Parental THC exposure leads to compulsive heroin-seeking and altered striatal synaptic plasticity in the subsequent generation

Neuropsychopharmacology

Volumn 39, Issue 6, 2014, Pages 1315-1323

  Szutorisz, Henrietta ^a   DiNieri, Jennifer A ^a   Sweet, Eric ^a   Egervari, Gabor ^a   Michaelides, Michael ^a   Carter, Jenna M ^a   Ren, Yanhua ^a   Miller, Michael L ^a   Blitzer, Robert D ^a   Hurd, Yasmin L ^a,b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

addiction; cannabis; cross generational transmission; development; striatum; synaptic plasticity

Indexed keywords

DIAMORPHINE; DRONABINOL; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PSYCHOTROPIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR DISORDER; BRAIN ELECTROPHYSIOLOGY; CANNABINOID RECEPTOR GENE; DOPAMINE RECEPTOR GENE; DRUG SEEKING BEHAVIOR; FEMALE; GENE; GENE EXPRESSION; GLUTAMATERGIC RECEPTOR GENE; MALE; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; RAT; STRIATE CORTEX; WITHDRAWAL SYNDROME; ANIMAL; COMPULSION; CORPUS STRIATUM; ENVIRONMENTAL EXPOSURE; HEROIN DEPENDENCE; LONG EVANS RAT; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; STEREOTYPY; SYNAPSE;

ANIMALS; COMPULSIVE BEHAVIOR; CORPUS STRIATUM; DRONABINOL; DRUG-SEEKING BEHAVIOR; FEMALE; HEROIN DEPENDENCE; MALE; MATERNAL EXPOSURE; NEURONAL PLASTICITY; PATERNAL EXPOSURE; PSYCHOTROPIC DRUGS; RATS; RATS, LONG-EVANS; RECEPTORS, N-METHYL-D-ASPARTATE; RNA, MESSENGER; STEREOTYPED BEHAVIOR; SUBSTANCE WITHDRAWAL SYNDROME; SYNAPSES;

EID: 84900791580     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2013.352     Document Type: Article

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