Mu Opioid Receptors on Primary Afferent Nav1.8 Neurons Contribute to Opiate-Induced Analgesia: Insight from Conditional Knockout Mice

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Weibel, Raphaël ^a   Reiss, David ^a   Karchewski, Laurie ^a,c   Gardon, Olivier ^a   Matifas, Audrey ^a   Filliol, Dominique ^a   Becker, Jérôme A J ^a   Wood, John N ^b   Kieffer, Brigitte L ^a   Gaveriaux Ruff, Claire ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c ROYAL CANADIAN MOUNTED POLICE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FENTANYL; LOPERAMIDE; MESSENGER RNA; MORPHINE; MU OPIATE RECEPTOR; NARCOTIC ANALGESIC AGENT;

ADVERSE OUTCOME; ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONSTIPATION; CONTROLLED STUDY; DRUG RESPONSE; DRUG TARGETING; FEMALE; INFLAMMATORY PAIN; MALE; MOUSE; MUSCLE SPINDLE AFFERENT NERVE; NONHUMAN; PAIN; PAIN ASSESSMENT; PAIN THRESHOLD; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SPINAL GANGLION; STIMULUS RESPONSE;

ANALGESIA; ANALGESICS, OPIOID; ANIMALS; CONSTIPATION; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; FEMALE; GENE DELETION; GENE EXPRESSION; GENE KNOCKOUT TECHNIQUES; GENE ORDER; GENE TARGETING; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); MALE; MICE; MICE, KNOCKOUT; MORPHINE; NAV1.8 VOLTAGE-GATED SODIUM CHANNEL; NOCICEPTION; PAIN; PAIN MEASUREMENT; POSTERIOR HORN CELLS; PROTEIN BINDING; RECEPTORS, OPIOID, MU; SENSORY THRESHOLDS;

EID: 84884169503     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074706     Document Type: Article

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