, J.N.5
Brownstein, M.J.6
-
70
-
-
58049147045
-
Neurobiological substrates for the dark side of compulsivity in addiction
-
Koob, G. F. (2009). Neurobiological substrates for the dark side of compulsivity in addiction. Neuropharmacology 56(Suppl. 1), 18-31. doi: 10.1016/j.neuropharm.2008.07.043
-
(2009)
Neuropharmacology
, vol.56
, pp. 18-31
-
-
Koob, G.F.1
-
71
-
-
72049098472
-
Neurocircuitry of addiction
-
Koob, G. F., and Volkow, N. D. (2010). Neurocircuitry of addiction. Neuropsychopharmacology 35, 217-238. doi: 10.1038/npp.2009.110
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 217-238
-
-
Koob, G.F.1
Volkow, N.D.2
-
72
-
-
84867164588
-
Opiate addiction and cocaine addiction: underlying molecular neurobiology and genetics
-
Kreek, M. J., Levran, O., Reed, B., Schlussman, S. D., Zhou, Y., and Butelman, E. R. (2012). Opiate addiction and cocaine addiction: underlying molecular neurobiology and genetics. J. Clin. Invest. 122, 3387-3393. doi: 10.1172/JCI60390
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 3387-3393
-
-
Kreek, M.J.1
Levran, O.2
Reed, B.3
Schlussman, S.D.4
Zhou, Y.5
Butelman, E.R.6
-
73
-
-
70349682196
-
Reward processing by the opioid system in the brain
-
Le Merrer, J., Becker, J. A., Befort, K., and Kieffer, B. L. (2009). Reward processing by the opioid system in the brain. Physiol. Rev. 89, 1379-1412. doi: 10.1152/physrev.00005.2009
-
(2009)
Physiol. Rev.
, vol.89
, pp. 1379-1412
-
-
Le Merrer, J.1
Becker, J.A.2
Befort, K.3
Kieffer, B.L.4
-
74
-
-
84880174862
-
Bivalent ligands that target mu opioid (MOP) and cannabinoid1 (CB1) receptors are potent analgesics devoid of tolerance
-
Le Naour, M., Akgun, E., Yekkirala, A., Lunzer, M. M., Powers, M. D., Kalyuzhny, A. E.,et al. (2013). Bivalent ligands that target mu opioid (MOP) and cannabinoid1 (CB1) receptors are potent analgesics devoid of tolerance. J. Med. Chem. 56, 5505-5513. doi: 10.1021/jm4005219
-
(2013)
J. Med. Chem.
, vol.56
, pp. 5505-5513
-
-
Le Naour, M.1
Akgun, E.2
Yekkirala, A.3
Lunzer, M.M.4
Powers, M.D.5
Kalyuzhny, A.E.6
-
75
-
-
0033555839
-
Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice
-
Ledent, C., Valverde, O., Cossu, G., Petitet, F., Aubert, J. F., Beslot, F.,et al. (1999). Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science 283, 401-404. doi: 10.1126/science.283.5400.401
-
(1999)
Science
, vol.283
, pp. 401-404
-
-
Ledent, C.1
Valverde, O.2
Cossu, G.3
Petitet, F.4
Aubert, J.F.5
Beslot, F.6
-
76
-
-
0030816449
-
Addiction is a brain disease, and it matters
-
Leshner, A. I. (1997). Addiction is a brain disease, and it matters. Science 278, 45-47. doi: 10.1126/science.278.5335.45
-
(1997)
Science
, vol.278
, pp. 45-47
-
-
Leshner, A.I.1
-
77
-
-
33645935391
-
Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids
-
Leung, D., Saghatelian, A., Simon, G. M., and Cravatt, B. F. (2006). Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids. Biochemistry 45, 4720-4726. doi: 10.1021/bi060163l
-
(2006)
Biochemistry
, vol.45
, pp. 4720-4726
-
-
Leung, D.1
Saghatelian, A.2
Simon, G.M.3
Cravatt, B.F.4
-
78
-
-
0034893982
-
Opioid and cannabinoid modulation of precipitated withdrawal in delta(9)-tetrahydrocannabinol and morphine-dependent mice
-
Lichtman, A. H., Sheikh, S. M., Loh, H. H., and Martin, B. R. (2001). Opioid and cannabinoid modulation of precipitated withdrawal in delta(9)-tetrahydrocannabinol and morphine-dependent mice. J. Pharmacol. Exp. Ther. 298, 1007-1014.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.298
, pp. 1007-1014
-
-
Lichtman, A.H.1
Sheikh, S.M.2
Loh, H.H.3
Martin, B.R.4
-
79
-
-
37349020974
-
Multiple pathways involved in the biosynthesis of anandamide
-
Liu, J., Wang, L., Harvey-White, J., Huang, B. X., Kim, H. Y., Luquet, S.,et al. (2008). Multiple pathways involved in the biosynthesis of anandamide. Neuropharmacology 54, 1-7. doi: 10.1016/j.neuropharm.2007.05.020
-
(2008)
Neuropharmacology
, vol.54
, pp. 1-7
-
-
Liu, J.1
Wang, L.2
Harvey-White, J.3
Huang, B.X.4
Kim, H.Y.5
Luquet, S.6
-
80
-
-
34249730845
-
Endogenous dynorphin in epileptogenesis and epilepsy: anticonvulsant net effect via kappa opioid receptors
-
Loacker, S., Sayyah, M., Wittmann, W., Herzog, H., and Schwarzer, C. (2007). Endogenous dynorphin in epileptogenesis and epilepsy: anticonvulsant net effect via kappa opioid receptors. Brain 130, 1017-1028. doi: 10.1093/brain/awl384
-
(2007)
Brain
, vol.130
, pp. 1017-1028
-
-
Loacker, S.1
Sayyah, M.2
Wittmann, W.3
Herzog, H.4
Schwarzer, C.5
-
81
-
-
0032031040
-
mu Opioid receptor knockout in mice: effects on ligand-induced analgesia and morphine lethality
-
Loh, H. H., Liu, H. C., Cavalli, A., Yang, W., Chen, Y. F., and Wei, L. N. (1998). mu Opioid receptor knockout in mice: effects on ligand-induced analgesia and morphine lethality. Brain Res. Mol. Brain Res. 54, 321-326. doi: 10.1016/S0169-328X(97)00353-7
-
(1998)
Brain Res. Mol. Brain Res.
, vol.54
, pp. 321-326
-
-
Loh, H.H.1
Liu, H.C.2
Cavalli, A.3
Yang, W.4
Chen, Y.F.5
Wei, L.N.6
-
82
-
-
77950814617
-
Functional interactions between endogenous cannabinoid and opioid systems: focus on alcohol, genetics and drug-addicted behaviors
-
Lopez-Moreno, J. A., Lopez-Jimenez, A., Gorriti, M. A., and De Fonseca, F. R. (2010). Functional interactions between endogenous cannabinoid and opioid systems: focus on alcohol, genetics and drug-addicted behaviors. Curr. Drug Targets 11, 406-428. doi: 10.2174/138945010790980312
-
(2010)
Curr. Drug Targets
, vol.11
, pp. 406-428
-
-
Lopez-Moreno, J.A.1
Lopez-Jimenez, A.2
Gorriti, M.A.3
De Fonseca, F.R.4
-
83
-
-
84930888521
-
Distinct mu, delta, and kappa opioid receptor mechanisms underlie low sociability and depressive-like behaviors during heroin abstinence
-
Lutz, P. E., Ayranci, G., Chu-Sin-Chung, P., Matifas, A., Koebel, P., Filliol, D.,et al. (2014). Distinct mu, delta, and kappa opioid receptor mechanisms underlie low sociability and depressive-like behaviors during heroin abstinence. Neuropsychopharmacology 39, 2694-2705. doi: 10.1038/npp.2014.126
-
(2014)
Neuropsychopharmacology
, vol.39
, pp. 2694-2705
-
-
Lutz, P.E.1
Ayranci, G.2
Chu-Sin-Chung, P.3
Matifas, A.4
Koebel, P.5
Filliol, D.6
-
84
-
-
84881022559
-
The multiple facets of opioid receptor function: implications for addiction
-
Lutz, P. E., and Kieffer, B. L. (2013a). The multiple facets of opioid receptor function: implications for addiction. Curr. Opin. Neurobiol. 23, 473-479. doi: 10.1016/j.conb.2013.02.005
-
(2013)
Curr. Opin. Neurobiol.
, vol.23
, pp. 473-479
-
-
Lutz, P.E.1
Kieffer, B.L.2
-
85
-
-
84875273292
-
Opioid receptors: distinct roles in mood disorders
-
Lutz, P. E., and Kieffer, B. L. (2013b). Opioid receptors: distinct roles in mood disorders. Trends Neurosci. 36, 195-206. doi: 10.1016/j.tins.2012.11.002
-
(2013)
Trends Neurosci.
, vol.36
, pp. 195-206
-
-
Lutz, P.E.1
Kieffer, B.L.2
-
86
-
-
0034924282
-
Anandamide degradation and N-acylethanolamines level in wild-type and CB1 cannabinoid receptor knockout mice of different ages
-
Maccarrone, M., Attina, M., Bari, M., Cartoni, A., Ledent, C., and Finazzi-Agro, A. (2001). Anandamide degradation and N-acylethanolamines level in wild-type and CB1 cannabinoid receptor knockout mice of different ages. J. Neurochem. 78, 339-348. doi: 10.1046/j.1471-4159.2001.00413.x
-
(2001)
J. Neurochem.
, vol.78
, pp. 339-348
-
-
Maccarrone, M.1
Attina, M.2
Bari, M.3
Cartoni, A.4
Ledent, C.5
Finazzi-Agro, A.6
-
87
-
-
18744396333
-
Age-related changes of anandamide metabolism in CB1 cannabinoid receptor knockout mice: correlation with behaviour
-
Maccarrone, M., Valverde, O., Barbaccia, M. L., Castane, A., Maldonado, R., Ledent, C.,et al. (2002). Age-related changes of anandamide metabolism in CB1 cannabinoid receptor knockout mice: correlation with behaviour. Eur. J. Neurosci. 15, 1178-1186. doi: 10.1046/j.1460-9568.2002.01957.x
-
(2002)
Eur. J. Neurosci.
, vol.15
, pp. 1178-1186
-
-
Maccarrone, M.1
Valverde, O.2
Barbaccia, M.L.3
Castane, A.4
Maldonado, R.5
Ledent, C.6
-
88
-
-
33645774927
-
Distribution of cannabinoid receptors in the central and peripheral nervous system
-
Mackie, K. (2005). Distribution of cannabinoid receptors in the central and peripheral nervous system. Handb. Exp. Pharmacol. 299-325.
-
(2005)
Handb. Exp. Pharmacol
, pp. 299-325
-
-
Mackie, K.1
-
89
-
-
42349116262
-
Cannabinoid receptors: where they are and what they do
-
Mackie, K. (2008). Cannabinoid receptors: where they are and what they do. J. Neuroendocrinol. 20(Suppl. 1), 10-14. doi: 10.1111/j.1365-2826.2008.01671.x
-
(2008)
J. Neuroendocrinol.
, vol.20
, pp. 10-14
-
-
Mackie, K.1
-
90
-
-
0036669501
-
Study of cannabinoid dependence in animals
-
Maldonado, R. (2002). Study of cannabinoid dependence in animals. Pharmacol. Ther. 95, 153-164. doi: 10.1016/S0163-7258(02)00254-1
-
(2002)
Pharmacol. Ther.
, vol.95
, pp. 153-164
-
-
Maldonado, R.1
-
91
-
-
79953675661
-
Neurochemical basis of cannabis addiction
-
Maldonado, R., Berrendero, F., Ozaita, A., and Robledo, P. (2011). Neurochemical basis of cannabis addiction. Neuroscience 181, 1-17. doi: 10.1016/j.neuroscience.2011.02.035
-
(2011)
Neuroscience
, vol.181
, pp. 1-17
-
-
Maldonado, R.1
Berrendero, F.2
Ozaita, A.3
Robledo, P.4
-
92
-
-
0029764770
-
Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB
-
Maldonado, R., Blendy, J. A., Tzavara, E., Gass, P., Roques, B. P., Hanoune, J.,et al. (1996). Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB. Science 273, 657-659. doi: 10.1126/science.273.5275.657
-
(1996)
Science
, vol.273
, pp. 657-659
-
-
Maldonado, R.1
Blendy, J.A.2
Tzavara, E.3
Gass, P.4
Roques, B.P.5
Hanoune, J.6
-
93
-
-
84881027576
-
Endocannabinoid system and drug addiction: new insights from mutant mice approaches
-
Maldonado, R., Robledo, P., and Berrendero, F. (2013). Endocannabinoid system and drug addiction: new insights from mutant mice approaches. Curr. Opin. Neurobiol. 23, 480-486. doi: 10.1016/j.conb.2013.02.004
-
(2013)
Curr. Opin. Neurobiol.
, vol.23
, pp. 480-486
-
-
Maldonado, R.1
Robledo, P.2
Berrendero, F.3
-
94
-
-
33645982868
-
Involvement of the endocannabinoid system in drug addiction
-
Maldonado, R., Valverde, O., and Berrendero, F. (2006). Involvement of the endocannabinoid system in drug addiction. Trends Neurosci. 29, 225-232. doi: 10.1016/j.tins.2006.01.008
-
(2006)
Trends Neurosci.
, vol.29
, pp. 225-232
-
-
Maldonado, R.1
Valverde, O.2
Berrendero, F.3
-
95
-
-
0028887626
-
Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications
-
Mansour, A., Fox, C. A., Akil, H., and Watson, S. J. (1995). Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications. Trends Neurosci. 18, 22-29. doi: 10.1016/0166-2236(95)93946-U
-
(1995)
Trends Neurosci.
, vol.18
, pp. 22-29
-
-
Mansour, A.1
Fox, C.A.2
Akil, H.3
Watson, S.J.4
-
96
-
-
0343718836
-
Pharmacological and biochemical interactions between opioids and cannabinoids
-
Manzanares, J., Corchero, J., Romero, J., Fernandez-Ruiz, J. J., Ramos, J. A., and Fuentes, J. A. (1999). Pharmacological and biochemical interactions between opioids and cannabinoids. Trends Pharmacol. Sci. 20, 287-294. doi: 10.1016/S0165-6147(99)01339-5
-
(1999)
Trends Pharmacol. Sci.
, vol.20
, pp. 287-294
-
-
Manzanares, J.1
Corchero, J.2
Romero, J.3
Fernandez-Ruiz, J.J.4
Ramos, J.A.5
Fuentes, J.A.6
-
97
-
-
34147165471
-
Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells
-
Maresz, K., Pryce, G., Ponomarev, E. D., Marsicano, G., Croxford, J. L., Shriver, L. P.,et al. (2007). Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells. Nat. Med. 13, 492-497. doi: 10.1038/nm1561
-
(2007)
Nat. Med.
, vol.13
, pp. 492-497
-
-
Maresz, K.1
Pryce, G.2
Ponomarev, E.D.3
Marsicano, G.4
Croxford, J.L.5
Shriver, L.P.6
-
98
-
-
0141865717
-
CB1 cannabinoid receptors and on-demand defense against excitotoxicity
-
Marsicano, G., Goodenough, S., Monory, K., Hermann, H., Eder, M., Cannich, A.,et al. (2003). CB1 cannabinoid receptors and on-demand defense against excitotoxicity. Science 302, 84-88. doi: 10.1126/science.1088208
-
(2003)
Science
, vol.302
, pp. 84-88
-
-
Marsicano, G.1
Goodenough, S.2
Monory, K.3
Hermann, H.4
Eder, M.5
Cannich, A.6
-
99
-
-
0036682222
-
The endogenous cannabinoid system controls extinction of aversive memories
-
Marsicano, G., Wotjak, C. T., Azad, S. C., Bisogno, T., Rammes, G., Cascio, M. G.,et al. (2002). The endogenous cannabinoid system controls extinction of aversive memories. Nature 418, 530-534. doi: 10.1038/nature00839
-
(2002)
Nature
, vol.418
, pp. 530-534
-
-
Marsicano, G.1
Wotjak, C.T.2
Azad, S.C.3
Bisogno, T.4
Rammes, G.5
Cascio, M.G.6
-
100
-
-
0032495834
-
Self-administration of the cannabinoid receptor agonist WIN 55,212-2 in drug-naive mice
-
Martellotta, M. C., Cossu, G., Fattore, L., Gessa, G. L., and Fratta, W. (1998). Self-administration of the cannabinoid receptor agonist WIN 55,212-2 in drug-naive mice. Neuroscience 85, 327-330. doi: 10.1016/S0306-4522(98)00052-9
-
(1998)
Neuroscience
, vol.85
, pp. 327-330
-
-
Martellotta, M.C.1
Cossu, G.2
Fattore, L.3
Gessa, G.L.4
Fratta, W.5
-
101
-
-
0033777338
-
Cocaine, but not morphine, induces conditioned place preference and sensitization to locomotor responses in CB1 knockout mice
-
Martin, M., Ledent, C., Parmentier, M., Maldonado, R., and Valverde, O. (2000). Cocaine, but not morphine, induces conditioned place preference and sensitization to locomotor responses in CB1 knockout mice. Eur. J. Neurosci. 12, 4038-4046. doi: 10.1046/j.1460-9568.2000.00287.x
-
(2000)
Eur. J. Neurosci.
, vol.12
, pp. 4038-4046
-
-
Martin, M.1
Ledent, C.2
Parmentier, M.3
Maldonado, R.4
Valverde, O.5
-
102
-
-
0032786408
-
Lack of morphine-induced dopamine release in the nucleus accumbens of cannabinoid CB(1) receptor knockout mice
-
Mascia, M. S., Obinu, M. C., Ledent, C., Parmentier, M., Bohme, G. A., Imperato, A.,et al. (1999). Lack of morphine-induced dopamine release in the nucleus accumbens of cannabinoid CB(1) receptor knockout mice. Eur. J. Pharmacol 383, R1-R2. doi: 10.1016/S0014-2999(99)00656-1
-
(1999)
Eur. J. Pharmacol
, vol.383
, pp. R1-R2
-
-
Mascia, M.S.1
Obinu, M.C.2
Ledent, C.3
Parmentier, M.4
Bohme, G.A.5
Imperato, A.6
-
103
-
-
84920169231
-
In vivo opioid receptor heteromerization: where do we stand?
-
Massotte, D. (2014). In vivo opioid receptor heteromerization: where do we stand? Br. J. Pharmacol. 172, 420-434. doi: 10.1111/bph.12702
-
(2014)
Br. J. Pharmacol.
, vol.172
, pp. 420-434
-
-
Massotte, D.1
-
104
-
-
0025325535
-
Structure of a cannabinoid receptor and functional expression of the cloned cDNA
-
Matsuda, L. A., Lolait, S. J., Brownstein, M. J., Young, A. C., and Bonner, T. I. (1990). Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 346, 561-564. doi: 10.1038/346561a0
-
(1990)
Nature
, vol.346
, pp. 561-564
-
-
Matsuda, L.A.1
Lolait, S.J.2
Brownstein, M.J.3
Young, A.C.4
Bonner, T.I.5
-
105
-
-
0029852678
-
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene
-
Matthes, H. W., Maldonado, R., Simonin, F., Valverde, O., Slowe, S., Kitchen, I.,et al. (1996). Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature 383, 819-823. doi: 10.1038/383819a0
-
(1996)
Nature
, vol.383
, pp. 819-823
-
-
Matthes, H.W.1
Maldonado, R.2
Simonin, F.3
Valverde, O.4
Slowe, S.5
Kitchen, I.6
-
106
-
-
33747333091
-
Involvement of kappa/dynorphin system in WIN 55,212-2 self-administration in mice
-
Mendizabal, V., Zimmer, A., and Maldonado, R. (2006). Involvement of kappa/dynorphin system in WIN 55,212-2 self-administration in mice. Neuropsychopharmacology 31, 1957-1966. doi: 10.1038/sj.npp.1300957
-
(2006)
Neuropsychopharmacology
, vol.31
, pp. 1957-1966
-
-
Mendizabal, V.1
Zimmer, A.2
Maldonado, R.3
-
107
-
-
0028952242
-
The human mu opioid receptor: modulation of functional desensitization by calcium/calmodulin-dependent protein kinase and protein kinase C
-
Mestek, A., Hurley, J. H., Bye, L. S., Campbell, A. D., Chen, Y., Tian, M.,et al. (1995). The human mu opioid receptor: modulation of functional desensitization by calcium/calmodulin-dependent protein kinase and protein kinase C. J. Neurosci. 15, 2396-2406.
-
(1995)
J. Neurosci.
, vol.15
, pp. 2396-2406
-
-
Mestek, A.1
Hurley, J.H.2
Bye, L.S.3
Campbell, A.D.4
Chen, Y.5
Tian, M.6
-
108
-
-
77957374840
-
Lack of a rewarding effect and a locomotor-enhancing effect of the selective mu-opioid receptor agonist amidino-TAPA
-
Mizoguchi, H., Watanabe, C., Osada, S., Yoshioka, M., Aoki, Y., Natsui, S.,et al. (2010). Lack of a rewarding effect and a locomotor-enhancing effect of the selective mu-opioid receptor agonist amidino-TAPA. Psychopharmacology (Berl) 212, 215-225. doi: 10.1007/s00213-010-1946-0
-
(2010)
Psychopharmacology (Berl)
, vol.212
, pp. 215-225
-
-
Mizoguchi, H.1
Watanabe, C.2
Osada, S.3
Yoshioka, M.4
Aoki, Y.5
Natsui, S.6
-
109
-
-
35649000942
-
Genetic dissection of behavioural and autonomic effects of Delta(9)-tetrahydrocannabinol in mice
-
Monory, K., Blaudzun, H., Massa, F., Kaiser, N., Lemberger, T., Schutz, G.,et al. (2007). Genetic dissection of behavioural and autonomic effects of Delta(9)-tetrahydrocannabinol in mice. PLoS Biol. 5:e269. doi: 10.1371/journal.pbio.0050269
-
(2007)
PLoS Biol
, vol.5
-
-
Monory, K.1
Blaudzun, H.2
Massa, F.3
Kaiser, N.4
Lemberger, T.5
Schutz, G.6
-
110
-
-
33746913292
-
The endocannabinoid system controls key epileptogenic circuits in the hippocampus
-
Monory, K., Massa, F., Egertova, M., Eder, M., Blaudzun, H., Westenbroek, R.,et al. (2006). The endocannabinoid system controls key epileptogenic circuits in the hippocampus. Neuron 51, 455-466. doi: 10.1016/j.neuron.2006.07.006
-
(2006)
Neuron
, vol.51
, pp. 455-466
-
-
Monory, K.1
Massa, F.2
Egertova, M.3
Eder, M.4
Blaudzun, H.5
Westenbroek, R.6
-
111
-
-
0027515373
-
Molecular characterization of a peripheral receptor for cannabinoids
-
Munro, S., Thomas, K. L., and Abu-Shaar, M. (1993). Molecular characterization of a peripheral receptor for cannabinoids. Nature 365, 61-65. doi: 10.1038/365061a0
-
(1993)
Nature
, vol.365
, pp. 61-65
-
-
Munro, S.1
Thomas, K.L.2
Abu-Shaar, M.3
-
112
-
-
84892541489
-
Involvement of the opioid and cannabinoid systems in pain control: new insights from knockout studies
-
Nadal, X., La Porta, C., Andreea Bura, S., and Maldonado, R. (2013). Involvement of the opioid and cannabinoid systems in pain control: new insights from knockout studies. Eur. J. Pharmacol. 716, 142-157. doi: 10.1016/j.ejphar.2013.01.077
-
(2013)
Eur. J. Pharmacol.
, vol.716
, pp. 142-157
-
-
Nadal, X.1
La Porta, C.2
Andreea Bura, S.3
Maldonado, R.4
-
113
-
-
84888347846
-
Role of CB2 cannabinoid receptors in the rewarding, reinforcing, and physical effects of nicotine
-
Navarrete, F., Rodriguez-Arias, M., Martin-Garcia, E., Navarro, D., Garcia-Gutierrez, M. S., Aguilar, M. A.,et al. (2013). Role of CB2 cannabinoid receptors in the rewarding, reinforcing, and physical effects of nicotine. Neuropsychopharmacology 38, 2515-2524. doi: 10.1038/npp.2013.157
-
(2013)
Neuropsychopharmacology
, vol.38
, pp. 2515-2524
-
-
Navarrete, F.1
Rodriguez-Arias, M.2
Martin-Garcia, E.3
Navarro, D.4
Garcia-Gutierrez, M.S.5
Aguilar, M.A.6
-
114
-
-
84887080253
-
Epigenetic mechanisms of drug addiction
-
Nestler, E. J. (2014). Epigenetic mechanisms of drug addiction. Neuropharmacology 76 Pt B, 259-268. doi: 10.1016/j.neuropharm.2013.04.004
-
(2014)
Neuropharmacology
, vol.76
, pp. 259-268
-
-
Nestler, E.J.1
-
115
-
-
39149103043
-
Implication of endogenous beta-endorphin in the inhibition of the morphine-induced rewarding effect by the direct activation of spinal protein kinase C in mice
-
Niikura, K., Narita, M., Okutsu, D., Tsurukawa, Y., Nanjo, K., Kurahashi, K.,et al. (2008). Implication of endogenous beta-endorphin in the inhibition of the morphine-induced rewarding effect by the direct activation of spinal protein kinase C in mice. Neurosci. Lett. 433, 54-58. doi: 10.1016/j.neulet.2007.12.042
-
(2008)
Neurosci. Lett.
, vol.433
, pp. 54-58
-
-
Niikura, K.1
Narita, M.2
Okutsu, D.3
Tsurukawa, Y.4
Nanjo, K.5
Kurahashi, K.6
-
116
-
-
84861903679
-
The opioid system and food intake: homeostatic and hedonic mechanisms
-
Nogueiras, R., Romero-Pico, A., Vazquez, M. J., Novelle, M. G., Lopez, M., and Dieguez, C. (2014). The opioid system and food intake: homeostatic and hedonic mechanisms. Obes. Facts 5, 196-207. doi: 10.1159/000338163
-
(2014)
Obes. Facts
, vol.5
, pp. 196-207
-
-
Nogueiras, R.1
Romero-Pico, A.2
Vazquez, M.J.3
Novelle, M.G.4
Lopez, M.5
Dieguez, C.6
-
117
-
-
12244297090
-
G-protein coupling of delta-opioid receptors in brains of mu-opioid receptor knockout mice
-
Oakley, S. M., Toth, G., Borsodi, A., Kieffer, B. L., and Kitchen, I. (2003). G-protein coupling of delta-opioid receptors in brains of mu-opioid receptor knockout mice. Eur. J. Pharmacol. 466, 91-98. doi: 10.1016/S0014-2999(03)01531-0
-
(2003)
Eur. J. Pharmacol.
, vol.466
, pp. 91-98
-
-
Oakley, S.M.1
Toth, G.2
Borsodi, A.3
Kieffer, B.L.4
Kitchen, I.5
-
118
-
-
84898872648
-
Endocannabinoid-mediated retrograde modulation of synaptic transmission
-
Ohno-Shosaku, T., and Kano, M. (2014). Endocannabinoid-mediated retrograde modulation of synaptic transmission. Curr. Opin. Neurobiol. 29C, 1-8. doi: 10.1016/j.conb.2014.03.017
-
(2014)
Curr. Opin. Neurobiol
, vol.29 C
, pp. 1-8
-
-
Ohno-Shosaku, T.1
Kano, M.2
-
119
-
-
33749544716
-
Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain
-
Onaivi, E. S., Ishiguro, H., Gong, J. P., Patel, S., Perchuk, A., Meozzi, P. A.,et al. (2006). Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain. Ann. N. Y. Acad. Sci. 1074, 514-536. doi: 10.1196/annals.1369.052
-
(2006)
Ann. N. Y. Acad. Sci.
, vol.1074
, pp. 514-536
-
-
Onaivi, E.S.1
Ishiguro, H.2
Gong, J.P.3
Patel, S.4
Perchuk, A.5
Meozzi, P.A.6
-
120
-
-
84919843841
-
Role of cannabinoid CB receptor in the reinforcing actions of ethanol
-
Ortega-Alvaro, A., Ternianov, A., Aracil-Fernandez, A., Navarrete, F., Garcia-Gutierrez, M. S., and Manzanares, J. (2013). Role of cannabinoid CB receptor in the reinforcing actions of ethanol. Addict. Biol. doi: 10.1111/adb.12076
-
(2013)
Addict. Biol.
-
-
Ortega-Alvaro, A.1
Ternianov, A.2
Aracil-Fernandez, A.3
Navarrete, F.4
Garcia-Gutierrez, M.S.5
Manzanares, J.6
-
121
-
-
63849228557
-
Involvement of exon 11-associated variants of the mu opioid receptor MOR-1 in heroin, but not morphine, actions
-
Pan, Y. X., Xu, J., Xu, M., Rossi, G. C., Matulonis, J. E., and Pasternak, G. W. (2009). Involvement of exon 11-associated variants of the mu opioid receptor MOR-1 in heroin, but not morphine, actions. Proc. Natl. Acad. Sci. U.S.A. 106, 4917-4922. doi: 10.1073/pnas.0811586106
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 4917-4922
-
-
Pan, Y.X.1
Xu, J.2
Xu, M.3
Rossi, G.C.4
Matulonis, J.E.5
Pasternak, G.W.6
-
122
-
-
84922470163
-
Cannabinoid regulation of brain reward processing with an emphasis on the role of CB1 receptors: a step back into the future
-
Panagis, G., Mackey, B., and Vlachou, S. (2014). Cannabinoid regulation of brain reward processing with an emphasis on the role of CB1 receptors: a step back into the future. Front. Psychiatry 5:92. doi: 10.3389/fpsyt.2014.00092
-
(2014)
Front. Psychiatry
, vol.5
, pp. 92
-
-
Panagis, G.1
Mackey, B.2
Vlachou, S.3
-
123
-
-
36349011790
-
Self-administration of drugs in animals and humans as a model and an investigative tool
-
Panlilio, L. V., and Goldberg, S. R. (2007). Self-administration of drugs in animals and humans as a model and an investigative tool. Addiction 102, 1863-1870. doi: 10.1111/j.1360-0443.2007.02011.x
-
(2007)
Addiction
, vol.102
, pp. 1863-1870
-
-
Panlilio, L.V.1
Goldberg, S.R.2
-
124
-
-
77952616365
-
Animal models of cannabinoid reward
-
Panlilio, L. V., Justinova, Z., and Goldberg, S. R. (2010). Animal models of cannabinoid reward. Br. J. Pharmacol. 160, 499-510. doi: 10.1111/j.1476-5381.2010.00775.x
-
(2010)
Br. J. Pharmacol.
, vol.160
, pp. 499-510
-
-
Panlilio, L.V.1
Justinova, Z.2
Goldberg, S.R.3
-
125
-
-
77950840678
-
Cellular mechanisms underlying the interaction between cannabinoid and opioid system
-
Parolaro, D., Rubino, T., Vigano, D., Massi, P., Guidali, C., and Realini, N. (2010). Cellular mechanisms underlying the interaction between cannabinoid and opioid system. Curr. Drug Targets 11, 393-405. doi: 10.2174/138945010790980367
-
(2010)
Curr. Drug Targets
, vol.11
, pp. 393-405
-
-
Parolaro, D.1
Rubino, T.2
Vigano, D.3
Massi, P.4
Guidali, C.5
Realini, N.6
-
126
-
-
84881107392
-
The role of impulsivity in relapse vulnerability
-
Pattij, T., and De Vries, T. J. (2013). The role of impulsivity in relapse vulnerability. Curr. Opin. Neurobiol. 23, 700-705. doi: 10.1016/j.conb.2013.01.023
-
(2013)
Curr. Opin. Neurobiol.
, vol.23
, pp. 700-705
-
-
Pattij, T.1
De Vries, T.J.2
-
127
-
-
77950653576
-
Receptors and channels targeted by synthetic cannabinoid receptor agonists and antagonists
-
Pertwee, R. G. (2010). Receptors and channels targeted by synthetic cannabinoid receptor agonists and antagonists. Curr. Med. Chem 17, 1360-1381. doi: 10.2174/092986710790980050
-
(2010)
Curr. Med. Chem
, vol.17
, pp. 1360-1381
-
-
Pertwee, R.G.1
-
128
-
-
84902515498
-
Augmented tonic pain-related behavior in knockout mice lacking monoacylglycerol lipase, a major degrading enzyme for the endocannabinoid 2-arachidonoylglycerol
-
Petrenko, A. B., Yamazaki, M., Sakimura, K., Kano, M., and Baba, H. (2014). Augmented tonic pain-related behavior in knockout mice lacking monoacylglycerol lipase, a major degrading enzyme for the endocannabinoid 2-arachidonoylglycerol. Behav. Brain Res. 271, 51-58. doi: 10.1016/j.bbr.2014.05.063
-
(2014)
Behav. Brain Res.
, vol.271
, pp. 51-58
-
-
Petrenko, A.B.1
Yamazaki, M.2
Sakimura, K.3
Kano, M.4
Baba, H.5
-
129
-
-
84887072489
-
More surprises lying ahead. The endocannabinoids keep us guessing
-
Piomelli, D. (2014). More surprises lying ahead. The endocannabinoids keep us guessing. Neuropharmacology 76 Pt B, 228-234. doi: 10.1016/j.neuropharm.2013.07.026
-
(2014)
Neuropharmacology
, vol.76
, pp. 228-234
-
-
Piomelli, D.1
-
130
-
-
30344449474
-
Expression of opioid receptors and c-fos in CB1 knockout mice exposed to neuropathic pain
-
Pol, O., Murtra, P., Caracuel, L., Valverde, O., Puig, M. M., and Maldonado, R. (2006). Expression of opioid receptors and c-fos in CB1 knockout mice exposed to neuropathic pain. Neuropharmacology 50, 123-132. doi: 10.1016/j.neuropharm.2005.11.002
-
(2006)
Neuropharmacology
, vol.50
, pp. 123-132
-
-
Pol, O.1
Murtra, P.2
Caracuel, L.3
Valverde, O.4
Puig, M.M.5
Maldonado, R.6
-
131
-
-
80051918265
-
The delta opioid receptor: an evolving target for the treatment of brain disorders
-
Pradhan, A. A., Befort, K., Nozaki, C., Gaveriaux-Ruff, C., and Kieffer, B. L. (2011). The delta opioid receptor: an evolving target for the treatment of brain disorders. Trends Pharmacol. Sci. 32, 581-590. doi: 10.1016/j.tips.2011.06.008
-
(2011)
Trends Pharmacol. Sci.
, vol.32
, pp. 581-590
-
-
Pradhan, A.A.1
Befort, K.2
Nozaki, C.3
Gaveriaux-Ruff, C.4
Kieffer, B.L.5
-
132
-
-
84894520596
-
Control of spasticity in a multiple sclerosis model using central nervous system-excluded CB1 cannabinoid receptor agonists
-
Pryce, G., Visintin, C., Ramagopalan, S. V., Al-Izki, S., De Faveri, L. E., Nuamah, R. A.,et al. (2014). Control of spasticity in a multiple sclerosis model using central nervous system-excluded CB1 cannabinoid receptor agonists. FASEB J. 28, 117-130. doi: 10.1096/fj.13-239442
-
(2014)
FASEB J.
, vol.28
, pp. 117-130
-
-
Pryce, G.1
Visintin, C.2
Ramagopalan, S.V.3
Al-Izki, S.4
De Faveri, L.E.5
Nuamah, R.A.6
-
133
-
-
0035852683
-
Female preproenkephalin-knockout mice display altered emotional responses
-
Ragnauth, A., Schuller, A., Morgan, M., Chan, J., Ogawa, S., Pintar, J.,et al. (2001). Female preproenkephalin-knockout mice display altered emotional responses. Proc. Natl. Acad. Sci. U.S.A. 98, 1958-1963. doi: 10.1073/pnas.041598498
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 1958-1963
-
-
Ragnauth, A.1
Schuller, A.2
Morgan, M.3
Chan, J.4
Ogawa, S.5
Pintar, J.6
-
134
-
-
84878576567
-
Dual inhibition of endocannabinoid catabolic enzymes produces enhanced antiwithdrawal effects in morphine-dependent mice
-
Ramesh, D., Gamage, T. F., Vanuytsel, T., Owens, R. A., Abdullah, R. A., Niphakis, M. J.,et al. (2013). Dual inhibition of endocannabinoid catabolic enzymes produces enhanced antiwithdrawal effects in morphine-dependent mice. Neuropsychopharmacology 38, 1039-1049. doi: 10.1038/npp.2012.269
-
(2013)
Neuropsychopharmacology
, vol.38
, pp. 1039-1049
-
-
Ramesh, D.1
Gamage, T.F.2
Vanuytsel, T.3
Owens, R.A.4
Abdullah, R.A.5
Niphakis, M.J.6
-
135
-
-
80053144160
-
Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice
-
Ramesh, D., Ross, G. R., Schlosburg, J. E., Owens, R. A., Abdullah, R. A., Kinsey, S. G.,et al. (2011). Blockade of endocannabinoid hydrolytic enzymes attenuates precipitated opioid withdrawal symptoms in mice. J. Pharmacol. Exp. Ther. 339, 173-185. doi: 10.1124/jpet.111.181370
-
(2011)
J. Pharmacol. Exp. Ther.
, vol.339
, pp. 173-185
-
-
Ramesh, D.1
Ross, G.R.2
Schlosburg, J.E.3
Owens, R.A.4
Abdullah, R.A.5
Kinsey, S.G.6
-
136
-
-
0037178689
-
Conditioned place preference to morphine in cannabinoid CB1 receptor knockout mice
-
Rice, O. V., Gordon, N., and Gifford, A. N. (2002). Conditioned place preference to morphine in cannabinoid CB1 receptor knockout mice. Brain Res. 945, 135-138. doi: 10.1016/S0006-8993(02)02890-1
-
(2002)
Brain Res.
, vol.945
, pp. 135-138
-
-
Rice, O.V.1
Gordon, N.2
Gifford, A.N.3
-
137
-
-
0037062421
-
Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens
-
Robbe, D., Kopf, M., Remaury, A., Bockaert, J., and Manzoni, O. J. (2002). Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens. Proc. Natl. Acad. Sci. U.S.A. 99, 8384-8388. doi: 10.1073/pnas.122149199
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 8384-8388
-
-
Robbe, D.1
Kopf, M.2
Remaury, A.3
Bockaert, J.4
Manzoni, O.J.5
-
138
-
-
51449093982
-
Review. The incentive sensitization theory of addiction: some current issues
-
Robinson, T. E., and Berridge, K. C. (2008). Review. The incentive sensitization theory of addiction: some current issues. Philos. Trans. R. Soc. Lond. B Biol. Sci. 363, 3137-3146. doi: 10.1098/rstb.2008.0093
-
(2008)
Philos. Trans. R. Soc. Lond. B Biol. Sci.
, vol.363
, pp. 3137-3146
-
-
Robinson, T.E.1
Berridge, K.C.2
-
139
-
-
43749109782
-
Advances in the field of cannabinoid-opioid cross-talk
-
Robledo, P., Berrendero, F., Ozaita, A., and Maldonado, R. (2008). Advances in the field of cannabinoid-opioid cross-talk. Addict. Biol. 13, 213-224. doi: 10.1111/j.1369-1600.2008.00107.x
-
(2008)
Addict. Biol.
, vol.13
, pp. 213-224
-
-
Robledo, P.1
Berrendero, F.2
Ozaita, A.3
Maldonado, R.4
-
140
-
-
84859324853
-
Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain
-
Roques, B. P., Fournie-Zaluski, M. C., and Wurm, M. (2012). Inhibiting the breakdown of endogenous opioids and cannabinoids to alleviate pain. Nat. Rev. Drug Discov. 11, 292-310. doi: 10.1038/nrd3673
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 292-310
-
-
Roques, B.P.1
Fournie-Zaluski, M.C.2
Wurm, M.3
-
141
-
-
0029880457
-
Absence of opioid stress-induced analgesia in mice lacking beta-endorphin by site-directed mutagenesis
-
Rubinstein, M., Mogil, J. S., Japon, M., Chan, E. C., Allen, R. G., and Low, M. J. (1996). Absence of opioid stress-induced analgesia in mice lacking beta-endorphin by site-directed mutagenesis. Proc. Natl. Acad. Sci. U.S.A. 93, 3995-4000. doi: 10.1073/pnas.93.9.3995
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 3995-4000
-
-
Rubinstein, M.1
Mogil, J.S.2
Japon, M.3
Chan, E.C.4
Allen, R.G.5
Low, M.J.6
-
142
-
-
84879135358
-
Cannabinoid CB1 receptor in dorsal telencephalic glutamatergic neurons: distinctive sufficiency for hippocampus-dependent and amygdala-dependent synaptic and behavioral functions
-
Ruehle, S., Remmers, F., Romo-Parra, H., Massa, F., Wickert, M., Wortge, S.,et al. (2013). Cannabinoid CB1 receptor in dorsal telencephalic glutamatergic neurons: distinctive sufficiency for hippocampus-dependent and amygdala-dependent synaptic and behavioral functions. J. Neurosci. 33, 10264-10277. doi: 10.1523/JNEUROSCI.4171-12.2013
-
(2013)
J. Neurosci.
, vol.33
, pp. 10264-10277
-
-
Ruehle, S.1
Remmers, F.2
Romo-Parra, H.3
Massa, F.4
Wickert, M.5
Wortge, S.6
-
143
-
-
8744258548
-
Reduced sensitivity to reward in CB1 knockout mice
-
Sanchis-Segura, C., Cline, B. H., Marsicano, G., Lutz, B., and Spanagel, R. (2004). Reduced sensitivity to reward in CB1 knockout mice. Psychopharmacology (Berl) 176, 223-232. doi: 10.1007/s00213-004-1877-1878
-
(2004)
Psychopharmacology (Berl)
, vol.176
, pp. 223-232
-
-
Sanchis-Segura, C.1
Cline, B.H.2
Marsicano, G.3
Lutz, B.4
Spanagel, R.5
-
144
-
-
33750686609
-
Behavioural assessment of drug reinforcement and addictive features in rodents: an overview
-
Sanchis-Segura, C., and Spanagel, R. (2006). Behavioural assessment of drug reinforcement and addictive features in rodents: an overview. Addict. Biol. 11, 2-38. doi: 10.1111/j.1369-1600.2006.00012.x
-
(2006)
Addict. Biol.
, vol.11
, pp. 2-38
-
-
Sanchis-Segura, C.1
Spanagel, R.2
-
145
-
-
84888014484
-
Individual variation in resisting temptation: implications for addiction
-
Saunders, B. T., and Robinson, T. E. (2013). Individual variation in resisting temptation: implications for addiction. Neurosci. Biobehav. Rev. 37, 1955-1975. doi: 10.1016/j.neubiorev.2013.02.008
-
(2013)
Neurosci. Biobehav. Rev.
, vol.37
, pp. 1955-1975
-
-
Saunders, B.T.1
Robinson, T.E.2
-
146
-
-
84881367408
-
Cannabinoid and opioid interactions: implications for opiate dependence and withdrawal
-
Scavone, J. L., Sterling, R. C., and Van Bockstaele, E. J. (2013). Cannabinoid and opioid interactions: implications for opiate dependence and withdrawal. Neuroscience 248, 637-654. doi: 10.1016/j.neuroscience.2013.04.034
-
(2013)
Neuroscience
, vol.248
, pp. 637-654
-
-
Scavone, J.L.1
Sterling, R.C.2
Van Bockstaele, E.J.3
-
147
-
-
77956181836
-
Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system
-
Schlosburg, J. E., Blankman, J. L., Long, J. Z., Nomura, D. K., Pan, B., Kinsey, S. G.,et al. (2010). Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system. Nat. Neurosci. 13, 1113-1119. doi: 10.1038/nn.2616
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 1113-1119
-
-
Schlosburg, J.E.1
Blankman, J.L.2
Long, J.Z.3
Nomura, D.K.4
Pan, B.5
Kinsey, S.G.6
-
148
-
-
0033366394
-
Retention of heroin and morphine-6 beta-glucuronide analgesia in a new line of mice lacking exon 1 of MOR-1
-
Schuller, A. G., King, M. A., Zhang, J., Bolan, E., Pan, Y. X., Morgan, D. J.,et al. (1999). Retention of heroin and morphine-6 beta-glucuronide analgesia in a new line of mice lacking exon 1 of MOR-1. Nat. Neurosci. 2, 151-156. doi: 10.1038/5706
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 151-156
-
-
Schuller, A.G.1
King, M.A.2
Zhang, J.3
Bolan, E.4
Pan, Y.X.5
Morgan, D.J.6
-
149
-
-
0035977718
-
Generation of dynorphin knockout mice
-
Sharifi, N., Diehl, N., Yaswen, L., Brennan, M. B., and Hochgeschwender, U. (2001). Generation of dynorphin knockout mice. Brain Res. Mol. Brain Res. 86, 70-75. doi: 10.1016/S0169-328X(00)00264-3
-
(2001)
Brain Res. Mol. Brain Res.
, vol.86
, pp. 70-75
-
-
Sharifi, N.1
Diehl, N.2
Yaswen, L.3
Brennan, M.B.4
Hochgeschwender, U.5
-
150
-
-
0028670235
-
The human delta-opioid receptor: genomic organization, cDNA cloning, functional expression, and distribution in human brain
-
Simonin, F., Befort, K., Gaveriaux-Ruff, C., Matthes, H., Nappey, V., Lannes, B.,et al. (1994). The human delta-opioid receptor: genomic organization, cDNA cloning, functional expression, and distribution in human brain. Mol. Pharmacol. 46, 1015-1021.
-
(1994)
Mol. Pharmacol.
, vol.46
, pp. 1015-1021
-
-
Simonin, F.1
Befort, K.2
Gaveriaux-Ruff, C.3
Matthes, H.4
Nappey, V.5
Lannes, B.6
-
151
-
-
0028983787
-
kappa-Opioid receptor in humans: cDNA and genomic cloning, chromosomal assignment, functional expression, pharmacology, and expression pattern in the central nervous system
-
Simonin, F., Gaveriaux-Ruff, C., Befort, K., Matthes, H., Lannes, B., Micheletti, G.,et al. (1995). kappa-Opioid receptor in humans: cDNA and genomic cloning, chromosomal assignment, functional expression, pharmacology, and expression pattern in the central nervous system. Proc. Natl. Acad. Sci. U.S.A. 92, 7006-7010. doi: 10.1073/pnas.92.15.7006
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 7006-7010
-
-
Simonin, F.1
Gaveriaux-Ruff, C.2
Befort, K.3
Matthes, H.4
Lannes, B.5
Micheletti, G.6
-
152
-
-
0035793687
-
Analysis of [3H]bremazocine binding in single and combinatorial opioid receptor knockout mice
-
Simonin, F., Slowe, S., Becker, J. A., Matthes, H. W., Filliol, D., Chluba, J.,et al. (2001). Analysis of [3H]bremazocine binding in single and combinatorial opioid receptor knockout mice. Eur. J. Pharmacol. 414, 189-195. doi: 10.1016/S0014-2999(01)00822-6
-
(2001)
Eur. J. Pharmacol.
, vol.414
, pp. 189-195
-
-
Simonin, F.1
Slowe, S.2
Becker, J.A.3
Matthes, H.W.4
Filliol, D.5
Chluba, J.6
-
153
-
-
0032481350
-
Disruption of the kappa-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective kappa-agonist U-50,488H and attenuates morphine withdrawal
-
Simonin, F., Valverde, O., Smadja, C., Slowe, S., Kitchen, I., Dierich, A.,et al. (1998). Disruption of the kappa-opioid receptor gene in mice enhances sensitivity to chemical visceral pain, impairs pharmacological actions of the selective kappa-agonist U-50,488H and attenuates morphine withdrawal. EMBO J. 17, 886-897. doi: 10.1093/emboj/17.4.886
-
(1998)
EMBO J.
, vol.17
, pp. 886-897
-
-
Simonin, F.1
Valverde, O.2
Smadja, C.3
Slowe, S.4
Kitchen, I.5
Dierich, A.6
-
154
-
-
17144418417
-
Endogenous enkephalins, not endorphins, modulate basal hedonic state in mice
-
Skoubis, P. D., Lam, H. A., Shoblock, J., Narayanan, S., and Maidment, N. T. (2005). Endogenous enkephalins, not endorphins, modulate basal hedonic state in mice. Eur. J. Neurosci. 21, 1379-1384. doi: 10.1111/j.1460-9568.2005.03956.x
-
(2005)
Eur. J. Neurosci.
, vol.21
, pp. 1379-1384
-
-
Skoubis, P.D.1
Lam, H.A.2
Shoblock, J.3
Narayanan, S.4
Maidment, N.T.5
-
155
-
-
0033550676
-
Quantitative autoradiography of mu-delta- and kappa1 opioid receptors in kappa-opioid receptor knockout mice
-
Slowe, S. J., Simonin, F., Kieffer, B., and Kitchen, I. (1999). Quantitative autoradiography of mu-delta- and kappa1 opioid receptors in kappa-opioid receptor knockout mice. Brain Res. 818, 335-345. doi: 10.1016/S0006-8993(98)01201-3
-
(1999)
Brain Res.
, vol.818
, pp. 335-345
-
-
Slowe, S.J.1
Simonin, F.2
Kieffer, B.3
Kitchen, I.4
-
156
-
-
43449127219
-
The endocannabinoid system in brain reward processes
-
Solinas, M., Goldberg, S. R., and Piomelli, D. (2008). The endocannabinoid system in brain reward processes. Br. J. Pharmacol. 154, 369-383. doi: 10.1038/bjp.2008.130
-
(2008)
Br. J. Pharmacol.
, vol.154
, pp. 369-383
-
-
Solinas, M.1
Goldberg, S.R.2
Piomelli, D.3
-
157
-
-
0035010041
-
Mu opiate receptor gene dose effects on different morphine actions: evidence for differential in vivo mu receptor reserve
-
Sora, I., Elmer, G., Funada, M., Pieper, J., Li, X. F., Hall, F. S.,et al. (2001). Mu opiate receptor gene dose effects on different morphine actions: evidence for differential in vivo mu receptor reserve. Neuropsychopharmacology 25, 41-54. doi: 10.1016/S0893-133X(00)00252-9
-
(2001)
Neuropsychopharmacology
, vol.25
, pp. 41-54
-
-
Sora, I.1
Elmer, G.2
Funada, M.3
Pieper, J.4
Li, X.F.5
Hall, F.S.6
-
158
-
-
84892575256
-
Opioids, sensory systems and chronic pain
-
Stein, C. (2013). Opioids, sensory systems and chronic pain. Eur. J. Pharmacol. 716, 179-187. doi: 10.1016/j.ejphar.2013.01.076
-
(2013)
Eur. J. Pharmacol.
, vol.716
, pp. 179-187
-
-
Stein, C.1
-
159
-
-
13044311373
-
Altered gene expression in striatal projection neurons in CB1 cannabinoid receptor knockout mice
-
Steiner, H., Bonner, T. I., Zimmer, A. M., Kitai, S. T., and Zimmer, A. (1999). Altered gene expression in striatal projection neurons in CB1 cannabinoid receptor knockout mice. Proc. Natl. Acad. Sci. U.S.A. 96, 5786-5790. doi: 10.1073/pnas.96.10.5786
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 5786-5790
-
-
Steiner, H.1
Bonner, T.I.2
Zimmer, A.M.3
Kitai, S.T.4
Zimmer, A.5
-
160
-
-
59949100369
-
Genetic loss of faah compromises male fertility in mice
-
Sun, X., Wang, H., Okabe, M., Mackie, K., Kingsley, P. J., Marnett, L. J.,et al. (2009). Genetic loss of faah compromises male fertility in mice. Biol. Reprod. 80, 235-242. doi: 10.1095/biolreprod.108.072736
-
(2009)
Biol. Reprod.
, vol.80
, pp. 235-242
-
-
Sun, X.1
Wang, H.2
Okabe, M.3
Mackie, K.4
Kingsley, P.J.5
Marnett, L.J.6
-
161
-
-
79251472090
-
Individual vulnerability to addiction
-
Swendsen, J., and Le Moal, M. (2011). Individual vulnerability to addiction. Ann. N. Y. Acad. Sci. 1216, 73-85. doi: 10.1111/j.1749-6632.2010.05894.x
-
(2011)
Ann. N. Y. Acad. Sci.
, vol.1216
, pp. 73-85
-
-
Swendsen, J.1
Le Moal, M.2
-
162
-
-
84900791580
-
Parental THC exposure leads to compulsive heroin-seeking and altered striatal synaptic plasticity in the subsequent generation
-
Szutorisz, H., Dinieri, J. A., Sweet, E., Egervari, G., Michaelides, M., Carter, J. M.,et al. (2014). Parental THC exposure leads to compulsive heroin-seeking and altered striatal synaptic plasticity in the subsequent generation. Neuropsychopharmacology 39, 1315-1323. doi: 10.1038/npp.2013.352
-
(2014)
Neuropsychopharmacology
, vol.39
, pp. 1315-1323
-
-
Szutorisz, H.1
Dinieri, J.A.2
Sweet, E.3
Egervari, G.4
Michaelides, M.5
Carter, J.M.6
-
163
-
-
75949116246
-
The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission
-
Tanimura, A., Yamazaki, M., Hashimotodani, Y., Uchigashima, M., Kawata, S., Abe, M.,et al. (2010). The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission. Neuron 65, 320-327. doi: 10.1016/j.neuron.2010.01.021
-
(2010)
Neuron
, vol.65
, pp. 320-327
-
-
Tanimura, A.1
Yamazaki, M.2
Hashimotodani, Y.3
Uchigashima, M.4
Kawata, S.5
Abe, M.6
-
164
-
-
79955958008
-
Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance
-
Taschler, U., Radner, F. P., Heier, C., Schreiber, R., Schweiger, M., Schoiswohl, G.,et al. (2011). Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance. J. Biol. Chem. 286, 17467-17477. doi: 10.1074/jbc. M110.215434
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 17467-17477
-
-
Taschler, U.1
Radner, F.P.2
Heier, C.3
Schreiber, R.4
Schweiger, M.5
Schoiswohl, G.6
-
165
-
-
84866933069
-
Adenosine A(2A)-cannabinoid CB(1) receptor interaction: an integrative mechanism in striatal glutamatergic neurotransmission
-
Tebano, M. T., Martire, A., and Popoli, P. (2012). Adenosine A(2A)-cannabinoid CB(1) receptor interaction: an integrative mechanism in striatal glutamatergic neurotransmission. Brain Res. 1476, 108-118. doi: 10.1016/j.brainres.2012.04.051
-
(2012)
Brain Res.
, vol.1476
, pp. 108-118
-
-
Tebano, M.T.1
Martire, A.2
Popoli, P.3
-
166
-
-
0030951587
-
Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice
-
Tian, M., Broxmeyer, H. E., Fan, Y., Lai, Z., Zhang, S., Aronica, S.,et al. (1997). Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice. J. Exp. Med. 185, 1517-1522. doi: 10.1084/jem.185.8.1517
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1517-1522
-
-
Tian, M.1
Broxmeyer, H.E.2
Fan, Y.3
Lai, Z.4
Zhang, S.5
Aronica, S.6
-
167
-
-
84867746610
-
Proenkephalin mediates the enduring effects of adolescent cannabis exposure associated with adult opiate vulnerability
-
Tomasiewicz, H. C., Jacobs, M. M., Wilkinson, M. B., Wilson, S. P., Nestler, E. J., and Hurd, Y. L. (2012). Proenkephalin mediates the enduring effects of adolescent cannabis exposure associated with adult opiate vulnerability. Biol. Psychiatry 72, 803-810. doi: 10.1016/j.biopsych.2012.04.026
-
(2012)
Biol. Psychiatry
, vol.72
, pp. 803-810
-
-
Tomasiewicz, H.C.1
Jacobs, M.M.2
Wilkinson, M.B.3
Wilson, S.P.4
Nestler, E.J.5
Hurd, Y.L.6
-
168
-
-
77952424429
-
The endogenous opioid system: a common substrate in drug addiction
-
Trigo, J. M., Martin-Garcia, E., Berrendero, F., Robledo, P., and Maldonado, R. (2010). The endogenous opioid system: a common substrate in drug addiction. Drug Alcohol Depend. 108, 183-194. doi: 10.1016/j.drugalcdep.2009.10.011
-
(2010)
Drug Alcohol Depend.
, vol.108
, pp. 183-194
-
-
Trigo, J.M.1
Martin-Garcia, E.2
Berrendero, F.3
Robledo, P.4
Maldonado, R.5
-
169
-
-
79961107765
-
Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways
-
Tsuboi, K., Okamoto, Y., Ikematsu, N., Inoue, M., Shimizu, Y., Uyama, T.,et al. (2011). Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and -independent pathways. Biochim. Biophys. Acta 1811, 565-577. doi: 10.1016/j.bbalip.2011.07.009
-
(2011)
Biochim. Biophys. Acta
, vol.1811
, pp. 565-577
-
-
Tsuboi, K.1
Okamoto, Y.2
Ikematsu, N.3
Inoue, M.4
Shimizu, Y.5
Uyama, T.6
-
170
-
-
34547610708
-
Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade
-
Tzschentke, T. M. (2007). Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade. Addict. Biol. 12, 227-462. doi: 10.1111/j.1369-1600.2007.00070.x
-
(2007)
Addict. Biol.
, vol.12
, pp. 227-462
-
-
Tzschentke, T.M.1
-
171
-
-
79957649283
-
Molecular and morphological configuration for 2-arachidonoylglycerol-mediated retrograde signaling at mossy cell-granule cell synapses in the dentate gyrus
-
Uchigashima, M., Yamazaki, M., Yamasaki, M., Tanimura, A., Sakimura, K., Kano, M.,et al. (2011). Molecular and morphological configuration for 2-arachidonoylglycerol-mediated retrograde signaling at mossy cell-granule cell synapses in the dentate gyrus. J. Neurosci. 31, 7700-7714. doi: 10.1523/JNEUROSCI.5665-10.2011
-
(2011)
J. Neurosci.
, vol.31
, pp. 7700-7714
-
-
Uchigashima, M.1
Yamazaki, M.2
Yamasaki, M.3
Tanimura, A.4
Sakimura, K.5
Kano, M.6
-
172
-
-
27644581965
-
Kappa- and delta-opioid receptor functional activities are increased in the caudate putamen of cannabinoid CB1 receptor knockout mice
-
Uriguen, L., Berrendero, F., Ledent, C., Maldonado, R., and Manzanares, J. (2005). Kappa- and delta-opioid receptor functional activities are increased in the caudate putamen of cannabinoid CB1 receptor knockout mice. Eur. J. Neurosci. 22, 2106-2110. doi: 10.1111/j.1460-9568.2005.04372.x
-
(2005)
Eur. J. Neurosci.
, vol.22
, pp. 2106-2110
-
-
Uriguen, L.1
Berrendero, F.2
Ledent, C.3
Maldonado, R.4
Manzanares, J.5
-
173
-
-
0034671190
-
Cannabinoid withdrawal syndrome is reduced in pre-proenkephalin knock-out mice
-
Valverde, O., Maldonado, R., Valjent, E., Zimmer, A. M., and Zimmer, A. (2000). Cannabinoid withdrawal syndrome is reduced in pre-proenkephalin knock-out mice. J. Neurosci. 20, 9284-9289.
-
(2000)
J. Neurosci.
, vol.20
, pp. 9284-9289
-
-
Valverde, O.1
Maldonado, R.2
Valjent, E.3
Zimmer, A.M.4
Zimmer, A.5
-
174
-
-
84857128654
-
CB1 receptor-deficient mice as a model for depression
-
Valverde, O., and Torrens, M. (2012). CB1 receptor-deficient mice as a model for depression. Neuroscience 204, 193-206. doi: 10.1016/j.neuroscience.2011.09.031
-
(2012)
Neuroscience
, vol.204
, pp. 193-206
-
-
Valverde, O.1
Torrens, M.2
-
175
-
-
84879413396
-
Ablation of kappa-opioid receptors from brain dopamine neurons has anxiolytic-like effects and enhances cocaine-induced plasticity
-
Van't Veer, A., Bechtholt, A. J., Onvani, S., Potter, D., Wang, Y., Liu-Chen, L. Y.,et al. (2013). Ablation of kappa-opioid receptors from brain dopamine neurons has anxiolytic-like effects and enhances cocaine-induced plasticity. Neuropsychopharmacology 38, 1585-1597. doi: 10.1038/npp.2013.58
-
(2013)
Neuropsychopharmacology
, vol.38
, pp. 1585-1597
-
-
Van't Veer, A.1
Bechtholt, A.J.2
Onvani, S.3
Potter, D.4
Wang, Y.5
Liu-Chen, L.Y.6
-
176
-
-
72449140688
-
The delta(1) opioid receptor is a heterodimer that opposes the actions of the delta(2) receptor on alcohol intake
-
van Rijn, R. M., and Whistler, J. L. (2009). The delta(1) opioid receptor is a heterodimer that opposes the actions of the delta(2) receptor on alcohol intake. Biol. Psychiatry 66, 777-784. doi: 10.1016/j.biopsych.2009.05.019
-
(2009)
Biol. Psychiatry
, vol.66
, pp. 777-784
-
-
van Rijn, R.M.1
Whistler, J.L.2
-
177
-
-
20444399468
-
Molecular and cellular basis of cannabinoid and opioid interactions
-
Vigano, D., Rubino, T., and Parolaro, D. (2005). Molecular and cellular basis of cannabinoid and opioid interactions. Pharmacol. Biochem. Behav. 81, 360-368. doi: 10.1016/j.pbb.2005.01.021
-
(2005)
Pharmacol. Biochem. Behav.
, vol.81
, pp. 360-368
-
-
Vigano, D.1
Rubino, T.2
Parolaro, D.3
-
178
-
-
37249036062
-
Manipulation of fatty acid amide hydrolase functional activity alters sensitivity and dependence to ethanol
-
Vinod, K. Y., Sanguino, E., Yalamanchili, R., Manzanares, J., and Hungund, B. L. (2008). Manipulation of fatty acid amide hydrolase functional activity alters sensitivity and dependence to ethanol. J. Neurochem. 104, 233-243. doi: 10.1111/j.1471-4159.2007.04956.x
-
(2008)
J. Neurochem.
, vol.104
, pp. 233-243
-
-
Vinod, K.Y.1
Sanguino, E.2
Yalamanchili, R.3
Manzanares, J.4
Hungund, B.L.5
-
179
-
-
84884169503
-
Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout mice
-
Weibel, R., Reiss, D., Karchewski, L., Gardon, O., Matifas, A., Filliol, D.,et al. (2013). Mu opioid receptors on primary afferent nav1.8 neurons contribute to opiate-induced analgesia: insight from conditional knockout mice. PLoS ONE 8:e74706. doi: 10.1371/journal.pone.0074706
-
(2013)
PLoS ONE
, vol.8
-
-
Weibel, R.1
Reiss, D.2
Karchewski, L.3
Gardon, O.4
Matifas, A.5
Filliol, D.6
-
180
-
-
33846360071
-
Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors
-
Wise, L. E., Shelton, C. C., Cravatt, B. F., Martin, B. R., and Lichtman, A. H. (2007). Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors. Eur. J. Pharmacol. 557, 44-48. doi: 10.1016/j.ejphar.2006.11.002
-
(2007)
Eur. J. Pharmacol.
, vol.557
, pp. 44-48
-
-
Wise, L.E.1
Shelton, C.C.2
Cravatt, B.F.3
Martin, B.R.4
Lichtman, A.H.5
-
181
-
-
24044458606
-
Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons
-
Wotherspoon, G., Fox, A., Mcintyre, P., Colley, S., Bevan, S., and Winter, J. (2005). Peripheral nerve injury induces cannabinoid receptor 2 protein expression in rat sensory neurons. Neuroscience 135, 235-245. doi: 10.1016/j.neuroscience.2005.06.009
-
(2005)
Neuroscience
, vol.135
, pp. 235-245
-
-
Wotherspoon, G.1
Fox, A.2
Mcintyre, P.3
Colley, S.4
Bevan, S.5
Winter, J.6
-
182
-
-
80052213796
-
Brain cannabinoid CB(2) receptors modulate cocaine's actions in mice
-
Xi, Z. X., Peng, X. Q., Li, X., Song, R., Zhang, H. Y., Liu, Q. R.,et al. (2011). Brain cannabinoid CB(2) receptors modulate cocaine's actions in mice. Nat. Neurosci. 14, 1160-1166. doi: 10.1038/nn.2874
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 1160-1166
-
-
Xi, Z.X.1
Peng, X.Q.2
Li, X.3
Song, R.4
Zhang, H.Y.5
Liu, Q.R.6
-
183
-
-
0032863468
-
Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin
-
Yaswen, L., Diehl, N., Brennan, M. B., and Hochgeschwender, U. (1999). Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin. Nat. Med. 5, 1066-1070. doi: 10.1038/12506
-
(1999)
Nat. Med.
, vol.5
, pp. 1066-1070
-
-
Yaswen, L.1
Diehl, N.2
Brennan, M.B.3
Hochgeschwender, U.4
-
184
-
-
80054101176
-
Postsynaptic diacylglycerol lipase mediates retrograde endocannabinoid suppression of inhibition in mouse prefrontal cortex
-
Yoshino, H., Miyamae, T., Hansen, G., Zambrowicz, B., Flynn, M., Pedicord, D.,et al. (2011). Postsynaptic diacylglycerol lipase mediates retrograde endocannabinoid suppression of inhibition in mouse prefrontal cortex. J. Physiol. 589, 4857-4884. doi: 10.1113/jphysiol.2011.212225
-
(2011)
J. Physiol.
, vol.589
, pp. 4857-4884
-
-
Yoshino, H.1
Miyamae, T.2
Hansen, G.3
Zambrowicz, B.4
Flynn, M.5
Pedicord, D.6
-
185
-
-
84855502083
-
Effects of endocannabinoid system modulation on cognitive and emotional behavior
-
Zanettini, C., Panlilio, L. V., Alicki, M., Goldberg, S. R., Haller, J., and Yasar, S. (2011). Effects of endocannabinoid system modulation on cognitive and emotional behavior. Front. Behav. Neurosci. 5:57. doi: 10.3389/fnbeh.2011.00057
-
(2011)
Front. Behav. Neurosci
, vol.5
, pp. 57
-
-
Zanettini, C.1
Panlilio, L.V.2
Alicki, M.3
Goldberg, S.R.4
Haller, J.5
Yasar, S.6
-
186
-
-
84915754556
-
Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice
-
Zhang, H. Y., Gao, M., Liu, Q. R., Bi, G. H., Li, X., Yang, H. J.,et al. (2014). Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice. Proc. Natl. Acad. Sci. U.S.A. doi: 10.1073/pnas.1413210111
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
-
-
Zhang, H.Y.1
Gao, M.2
Liu, Q.R.3
Bi, G.H.4
Li, X.5
Yang, H.J.6
-
187
-
-
0033198831
-
Retention of supraspinal delta-like analgesia and loss of morphine tolerance in delta opioid receptor knockout mice
-
Zhu, Y., King, M. A., Schuller, A. G., Nitsche, J. F., Reidl, M., Elde, R. P.,et al. (1999). Retention of supraspinal delta-like analgesia and loss of morphine tolerance in delta opioid receptor knockout mice. Neuron 24, 243-252. doi: 10.1016/S0896-6273(00)80836-3
-
(1999)
Neuron
, vol.24
, pp. 243-252
-
-
Zhu, Y.1
King, M.A.2
Schuller, A.G.3
Nitsche, J.F.4
Reidl, M.5
Elde, R.P.6
-
188
-
-
0035576146
-
Absence of delta-9-tetrahydrocannabinol dysphoric effects in dynorphin-deficient mice
-
Zimmer, A., Valjent, E., Konig, M., Zimmer, A. M., Robledo, P., Hahn, H.,et al. (2001). Absence of delta-9-tetrahydrocannabinol dysphoric effects in dynorphin-deficient mice. J. Neurosci. 21, 9499-9505.
-
(2001)
J. Neurosci.
, vol.21
, pp. 9499-9505
-
-
Zimmer, A.1
Valjent, E.2
Konig, M.3
Zimmer, A.M.4
Robledo, P.5
Hahn, H.6
-
189
-
-
0033545866
-
Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice
-
Zimmer, A., Zimmer, A. M., Hohmann, A. G., Herkenham, M., and Bonner, T. I. (1999). Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice. Proc. Natl. Acad. Sci. U.S.A. 96, 5780-5785. doi: 10.1073/pnas.96.10.5780
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 5780-5785
-
-
Zimmer, A.1
Zimmer, A.M.2
Hohmann, A.G.3
Herkenham, M.4
Bonner, T.I.5
|