-
1
-
-
0027471855
-
Pharmacological mechanisms of opioid analgesics
-
Pasternak, G. W. Pharmacological mechanisms of opioid analgesics. Clin. Neuropharmacol. 16, 1-18 (1993).
-
(1993)
Clin. Neuropharmacol.
, vol.16
, pp. 1-18
-
-
Pasternak, G.W.1
-
2
-
-
0002972989
-
Metabolism of heroin and its pharmacological implications
-
Way, E. L., Young, J. & Kemp, J. Metabolism of heroin and its pharmacological implications. Bull. Narcotics 17, 25-33 (1965).
-
(1965)
Bull. Narcotics
, vol.17
, pp. 25-33
-
-
Way, E.L.1
Young, J.2
Kemp, J.3
-
3
-
-
0001035277
-
The pharmacologic effects of heroin in relationship to its rate of biotransformation
-
Way, E., Kemp, J., Young, J. & Grasetti, D. R. The pharmacologic effects of heroin in relationship to its rate of biotransformation. Pharmacol. Exp. Ther. 129, 144-154 (1960).
-
(1960)
Pharmacol. Exp. Ther.
, vol.129
, pp. 144-154
-
-
Way, E.1
Kemp, J.2
Young, J.3
Grasetti, D.R.4
-
4
-
-
0015484902
-
Blood-brain barrier: Penetration of morphine, codeine, heroin, and methadone after carotid injection
-
Oldendorf, W. H., Hyman, S., Braun, L. & Oldendorf, S. Z. Blood-brain barrier: penetration of morphine, codeine, heroin, and methadone after carotid injection. Science 178, 984-986 (1972).
-
(1972)
Science
, vol.178
, pp. 984-986
-
-
Oldendorf, W.H.1
Hyman, S.2
Braun, L.3
Oldendorf, S.Z.4
-
5
-
-
0021321402
-
The pharmacokinetics of heroin in patients with chronic pain
-
Inturrisi, C. E. et al. The pharmacokinetics of heroin in patients with chronic pain. N. Engl. J. Med. 310, 1213-1217 (1984).
-
N. Engl. J. Med.
, vol.310
, Issue.1984
, pp. 1213-1217
-
-
Inturrisi, C.E.1
-
6
-
-
0021078665
-
Evidence from opiate binding studies that heroin acts through its metabolites
-
Inturrisi, C. E. et al. Evidence from opiate binding studies that heroin acts through its metabolites. Life Sci. 33 Suppl 1, 773-776 (1983).
-
(1983)
Life Sci.
, vol.33
, Issue.SUPPL. 1
, pp. 773-776
-
-
Inturrisi, C.E.1
-
7
-
-
0028121645
-
Blockade of morphine analgesia by an antisense oligodeoxynucleotide against the mu receptor
-
Rossi, G., Pan, Y.-X., Cheng, J. & Pasternak, G. W. Blockade of morphine analgesia by an antisense oligodeoxynucleotide against the mu receptor. Life Sci. 54, PL375-379 (1994).
-
(1994)
Life Sci.
, vol.54
-
-
Rossi, G.1
Pan, Y.-X.2
Cheng, J.3
Pasternak, G.W.4
-
8
-
-
0028856752
-
Differential blockade of morphine and morphine-6 beta-glucuronide analgesia by antisense oligodeoxynucleotides directed against MOR-1 and G-protein alpha subunits in rats
-
Rossi, G. C., Standifer, K. M. & Pasternak, G. W. Differential blockade of morphine and morphine-6 beta-glucuronide analgesia by antisense oligodeoxynucleotides directed against MOR-1 and G-protein alpha subunits in rats. Neurosci. Lett. 198, 99-102 (1995).
-
(1995)
Neurosci. Lett.
, vol.198
, pp. 99-102
-
-
Rossi, G.C.1
Standifer, K.M.2
Pasternak, G.W.3
-
9
-
-
0029113905
-
Antisense mapping the MOR-1 opioid receptor: Evidence for alternative splicing and a novel morphine-6 beta-glucuronide receptor
-
Rossi, G. C., Pan, Y.-X., Brown, G. P. & Pasternak, G. W. Antisense mapping the MOR-1 opioid receptor: evidence for alternative splicing and a novel morphine-6 beta-glucuronide receptor. FEBS Lett. 369, 192-196 (1995).
-
(1995)
FEBS Lett.
, vol.369
, pp. 192-196
-
-
Rossi, G.C.1
Pan, Y.-X.2
Brown, G.P.3
Pasternak, G.W.4
-
10
-
-
0030595288
-
Novel receptor mechanisms for heroin and morphine-6 beta-glucuronide analgesia
-
Rossi, G. C., Brown, G. P., Leventhal, L., Yang, K. & Pasternak, G. W. Novel receptor mechanisms for heroin and morphine-6 beta-glucuronide analgesia. Neurosci. Lett. 216, 1-4 (1996).
-
(1996)
Neurosci. Lett.
, vol.216
, pp. 1-4
-
-
Rossi, G.C.1
Brown, G.P.2
Leventhal, L.3
Yang, K.4
Pasternak, G.W.5
-
11
-
-
0029097278
-
Mapping of opioid receptors using antisense oligodeoxynucleotides: Correlating their molecular biology and pharmacology
-
Pasternak, G. W. & Standifer, K. M. Mapping of opioid receptors using antisense oligodeoxynucleotides: correlating their molecular biology and pharmacology. Trends Pharmacol. Sci. 16, 344-350 (1995).
-
(1995)
Trends Pharmacol. Sci.
, vol.16
, pp. 344-350
-
-
Pasternak, G.W.1
Standifer, K.M.2
-
12
-
-
0027440862
-
Independent expression of two pharmacologically distinct supraspinal mu analgesic systems in genetically different mouse strains
-
Pick, C. G., Nejat, R. J. & Pasternak, G. W. Independent expression of two pharmacologically distinct supraspinal mu analgesic systems in genetically different mouse strains. J. Pharmacol. Exp. Ther. 265, 166-171 (1993).
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.265
, pp. 166-171
-
-
Pick, C.G.1
Nejat, R.J.2
Pasternak, G.W.3
-
13
-
-
0022272975
-
Autoradiographic distribution of mu1 and mu2 opioid binding in the mouse central nervous system
-
Moskowitz, A. S. & Goodman, R. R. Autoradiographic distribution of mu1 and mu2 opioid binding in the mouse central nervous system. Brain Res. 360, 117-129 (1985).
-
(1985)
Brain Res.
, vol.360
, pp. 117-129
-
-
Moskowitz, A.S.1
Goodman, R.R.2
-
14
-
-
0030610661
-
3H-morphine-6beta-glucuronide binding in brain membranes and an MOR-1-transfected cell line
-
3H-morphine-6beta-glucuronide binding in brain membranes and an MOR-1-transfected cell line. J. Pharmacol. Exp. Ther. 282, 1291-1297 (1997).
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.282
, pp. 1291-1297
-
-
Brown, G.P.1
-
15
-
-
0029837191
-
Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein alpha subunits
-
Standifer, K. M., Rossi, G. C. & Pasternak, G. W. Differential blockade of opioid analgesia by antisense oligodeoxynucleotides directed against various G protein alpha subunits. Mol. Pharmacol. 50, 293-298 (1996).
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 293-298
-
-
Standifer, K.M.1
Rossi, G.C.2
Pasternak, G.W.3
-
16
-
-
0030911452
-
Antisense mapping of MOR-1 in rats: Distinguishing between morphine and morphine-6beta-glucuronide antinociception
-
Rossi, G. C. et al. Antisense mapping of MOR-1 in rats: distinguishing between morphine and morphine-6beta-glucuronide antinociception. J. Pharmacol. Exp. Ther. 281, 109-114 (1997).
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.281
, pp. 109-114
-
-
Rossi, G.C.1
-
17
-
-
0027380497
-
Molecular biology of opioid receptors
-
Reisine, T. & Bell, G. I. Molecular biology of opioid receptors. Trends Neurosci. 16, 506-510 (1993).
-
(1993)
Trends Neurosci.
, vol.16
, pp. 506-510
-
-
Reisine, T.1
Bell, G.I.2
-
18
-
-
0028119767
-
An opiate-receptor gene family reunion
-
Uhl, G. R., Childers, S. & Pasternak, G. An opiate-receptor gene family reunion. Trends Neurosci. 17, 89-93 (1994).
-
(1994)
Trends Neurosci.
, vol.17
, pp. 89-93
-
-
Uhl, G.R.1
Childers, S.2
Pasternak, G.3
-
19
-
-
0028847941
-
Cloning and expression of an isoform of the rat mu opioid receptor (rMOR1B) which differs in agonist induced desensitization from rMOR1
-
Zimprich, A., Simon, T. & Hollt, V. Cloning and expression of an isoform of the rat mu opioid receptor (rMOR1B) which differs in agonist induced desensitization from rMOR1. FEBS Lett. 359, 142-146 (1995).
-
(1995)
FEBS Lett.
, vol.359
, pp. 142-146
-
-
Zimprich, A.1
Simon, T.2
Hollt, V.3
-
20
-
-
0028062727
-
Expression of two variants of the human mu opioid receptor mRNA in SK-N-SH cells and human brain
-
Bare, L. A., Mansson, E. & Yang, D. Expression of two variants of the human mu opioid receptor mRNA in SK-N-SH cells and human brain. FEBS Lett. 354, 213-216 (1994).
-
(1994)
FEBS Lett.
, vol.354
, pp. 213-216
-
-
Bare, L.A.1
Mansson, E.2
Yang, D.3
-
21
-
-
0029852678
-
Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene
-
Matthes, H. W. et al. Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature 383, 819-823 (1996).
-
(1996)
Nature
, vol.383
, pp. 819-823
-
-
Matthes, H.W.1
-
22
-
-
0031030042
-
Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia
-
Sora, I. et al. Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia. Proc. Natl. Acad. Sci. USA 94, 1544-1549 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 1544-1549
-
-
Sora, I.1
-
23
-
-
0030951587
-
Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice
-
Tian, M. et al. Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice. J. Exp. Med. 185, 1517-1522 (1997).
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1517-1522
-
-
Tian, M.1
-
24
-
-
0032031040
-
Mu opioid receptor knockout in mice: Effects on ligand-induced analgesia and morphine lethality
-
Loh, H. H. et al. Mu opioid receptor knockout in mice: effects on ligand-induced analgesia and morphine lethality. Mol. Brain Res. 54, 321-326 (1998).
-
(1998)
Mol. Brain Res.
, vol.54
, pp. 321-326
-
-
Loh, H.H.1
-
25
-
-
0028985401
-
An antisense oligodeoxynucleotide to mu-opioid receptors inhibits mu-opioid receptor agonist-induced analgesia in rats
-
Chen, X. H. et al. An antisense oligodeoxynucleotide to mu-opioid receptors inhibits mu-opioid receptor agonist-induced analgesia in rats. Eur. J. Pharmacol. 275, 105-108 (1995).
-
(1995)
Eur. J. Pharmacol.
, vol.275
, pp. 105-108
-
-
Chen, X.H.1
-
26
-
-
0024369341
-
Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite
-
Paul, D., Standifer, K. M., Inturrisi, C. E. & Pasternak, G. W. Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite. J. Pharmacol. Exp. Ther. 251, 477-483 (1989).
-
(1989)
J. Pharmacol. Exp. Ther.
, vol.251
, pp. 477-483
-
-
Paul, D.1
Standifer, K.M.2
Inturrisi, C.E.3
Pasternak, G.W.4
-
27
-
-
0030811735
-
3-Methoxynaltrexone, a selective heroin/morphine-6beta-glucuronide antagonist
-
Brown, G. P. et al. 3-Methoxynaltrexone, a selective heroin/morphine-6beta-glucuronide antagonist. FEBS Lett. 412, 35-38 (1997).
-
(1997)
FEBS Lett.
, vol.412
, pp. 35-38
-
-
Brown, G.P.1
-
28
-
-
0027769462
-
Targeted disruption of the neuronal nitric oxide synthase gene
-
Huang, P. L., Dawson, T. M., Bredt, D. S., Snyder, S. H. & Fishman, M. C. Targeted disruption of the neuronal nitric oxide synthase gene. Cell 75, 1273-1286 (1993).
-
(1993)
Cell
, vol.75
, pp. 1273-1286
-
-
Huang, P.L.1
Dawson, T.M.2
Bredt, D.S.3
Snyder, S.H.4
Fishman, M.C.5
-
29
-
-
13344277364
-
Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domains
-
Brenman, J. E. et al. Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domains. Cell 84, 757-767 (1996).
-
(1996)
Cell
, vol.84
, pp. 757-767
-
-
Brenman, J.E.1
|