Antinociceptive and hypothermic effects of salvinorin A Are abolished in a novel strain of κ-opioid receptor-1 knockout mice

Journal of Pharmacology and Experimental Therapeutics

Volumn 318, Issue 2, 2006, Pages 641-648

  Ansonoff, Michael A ^a   Zhang, Jiwen ^a,b   Czyzyk, Traci ^a   Rothman, Richard B ^c   Stewart, Jeremy ^b   Xu, Heng ^c   Zjwiony, Jordan ^a,b   Siebert, Daniel J ^d   Yang, Feng ^b   Roth, Bryan L ^b   Pintar, John E ^a,e  

^a UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^d UMDNJ Robert Wood Johnson Medical School ^*

^e RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BREMAZOCINE; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; OPIATE DERIVATIVE; SALVINORIN A; SALVINORIN B; SALVINORINYL 2 PROPIONATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; BODY TEMPERATURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG BINDING; DRUG EFFECT; DRUG INHIBITION; DRUG POTENCY; HYPOTHERMIA; IN VITRO STUDY; IN VIVO STUDY; MALE; MEXICO; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; SALVIA;

ANALGESICS; ANALGESICS, NON-NARCOTIC; ANIMALS; BODY TEMPERATURE; BRAIN; CELL LINE; CLONING, MOLECULAR; DITERPENES; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; INJECTIONS, INTRAVENOUS; MICE; MICE, KNOCKOUT; MUTATION; PAIN MEASUREMENT; PLANT LEAVES; RADIOLIGAND ASSAY; RECEPTORS, OPIOID, KAPPA; SALVIA;

EID: 33745960208     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.101998     Document Type: Article

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