Implication of endogenous β-endorphin in the inhibition of the morphine-induced rewarding effect by the direct activation of spinal protein kinase C in mice

Neuroscience Letters

Volumn 433, Issue 1, 2008, Pages 54-58

  Niikura, Keiichi ^a   Narita, Minoru ^a   Okutsu, Daiki ^a   Tsurukawa, Yuri ^a   Nanjo, Kana ^a   Kurahashi, Kana ^a   Kobayashi, Yasuhisa ^a   Suzuki, Tsutomu ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Endorphin; Morphine; Neuropathic pain like state; Protein kinase C

Indexed keywords

BETA ENDORPHIN; MORPHINE; PHORBOL DIBUTYRATE; PROTEIN KINASE C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; FEMALE; GENE DELETION; HYPERALGESIA; MALE; MOUSE; NONHUMAN; PAIN; PRIORITY JOURNAL; SPINAL CORD;

ANIMALS; BETA-ENDORPHIN; BRAIN; ENZYME ACTIVATION; ENZYME ACTIVATORS; FEMALE; HYPERALGESIA; INJECTIONS, SPINAL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MORPHINE; MORPHINE DEPENDENCE; NARCOTICS; NEURAL INHIBITION; PAIN; PROTEIN KINASE C; REWARD; SPINAL CORD;

EID: 39149103043     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.12.042     Document Type: Article

References (24)

1. Coderre T.J. Contribution of protein kinase C to central sensitization and persistent pain following tissue injury. Neurosci. Lett. 140 (1992) 181-184
2. Funada M., Suzuki T., Narita M., Misawa M., and Nagase H. Blockade of morphine reward through the activation of kappa-opioid receptors in mice. Neuropharmacology 32 (1993) 1315-1323
3. Hofmann J. The potential for isoenzyme-selective modulation of protein kinase C. FASEB J. 11 (1997) 649-669
4. Hylden J.L., and Wilcox G.L. Intrathecal morphine in mice: a new technique. Eur. J. Pharmacol. 67 (1980) 313-316
5. Malmberg A.B., Chen C., Tonegawa S., and Basbaum A.I. Preserved acute pain and reduced neuropathic pain in mice lacking PKCgamma. Science 278 (1997) 279-283
6. Mao J., Price D.D., Phillips L.L., Lu J., and Mayer D.J. Increases in protein kinase C gamma immunoreactivity in the spinal cord dorsal horn of rats with painful mononeuropathy. Neurosci. Lett. 198 (1995) 75-78
7. McBurney M.W., Sutherland L.C., Adra C.N., Leclair B., Rudnicki M.A., and Jardine K. The mouse Pgk-1 gene promoter contains an upstream activator sequence. Nucleic Acids Res. 19 (1991) 5755-5761
8. Mochly-Rosen D., and Kauvar L.M. Modulating protein kinase C signal transduction. Adv. Pharmacol. 44 (1998) 91-145
9. Narita M., Funada M., and Suzuki T. Regulations of opioid dependence by opioid receptor types. Pharmacol. Ther. 89 (2001) 1-15
10. Narita M., Imai S., Oe K., Kubota C., Yajima Y., Yamazaki M., and Suzuki T. Induction of c-fos expression in the mouse brain associated with hyperalgesia induced by intrathecal injection of protein kinase C activator. Brain Res. 1015 (2004) 189-193
11. Narita M., Kishimoto Y., Ise Y., Yajima Y., Misawa K., and Suzuki T. Direct evidence for the involvement of the mesolimbic kappa-opioid system in the morphine-induced rewarding effect under an inflammatory pain-like state. Neuropsychopharmacology 30 (2005) 111-118
12. M. Narita, A. Nakamura, M. Ozaki, S. Imai, K. Miyoshi, M. Suzuki, T. Suzuki, Comparative pharmacological profiles of morphine and oxycodone under a neuropathic pain-like state in mice: evidence for less sensitivity to morphine, Neuropsychopharmacology, in press.
13. Narita M., Oe K., Kato H., Shibasaki M., Yajima Y., Yamazaki M., and Suzuki T. Implication of spinal protein kinase C in the suppression of morphine-induced rewarding effect under a neuropathic pain-like state in mice. Neuroscience 125 (2004) 545-551
14. Narita M., Suzuki M., Imai S., Ozaki S., Kishimoto Y., Oe K., Yajima Y., Yamazaki M., and Suzuki T. Molecular mechanism of changes in the morphine-induced pharmacological actions under chronic pain-like state: suppression of dopaminergic transmission in the brain. Life Sci. 74 (2004) 2655-2673
15. Oe K., Narita M., Imai S., Shibasaki M., Kubota C., Kasukawa A., Hamaguchi M., Yajima Y., Yamazaki M., and Suzuki T. Inhibition of the morphine-induced rewarding effect by direct activation of spinal protein kinase C in mice. Psychopharmacology (Berl.) 177 (2004) 55-60
16. Ohsawa M., Narita M., Mizoguchi H., Cheng E., and Tseng L.F. Reduced hyperalgesia induced by nerve injury, but not by inflammation in mice lacking protein kinase C gamma isoform. Eur. J. Pharmacol. 429 (2001) 157-160
17. Ohsawa M., Narita M., Mizoguchi H., Suzuki T., and Tseng L.F. Involvement of spinal protein kinase C in thermal hyperalgesia evoked by partial sciatic nerve ligation, but not by inflammation in the mouse. Eur. J. Pharmacol. 403 (2000) 81-85
18. Ozaki S., Narita M., Iino M., Miyoshi K., and Suzuki T. Suppression of the morphine-induced rewarding effect and G-protein activation in the lower midbrain following nerve injury in the mouse: involvement of G-protein-coupled receptor kinase 2. Neuroscience 116 (2003) 89-97
19. Ozaki S., Narita M., Iino M., Sugita J., Matsumura Y., and Suzuki T. Suppression of the morphine-induced rewarding effect in the rat with neuropathic pain: implication of the reduction in mu-opioid receptor functions in the ventral tegmental area. J. Neurochem. 82 (2002) 1192-1198
20. Rubinstein M., Mogil J.S., Japon M., Chan E.C., Allen R.G., and Low M.J. Absence of opioid stress-induced analgesia in mice lacking beta-endorphin by site-directed mutagenesis. Proc. Natl. Acad. Sci. U.S.A. 93 (1996) 3995-4000
21. Sluka K.A., Rees H., Chen P.S., Tsuruoka M., and Willis W.D. Capsaicin-induced sensitization of primate spinothalamic tract cells is prevented by a protein kinase C inhibitor. Brain Res. 772 (1997) 82-86
22. Suzuki T., Masukawa Y., and Misawa M. Drug interactions in the reinforcing effects of over-the-counter cough syrups. Psychopharmacology (Berl.) 102 (1990) 438-442
23. Way K.J., Chou E., and King G.L. Identification of PKC-isoform-specific biological actions using pharmacological approaches. Trends Pharmacol. Sci. 21 (2000) 181-187
24. Yajima Y., Narita M., Shimamura M., Kubota C., and Suzuki T. Differential involvement of spinal protein kinase C and protein kinase A in neuropathic and inflammatory pain in mice. Brain Res. 992 (2003) 288-293