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Volumn 2, Issue 2, 1999, Pages 151-156

Retention of heroin and morphine-6β-glucuronide analgesia in a new line of mice lacking exon 1 of MOR-1

Author keywords

[No Author keywords available]

Indexed keywords

DIAMORPHINE; MORPHINE; MORPHINE 6 GLUCURONIDE;

EID: 0033366394     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/5706     Document Type: Article
Times cited : (281)

References (30)
  • 1
    • 0027471855 scopus 로고
    • Pharmacological mechanisms of opioid analgesics
    • Pasternak, G. W. Pharmacological mechanisms of opioid analgesics. Clin. Neuropharmacol. 16, 1-18 (1993).
    • (1993) Clin. Neuropharmacol. , vol.16 , pp. 1-18
    • Pasternak, G.W.1
  • 2
    • 0002972989 scopus 로고
    • Metabolism of heroin and its pharmacological implications
    • Way, E. L., Young, J. & Kemp, J. Metabolism of heroin and its pharmacological implications. Bull. Narcotics 17, 25-33 (1965).
    • (1965) Bull. Narcotics , vol.17 , pp. 25-33
    • Way, E.L.1    Young, J.2    Kemp, J.3
  • 3
    • 0001035277 scopus 로고
    • The pharmacologic effects of heroin in relationship to its rate of biotransformation
    • Way, E., Kemp, J., Young, J. & Grasetti, D. R. The pharmacologic effects of heroin in relationship to its rate of biotransformation. Pharmacol. Exp. Ther. 129, 144-154 (1960).
    • (1960) Pharmacol. Exp. Ther. , vol.129 , pp. 144-154
    • Way, E.1    Kemp, J.2    Young, J.3    Grasetti, D.R.4
  • 4
    • 0015484902 scopus 로고
    • Blood-brain barrier: Penetration of morphine, codeine, heroin, and methadone after carotid injection
    • Oldendorf, W. H., Hyman, S., Braun, L. & Oldendorf, S. Z. Blood-brain barrier: penetration of morphine, codeine, heroin, and methadone after carotid injection. Science 178, 984-986 (1972).
    • (1972) Science , vol.178 , pp. 984-986
    • Oldendorf, W.H.1    Hyman, S.2    Braun, L.3    Oldendorf, S.Z.4
  • 5
    • 0021321402 scopus 로고    scopus 로고
    • The pharmacokinetics of heroin in patients with chronic pain
    • Inturrisi, C. E. et al. The pharmacokinetics of heroin in patients with chronic pain. N. Engl. J. Med. 310, 1213-1217 (1984).
    • N. Engl. J. Med. , vol.310 , Issue.1984 , pp. 1213-1217
    • Inturrisi, C.E.1
  • 6
    • 0021078665 scopus 로고
    • Evidence from opiate binding studies that heroin acts through its metabolites
    • Inturrisi, C. E. et al. Evidence from opiate binding studies that heroin acts through its metabolites. Life Sci. 33 Suppl 1, 773-776 (1983).
    • (1983) Life Sci. , vol.33 , Issue.SUPPL. 1 , pp. 773-776
    • Inturrisi, C.E.1
  • 7
    • 0028121645 scopus 로고
    • Blockade of morphine analgesia by an antisense oligodeoxynucleotide against the mu receptor
    • Rossi, G., Pan, Y.-X., Cheng, J. & Pasternak, G. W. Blockade of morphine analgesia by an antisense oligodeoxynucleotide against the mu receptor. Life Sci. 54, PL375-379 (1994).
    • (1994) Life Sci. , vol.54
    • Rossi, G.1    Pan, Y.-X.2    Cheng, J.3    Pasternak, G.W.4
  • 8
    • 0028856752 scopus 로고
    • Differential blockade of morphine and morphine-6 beta-glucuronide analgesia by antisense oligodeoxynucleotides directed against MOR-1 and G-protein alpha subunits in rats
    • Rossi, G. C., Standifer, K. M. & Pasternak, G. W. Differential blockade of morphine and morphine-6 beta-glucuronide analgesia by antisense oligodeoxynucleotides directed against MOR-1 and G-protein alpha subunits in rats. Neurosci. Lett. 198, 99-102 (1995).
    • (1995) Neurosci. Lett. , vol.198 , pp. 99-102
    • Rossi, G.C.1    Standifer, K.M.2    Pasternak, G.W.3
  • 9
    • 0029113905 scopus 로고
    • Antisense mapping the MOR-1 opioid receptor: Evidence for alternative splicing and a novel morphine-6 beta-glucuronide receptor
    • Rossi, G. C., Pan, Y.-X., Brown, G. P. & Pasternak, G. W. Antisense mapping the MOR-1 opioid receptor: evidence for alternative splicing and a novel morphine-6 beta-glucuronide receptor. FEBS Lett. 369, 192-196 (1995).
    • (1995) FEBS Lett. , vol.369 , pp. 192-196
    • Rossi, G.C.1    Pan, Y.-X.2    Brown, G.P.3    Pasternak, G.W.4
  • 10
    • 0030595288 scopus 로고    scopus 로고
    • Novel receptor mechanisms for heroin and morphine-6 beta-glucuronide analgesia
    • Rossi, G. C., Brown, G. P., Leventhal, L., Yang, K. & Pasternak, G. W. Novel receptor mechanisms for heroin and morphine-6 beta-glucuronide analgesia. Neurosci. Lett. 216, 1-4 (1996).
    • (1996) Neurosci. Lett. , vol.216 , pp. 1-4
    • Rossi, G.C.1    Brown, G.P.2    Leventhal, L.3    Yang, K.4    Pasternak, G.W.5
  • 11
    • 0029097278 scopus 로고
    • Mapping of opioid receptors using antisense oligodeoxynucleotides: Correlating their molecular biology and pharmacology
    • Pasternak, G. W. & Standifer, K. M. Mapping of opioid receptors using antisense oligodeoxynucleotides: correlating their molecular biology and pharmacology. Trends Pharmacol. Sci. 16, 344-350 (1995).
    • (1995) Trends Pharmacol. Sci. , vol.16 , pp. 344-350
    • Pasternak, G.W.1    Standifer, K.M.2
  • 12
    • 0027440862 scopus 로고
    • Independent expression of two pharmacologically distinct supraspinal mu analgesic systems in genetically different mouse strains
    • Pick, C. G., Nejat, R. J. & Pasternak, G. W. Independent expression of two pharmacologically distinct supraspinal mu analgesic systems in genetically different mouse strains. J. Pharmacol. Exp. Ther. 265, 166-171 (1993).
    • (1993) J. Pharmacol. Exp. Ther. , vol.265 , pp. 166-171
    • Pick, C.G.1    Nejat, R.J.2    Pasternak, G.W.3
  • 13
    • 0022272975 scopus 로고
    • Autoradiographic distribution of mu1 and mu2 opioid binding in the mouse central nervous system
    • Moskowitz, A. S. & Goodman, R. R. Autoradiographic distribution of mu1 and mu2 opioid binding in the mouse central nervous system. Brain Res. 360, 117-129 (1985).
    • (1985) Brain Res. , vol.360 , pp. 117-129
    • Moskowitz, A.S.1    Goodman, R.R.2
  • 14
    • 0030610661 scopus 로고    scopus 로고
    • 3H-morphine-6beta-glucuronide binding in brain membranes and an MOR-1-transfected cell line
    • 3H-morphine-6beta-glucuronide binding in brain membranes and an MOR-1-transfected cell line. J. Pharmacol. Exp. Ther. 282, 1291-1297 (1997).
    • (1997) J. Pharmacol. Exp. Ther. , vol.282 , pp. 1291-1297
    • Brown, G.P.1
  • 15
    • 0029837191 scopus 로고    scopus 로고
    • Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein alpha subunits
    • Standifer, K. M., Rossi, G. C. & Pasternak, G. W. Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein alpha subunits. Mol. Pharmacol. 50, 293-298 (1996).
    • (1996) Mol. Pharmacol. , vol.50 , pp. 293-298
    • Standifer, K.M.1    Rossi, G.C.2    Pasternak, G.W.3
  • 16
    • 0030911452 scopus 로고    scopus 로고
    • Antisense mapping of MOR-1 in rats: Distinguishing between morphine and morphine-6beta-glucuronide antinociception
    • Rossi, G. C. et al. Antisense mapping of MOR-1 in rats: distinguishing between morphine and morphine-6beta-glucuronide antinociception. J. Pharmacol. Exp. Ther. 281, 109-114 (1997).
    • (1997) J. Pharmacol. Exp. Ther. , vol.281 , pp. 109-114
    • Rossi, G.C.1
  • 17
    • 0027380497 scopus 로고
    • Molecular biology of opioid receptors
    • Reisine, T. & Bell, G. I. Molecular biology of opioid receptors. Trends Neurosci. 16, 506-510 (1993).
    • (1993) Trends Neurosci. , vol.16 , pp. 506-510
    • Reisine, T.1    Bell, G.I.2
  • 19
    • 0028847941 scopus 로고
    • Cloning and expression of an isoform of the rat mu opioid receptor (rMOR1B) which differs in agonist induced desensitization from rMOR1
    • Zimprich, A., Simon, T. & Hollt, V. Cloning and expression of an isoform of the rat mu opioid receptor (rMOR1B) which differs in agonist induced desensitization from rMOR1. FEBS Lett. 359, 142-146 (1995).
    • (1995) FEBS Lett. , vol.359 , pp. 142-146
    • Zimprich, A.1    Simon, T.2    Hollt, V.3
  • 20
    • 0028062727 scopus 로고
    • Expression of two variants of the human mu opioid receptor mRNA in SK-N-SH cells and human brain
    • Bare, L. A., Mansson, E. & Yang, D. Expression of two variants of the human mu opioid receptor mRNA in SK-N-SH cells and human brain. FEBS Lett. 354, 213-216 (1994).
    • (1994) FEBS Lett. , vol.354 , pp. 213-216
    • Bare, L.A.1    Mansson, E.2    Yang, D.3
  • 21
    • 0029852678 scopus 로고    scopus 로고
    • Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene
    • Matthes, H. W. et al. Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature 383, 819-823 (1996).
    • (1996) Nature , vol.383 , pp. 819-823
    • Matthes, H.W.1
  • 22
    • 0031030042 scopus 로고    scopus 로고
    • Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia
    • Sora, I. et al. Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia. Proc. Natl. Acad. Sci. USA 94, 1544-1549 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 1544-1549
    • Sora, I.1
  • 23
    • 0030951587 scopus 로고    scopus 로고
    • Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice
    • Tian, M. et al. Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice. J. Exp. Med. 185, 1517-1522 (1997).
    • (1997) J. Exp. Med. , vol.185 , pp. 1517-1522
    • Tian, M.1
  • 24
    • 0032031040 scopus 로고    scopus 로고
    • Mu opioid receptor knockout in mice: Effects on ligand-induced analgesia and morphine lethality
    • Loh, H. H. et al. Mu opioid receptor knockout in mice: effects on ligand-induced analgesia and morphine lethality. Mol. Brain Res. 54, 321-326 (1998).
    • (1998) Mol. Brain Res. , vol.54 , pp. 321-326
    • Loh, H.H.1
  • 25
    • 0028985401 scopus 로고
    • An antisense oligodeoxynucleotide to mu-opioid receptors inhibits mu-opioid receptor agonist-induced analgesia in rats
    • Chen, X. H. et al. An antisense oligodeoxynucleotide to mu-opioid receptors inhibits mu-opioid receptor agonist-induced analgesia in rats. Eur. J. Pharmacol. 275, 105-108 (1995).
    • (1995) Eur. J. Pharmacol. , vol.275 , pp. 105-108
    • Chen, X.H.1
  • 26
    • 0024369341 scopus 로고
    • Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite
    • Paul, D., Standifer, K. M., Inturrisi, C. E. & Pasternak, G. W. Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite. J. Pharmacol. Exp. Ther. 251, 477-483 (1989).
    • (1989) J. Pharmacol. Exp. Ther. , vol.251 , pp. 477-483
    • Paul, D.1    Standifer, K.M.2    Inturrisi, C.E.3    Pasternak, G.W.4
  • 27
    • 0030811735 scopus 로고    scopus 로고
    • 3-Methoxynaltrexone, a selective heroin/morphine-6beta-glucuronide antagonist
    • Brown, G. P. et al. 3-Methoxynaltrexone, a selective heroin/morphine-6beta-glucuronide antagonist. FEBS Lett. 412, 35-38 (1997).
    • (1997) FEBS Lett. , vol.412 , pp. 35-38
    • Brown, G.P.1
  • 28
    • 0027769462 scopus 로고
    • Targeted disruption of the neuronal nitric oxide synthase gene
    • Huang, P. L., Dawson, T. M., Bredt, D. S., Snyder, S. H. & Fishman, M. C. Targeted disruption of the neuronal nitric oxide synthase gene. Cell 75, 1273-1286 (1993).
    • (1993) Cell , vol.75 , pp. 1273-1286
    • Huang, P.L.1    Dawson, T.M.2    Bredt, D.S.3    Snyder, S.H.4    Fishman, M.C.5
  • 29
    • 13344277364 scopus 로고    scopus 로고
    • Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domains
    • Brenman, J. E. et al. Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domains. Cell 84, 757-767 (1996).
    • (1996) Cell , vol.84 , pp. 757-767
    • Brenman, J.E.1


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